| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J M Khanna, C Campanelli, A D Lê, H Kalan. Effect of raphe lesions on the development of chronic tolerance to pentobarbital and cross-tolerance to ethanol. Psychopharmacology. vol 91. issue 4. 1987-06-30. PMID:3108927. |
sham and electrolytic lesions of the dorsal, median, and median + dorsal raphe nuclei were made in different groups of rats, and the differential patterns of regional 5-ht depletion were verified chemically. |
1987-06-30 |
2023-08-11 |
rat |
| E H Le. Additive effects of apomorphine and clonidine on serotonin neurons in the dorsal raphe. Life sciences. vol 40. issue 7. 1987-03-26. PMID:2433562. |
additive effects of apomorphine and clonidine on serotonin neurons in the dorsal raphe. |
1987-03-26 |
2023-08-11 |
Not clear |
| E H Le. Additive effects of apomorphine and clonidine on serotonin neurons in the dorsal raphe. Life sciences. vol 40. issue 7. 1987-03-26. PMID:2433562. |
both drugs selectively elevated serotonin (5-ht) concentrations in the dorsal raphe and the striatum without significantly altering 5-ht measures in the median raphe and the hippocampus. |
1987-03-26 |
2023-08-11 |
Not clear |
| E H Le. Additive effects of apomorphine and clonidine on serotonin neurons in the dorsal raphe. Life sciences. vol 40. issue 7. 1987-03-26. PMID:2433562. |
co-administration of apo and clon, at doses of each drug exerted maximum effects on 5-ht alone, produced an additive effect on 5-ht in the dorsal raphe, while their effects on 5-ht and 5-hiaa in the striatum were counteracting each other. |
1987-03-26 |
2023-08-11 |
Not clear |
| E H Le. Additive effects of apomorphine and clonidine on serotonin neurons in the dorsal raphe. Life sciences. vol 40. issue 7. 1987-03-26. PMID:2433562. |
therefore, the present results support the hypothesis that the additive effects of apo and clon on dorsal raphe 5-ht are mediated through different receptors and neuropharmacological mechanisms. |
1987-03-26 |
2023-08-11 |
Not clear |
| H Agren, M Koulu, J M Saavedra, W Z Potter, M Linnoil. Circadian covariation of norepinephrine and serotonin in the locus coeruleus and dorsal raphe nucleus in the rat. Brain research. vol 397. issue 2. 1987-03-18. PMID:3801874. |
circadian covariation of norepinephrine and serotonin in the locus coeruleus and dorsal raphe nucleus in the rat. |
1987-03-18 |
2023-08-11 |
rat |
| H Agren, M Koulu, J M Saavedra, W Z Potter, M Linnoil. Circadian covariation of norepinephrine and serotonin in the locus coeruleus and dorsal raphe nucleus in the rat. Brain research. vol 397. issue 2. 1987-03-18. PMID:3801874. |
we report robust correlations between concentrations of the neurotransmitters norepinephrine and serotonin in the locus coeruleus and the dorsal raphe nucleus of the brainstem in rats analyzed at 7 different time points over 24 h. we found similar circadian rhythmicities for both monoamines with acrophases just before the onset of the dark period. |
1987-03-18 |
2023-08-11 |
rat |
| H Agren, M Koulu, J M Saavedra, W Z Potter, M Linnoil. Circadian covariation of norepinephrine and serotonin in the locus coeruleus and dorsal raphe nucleus in the rat. Brain research. vol 397. issue 2. 1987-03-18. PMID:3801874. |
the monoamine concentrations diminished and the significant intercorrelation between norepinephrine and serotonin in the locus coeruleus disappeared during the night suggestive of a noradrenergic stimulation of dorsal raphe serotonin during the day. |
1987-03-18 |
2023-08-11 |
rat |
| P Blier, C de Montigny, A J Azzar. Effect of repeated amiflamine administration on serotonergic and noradrenergic neurotransmission: electrophysiological studies in the rat CNS. Naunyn-Schmiedeberg's archives of pharmacology. vol 334. issue 3. 1987-03-04. PMID:3808082. |
the firing activity of dorsal raphe 5-ht neurons, but not that of ne neurons, was markedly decreased 2-6 h after the last dose of a 2-day treatment. |
1987-03-04 |
2023-08-11 |
rat |
| J S Sprouse, G K Aghajania. (-)-Propranolol blocks the inhibition of serotonergic dorsal raphe cell firing by 5-HT1A selective agonists. European journal of pharmacology. vol 128. issue 3. 1987-01-27. PMID:2878817. |
the ability of the beta-adrenoceptor antagonist propranolol to block the effects of serotonin (5-ht) and 5-ht1a-selective agonists on the spontaneous firing of serotonergic dorsal raphe neurons was assessed. |
1987-01-27 |
2023-08-11 |
Not clear |
| J S Sprouse, G K Aghajania. (-)-Propranolol blocks the inhibition of serotonergic dorsal raphe cell firing by 5-HT1A selective agonists. European journal of pharmacology. vol 128. issue 3. 1987-01-27. PMID:2878817. |
however, (-)-propranolol was a relatively weak antagonist of 5-ht itself, suggesting that the endogenous neurotransmitter may have actions on dorsal raphe neurons in addition to those mediated by 5-ht1a receptors. |
1987-01-27 |
2023-08-11 |
Not clear |
| A Basse-Tomusk, G V Rebe. Ipsapirone depresses neuronal activity in the dorsal raphe nucleus and the hippocampal formation. European journal of pharmacology. vol 130. issue 1-2. 1987-01-06. PMID:3780856. |
in the hippocampus, dentate granule cells matched the responsiveness of dorsal raphe serotonin neurons, the median effective dose for 50% inhibition being 125.0 micrograms/kg in both areas. |
1987-01-06 |
2023-08-11 |
rat |
| A M Stuart, I J Mitchell, P Slater, H L Unwin, A R Crossma. A semi-quantitative atlas of 5-hydroxytryptamine-1 receptors in the primate brain. Neuroscience. vol 18. issue 3. 1986-10-15. PMID:3748377. |
areas showing the highest density of 5-hydroxytryptamine-1 receptors (greater than 200 fmol [3h]5-hydroxytryptamine bound per mg tissue), included the cerebral cortex (laminae i-ii), claustrum, posterior cell group of the basal nucleus of meynert, the infracommissural part of the globus pallidus, cortical amygdaloid nucleus, hippocampal formation (ca1-subiculum region, the anterior ca2, ca3 and ca4 regions and the molecular layer of the dentate gyrus), thalamic nuclei (parafascicular, parataenial, paraventricular and superior central lateral nuclei), substantia nigra pars reticulata, dorsal raphe nucleus and choroid plexus. |
1986-10-15 |
2023-08-11 |
Not clear |
| O Hornykiewicz, S J Kish, L E Becker, I Farley, K Shanna. Brain neurotransmitters in dystonia musculorum deformans. The New England journal of medicine. vol 315. issue 6. 1986-09-17. PMID:2426591. |
the serotonin level was subnormal in the dorsal raphe nucleus, as was the dopamine level in the nucleus accumbens and, in one of the two cases, in the striatum. |
1986-09-17 |
2023-08-11 |
Not clear |
| O Hornykiewicz, S J Kish, L E Becker, I Farley, K Shanna. Brain neurotransmitters in dystonia musculorum deformans. The New England journal of medicine. vol 315. issue 6. 1986-09-17. PMID:2426591. |
elevated concentrations of norepinephrine were found in the septum, thalamus, colliculi, red nucleus, and dorsal raphe nucleus; of serotonin, in the globus pallidus, subthalamic nucleus, and locus ceruleus; and of 5-hydroxyindoleacetic acid, in the globus pallidus, subthalamic nucleus, and nuclei raphe centralis inferior and obscurus. |
1986-09-17 |
2023-08-11 |
Not clear |
| S Green, H Hodge. Differential effects of dorsal raphe lesions and intraraphe GABA and benzodiazepines on conflict behavior in rats. Behavioral and neural biology. vol 46. issue 1. 1986-08-13. PMID:3015119. |
lesions of the dorsal raphe produced by injections of 5,6-dihydroxytryptamine significantly increased punished responding, and there were significant correlations between lesion size, extent of forebrain serotonin depletion, and increases in punished responding. |
1986-08-13 |
2023-08-11 |
rat |
| R Mâgoul, B Onteniente, A Oblin, A Cala. Inter- and intracellular relationship of substance P-containing neurons with serotonin and GABA in the dorsal raphe nucleus: combination of autoradiographic and immunocytochemical techniques. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 34. issue 6. 1986-06-23. PMID:2422252. |
inter- and intracellular relationship of substance p-containing neurons with serotonin and gaba in the dorsal raphe nucleus: combination of autoradiographic and immunocytochemical techniques. |
1986-06-23 |
2023-08-11 |
rat |
| R Mâgoul, B Onteniente, A Oblin, A Cala. Inter- and intracellular relationship of substance P-containing neurons with serotonin and GABA in the dorsal raphe nucleus: combination of autoradiographic and immunocytochemical techniques. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 34. issue 6. 1986-06-23. PMID:2422252. |
double-labeling experiments were performed at the electron microscopic level in the dorsal raphe nucleus of rat, in order to study the inter- and intracellular relationship of substance p with gamma-aminobutyric acid (gaba) and serotonin. |
1986-06-23 |
2023-08-11 |
rat |
| R Mâgoul, B Onteniente, A Oblin, A Cala. Inter- and intracellular relationship of substance P-containing neurons with serotonin and GABA in the dorsal raphe nucleus: combination of autoradiographic and immunocytochemical techniques. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 34. issue 6. 1986-06-23. PMID:2422252. |
the results demonstrated that, in addition to reciprocal synaptic interactions made by substance p with serotonin and gaba, the dorsal raphe nucleus is the site of intracellular relationships between the peptide and either the amine or the amino acid. |
1986-06-23 |
2023-08-11 |
rat |
| M C McNamara, J L Gingras-Leatherman, E E Lawso. Effect of hypoxia on brainstem concentration of biogenic amines in postnatal rabbits. Brain research. vol 390. issue 2. 1986-04-28. PMID:3955374. |
radioenzymatic assays were used to determine the concentration of dopamine, norepinephrine and serotonin in the following brainstem nuclei: substantia nigra, locus coeruleus, dorsal raphe and the nucleus reticularis pontis oralis. |
1986-04-28 |
2023-08-11 |
rabbit |