| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fernando J Bustos, Nur Jury, Pablo Martinez, Estibaliz Ampuero, Matias Campos, Sebastian Abarzúa, Karen Jaramillo, Susanne Ibing, Muriel D Mardones, Henny Haensgen, Julia Kzhyshkowska, Maria Florencia Tevy, Rachael Neve, Magdalena Sanhueza, Lorena Varela-Nallar, Martín Montecino, Brigitte van Zunder. NMDA receptor subunit composition controls dendritogenesis of hippocampal neurons through CAMKII, CREB-P, and H3K27ac. Journal of cellular physiology. vol 232. issue 12. 2017-10-02. PMID:28160495. |
here, we found that dendritogenesis in hippocampal neurons is impaired by several well-characterized constructs (i.e., nr2b-rs/qd) and peptides (i.e., tatcn21) that specifically interfere with the recruitment and interaction of camkii with the nr2b c-terminal domain. |
2017-10-02 |
2023-08-13 |
Not clear |
| Fernando J Bustos, Nur Jury, Pablo Martinez, Estibaliz Ampuero, Matias Campos, Sebastian Abarzúa, Karen Jaramillo, Susanne Ibing, Muriel D Mardones, Henny Haensgen, Julia Kzhyshkowska, Maria Florencia Tevy, Rachael Neve, Magdalena Sanhueza, Lorena Varela-Nallar, Martín Montecino, Brigitte van Zunder. NMDA receptor subunit composition controls dendritogenesis of hippocampal neurons through CAMKII, CREB-P, and H3K27ac. Journal of cellular physiology. vol 232. issue 12. 2017-10-02. PMID:28160495. |
interestingly, we found that transduction of nr2aΔin, a mutant nr2a construct with increased interaction to camkii, reactivates dendritogenesis in mature hippocampal neurons in vitro and in vivo. |
2017-10-02 |
2023-08-13 |
Not clear |
| Kohji Fukunaga, Shigeki Moriguch. Stimulation of the Sigma-1 Receptor and the Effects on Neurogenesis and Depressive Behaviors in Mice. Advances in experimental medicine and biology. vol 964. 2017-09-26. PMID:28315273. |
sig-1r stimulation also enhances camkii /camkiv and protein kinase b (akt) activities in hippocampus. |
2017-09-26 |
2023-08-13 |
mouse |
| Peng Wang, Yonggang Cao, Juan Yu, Ruxia Liu, Bing Bai, Hanping Qi, Qianlong Zhang, Wenguang Guo, Hui Zhu, Lihui Q. Baicalin alleviates ischemia-induced memory impairment by inhibiting the phosphorylation of CaMKII in hippocampus. Brain research. vol 1642. 2017-05-22. PMID:27016057. |
baicalin alleviates ischemia-induced memory impairment by inhibiting the phosphorylation of camkii in hippocampus. |
2017-05-22 |
2023-08-13 |
Not clear |
| Peng Wang, Yonggang Cao, Juan Yu, Ruxia Liu, Bing Bai, Hanping Qi, Qianlong Zhang, Wenguang Guo, Hui Zhu, Lihui Q. Baicalin alleviates ischemia-induced memory impairment by inhibiting the phosphorylation of CaMKII in hippocampus. Brain research. vol 1642. 2017-05-22. PMID:27016057. |
western blotting analysis indicated that baicalin suppressed ischemia-caused elevated phosphorylation level of camkii in vivo, in hippocampal neurons in culture, and in sh-sy5y cells in culture. |
2017-05-22 |
2023-08-13 |
Not clear |
| Peng Wang, Yonggang Cao, Juan Yu, Ruxia Liu, Bing Bai, Hanping Qi, Qianlong Zhang, Wenguang Guo, Hui Zhu, Lihui Q. Baicalin alleviates ischemia-induced memory impairment by inhibiting the phosphorylation of CaMKII in hippocampus. Brain research. vol 1642. 2017-05-22. PMID:27016057. |
we found that baicalin, a camkii inhibitor and knocking down the camkii prevented ogd-induced apoptosis of hippocampal or sh-sy5y cells in culture. |
2017-05-22 |
2023-08-13 |
Not clear |
| Peng Wang, Yonggang Cao, Juan Yu, Ruxia Liu, Bing Bai, Hanping Qi, Qianlong Zhang, Wenguang Guo, Hui Zhu, Lihui Q. Baicalin alleviates ischemia-induced memory impairment by inhibiting the phosphorylation of CaMKII in hippocampus. Brain research. vol 1642. 2017-05-22. PMID:27016057. |
therefore, these results suggested that baicalin improves learning and memory impairment induced by global cerebral ischemia/reperfusion in gerbils via attenuating the phosphorylation level of camkii and further preventing hippocampal neuronal apoptosis. |
2017-05-22 |
2023-08-13 |
Not clear |
| Ayse Dosemeci, Dana Toy, Amelia Burch, K Ulrich Bayer, Jung-Hwa Tao-Chen. CaMKII-mediated displacement of AIDA-1 out of the postsynaptic density core. FEBS letters. vol 590. issue 17. 2017-05-05. PMID:27477489. |
immuno-electron microscopy studies show that treatment of hippocampal neurons with nmda results in an ~ 30 nm shift in the median distance of the aida-1 label from the postsynaptic membrane, an effect that is blocked by the camkii inhibitor tatcn21. |
2017-05-05 |
2023-08-13 |
Not clear |
| Tao Chen, Yuan-Jian Yang, Yan-Kun Li, Jing Liu, Peng-Fei Wu, Fang Wang, Jian-Guo Chen, Li-Hong Lon. Chronic administration tetrahydroxystilbene glucoside promotes hippocampal memory and synaptic plasticity and activates ERKs, CaMKII and SIRT1/miR-134 in vivo. Journal of ethnopharmacology. vol 190. 2017-04-18. PMID:27275773. |
chronic administration tetrahydroxystilbene glucoside promotes hippocampal memory and synaptic plasticity and activates erks, camkii and sirt1/mir-134 in vivo. |
2017-04-18 |
2023-08-13 |
Not clear |
| Yasushi Yabuki, Kazuya Matsuo, Koga Hirano, Yasuharu Shinoda, Shigeki Moriguchi, Kohji Fukunag. Combined Memantine and Donepezil Treatment Improves Behavioral and Psychological Symptoms of Dementia-Like Behaviors in Olfactory Bulbectomized Mice. Pharmacology. vol 99. issue 3-4. 2017-03-17. PMID:28049192. |
these results suggest that improvement of bpsd-like behaviors by the co-administration of both drugs is in part mediated by enhanced 5-ht release and camkii activity in obx mouse hippocampus. |
2017-03-17 |
2023-08-13 |
mouse |
| Shuo Li, Jing Han, Dong-Sheng Wang, Bin Feng, Ya-Ting Deng, Xin-Shang Wang, Qi Yang, Ming-Gao Zha. Echinocystic acid reduces reserpine-induced pain/depression dyad in mice. Metabolic brain disease. vol 31. issue 2. 2017-01-10. PMID:26729203. |
at the same time, the increase in glun2b-containing nmda receptors, p-glua1-ser831, psd-95 and camkii were integrated with the increase in caspase-3 and inos levels in the hippocampus of the reserpine-injected mice. |
2017-01-10 |
2023-08-13 |
mouse |
| Ankang Hu, Honghua Yuan, Lianlian Wu, Renjin Chen, Quangang Chen, Tengye Zhang, Zhenzhen Wang, Peng Liu, Xiaorong Zh. The effect of constitutive over-expression of insulin-like growth factor 1 on the cognitive function in aged mice. Brain research. vol 1631. 2016-12-13. PMID:26581336. |
accordingly, our findings indicated that igf-1 may mitigate the aged-associated cognitive decline via promoting neurogenesis in the hippocampus and activating camkii and erk signaling by binding with igf-1r. |
2016-12-13 |
2023-08-13 |
mouse |
| Kia J Jackson, Pretal P Muldoon, Carrie Walters, Mohamad Imad Dama. Neuronal calcium/calmodulin-dependent protein kinase II mediates nicotine reward in the conditioned place preference test in mice. Behavioural pharmacology. vol 27. issue 1. 2016-09-19. PMID:26292186. |
further, we assessed camkii activity in the ventral tegmental area (vta), nucleus accumbens (nac), prefrontal cortex, and hippocampus after nicotine cpp and found significant increases in camkii activity in the mouse vta and nac that were blocked by camkii antagonists. |
2016-09-19 |
2023-08-13 |
mouse |
| Anne Létondor, Benjamin Buaud, Carole Vaysse, Emmanuel Richard, Sophie Layé, Véronique Pallet, Serge Alfo. EPA/DHA and Vitamin A Supplementation Improves Spatial Memory and Alleviates the Age-related Decrease in Hippocampal RXRγ and Kinase Expression in Rats. Frontiers in aging neuroscience. vol 8. 2016-05-31. PMID:27242514. |
rarα, rxrβ, and rxrγ mrna expression and camkii, akt, erk1/2 expression were decreased in the hippocampus of middle-aged rats. |
2016-05-31 |
2023-08-13 |
rat |
| Anne Létondor, Benjamin Buaud, Carole Vaysse, Emmanuel Richard, Sophie Layé, Véronique Pallet, Serge Alfo. EPA/DHA and Vitamin A Supplementation Improves Spatial Memory and Alleviates the Age-related Decrease in Hippocampal RXRγ and Kinase Expression in Rats. Frontiers in aging neuroscience. vol 8. 2016-05-31. PMID:27242514. |
a combined epa/dha and vitamin a supplementation had a beneficial additive effect on reference memory but not in working memory in middle-aged rats, associated with an alleviation of the age-related decrease in rxrγ, camkii, akt, and erk1 expression in the hippocampus. |
2016-05-31 |
2023-08-13 |
rat |
| Yu Chen, Zhuoyi Liang, Erkang Fei, Yuewen Chen, Xiaopu Zhou, Weiqun Fang, Wing-Yu Fu, Amy K Y Fu, Nancy Y I. Axin Regulates Dendritic Spine Morphogenesis through Cdc42-Dependent Signaling. PloS one. vol 10. issue 7. 2016-05-02. PMID:26204446. |
here, we report that axin protein is enriched in synaptic fractions, colocalizes with the postsynaptic marker psd-95 in cultured hippocampal neurons, and interacts with a signaling protein ca(2+)/calmodulin-dependent protein kinase ii (camkii) in synaptosomal fractions. |
2016-05-02 |
2023-08-13 |
Not clear |
| Xia Jiang, Gao-Shang Chai, Zhi-Hao Wang, Yu Hu, Xiao-Guang Li, Zhi-Wei Ma, Qun Wang, Jian-Zhi Wang, Gong-Ping Li. Spatial training preserves associative memory capacity with augmentation of dendrite ramification and spine generation in Tg2576 mice. Scientific reports. vol 5. 2016-04-05. PMID:25820815. |
in the molecular level, the mwm training remarkably activated calcium/calmodulin-dependent protein kinase ii (camkii) with elevation of glutamate ampa receptor glua1 subunit (glua1), postsynaptic density protein 93 (psd93) and postsynaptic density protein 95 (psd95) in the hippocampus. |
2016-04-05 |
2023-08-13 |
mouse |
| Soe Thein, Jung-Hwa Tao-Cheng, Yan Li, K Ulrich Bayer, Thomas S Reese, Ayse Dosemec. CaMKII mediates recruitment and activation of the deubiquitinase CYLD at the postsynaptic density. PloS one. vol 9. issue 3. 2016-03-31. PMID:24614225. |
nmda treatment of cultured hippocampal neurons causes recruitment of cyld, as well as camkii, to the postsynaptic density (psd), as shown by immunoelectron microscopy. |
2016-03-31 |
2023-08-12 |
human |
| Andras Kern, Maria Mavrikaki, Celine Ullrich, Rosie Albarran-Zeckler, Alicia Faruzzi Brantley, Roy G Smit. Hippocampal Dopamine/DRD1 Signaling Dependent on the Ghrelin Receptor. Cell. vol 163. issue 5. 2016-03-27. PMID:26590421. |
activation by a drd1 agonist produced non-canonical signal transduction via gαq-plc-ip3-ca(2+) at the expense of canonical drd1 gαs camp signaling to result in camkii activation, glutamate receptor exocytosis, synaptic reorganization, and expression of early markers of hippocampal synaptic plasticity. |
2016-03-27 |
2023-08-13 |
mouse |
| Younghwan Lee, Qingtao Gao, Eunji Kim, Younghwa Lee, Se Jin Park, Hyung Eun Lee, Dae Sik Jang, Jong Hoon Ry. Pretreatment with 5-hydroxymethyl-2-furaldehyde blocks scopolamine-induced learning deficit in contextual and spatial memory in male mice. Pharmacology, biochemistry, and behavior. vol 134. 2016-03-23. PMID:25922228. |
furthermore, western blot analysis revealed that the levels of phosphorylated ca(2+)/calmodulin-dependent protein kinase ii-α (camkii) and extracellular signal-regulated kinases (erk) were significantly enhanced by the single administration of 5-hmf in the hippocampal tissues. |
2016-03-23 |
2023-08-13 |
mouse |