| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y Chaput, C de Montign. Effects of the 5-hydroxytryptamine receptor antagonist, BMY 7378, on 5-hydroxytryptamine neurotransmission: electrophysiological studies in the rat central nervous system. The Journal of pharmacology and experimental therapeutics. vol 246. issue 1. 1988-08-17. PMID:2839669. |
in the present electrophysiological studies, the effects of the putative 5-hydroxytryptamine (5-ht) receptor antagonist, bmy 7378, on the response of dorsal raphe nucleus 5-ht neurons and of ca3 dorsal hippocampus pyramidal neurons to 5-ht and 8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat) were investigated in chloral hydrate-anesthetized rats. |
1988-08-17 |
2023-08-11 |
rat |
| K A Cunningham, J M Lakosk. Electrophysiological effects of cocaine and procaine on dorsal raphe serotonin neurons. European journal of pharmacology. vol 148. issue 3. 1988-08-11. PMID:3384007. |
electrophysiological effects of cocaine and procaine on dorsal raphe serotonin neurons. |
1988-08-11 |
2023-08-11 |
rat |
| K A Cunningham, J M Lakosk. Electrophysiological effects of cocaine and procaine on dorsal raphe serotonin neurons. European journal of pharmacology. vol 148. issue 3. 1988-08-11. PMID:3384007. |
the effects of cocaine and procaine on the spontaneous activity of serotonin (5-hydroxytryptamine, 5-ht) neurons in the dorsal raphe nucleus of the chloral hydrate anesthetized male rat were characterized using extracellular single-unit and microiontophoretic recording techniques. |
1988-08-11 |
2023-08-11 |
rat |
| K A Cunningham, J M Lakosk. Electrophysiological effects of cocaine and procaine on dorsal raphe serotonin neurons. European journal of pharmacology. vol 148. issue 3. 1988-08-11. PMID:3384007. |
microiontophoretic application of cocaine, but not procaine, also depressed spontaneous cell firing of 5-ht-containing neurons and potentiated the inhibitory effects of 5-ht in the dorsal raphe nucleus. |
1988-08-11 |
2023-08-11 |
rat |
| M Geffard, S Tuffet, N Mons, J L Chagnau. Simultaneous detection of indoleamines and dopamine in rat dorsal raphe nuclei using specific antibodies. Histochemistry. vol 88. issue 1. 1988-04-07. PMID:2449405. |
using a monoclonal antibody against dopamine and a rabbit antiserum against serotonin, 5-methoxytryptamine or tryptamine, we were able to achieve the simultaneous localization of two amines in glutaraldehyde-fixed sections of rat dorsal raphe nuclei. |
1988-04-07 |
2023-08-11 |
rat |
| K Semba, P B Reiner, E G McGeer, H C Fibige. Brainstem afferents to the magnocellular basal forebrain studied by axonal transport, immunohistochemistry, and electrophysiology in the rat. The Journal of comparative neurology. vol 267. issue 3. 1988-03-28. PMID:2449477. |
in the dorsal raphe nucleus, some retrogradely labelled neurons were positive for serotonin and some for tyrosine hydroxylase (th); however, the majority of retrogradely labelled neurons in this region were not immunoreactive for either marker. |
1988-03-28 |
2023-08-11 |
rat |
| C T Fischette, B Nock, K Renne. Effects of 5,7-dihydroxytryptamine on serotonin1 and serotonin2 receptors throughout the rat central nervous system using quantitative autoradiography. Brain research. vol 421. issue 1-2. 1988-02-10. PMID:3690273. |
the results indicate that at least some of the 5-ht1 sites labelled by [3h]5-ht in the hippocampus and dorsal raphe nucleus are presynaptic, whereas 5-ht2 receptors are probably postsynaptic. |
1988-02-10 |
2023-08-11 |
rat |
| R B Innis, G K Aghajania. Pertussis toxin blocks 5-HT1A and GABAB receptor-mediated inhibition of serotonergic neurons. European journal of pharmacology. vol 143. issue 2. 1988-02-02. PMID:2826189. |
to examine the role of guanine nucleotide binding (g) proteins in receptor-mediated inhibition of serotonin (5-ht) neurons, we intracerebrally injected pertussis toxin (0.5-1.0 microgram) into rat midbrain in a region immediately rostral to the dorsal raphe nucleus. |
1988-02-02 |
2023-08-11 |
rat |
| R B Innis, G K Aghajania. Pertussis toxin blocks 5-HT1A and GABAB receptor-mediated inhibition of serotonergic neurons. European journal of pharmacology. vol 143. issue 2. 1988-02-02. PMID:2826189. |
our data provide strong evidence for the role of a pertussis toxin substrate(s) (presumably a g protein(s] in mediating the inhibition induced by the autoreceptor and gabab receptor on 5-ht neurons in rat dorsal raphe nucleus. |
1988-02-02 |
2023-08-11 |
rat |
| b' V V Raevski\\xc4\\xa. [Formation of serotonin- and GABA-ergic mechanisms of synaptic transmission in the cat neocortex during early ontogenesis]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 37. issue 4. 1987-12-16. PMID:2823502.' |
in acute experiment on 5-20 days kittens, the reactions were studied of neurones in the cortical somatosensory zone to stimulation of the dorsal raphe nucleus (drn) and application of serotonin, ethanolamine-o-sulphate and bicucullin. |
1987-12-16 |
2023-08-11 |
cat |
| G A Marks, S G Speciale, K Cobbey, H P Roffwar. Serotonergic inhibition of the dorsal lateral geniculate nucleus. Brain research. vol 418. issue 1. 1987-12-09. PMID:2444312. |
electrophysiological studies were conducted on chloral hydrate-anesthetized rats to determine if the dorsal raphe nucleus (dr) exerts an inhibitory influence upon the dorsal lateral geniculate nucleus (dlgn), and if this inhibition is mediated by the release of serotonin (5-ht). |
1987-12-09 |
2023-08-11 |
rat |
| A Romaniuk, M Filipczak, J Frycza. The influence of injection of 5,6-dihydroxytryptamine to the dorsal raphe nucleus on carbachol-induced defensive behavior and regional brain amine content in the cat. Polish journal of pharmacology and pharmacy. vol 39. issue 1. 1987-11-25. PMID:2444950. |
the 5,6-dihydroxytryptamine-induced lesions of serotonergic neurons in the dorsal raphe nucleus of the cat resulted in an increase in the carbachol-induced growling response, a decrease in the concentrations of noradrenaline, serotonin and 5-hydroxyindoleacetic acid in the hypothalamus, midbrain and amygdala, and an increase in the hypothalamic dopamine level. |
1987-11-25 |
2023-08-11 |
cat |
| E H Lee, H H Lin, H M Yi. Differential influences of different stressors upon midbrain raphe neurons in rats. Neuroscience letters. vol 80. issue 1. 1987-11-18. PMID:2443877. |
results indicate that shock-induced fighting experience preferentially decreased serotonin (5-ht) levels in the dorsal raphe and striatum, while air puff stimulation selectively lowered 5-ht and 5-hydroxyindoleacetic acid (5-hiaa) contents in the median raphe and hippocampus. |
1987-11-18 |
2023-08-11 |
rat |
| M G De Simoni, G Dal Toso, F Fodritto, A Sokola, S Alger. Modulation of striatal dopamine metabolism by the activity of dorsal raphe serotonergic afferences. Brain research. vol 411. issue 1. 1987-08-28. PMID:2440514. |
serotonin (5-ht)-dopamine (da) interaction was studied in the caudate nucleus after electrical stimulation of the dorsal raphe (dr), an area containing 5-ht cell bodies and sending afferences to nigrostriatal dopaminergic neurons. |
1987-08-28 |
2023-08-11 |
rat |
| L O Wilkinson, E D Abercrombie, K Rasmussen, B L Jacob. Effect of buspirone on single unit activity in locus coeruleus and dorsal raphe nucleus in behaving cats. European journal of pharmacology. vol 136. issue 1. 1987-07-24. PMID:3595712. |
the effects of administration of the non-benzodiazepine anxiolytic buspirone on the spontaneous and sensory evoked single unit activity of serotonergic (5-ht) neurons in the dorsal raphe nucleus and noradrenergic (ne) neurons in the locus coeruleus were examined in freely moving cats. |
1987-07-24 |
2023-08-11 |
Not clear |
| L O Wilkinson, E D Abercrombie, K Rasmussen, B L Jacob. Effect of buspirone on single unit activity in locus coeruleus and dorsal raphe nucleus in behaving cats. European journal of pharmacology. vol 136. issue 1. 1987-07-24. PMID:3595712. |
strongly suppressed both the spontaneous and evoked activity of 5-ht dorsal raphe nucleus neurons. |
1987-07-24 |
2023-08-11 |
Not clear |
| L O Wilkinson, E D Abercrombie, K Rasmussen, B L Jacob. Effect of buspirone on single unit activity in locus coeruleus and dorsal raphe nucleus in behaving cats. European journal of pharmacology. vol 136. issue 1. 1987-07-24. PMID:3595712. |
it is suggested that the anxiolytic effects of buspirone administration are not achieved through an action of ne neurons, but may be mediated in part by actions on 5-ht neurons in the dorsal raphe. |
1987-07-24 |
2023-08-11 |
Not clear |
| E H Lee, F B Wang, Y P Tang, M A Geye. Gabaergic interneurons in the dorsal raphe mediate the effects of apomorphine on serotonergic system. Brain research bulletin. vol 18. issue 3. 1987-07-16. PMID:2438015. |
in examination of the exact anatomical locus of gaba neurons responsible for the observed effects of apo, the results indicate that bilateral lateral habenular lesions did not block the effects of apo on 5-ht neurons, while direct picrotoxin infusion to the dorsal raphe, at a dose having no significant influence by itself, antagonized apo's actions. |
1987-07-16 |
2023-08-11 |
Not clear |
| E H Lee, F B Wang, Y P Tang, M A Geye. Gabaergic interneurons in the dorsal raphe mediate the effects of apomorphine on serotonergic system. Brain research bulletin. vol 18. issue 3. 1987-07-16. PMID:2438015. |
together with the anatomical, biochemical and histofluorescent findings, it is suggested that apo influences dorsal raphe 5-ht by stimulation of da autoreceptors in the substantia nigra; therefore, inhibition of da neuron activity and the nigro-raphe pathway. |
1987-07-16 |
2023-08-11 |
Not clear |
| E H Lee, F B Wang, Y P Tang, M A Geye. Gabaergic interneurons in the dorsal raphe mediate the effects of apomorphine on serotonergic system. Brain research bulletin. vol 18. issue 3. 1987-07-16. PMID:2438015. |
normally, da probably exerts an excitatory influence on gabaergic interneurons in the dorsal raphe, and these inhibitory interneurons then synapse on 5-ht neurons in the same area. |
1987-07-16 |
2023-08-11 |
Not clear |