| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Leranth, R P Verte. Median raphe serotonergic innervation of medial septum/diagonal band of broca (MSDB) parvalbumin-containing neurons: possible involvement of the MSDB in the desynchronization of the hippocampal EEG. The Journal of comparative neurology. vol 410. issue 4. 1999-08-03. PMID:10398050. |
these observations indicate that 5-ht has a dual action on the activity of hippocampal principal cells: 1) an inhibition of the input sector by activation of hippocampal gaba neurons that terminate exclusively on apical dendrites of pyramidal cells, and 2) a disinhibition of the output sector of principal neurons. |
1999-08-03 |
2023-08-12 |
rat |
| R L Macdonald, J Kapu. Acute cellular alterations in the hippocampus after status epilepticus. Epilepsia. vol 40 Suppl 1. 1999-08-03. PMID:10421557. |
recent evidence suggests the presence of multiple gaba(a) receptor isoforms in the hippocampus with different sensitivity to benzodiazepines but similar sensitivity to barbiturates, thus explaining why the two drug classes might have different clinical effects. |
1999-08-03 |
2023-08-12 |
rat |
| R L Macdonald, J Kapu. Acute cellular alterations in the hippocampus after status epilepticus. Epilepsia. vol 40 Suppl 1. 1999-08-03. PMID:10421557. |
the loss of sensitivity of the animals to diazepam during status epilepticus was accompanied by an alteration in the functional properties of hippocampal dentate granule cell gaba(a) receptors. |
1999-08-03 |
2023-08-12 |
rat |
| R L Macdonald, J Kapu. Acute cellular alterations in the hippocampus after status epilepticus. Epilepsia. vol 40 Suppl 1. 1999-08-03. PMID:10421557. |
therefore, the prolonged seizures of status epilepticus rapidly altered the functional properties of hippocampal dentate granule cell gaba(a) receptors, possibly explaining why benzodiazepines and barbiturates may not be equally effective during treatment of the prolonged seizures of status epilepticus. |
1999-08-03 |
2023-08-12 |
rat |
| D A Coulte. Chronic epileptogenic cellular alterations in the limbic system after status epilepticus. Epilepsia. vol 40 Suppl 1. 1999-08-03. PMID:10421558. |
the presence of zinc sensitive gaba receptors combined with the presence of zinc-containing "sprouted" mossy fiber terminals innervating the proximal dendrites of dgcs in the post-se epileptic hippocampus prompted the development of the hypothesis that repetitive activation of the dg in the epileptic brain could result in the release of zine. |
1999-08-03 |
2023-08-12 |
Not clear |
| E I Tietz, X Huang, S Chen, W F Ferenca. Temporal and regional regulation of alpha1, beta2 and beta3, but not alpha2, alpha4, alpha5, alpha6, beta1 or gamma2 GABA(A) receptor subunit messenger RNAs following one-week oral flurazepam administration. Neuroscience. vol 91. issue 1. 1999-08-02. PMID:10336082. |
the effect of prolonged benzodiazepine administration on gaba(a) receptor subunit (alpha1-6, beta1-3, gamma2) messenger rnas was investigated in the rat hippocampus and cortex, among other brain areas. |
1999-08-02 |
2023-08-12 |
rat |
| C Leranth, D Carpi, G Buzsaki, J Kis. The entorhino-septo-supramammillary nucleus connection in the rat: morphological basis of a feedback mechanism regulating hippocampal theta rhythm. Neuroscience. vol 88. issue 3. 1999-08-02. PMID:10363811. |
light and electron microscopic immunostaining for calretinin, in combination with antero- and retrograde tracer techniques, postembedding immunostaining for gaba and the transmitter specific [3h]d-aspartate retrograde radiolabeling, as well as a co-localization experiment for calretinin and glutamate decarboxylase in rat supramammillary and septal neurons, demonstrated that: (i) a large population of entorhinal cells that forms asymmetric synaptic contacts on calretinin-containing neurons located at the border between the medial and lateral septal areas contains calretinin and are aspartate/glutamatergic; (ii) the overwhelming majority of calretinin-immunoreactive cells located at the border between the lateral and medial septal area are gabaergic; (iii) these neurons can be retrogradely labeled from the supramammillary area; (iv) anterogradely labeled axons originating in the border between the medial and lateral septum are gabaergic and (v) terminate on supramammillary area non-gabaergic, calretinin-containing neurons, which are known to project to the septal complex and hippocampus. |
1999-08-02 |
2023-08-12 |
rat |
| I Chaudieu, A Priva. Neuroprotection of cultured foetal rat hippocampal cells against glucose deprivation: are GABAergic neurons less vulnerable or more sensitive to TCP protection? The European journal of neuroscience. vol 11. issue 7. 1999-07-30. PMID:10383631. |
primary cultures from the rat hippocampus (21 days in vitro) were deprived of glucose for 4 h and then were returned to the standard medium for 24 or 48 h. survival of the gabaergic neuronal population was evaluated both by measuring [3h]gaba uptake and by counting gad65-immunostained cells. |
1999-07-30 |
2023-08-12 |
rat |
| M Park-Chung, A Malayev, R H Purdy, T T Gibbs, D H Far. Sulfated and unsulfated steroids modulate gamma-aminobutyric acidA receptor function through distinct sites. Brain research. vol 830. issue 1. 1999-07-29. PMID:10350561. |
modulation by endogenous and synthetic steroids of the response to exogenous or synaptically released gaba was examined in primary chick spinal cord and rat hippocampal neurons, and in xenopus laevis oocytes expressing alpha1beta2gamma2s gabaa receptors. |
1999-07-29 |
2023-08-12 |
rat |
| K Richter, K Langnaese, M R Kreutz, G Olias, R Zhai, H Scheich, C C Garner, E D Gundelfinge. Presynaptic cytomatrix protein bassoon is localized at both excitatory and inhibitory synapses of rat brain. The Journal of comparative neurology. vol 408. issue 3. 1999-07-28. PMID:10340516. |
in cultured hippocampal neurons, bassoon was found to colocalize with gaba(a) and glutamate (glur1) receptors. |
1999-07-28 |
2023-08-12 |
rat |
| H Z Yin, S L Sensi, S G Carriedo, J H Weis. Dendritic localization of Ca(2+)-permeable AMPA/kainate channels in hippocampal pyramidal neurons. The Journal of comparative neurology. vol 409. issue 2. 1999-07-28. PMID:10379918. |
although it is well established that cortical and hippocampal gamma-aminobutyric acid (gaba)-ergic neurons generally have large numbers of ca(2+)-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa)/kainate channels (ca-a/k channels), their presence on pyramidal neurons is controversial. |
1999-07-28 |
2023-08-12 |
Not clear |
| S Gobaille, V Hechler, C Andriamampandry, V Kemmel, M Maitr. gamma-Hydroxybutyrate modulates synthesis and extracellular concentration of gamma-aminobutyric acid in discrete rat brain regions in vivo. The Journal of pharmacology and experimental therapeutics. vol 290. issue 1. 1999-07-26. PMID:10381791. |
in particular, radioactive gaba was not detected in the hippocampus. |
1999-07-26 |
2023-08-12 |
rat |
| R A Cunha, J A Ribeir. Facilitation of GABA release by arachidonic acid in rat hippocampal synaptosomes. The European journal of neuroscience. vol 11. issue 6. 1999-07-01. PMID:10336686. |
facilitation of gaba release by arachidonic acid in rat hippocampal synaptosomes. |
1999-07-01 |
2023-08-12 |
rat |
| R A Cunha, J A Ribeir. Facilitation of GABA release by arachidonic acid in rat hippocampal synaptosomes. The European journal of neuroscience. vol 11. issue 6. 1999-07-01. PMID:10336686. |
in this study, we found that aa (10 microm) increased the basal outflow (19 +/- 4%) and the k+-evoked release of [3h]gaba (38 +/- 3%) from rat hippocampal synaptosomes. |
1999-07-01 |
2023-08-12 |
rat |
| R A Cunha, J A Ribeir. Facilitation of GABA release by arachidonic acid in rat hippocampal synaptosomes. The European journal of neuroscience. vol 11. issue 6. 1999-07-01. PMID:10336686. |
these results show that exogenously added and endogenously produced aa increased basal outflow and k+-evoked release of [3h]gaba from rat hippocampal synaptosomes. |
1999-07-01 |
2023-08-12 |
rat |
| K Sasaki, S Hatta, M Haga, H Ohshik. Effects of bilobalide on gamma-aminobutyric acid levels and glutamic acid decarboxylase in mouse brain. European journal of pharmacology. vol 367. issue 2-3. 1999-06-22. PMID:10078989. |
this study examined the effects of bilobalide on the level of gaba and glutamate, the activity and the amount of glutamic acid decarboxylase (ec 4.1.1.15), and the function of gaba(a) receptors in the hippocampus, cerebral cortex and striatum of the mouse. |
1999-06-22 |
2023-08-12 |
mouse |
| K Sasaki, S Hatta, M Haga, H Ohshik. Effects of bilobalide on gamma-aminobutyric acid levels and glutamic acid decarboxylase in mouse brain. European journal of pharmacology. vol 367. issue 2-3. 1999-06-22. PMID:10078989. |
gaba levels, glutamic acid decarboxylase activity, and the protein amount of 67 kda glutamic acid decarboxylase in the hippocampus of mice treated with bilobalide (30 mg/kg, p.o., once a day for 4 days) were significantly higher than those in controls. |
1999-06-22 |
2023-08-12 |
mouse |
| K Sasaki, S Hatta, M Haga, H Ohshik. Effects of bilobalide on gamma-aminobutyric acid levels and glutamic acid decarboxylase in mouse brain. European journal of pharmacology. vol 367. issue 2-3. 1999-06-22. PMID:10078989. |
however, there were no significant differences in glutamate levels or, the number and the dissociation constants of gaba(a) receptors in the hippocampus between control and bilobalide-treated mice. |
1999-06-22 |
2023-08-12 |
mouse |
| L Jóźwiak, M Sieklucka-Dziuba, Z Kleinro. Behavioral studies of the effects of moderate oligemic hypoxia caused by bilateral clamping of carotid arteries in mice. Impairment of spatial working memory. Polish journal of pharmacology. vol 50. issue 4-5. 1999-06-22. PMID:10091712. |
the experiments carried out on albino swiss mice indicated that bilateral clamping of carotid arteries (bcca) for 30 min caused no neuronal damage but produced an increase in gaba content in the hippocampus, striatum and frontal cortex. |
1999-06-22 |
2023-08-12 |
mouse |
| K Kobayashi, Y Okad. Excitatory effects of adenosine are not mediated by inhibition of GABAergic system in slices of superior colliculus and hippocampus from guinea pig. Neuroscience letters. vol 264. issue 1-3. 1999-06-17. PMID:10320008. |
to investigate the possible involvement of disinhibition by adenosine on gamma-aminobutyric acid (gaba) -ergic action, the effects of adenosine and picrotoxin, a gaba antagonist, were studied using slices of sc and hippocampus of the guinea pig. |
1999-06-17 |
2023-08-12 |
Not clear |