| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Takeshi Kanno, Tadashi Shimizu, Akito Tanaka, Takaaki Nishimoto, Tomoyuki Nishizak. Free fatty acid derivative HUHS2002 potentiates α7 ACh receptor responses through indirect activation of CaMKII. Lipids. vol 47. issue 9. 2013-01-21. PMID:22820984. |
in the in situ camkii assay using cultured rat hippocampal neurons, huhs2002 activated camkii and the activation was abolished by kn-93. |
2013-01-21 |
2023-08-12 |
rat |
| Gen-sheng Zhang, Wei-feng Ye, Rong-rong Tao, Ying-mei Lu, Guo-fang Shen, Kohji Fukunaga, Ji-yun Huang, Yue-long Ji, Feng Ha. Expression profiling of Ca(2+)/calmodulin-dependent signaling molecules in the rat dorsal and ventral hippocampus after acute lead exposure. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. vol 64. issue 6. 2012-12-14. PMID:21195594. |
our data demonstrate that nnos expression is significantly higher in the ventral region of the hippocampus when compared to the dorsal region, whereas phosphorylation of camkii (thr286) is less pronounced in the ventral portion of the hippocampus and more pronounced in dorsal regions after acute pb(2+) exposure. |
2012-12-14 |
2023-08-12 |
rat |
| Shahid Khan, Thomas S Reese, Nasir Rajpoot, Ayisha Shabbi. Spatiotemporal maps of CaMKII in dendritic spines. Journal of computational neuroscience. vol 33. issue 1. 2012-12-07. PMID:22218920. |
photo-activatable gfp (pagfp) - camkii fusions were used to map camkii movements between and within spines in dissociated hippocampal neurons. |
2012-12-07 |
2023-08-12 |
Not clear |
| Bettina Buchthal, David Lau, Ursula Weiss, Jan-Marek Weislogel, Hilmar Badin. Nuclear calcium signaling controls methyl-CpG-binding protein 2 (MeCP2) phosphorylation on serine 421 following synaptic activity. The Journal of biological chemistry. vol 287. issue 37. 2012-11-19. PMID:22822052. |
cam kinase ii (camkii) but not camkiv, the major nuclear cam kinase in hippocampal neurons, appeared to mediate this phosphorylation event. |
2012-11-19 |
2023-08-12 |
Not clear |
| Bettina Buchthal, David Lau, Ursula Weiss, Jan-Marek Weislogel, Hilmar Badin. Nuclear calcium signaling controls methyl-CpG-binding protein 2 (MeCP2) phosphorylation on serine 421 following synaptic activity. The Journal of biological chemistry. vol 287. issue 37. 2012-11-19. PMID:22822052. |
camkiiα, -β, -γ, and -δ) are expressed in the cytosol but are also detectable in the cell nucleus of hippocampal neurons, suggesting that nuclear camkii catalyzes mecp2 serine 421 phosphorylation. |
2012-11-19 |
2023-08-12 |
Not clear |
| Yoshinori Kanatsu, Nai Hong Chen, Junya Mitoma, Tetsuto Nakagawa, Yoshio Hirabayashi, Hideyoshi Higash. Gangliosides stimulate bradykinin B2 receptors to promote calmodulin kinase II-mediated neuronal differentiation. Journal of biochemistry. vol 152. issue 1. 2012-11-05. PMID:22577166. |
the b2 antagonist hoe140 inhibited ganglioside-induced camkii activation, actin reorganization and early development of axon- and dendrite-like processes of primary cultured hippocampal neurons. |
2012-11-05 |
2023-08-12 |
Not clear |
| Zhiliang Xu, Suzhen Dong, Dan Du, Nan Jiang, Peiqua Sun, Huikun Wang, Liang Yin, Xuliang Zhang, Xiaohua Cao, Xuechu Zhen, Yinghe H. Generation and characterization of hD5 and C-terminal Mutant hD(5m) transgenic rats. Brain research. vol 1448. 2012-08-20. PMID:22386496. |
the transgenes were driven by the camkii promoter that led the expression mainly in the cerebral cortex and hippocampus. |
2012-08-20 |
2023-08-12 |
human |
| Bihua Feng, Sridhar Raghavachari, John Lisma. Quantitative estimates of the cytoplasmic, PSD, and NMDAR-bound pools of CaMKII in dendritic spines. Brain research. vol 1419. 2012-08-03. PMID:21925648. |
a cytoplasmic concentration of 16 μm (~2590 holoenzymes) in the spine can be estimated from the total measured camkii content of hippocampal tissue, the relative volume of different compartments, and the spine-dendrite ratio of camkii (2:1). |
2012-08-03 |
2023-08-12 |
human |
| Phillip R Zoladz, Collin R Park, Joshua D Halonen, Samina Salim, Karem H Alzoubi, Marisa Srivareerat, Monika Fleshner, Karim A Alkadhi, David M Diamon. Differential expression of molecular markers of synaptic plasticity in the hippocampus, prefrontal cortex, and amygdala in response to spatial learning, predator exposure, and stress-induced amnesia. Hippocampus. vol 22. issue 3. 2012-07-23. PMID:21538655. |
we have studied the effects of spatial learning and predator stress-induced amnesia on the expression of calcium/calmodulin-dependent protein kinase ii (camkii), brain-derived neurotrophic factor (bdnf) and calcineurin in the hippocampus, basolateral amygdala (bla), and medial prefrontal cortex (mpfc). |
2012-07-23 |
2023-08-12 |
rat |
| Dong Hoon Oh, Byung Woo Kim, Miyeon Choi, Garim Lee, June-Seek Choi, Hyeon So. Changes in vascular endothelial growth factor (VEGF) induced by the Morris water maze task. Molecules and cells. vol 33. issue 3. 2012-07-13. PMID:22286233. |
mimicking increases in neuronal vegf in the hippocampus by direct infusion of vegf into ca1 resulted in up-regulation of the phosphorylation of the camp response element-binding (creb) protein and the ca2+/calmodulin-dependent protein kinases ii (camkii). |
2012-07-13 |
2023-08-12 |
rat |
| B-S Kim, M-Y Kim, Y-H Lee. Hippocampal neuronal death induced by kainic acid and restraint stress is suppressed by exercise. Neuroscience. vol 194. 2012-06-25. PMID:21722713. |
prior chronic exercise suppressed ka-induced hippocampal neuronal death in hippocampal ca3 region in restrained mice via declined ros levels, which was lower mda and nitrite levels, and activation of creb, which was mediated by erk1/2 and camkii, suggesting that chronic exercise exerts a protective effect on excitatory neurodegenerative disorders including epileptic seizure. |
2012-06-25 |
2023-08-12 |
mouse |
| Zhi'an Liu, Jing Xu, Xiaojun Shen, Chun'e Lv, Tiejun Xu, Dongsheng Pe. CaMKII antisense oligodeoxynucleotides protect against ischemia-induced neuronal death in the rat hippocampus. Journal of the neurological sciences. vol 314. issue 1-2. 2012-06-04. PMID:22036300. |
camkii antisense oligodeoxynucleotides protect against ischemia-induced neuronal death in the rat hippocampus. |
2012-06-04 |
2023-08-12 |
rat |
| Zhi'an Liu, Jing Xu, Xiaojun Shen, Chun'e Lv, Tiejun Xu, Dongsheng Pe. CaMKII antisense oligodeoxynucleotides protect against ischemia-induced neuronal death in the rat hippocampus. Journal of the neurological sciences. vol 314. issue 1-2. 2012-06-04. PMID:22036300. |
a further aim was to determine the neuroprotective mechanism of camkii antisense odns against ischemia-reperfusion (i/r)-induced neuronal death in the rat hippocampus. |
2012-06-04 |
2023-08-12 |
rat |
| Shigeki Moriguchi, Norifumi Shioda, Yui Yamamoto, Hideaki Tagashira, Kohji Fukunag. The T-type voltage-gated calcium channel as a molecular target of the novel cognitive enhancer ST101: enhancement of long-term potentiation and CaMKII autophosphorylation in rat cortical slices. Journal of neurochemistry. vol 121. issue 1. 2012-05-03. PMID:22251222. |
st101 treatment had a moderate effect on camkii autophosphorylation but no effect on hippocampal protein kinase cα autophosphorylation in slice preparations. |
2012-05-03 |
2023-08-12 |
human |
| Takeshi Kanno, Takahiro Yaguchi, Tetsu Nagata, Tadashi Shimizu, Akito Tanaka, Tomoyuki Nishizak. Indomethacin enhances learning and memory potential by interacting with CaMKII. Journal of cellular physiology. vol 227. issue 3. 2012-04-25. PMID:21503887. |
im activated ca(2+) /calmodulin-dependent protein kinase ii (camkii) in cultured rat hippocampal neurons. |
2012-04-25 |
2023-08-12 |
mouse |
| Takeshi Kanno, Takahiro Yaguchi, Tetsu Nagata, Tadashi Shimizu, Akito Tanaka, Tomoyuki Nishizak. Indomethacin enhances learning and memory potential by interacting with CaMKII. Journal of cellular physiology. vol 227. issue 3. 2012-04-25. PMID:21503887. |
the results of the present study indicate that im could enhance learning and memory potential by facilitating hippocampal synaptic transmission as a result from stimulating presynaptic glutamate release under the control of camkii. |
2012-04-25 |
2023-08-12 |
mouse |
| Jian Hai, Fei Yu, Qi Lin, Shao-Hua S. The changes of signal transduction pathways in hippocampal regions and postsynaptic densities after chronic cerebral hypoperfusion in rats. Brain research. vol 1429. 2012-03-20. PMID:22063366. |
by western blotting, the model rats exhibited significant decrease in the levels of hippocampal ca(2+)-calmodulin-dependent protein kinase ii (camkii), phospho-camkii (p-camkii), phospho-extracellular regulated kinase (p-erk), psd camkii and p-erk, with no corresponding changes in the levels of phosphorylation/dephoosphorylation protein kinase a (pka) and protein kinase c (pkc). |
2012-03-20 |
2023-08-12 |
rat |
| Nikolai Otmakhov, John Lisma. Measuring CaMKII concentration in dendritic spines. Journal of neuroscience methods. vol 203. issue 1. 2012-03-08. PMID:21985762. |
considering the 3:1 ratio of α to β camkii subunits in the hippocampus, the concentrations of total (α+β) camkii subunits in these compartments are 94, 61, and 138 μm, respectively. |
2012-03-08 |
2023-08-12 |
Not clear |
| Shigeki Moriguchi, Yasushi Yabuki, Kohji Fukunag. Reduced calcium/calmodulin-dependent protein kinase II activity in the hippocampus is associated with impaired cognitive function in MPTP-treated mice. Journal of neurochemistry. vol 120. issue 4. 2012-03-08. PMID:22136399. |
taken together, decreased camkii activity with concomitant impaired ltp induction in the hippocampus likely account for the learning disability observed in mptp-treated mice. |
2012-03-08 |
2023-08-12 |
mouse |
| Elek Molná. Long-term potentiation in cultured hippocampal neurons. Seminars in cell & developmental biology. vol 22. issue 5. 2012-01-26. PMID:21807105. |
for example, ltp in dissociated hippocampal neuronal cultures is also dependent on ca(2+) influx through post-synaptic nmda receptors, subsequent activation and autophosphorylation of the ca(2+)/calmodulin-dependent protein kinase ii (camkii) and an increase in alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (ampa) receptor insertion at the post-synaptic membrane. |
2012-01-26 |
2023-08-12 |
Not clear |