| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Julien Bensalem, Laure Servant, Serge Alfos, David Gaudout, Sophie Layé, Véronique Pallet, Pauline Lafenetr. Dietary Polyphenol Supplementation Prevents Alterations of Spatial Navigation in Middle-Aged Mice. Frontiers in behavioral neuroscience. vol 10. 2016-02-23. PMID:26903826. |
these behavioral results were associated with neurobiological changes: while the expression of hippocampal calmodulin kinase ii (camkii) mrna levels was reduced in middle-aged animals, the polyphenol-enriched diet could rescue them. |
2016-02-23 |
2023-08-13 |
mouse |
| Nikolai Otmakhov, Elena V Gorbacheva, Shaurav Regmi, Ryohei Yasuda, Andy Hudmon, John Lisma. Excitotoxic insult results in a long-lasting activation of CaMKIIα and mitochondrial damage in living hippocampal neurons. PloS one. vol 10. issue 3. 2016-02-16. PMID:25793533. |
to complement the biochemical data, we monitored camkii activation in living hippocampal neurons in slice cultures using high spatial/temporal resolution two-photon imaging of the camkiiα fret sensor, camui. |
2016-02-16 |
2023-08-13 |
Not clear |
| Kelsey Barcomb, Dayton J Goodell, Don B Arnold, K Ulrich Baye. Live imaging of endogenous Ca²⁺/calmodulin-dependent protein kinase II in neurons reveals that ischemia-related aggregation does not require kinase activity. Journal of neurochemistry. vol 135. issue 4. 2016-02-16. PMID:26212614. |
within rat hippocampal neurons, an intra-body enabled live monitoring of endogenous camkii aggregation. |
2016-02-16 |
2023-08-13 |
rat |
| Jinzhong Jeremy Goh, Denise Manahan-Vaugha. Role of inhibitory autophosphorylation of calcium/calmodulin-dependent kinase II (αCAMKII) in persistent (>24 h) hippocampal LTP and in LTD facilitated by novel object-place learning and recognition in mice. Behavioural brain research. vol 285. 2015-12-14. PMID:24480420. |
calmodulin-dependent kinase ii (camkii) is strongly expressed in synapses and has been shown to be required for hippocampal ltp in vitro and for spatial learning in the water maze. |
2015-12-14 |
2023-08-12 |
mouse |
| Ikram Ullah, Haroon Badshah, Muhammad Imran Naseer, Hae Young Lee, Myeong Ok Ki. Thymoquinone and vitamin C attenuates pentylenetetrazole-induced seizures via activation of GABAB1 receptor in adult rats cortex and hippocampus. Neuromolecular medicine. vol 17. issue 1. 2015-12-09. PMID:25429759. |
epileptic seizures caused a decline in expression of gamma-aminobutyric acid b1 receptor (gabab1r) (p > 0.05), unchanged expression of protein kinase a (pka), decreased calcium/calmodulin-dependent protein kinase ii (camkii) (p > 0.05) and inhibit the phosphorylation of camp response element-binding protein (creb) (p > 0.05) in cortex and hippocampus, respectively, compared with control. |
2015-12-09 |
2023-08-13 |
rat |
| Maryam Farahmandfar, Mehdi Kadivar, Nasser Naghd. Possible interaction of hippocampal nitric oxide and calcium/calmodulin-dependent protein kinase II on reversal of spatial memory impairment induced by morphine. European journal of pharmacology. vol 751. 2015-12-01. PMID:25661847. |
the aim of the present study was to investigate the role of hippocampal nitric oxide and calcium/calmodulin-dependent protein kinase ii (camkii) on the morphine-induced modulation of spatial memory consolidation in male rats. |
2015-12-01 |
2023-08-13 |
rat |
| Maryam Farahmandfar, Mehdi Kadivar, Nasser Naghd. Possible interaction of hippocampal nitric oxide and calcium/calmodulin-dependent protein kinase II on reversal of spatial memory impairment induced by morphine. European journal of pharmacology. vol 751. 2015-12-01. PMID:25661847. |
we also showed that co-administration of l-arginine (9 µg/rat) and morphine (10 mg/kg) significantly increased camkii activity in the rat hippocampus. |
2015-12-01 |
2023-08-13 |
rat |
| Maryam Farahmandfar, Mehdi Kadivar, Nasser Naghd. Possible interaction of hippocampal nitric oxide and calcium/calmodulin-dependent protein kinase II on reversal of spatial memory impairment induced by morphine. European journal of pharmacology. vol 751. 2015-12-01. PMID:25661847. |
these results indicate that acute single exposure to morphine can modulate consolidation of spatial memory, which may be mediated by a hippocampal nitrergic system and camkii activity. |
2015-12-01 |
2023-08-13 |
rat |
| Shu-Qiu Wang, Xiao-Jie Li, Hong-Bin Qiu, Zhi-Mei Jiang, Maria Simon, Xiao-Ru Ma, Lei Liu, Jun-Xing Liu, Fang-Fang Wang, Yan-Feng Liang, Jia-Mei Wu, Wei-Hua Di, Shaobo Zho. Anti-epileptic effect of Ganoderma lucidum polysaccharides by inhibition of intracellular calcium accumulation and stimulation of expression of CaMKII α in epileptic hippocampal neurons. PloS one. vol 9. issue 7. 2015-11-10. PMID:25010576. |
anti-epileptic effect of ganoderma lucidum polysaccharides by inhibition of intracellular calcium accumulation and stimulation of expression of camkii α in epileptic hippocampal neurons. |
2015-11-10 |
2023-08-13 |
Not clear |
| Sonja Buratovic, Bo Stenerlöw, Anders Fredriksson, Synnöve Sundell-Bergman, Henrik Viberg, Per Eriksso. Neonatal exposure to a moderate dose of ionizing radiation causes behavioural defects and altered levels of tau protein in mice. Neurotoxicology. vol 45. 2015-10-13. PMID:25265567. |
the neuroproteins camkii, gap-43, synaptophysin and total tau in male mouse cerebral cortex and hippocampus were analysed 24h post-irradiation and in adults at 6 months of age exposed to 0 or 500 mgy on pnd 10. |
2015-10-13 |
2023-08-13 |
mouse |
| Xia Jiang, Gao-Shang Chai, Zhi-Hao Wang, Yu Hu, Xiao-Guang Li, Zhi-Wei Ma, Qun Wang, Jian-Zhi Wang, Gong-Ping Li. CaMKII-dependent dendrite ramification and spine generation promote spatial training-induced memory improvement in a rat model of sporadic Alzheimer's disease. Neurobiology of aging. vol 36. issue 2. 2015-09-17. PMID:25457025. |
spatial training also increased the levels of postsynaptic glua1, glun2a, glun2b, and psd93 with selective activation of calcium/calmodulin-dependent protein kinase ii (camkii), although inhibition of camkii by stereotaxic injection of kn93 into hippocampal dg, abolished the training-induced cognitive improvement, dendrite ramification, and spine generation. |
2015-09-17 |
2023-08-13 |
rat |
| Aline Domínguez-Alonso, Marcela Valdés-Tovar, Héctor Solís-Chagoyán, Gloria Benítez-Kin. Melatonin stimulates dendrite formation and complexity in the hilar zone of the rat hippocampus: participation of the Ca++/Calmodulin complex. International journal of molecular sciences. vol 16. issue 1. 2015-09-16. PMID:25603176. |
in this work we investigated whether mel stimulates dendrite formation by camkii activation in organotypic cultures from adult rat hippocampus. |
2015-09-16 |
2023-08-13 |
rat |
| Aline Domínguez-Alonso, Marcela Valdés-Tovar, Héctor Solís-Chagoyán, Gloria Benítez-Kin. Melatonin stimulates dendrite formation and complexity in the hilar zone of the rat hippocampus: participation of the Ca++/Calmodulin complex. International journal of molecular sciences. vol 16. issue 1. 2015-09-16. PMID:25603176. |
we found that the camkii inhibitor, kn-62, abolished the mel stimulatory effects on dendritogenesis and that mel increased the relative amount of cam in the soluble fraction of hippocampal slices. |
2015-09-16 |
2023-08-13 |
rat |
| Aline Domínguez-Alonso, Marcela Valdés-Tovar, Héctor Solís-Chagoyán, Gloria Benítez-Kin. Melatonin stimulates dendrite formation and complexity in the hilar zone of the rat hippocampus: participation of the Ca++/Calmodulin complex. International journal of molecular sciences. vol 16. issue 1. 2015-09-16. PMID:25603176. |
data strongly suggest that mel could repair the loss of hippocampal dendrites that occur in neuropsychiatric disorders by increasing cam levels and activation of camkii. |
2015-09-16 |
2023-08-13 |
rat |
| A J Robiso. Emerging role of CaMKII in neuropsychiatric disease. Trends in neurosciences. vol 37. issue 11. 2015-09-04. PMID:25087161. |
although it has been known for decades that hippocampal calcium/calmodulin (cam)-dependent protein kinase ii (camkii) plays an essential role in learning and memory consolidation, the roles of camkii in other brain regions are only recently being explored in depth. |
2015-09-04 |
2023-08-13 |
Not clear |
| Shu-Fang Xia, Zhen-Xing Xie, Yi Qiao, Li-Rong Li, Xiang-Rong Cheng, Xue Tang, Yong-Hui Shi, Guo-Wei L. Differential effects of quercetin on hippocampus-dependent learning and memory in mice fed with different diets related with oxidative stress. Physiology & behavior. vol 138. 2015-08-26. PMID:25447470. |
at the end of the study period, fasting blood glucose (fbg), plasma and hippocampal markers of oxidative stress, plasma lipid status, morris water maze as well as hippocampal relative mrna expression of akt, bdnf, camkii, creb, gsk-3β, nrf2 and pi3k were examined. |
2015-08-26 |
2023-08-13 |
mouse |
| Amina Chaalal, Roseline Poirier, David Blum, Brigitte Gillet, Pascale Le Blanc, Marie Basquin, Luc Buée, Serge Laroche, Valérie Enderli. PTU-induced hypothyroidism in rats leads to several early neuropathological signs of Alzheimer's disease in the hippocampus and spatial memory impairments. Hippocampus. vol 24. issue 11. 2015-07-07. PMID:24978200. |
these modifications were associated with impaired spatial memory and reduced hippocampal expression of signaling molecules important for synaptic plasticity and memory, including neurogranin, camkii, erk, gsk3β, creb, and expression of the transcription factor egr1/zif268. |
2015-07-07 |
2023-08-13 |
rat |
| Liang Chen, Yanyan Miao, Lin Chen, Jing Xu, Xinxing Wang, Han Zhao, Yi Shen, Yi Hu, Yunpeng Bian, Yuanyuan Shen, Jutao Chen, Yingying Zha, Long-Ping Wen, Ming Wan. The role of low levels of fullerene C60 nanocrystals on enhanced learning and memory of rats through persistent CaMKII activation. Biomaterials. vol 35. issue 34. 2015-05-12. PMID:25129570. |
fullerene nanoparticles have been reported to specifically bind to and elicit persistent activation of hippocampal ca(2+)/calmodulin-dependent protein kinase ii (camkii), a multimeric intracellular serine/threonine kinase central to ca(2+) signal transduction and critical for synaptic plasticity, but the functional consequence of that modulation is unknown. |
2015-05-12 |
2023-08-13 |
rat |
| Marie-Elaine Laurier-Laurin, Audrée De Montigny, Suzanne Attiori Essis, Michel Cyr, Guy Massicott. Blockade of lysosomal acid ceramidase induces GluN2B-dependent Tau phosphorylation in rat hippocampal slices. Neural plasticity. vol 2014. 2015-05-11. PMID:25276436. |
on the other hand, preincubation of hippocampal slices with the compound kn-62, an inhibitor known to interfere with calcium/calmodulin-dependent protein kinase ii (camkii), totally abolished the effect of aci on tau phosphorylation at ser262 epitopes. |
2015-05-11 |
2023-08-13 |
rat |
| Marie-Elaine Laurier-Laurin, Audrée De Montigny, Suzanne Attiori Essis, Michel Cyr, Guy Massicott. Blockade of lysosomal acid ceramidase induces GluN2B-dependent Tau phosphorylation in rat hippocampal slices. Neural plasticity. vol 2014. 2015-05-11. PMID:25276436. |
collectively, these results provide experimental evidence that ceramides play an important role in regulating tau phosphorylation in the hippocampus via a mechanism dependent on glun2b receptor subunits and camkii activation. |
2015-05-11 |
2023-08-13 |
rat |