| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shu P Li, Moon S Park, Jong Y Bahk, Myeong O Ki. Chronic nicotine and smoking exposure decreases GABA(B1) receptor expression in the rat hippocampus. Neuroscience letters. vol 334. issue 2. 2003-01-24. PMID:12435490. |
in this study, the effects of nicotine and different doses of smoking on gaba(b1) expression in the rat hippocampus have been examined using in situ hybridization and rnase protection assay. |
2003-01-24 |
2023-08-12 |
rat |
| Shu P Li, Moon S Park, Jong Y Bahk, Myeong O Ki. Chronic nicotine and smoking exposure decreases GABA(B1) receptor expression in the rat hippocampus. Neuroscience letters. vol 334. issue 2. 2003-01-24. PMID:12435490. |
gaba(b1) receptor mrnas were intensely expressed in the ca1, ca2, ca3, and dentate gyrus areas of the hippocampus. |
2003-01-24 |
2023-08-12 |
rat |
| Shu P Li, Moon S Park, Jong Y Bahk, Myeong O Ki. Chronic nicotine and smoking exposure decreases GABA(B1) receptor expression in the rat hippocampus. Neuroscience letters. vol 334. issue 2. 2003-01-24. PMID:12435490. |
nicotine and smoking doses dependently decreased gaba(b1) receptor expression in the hippocampus. |
2003-01-24 |
2023-08-12 |
rat |
| Maurizio Cammalleri, Alfredo Brancucci, Fulvia Berton, Antonella Loche, Gian Luigi Gessa, Walter Francescon. Gamma-hydroxybutyrate reduces GABA(A)-mediated inhibitory postsynaptic potentials in the CA1 region of hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 27. issue 6. 2003-01-24. PMID:12464453. |
gamma-hydroxybutyrate reduces gaba(a)-mediated inhibitory postsynaptic potentials in the ca1 region of hippocampus. |
2003-01-24 |
2023-08-12 |
Not clear |
| K M Frick, S M Fernandez, S C Bulinsk. Estrogen replacement improves spatial reference memory and increases hippocampal synaptophysin in aged female mice. Neuroscience. vol 115. issue 2. 2003-01-23. PMID:12421621. |
at the conclusion of testing, levels of the presynaptic protein synaptophysin, and activities of the synthetic enzymes for acetylcholine and gaba, were measured in the hippocampus and neocortex. |
2003-01-23 |
2023-08-12 |
mouse |
| K M Frick, S M Fernandez, S C Bulinsk. Estrogen replacement improves spatial reference memory and increases hippocampal synaptophysin in aged female mice. Neuroscience. vol 115. issue 2. 2003-01-23. PMID:12421621. |
the results suggest that: (1) estrogen can profoundly improve spatial reference memory in aged females, and (2) this improvement may be related to increased hippocampal synaptic plasticity, but not modulation of the synthetic enzymes for acetylcholine and gaba. |
2003-01-23 |
2023-08-12 |
mouse |
| A E Stacey, G L Woodhall, R S G Jone. Activation of neurokinin-1 receptors promotes GABA release at synapses in the rat entorhinal cortex. Neuroscience. vol 115. issue 2. 2003-01-23. PMID:12421623. |
the results demonstrate that neurokinin-1 receptor activation promotes the release of gaba at synapses on principal neurones in both entorhinal cortex and hippocampus. |
2003-01-23 |
2023-08-12 |
rat |
| D Seto, W-H Zheng, A McNicoll, B Collier, R Quirion, S Ka. Insulin-like growth factor-I inhibits endogenous acetylcholine release from the rat hippocampal formation: possible involvement of GABA in mediating the effects. Neuroscience. vol 115. issue 2. 2003-01-23. PMID:12421625. |
in the present study, we have characterized the possible involvement of gaba in igf-i-mediated inhibition of ach release and measured the effects of this growth factor on choline acetyltransferase (chat) activity and high-affinity choline uptake in the hippocampus of the adult rat brain. |
2003-01-23 |
2023-08-12 |
rat |
| D Seto, W-H Zheng, A McNicoll, B Collier, R Quirion, S Ka. Insulin-like growth factor-I inhibits endogenous acetylcholine release from the rat hippocampal formation: possible involvement of GABA in mediating the effects. Neuroscience. vol 115. issue 2. 2003-01-23. PMID:12421625. |
the inhibitory effects of igf-i on hippocampal ach release were not additive to those of either muscimol or baclofen, but were attenuated by gaba antagonists, bicuculline and phaclofen. |
2003-01-23 |
2023-08-12 |
rat |
| D Seto, W-H Zheng, A McNicoll, B Collier, R Quirion, S Ka. Insulin-like growth factor-I inhibits endogenous acetylcholine release from the rat hippocampal formation: possible involvement of GABA in mediating the effects. Neuroscience. vol 115. issue 2. 2003-01-23. PMID:12421625. |
furthermore, the evidence that effects of igf-i could be modulated, at least in part, by gaba antagonists suggest that the release of gaba and the activation of its receptors may possibly be involved in mediating the inhibitory effects of igf-i on hippocampal ach release. |
2003-01-23 |
2023-08-12 |
rat |
| Jacky Y T Yeung, Kevin J Canning, Guoyun Zhu, Peter Pennefather, John F MacDonald, Beverley A Orse. Tonically activated GABAA receptors in hippocampal neurons are high-affinity, low-conductance sensors for extracellular GABA. Molecular pharmacology. vol 63. issue 1. 2003-01-09. PMID:12488530. |
tonically activated gabaa receptors in hippocampal neurons are high-affinity, low-conductance sensors for extracellular gaba. |
2003-01-09 |
2023-08-12 |
mouse |
| Jacky Y T Yeung, Kevin J Canning, Guoyun Zhu, Peter Pennefather, John F MacDonald, Beverley A Orse. Tonically activated GABAA receptors in hippocampal neurons are high-affinity, low-conductance sensors for extracellular GABA. Molecular pharmacology. vol 63. issue 1. 2003-01-09. PMID:12488530. |
in the hippocampus, two distinct forms of gabaergic inhibition have been identified, phasic inhibitory postsynaptic currents that are the consequence of the vesicular release of gaba and a tonic conductance that is activated by low ambient concentrations of extracellular gaba. |
2003-01-09 |
2023-08-12 |
mouse |
| Jacky Y T Yeung, Kevin J Canning, Guoyun Zhu, Peter Pennefather, John F MacDonald, Beverley A Orse. Tonically activated GABAA receptors in hippocampal neurons are high-affinity, low-conductance sensors for extracellular GABA. Molecular pharmacology. vol 63. issue 1. 2003-01-09. PMID:12488530. |
gaba was applied to hippocampal neurons to investigate the properties of synaptic and extrasynaptic receptors. |
2003-01-09 |
2023-08-12 |
mouse |
| Jacky Y T Yeung, Kevin J Canning, Guoyun Zhu, Peter Pennefather, John F MacDonald, Beverley A Orse. Tonically activated GABAA receptors in hippocampal neurons are high-affinity, low-conductance sensors for extracellular GABA. Molecular pharmacology. vol 63. issue 1. 2003-01-09. PMID:12488530. |
thus, specialized gabaa receptors with an apparent higher affinity for gaba that do not readily desensitize mediate the persistent tonic conductance in hippocampal neurons. |
2003-01-09 |
2023-08-12 |
mouse |
| Thomas Roskoden, Karl Zilles, Axel Schleicher, Herbert Schwegle. Transient postnatal thyroxine treatment leads to variation in transmitter binding site densities in the hippocampus of rats. Neuroscience letters. vol 333. issue 1. 2002-12-26. PMID:12401551. |
in contrast, binding site densities for nmda in the entire hippocampus and for ampa in the dentate gyrus were reduced, whereas binding site densities for m2 and gaba(a) remained unchanged. |
2002-12-26 |
2023-08-12 |
rat |
| G Maccaferri, R Dingledin. Complex effects of CNQX on CA1 interneurons of the developing rat hippocampus. Neuropharmacology. vol 43. issue 4. 2002-12-24. PMID:12367599. |
however, despite the increase of sipsc frequency, cnqx-induced depolarization is sufficient to selectively generate firing in interneurons and thus modify the network properties mediated by gaba(a) receptors in the hippocampus. |
2002-12-24 |
2023-08-12 |
rat |
| Marylka Uusisaari, Sergei Smirnov, Juha Voipio, Kai Kail. Spontaneous epileptiform activity mediated by GABA(A) receptors and gap junctions in the rat hippocampal slice following long-term exposure to GABA(B) antagonists. Neuropharmacology. vol 43. issue 4. 2002-12-24. PMID:12367602. |
spontaneous epileptiform activity mediated by gaba(a) receptors and gap junctions in the rat hippocampal slice following long-term exposure to gaba(b) antagonists. |
2002-12-24 |
2023-08-12 |
rat |
| Marylka Uusisaari, Sergei Smirnov, Juha Voipio, Kai Kail. Spontaneous epileptiform activity mediated by GABA(A) receptors and gap junctions in the rat hippocampal slice following long-term exposure to GABA(B) antagonists. Neuropharmacology. vol 43. issue 4. 2002-12-24. PMID:12367602. |
we show now that exposure of a rat hippocampal slice to gaba(b) receptor antagonists (cgp 55845a and cgp 35348) in the absence of ionotropic glutamatergic transmission leads to a progressive synchronization of spontaneous interneuronal activity. |
2002-12-24 |
2023-08-12 |
rat |
| B J Van Sickle, A S Cox, K Schak, L John Greenfield, E I Tiet. Chronic benzodiazepine administration alters hippocampal CA1 neuron excitability: NMDA receptor function and expression(1). Neuropharmacology. vol 43. issue 4. 2002-12-24. PMID:12367605. |
concurrently, gaba(a) receptor-mediated inhibition is reduced and ampa receptor-mediated excitation is selectively enhanced in ca1 pyramidal neurons in hippocampal slices. |
2002-12-24 |
2023-08-12 |
rat |
| M Gulinello, Q H Gong, S S Smit. Progesterone withdrawal increases the alpha4 subunit of the GABA(A) receptor in male rats in association with anxiety and altered pharmacology - a comparison with female rats. Neuropharmacology. vol 43. issue 4. 2002-12-24. PMID:12367616. |
withdrawal from the neurosteroid 3alpha,5alpha-allopregnanolone after chronic administration of progesterone increases anxiety in female rats and up-regulates the alpha4 subunit of the gaba(a) receptor (gaba(a)-r) in the hippocampus. |
2002-12-24 |
2023-08-12 |
rat |