| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mathew Blurton-Jones, Mark H Tuszynsk. Estrogen receptor-beta colocalizes extensively with parvalbumin-labeled inhibitory neurons in the cortex, amygdala, basal forebrain, and hippocampal formation of intact and ovariectomized adult rats. The Journal of comparative neurology. vol 452. issue 3. 2002-10-30. PMID:12353223. |
estrogen has been reported to regulate the activity of gamma-aminobutyric acid (gaba)ergic interneurons within the hippocampus, basal forebrain, and hypothalamus of adult rodents. |
2002-10-30 |
2023-08-12 |
rat |
| S Grottoli, R Giordano, B Maccagno, M Pellegrino, E Ghigo, E Arva. The stimulatory effect of canrenoate, a mineralocorticoid antagonist, on the activity of the hypothalamus-pituitary-adrenal axis is abolished by alprazolam, a benzodiazepine, in humans. The Journal of clinical endocrinology and metabolism. vol 87. issue 10. 2002-10-30. PMID:12364444. |
benzodiazepines, namely alprazolam, activate central gamma-aminobutyric acid (gaba)ergic receptors, which are mainly distributed in the hippocampus. |
2002-10-30 |
2023-08-12 |
Not clear |
| Nam-Sik Woo, Jianming Lu, Roger England, Robert McClellan, Samuel Dufour, David B Mount, Ariel Y Deutch, David M Lovinger, Eric Delpir. Hyperexcitability and epilepsy associated with disruption of the mouse neuronal-specific K-Cl cotransporter gene. Hippocampus. vol 12. issue 2. 2002-10-23. PMID:12000122. |
application of picrotoxin, a blocker of the gaba(a) receptor, further increased hyperexcitability in homozygous hippocampal sections. |
2002-10-23 |
2023-08-12 |
mouse |
| Qi-Ying Liu, Yoong H Chang, Anne E Schaffner, Susan V Smith, Jeffery L Barke. Allopregnanolone activates GABA(A) receptor/Cl(-) channels in a multiphasic manner in embryonic rat hippocampal neurons. Journal of neurophysiology. vol 88. issue 3. 2002-10-23. PMID:12205136. |
allopregnanolone activates gaba(a) receptor/cl(-) channels in a multiphasic manner in embryonic rat hippocampal neurons. |
2002-10-23 |
2023-08-12 |
rat |
| Qi-Ying Liu, Yoong H Chang, Anne E Schaffner, Susan V Smith, Jeffery L Barke. Allopregnanolone activates GABA(A) receptor/Cl(-) channels in a multiphasic manner in embryonic rat hippocampal neurons. Journal of neurophysiology. vol 88. issue 3. 2002-10-23. PMID:12205136. |
we used patch-clamp recording to study the interaction with gaba(a) receptor/cl(-) channels expressed by embryonic hippocampal neurons differentiating in culture and nonneuronal cells transfected with gaba(a) receptor subunits. |
2002-10-23 |
2023-08-12 |
rat |
| Qi-Ying Liu, Yoong H Chang, Anne E Schaffner, Susan V Smith, Jeffery L Barke. Allopregnanolone activates GABA(A) receptor/Cl(-) channels in a multiphasic manner in embryonic rat hippocampal neurons. Journal of neurophysiology. vol 88. issue 3. 2002-10-23. PMID:12205136. |
the results indicate that allopregnanolone interacts with gaba(a) receptor/cl(-) channels expressed by embryonic hippocampal neurons in multiple ways, some of which are mediated by g proteins. |
2002-10-23 |
2023-08-12 |
rat |
| Tae-Cheon Kang, Seung-Kook Park, In-Koo Hwang, Sung-Jin An, Soo Young Choi, Sung-Woo Cho, Moo Ho Wo. Spatial and temporal alterations in the GABA shunt in the gerbil hippocampus following transient ischemia. Brain research. vol 944. issue 1-2. 2002-10-11. PMID:12106661. |
spatial and temporal alterations in the gaba shunt in the gerbil hippocampus following transient ischemia. |
2002-10-11 |
2023-08-12 |
Not clear |
| Abdulmonem Al-Hayani, Stephen N Davie. Effect of cannabinoids on synaptic transmission in the rat hippocampal slice is temperature-dependent. European journal of pharmacology. vol 442. issue 1-2. 2002-10-08. PMID:12020681. |
we have previously reported that the synthetic cannabinoid r-(+)-[2,3-dihydro-5-methyl-3-[(morpholinyl)methyl]pyrrolo[1,2,3-de]-1,4-benzoxazin-yl]-(1-naphthalenyl)methanone mesylate (win55,212-2) causes a selective inhibition of paired pulse depression of population spikes recorded from the ca1 region of rat hippocampal slices maintained at 28-30 degrees c. we now show that this effect is highly temperature-dependent and that win55,212-2 actually increases paired pulse depression of population spikes recorded from slices maintained at 35 degrees c. this temperature dependence was found to correlate with the effects of the known gamma-amino butyric acid (gaba)-uptake inhibitors, nipecotic acid and guvacine, which were without effect at 28-30 degrees c, but increased paired pulse depression at 35 degrees c. the results show that the effects of cannabinoids on synaptic transmission in the hippocampal slice are highly temperature-dependent and it is suggested that this is due to the presence of increased gaba uptake at higher temperatures. |
2002-10-08 |
2023-08-12 |
rat |
| Letícia V Costa-Lotufo, Marta Maria de F Fonteles, Iri Sandro Pampolha Lima, Aline A de Oliveira, Viviane S Nascimento, Veralice M S de Bruin, Glauce S B Vian. Attenuating effects of melatonin on pilocarpine-induced seizures in rats. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. vol 131. issue 4. 2002-10-03. PMID:11976067. |
melatonin partially recovered [3h]gaba binding in the hippocampus in the presence of pilocarpine-induced seizures, and intensified pilocarpine effects in the striatum of adult rats. |
2002-10-03 |
2023-08-12 |
rat |
| F M Leslie, K A Gallardo, M K Par. Nicotinic acetylcholine receptor-mediated release of [3H]norepinephrine from developing and adult rat hippocampus: direct and indirect mechanisms. Neuropharmacology. vol 42. issue 5. 2002-09-10. PMID:11985823. |
these findings are consistent with the hypothesis that nicotine-induced gaba release serves as an additional stimulus for [(3)h]norepinephrine secretion within rat hippocampus. |
2002-09-10 |
2023-08-12 |
rat |
| David J Bailey, Julie E Tetzlaff, James M Cook, Xiaohui He, Fred J Helmstette. Effects of hippocampal injections of a novel ligand selective for the alpha 5 beta 2 gamma 2 subunits of the GABA/benzodiazepine receptor on Pavlovian conditioning. Neurobiology of learning and memory. vol 78. issue 1. 2002-09-10. PMID:12071663. |
these data provide further evidence for the involvement of hippocampal gaba(a)/benzodiazepine receptors in learning and anxiety. |
2002-09-10 |
2023-08-12 |
rat |
| Maria Martire, Debora Altobelli, Carla Cannizzaro, Silvia Maurizi, Paolo Prezios. Prenatal diazepam exposure functionally alters the GABA(A) receptor that modulates [3H]noradrenaline release from rat hippocampal synaptosomes. Developmental neuroscience. vol 24. issue 1. 2002-09-06. PMID:12145412. |
prenatal diazepam exposure functionally alters the gaba(a) receptor that modulates [3h]noradrenaline release from rat hippocampal synaptosomes. |
2002-09-06 |
2023-08-12 |
rat |
| Maria Martire, Debora Altobelli, Carla Cannizzaro, Silvia Maurizi, Paolo Prezios. Prenatal diazepam exposure functionally alters the GABA(A) receptor that modulates [3H]noradrenaline release from rat hippocampal synaptosomes. Developmental neuroscience. vol 24. issue 1. 2002-09-06. PMID:12145412. |
the method used - perfusion of rat hippocampal nerve terminals labeled with [3h]noradrenaline (na) - allowed us to evaluate the effects of dz on a specific native gaba(a) receptor subtype which is located on hippocampal noradrenergic nerve endings and mediates the release of na. |
2002-09-06 |
2023-08-12 |
rat |
| Jehuda P Sepkuty, Akiva S Cohen, Christine Eccles, Azhar Rafiq, Kevin Behar, Raquelli Ganel, Douglas A Coulter, Jeffrey D Rothstei. A neuronal glutamate transporter contributes to neurotransmitter GABA synthesis and epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 15. 2002-09-03. PMID:12151515. |
there was a 50% loss of hippocampal gaba levels associated with knockdown of eaac1, and newly synthesized gaba from extracellular glutamate was significantly impaired by reduction of eaac1 expression. |
2002-09-03 |
2023-08-12 |
rat |
| L V Lopes, R A Cunha, B Kull, B B Fredholm, J A Ribeir. Adenosine A(2A) receptor facilitation of hippocampal synaptic transmission is dependent on tonic A(1) receptor inhibition. Neuroscience. vol 112. issue 2. 2002-08-29. PMID:12044450. |
the a(2a) receptor agonist, cgs 21680 (10 nm), facilitated synaptic transmission in the ca1 area of rat hippocampal slices (by 14%), independent of whether or not gabaergic transmission was blocked by the gaba(a) and gaba(b) receptor antagonists, picrotoxin (50 microm) and cgp 55845 (1 microm), respectively. |
2002-08-29 |
2023-08-12 |
rat |
| M M Kraus, H Pras. Involvement of nitric oxide, cyclic GMP and phosphodiesterase 5 in excitatory amino acid and GABA release in the nucleus accumbens evoked by activation of the hippocampal fimbria. Neuroscience. vol 112. issue 2. 2002-08-29. PMID:12044451. |
involvement of nitric oxide, cyclic gmp and phosphodiesterase 5 in excitatory amino acid and gaba release in the nucleus accumbens evoked by activation of the hippocampal fimbria. |
2002-08-29 |
2023-08-12 |
rat |
| Alberto Muñoz, Jon Ignacio Arellano, Javier DeFelip. GABABR1 receptor protein expression in human mesial temporal cortex: changes in temporal lobe epilepsy. The Journal of comparative neurology. vol 449. issue 2. 2002-08-27. PMID:12115687. |
immunocytochemistry was used to examine gamma-aminobutyric acid beta (gaba)(b)r1a-b protein expression in the human hippocampal formation (including dentate gyrus, hippocampus proper, subicular complex, and entorhinal cortex) and perirhinal cortex. |
2002-08-27 |
2023-08-12 |
human |
| Alberto Muñoz, Jon Ignacio Arellano, Javier DeFelip. GABABR1 receptor protein expression in human mesial temporal cortex: changes in temporal lobe epilepsy. The Journal of comparative neurology. vol 449. issue 2. 2002-08-27. PMID:12115687. |
interestingly, the hippocampal formation of epileptic patients (n = 8) with hippocampal sclerosis showed similar intensity of gaba(b)r1a-b immunostaining in the surviving neurons located within or adjacent to those regions presenting neuronal loss than in the controls. |
2002-08-27 |
2023-08-12 |
human |
| Alberto Muñoz, Jon Ignacio Arellano, Javier DeFelip. GABABR1 receptor protein expression in human mesial temporal cortex: changes in temporal lobe epilepsy. The Journal of comparative neurology. vol 449. issue 2. 2002-08-27. PMID:12115687. |
therefore, alterations in inhibitory synaptic transmission through gaba(b) receptors appears to affect differentially certain hippocampal circuits in a population of epileptic patients. |
2002-08-27 |
2023-08-12 |
human |
| Shozo Jinno, Toshio Kosak. Patterns of expression of calcium binding proteins and neuronal nitric oxide synthase in different populations of hippocampal GABAergic neurons in mice. The Journal of comparative neurology. vol 449. issue 1. 2002-08-20. PMID:12115690. |
we examined the expression of calcium binding proteins parvalbumin (pv), calretinin (cr), and calbindin d28k (cb), and neuronal nitric oxide synthase (nnos) in gamma-aminobutyric acid (gaba)ergic neurons of the mouse hippocampus, with particular reference to areal and dorsoventral differences. |
2002-08-20 |
2023-08-12 |
mouse |