| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shamseddin Ahmadi, Shahin Amiri, Fatemeh Rafieenia, Jalal Rostamzade. Gene Expression Profile of Calcium/Calmodulin-Dependent Protein Kinase IIα in Rat's Hippocampus during Morphine Withdrawal. Basic and clinical neuroscience. vol 4. issue 2. 2014-10-22. PMID:25337341. |
calcium/calmodulin-dependent protein kinase ii (camkii) which is highly expressed in the hippocampus is known to play a pivotal role in reward-related memories and morphine dependence. |
2014-10-22 |
2023-08-13 |
rat |
| Wei Lu, Latika Khatri, Edward B Zif. Trafficking of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPA) receptor subunit GluA2 from the endoplasmic reticulum is stimulated by a complex containing Ca2+/calmodulin-activated kinase II (CaMKII) and PICK1 protein and by release of Ca2+ from internal stores. The Journal of biological chemistry. vol 289. issue 27. 2014-10-14. PMID:24831007. |
here we show that glua2 trafficking from the endoplasmic reticulum (er) to the plasma membrane of cultured hippocampal neurons requires ca(2+) release from internal stores, the activity of ca(2+)/calmodulin activated kinase ii (camkii), and glua2 interaction with the pdz protein, pick1. |
2014-10-14 |
2023-08-13 |
Not clear |
| Steven J Coultrap, Ronald K Freund, Heather O'Leary, Jennifer L Sanderson, Katherine W Roche, Mark L Dell'Acqua, K Ulrich Baye. Autonomous CaMKII mediates both LTP and LTD using a mechanism for differential substrate site selection. Cell reports. vol 6. issue 3. 2014-10-08. PMID:24485660. |
traditionally, hippocampal long-term potentiation (ltp) of synaptic strength requires ca(2+)/calmodulin (cam)-dependent protein kinase ii (camkii) and other kinases, whereas long-term depression (ltd) requires phosphatases. |
2014-10-08 |
2023-08-12 |
Not clear |
| Yun Tian, Yasushi Yabuki, Shigeki Moriguchi, Kohji Fukunaga, Pei-Jiang Mao, Ling-Juan Hong, Ying-Mei Lu, Rui Wang, Muhammad Masood Ahmed, Mei-Hua Liao, Ji-Yun Huang, Rui-Ting Zhang, Tian-Yi Zhou, Sen Long, Feng Ha. Melatonin reverses the decreases in hippocampal protein serine/threonine kinases observed in an animal model of autism. Journal of pineal research. vol 56. issue 1. 2014-08-25. PMID:23952810. |
we found that chronic melatonin (1.0 or 5.0 mg/kg/day, 28 days) treatment significantly rescued valproic acid (vpa, 600 mg/kg)-induced decreases in camkii (thr286), nmdar1 (ser896), and pka (thr197) phosphorylation in the hippocampus without affecting total protein levels. |
2014-08-25 |
2023-08-12 |
rat |
| Nan Lin, Xiao-dong Pan, Ai-qin Chen, Yuan-gui Zhu, Ming Wu, Jing Zhang, Xiao-chun Che. Tripchlorolide improves age-associated cognitive deficits by reversing hippocampal synaptic plasticity impairment and NMDA receptor dysfunction in SAMP8 mice. Behavioural brain research. vol 258. 2014-07-31. PMID:24140565. |
moreover, it upregulated the levels of phospho-nmdar1, postsynaptic density-95 (psd-95), phospho-calcium-calmodulin dependent kinase ii (camkii), phospho-creb and brain derived neurotrophic factor (bdnf) in the hippocampus. |
2014-07-31 |
2023-08-12 |
mouse |
| J-H Tao-Cheng, Y Yang, K U Bayer, T S Reese, A Dosemec. Effects of CaMKII inhibitor tatCN21 on activity-dependent redistribution of CaMKII in hippocampal neurons. Neuroscience. vol 244. 2014-06-02. PMID:23583761. |
effects of camkii inhibitor tatcn21 on activity-dependent redistribution of camkii in hippocampal neurons. |
2014-06-02 |
2023-08-12 |
Not clear |
| J-H Tao-Cheng, Y Yang, K U Bayer, T S Reese, A Dosemec. Effects of CaMKII inhibitor tatCN21 on activity-dependent redistribution of CaMKII in hippocampal neurons. Neuroscience. vol 244. 2014-06-02. PMID:23583761. |
here we use preembedding immunogold electron microscopy to examine the effect of tatcn21 on the redistribution of camkii in cultured hippocampal neurons. |
2014-06-02 |
2023-08-12 |
Not clear |
| Walaiporn Tongjaroenbuangam, Nootchanart Ruksee, Thanutchaporn Mahanam, Piyarat Govitrapon. Melatonin attenuates dexamethasone-induced spatial memory impairment and dexamethasone-induced reduction of synaptic protein expressions in the mouse brain. Neurochemistry international. vol 63. issue 5. 2014-06-02. PMID:24036059. |
furthermore, dex reduced brain-derived neurotrophic factor (bdnf), n-methyl-d-aspartate (nmda) receptor subunit (nr2a/b), calcium/calmodulin-dependent protein kinase ii (camkii) in both the prefrontal cortex and hippocampus and synaptophysin in the prefrontal cortex. |
2014-06-02 |
2023-08-12 |
mouse |
| Yijung Yang, Jung-Hwa Tao-Cheng, K Ulrich Bayer, Thomas S Reese, Ayse Dosemec. Camkii-mediated phosphorylation regulates distributions of Syngap-α1 and -α2 at the postsynaptic density. PloS one. vol 8. issue 8. 2014-05-14. PMID:23967245. |
application of tatcn21, a cell-penetrating inhibitor of camkii, to hippocampal neuronal cultures blocks nmda-induced redistribution of syngap-α1 and syngap-α2. |
2014-05-14 |
2023-08-12 |
rat |
| Shigeki Moriguchi, Hideaki Tagashira, Yuzuru Sasaki, Jay Z Yeh, Hiroyuki Sakagami, Toshio Narahashi, Kohji Fukunag. CaMKII activity is essential for improvement of memory-related behaviors by chronic rivastigmine treatment. Journal of neurochemistry. vol 128. issue 6. 2014-05-14. PMID:24164423. |
taken together, the stimulation of camkii activity in the hippocampus is essential for rivastigmine-induced memory improvement in obx mice. |
2014-05-14 |
2023-08-12 |
mouse |
| Jin-Dong Ding, Mary B Kennedy, Richard J Weinber. Subcellular organization of camkii in rat hippocampal pyramidal neurons. The Journal of comparative neurology. vol 521. issue 15. 2014-04-11. PMID:23749614. |
we therefore examined the subcellular localization of camkii in ca1 stratum radiatum of adult rat hippocampus, by using immuno-electron microscopy after chemical fixation. |
2014-04-11 |
2023-08-12 |
rat |
| Qing Lu, Valerie A Harris, Xutong Sun, Yali Hou, Stephen M Blac. Ca²⁺/calmodulin-dependent protein kinase II contributes to hypoxic ischemic cell death in neonatal hippocampal slice cultures. PloS one. vol 8. issue 8. 2014-04-08. PMID:23976956. |
here we show that camkii activity is stimulated in rat hippocampal slice culture exposed to oxygen glucose deprivation (ogd) to mimic the condition of hi. |
2014-04-08 |
2023-08-12 |
rat |
| Xiaoxue Xu, Feng Guo, Xintong Lv, Rui Feng, Dongyu Min, Lihua Ma, Yajing Liu, Jinsheng Zhao, Lei Wang, Tianbao Chen, Chris Shaw, Liying Hao, Jiqun Ca. Abnormal changes in voltage-gated sodium channels Na(V)1.1, Na(V)1.2, Na(V)1.3, Na(V)1.6 and in calmodulin/calmodulin-dependent protein kinase II, within the brains of spontaneously epileptic rats and tremor rats. Brain research bulletin. vol 96. 2014-03-19. PMID:23608115. |
increased expression of the four vgsc subtypes and cam, accompanied by a decrease in camkii was observed in the hippocampus of both the sers and the trm rats. |
2014-03-19 |
2023-08-12 |
rat |
| Jian-feng Ji, Sheng-jun Ji, Rui Sun, Kun Li, Yuan Zhang, Li-yuan Zhang, Ye Tia. Forced running exercise attenuates hippocampal neurogenesis impairment and the neurocognitive deficits induced by whole-brain irradiation via the BDNF-mediated pathway. Biochemical and biophysical research communications. vol 443. issue 2. 2014-03-10. PMID:24333433. |
immunofluorescence was used to evaluate the changes in hippocampal neurogenesis and western blotting was used to assess changes in the levels of mature brain-derived neurotrophic factor (bdnf), phosphorylated tyrosine receptor kinase b (trkb) receptor, protein kinase b (akt), extracellular signal-regulated kinase (erk), calcium-calmodulin dependent kinase (camkii), camp-calcium response element binding protein (creb) in the bdnf-pcreb signaling. |
2014-03-10 |
2023-08-12 |
rat |
| Dongyu Min, Xiaoyuan Mao, Kuncan Wu, Yonggang Cao, Feng Guo, Shu Zhu, Ni Xie, Lei Wang, Tianbao Chen, Chris Shaw, Jiqun Ca. Donepezil attenuates hippocampal neuronal damage and cognitive deficits after global cerebral ischemia in gerbils. Neuroscience letters. vol 510. issue 1. 2014-01-31. PMID:22240104. |
these results suggest that donepezil attenuates the memory deficit induced by transient global cerebral ischemia and this neuroprotection may be associated with the phosphorylation of camkii and cerb in the hippocampus. |
2014-01-31 |
2023-08-12 |
Not clear |
| Naoki Nakaya, Afia Sultana, Jeeva Munasinghe, Aiwu Cheng, Mark P Mattson, Stanislav I Tomare. Deletion in the N-terminal half of olfactomedin 1 modifies its interaction with synaptic proteins and causes brain dystrophy and abnormal behavior in mice. Experimental neurology. vol 250. 2014-01-30. PMID:24095980. |
modified interaction of olfm1 with binding targets led to an increase in intracellular ca(2+) concentration and activation of erk1/2, mek1 and camkii in the hippocampus and olfactory bulb of olfm1 mutant mice compared with their wild-type littermates. |
2014-01-30 |
2023-08-12 |
mouse |
| Naoki Nakaya, Afia Sultana, Jeeva Munasinghe, Aiwu Cheng, Mark P Mattson, Stanislav I Tomare. Deletion in the N-terminal half of olfactomedin 1 modifies its interaction with synaptic proteins and causes brain dystrophy and abnormal behavior in mice. Experimental neurology. vol 250. 2014-01-30. PMID:24095980. |
excessive activation of the camkii and ras-erk pathways in the olfm1 mutant olfactory bulb and hippocampus by elevated intracellular calcium may contribute to the abnormal behavior and olfactory activity of olfm1 mutant mice. |
2014-01-30 |
2023-08-12 |
mouse |
| Andrew S Karls, Michelle Mynlief. Nonspecific, reversible inhibition of voltage-gated calcium channels by CaMKII inhibitor CK59. Cellular and molecular neurobiology. vol 33. issue 5. 2014-01-29. PMID:23657616. |
the use of another camkii inhibitor, cell-permeable autocamtide-2 related inhibitory peptide ii (ant-aip-ii), failed to similarly decrease calcium current or entry in hippocampal cultures, as shown by ratiometric calcium imaging and whole-cell patch clamp electrophysiology. |
2014-01-29 |
2023-08-12 |
Not clear |
| Kelsey Barcomb, Steven J Coultrap, K Ulrich Baye. Enzymatic activity of CaMKII is not required for its interaction with the glutamate receptor subunit GluN2B. Molecular pharmacology. vol 84. issue 6. 2014-01-06. PMID:24056996. |
however, neither h7 nor sta prevented ca²⁺-induced translocation of camkii to glun2b in heterologous cells or to synapses in hippocampal neurons. |
2014-01-06 |
2023-08-12 |
Not clear |
| Shigeki Moriguchi, Yasuharu Shinoda, Yui Yamamoto, Yuzuru Sasaki, Kosuke Miyajima, Hideaki Tagashira, Kohji Fukunag. Stimulation of the sigma-1 receptor by DHEA enhances synaptic efficacy and neurogenesis in the hippocampal dentate gyrus of olfactory bulbectomized mice. PloS one. vol 8. issue 4. 2013-11-05. PMID:23593332. |
we previously reported that stimulation of the sigma-1 receptor by dhea improves cognitive function by activating calcium/calmodulin-dependent protein kinase ii (camkii), protein kinase c and extracellular signal-regulated kinase in the hippocampus in olfactory bulbectomized (obx) mice. |
2013-11-05 |
2023-08-12 |
mouse |