| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Bonvento, P Lacombe, E T MacKenzie, L Rouquier, B Scatton, J Seyla. Differential effects of electrical stimulation of the dorsal raphe nucleus and of cervical sympathectomy on serotonin and noradrenaline concentrations in major cerebral arteries and pial vessels in the rat. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 10. issue 1. 1990-03-01. PMID:1688863. |
the levels of noradrenaline (na), serotonin (5-ht), and 5-hydroxyindoleacetic acid were measured by hplc and compared between the large arteries of the circle of willis and the small pial vessels in the rat, following either electrical stimulation of the dorsal raphe nucleus or bilateral superior cervical ganglionectomy. |
1990-03-01 |
2023-08-11 |
rat |
| b' F Radja, G Daval, M B Emerit, M C Gallissot, M Hamon, D Verg\\xc3\\xa. Selective irreversible blockade of 5-hydroxytryptamine1A and 5-hydroxytryptamine1C receptor binding sites in the rat brain by 8-MeO-2\'-chloro-PAT: a quantitative autoradiographic study. Neuroscience. vol 31. issue 3. 1990-01-25. PMID:2531850.' |
a marked reduction (-50% to -75%) of [3h]8-oh-dpat and [125i]bh-8-meo-n-pat specific binding to 5-hydroxytryptamine1a sites in the hippocampus (ca1 area) and the dorsal raphe nucleus, and of [3h]5-hydroxytryptamine specific binding to 5-hydroxytryptamine1c sites in the choroid plexus was found in sections exposed to 1 microm 8-meo-2'-chloro-pat and then washed extensively. |
1990-01-25 |
2023-08-11 |
rat |
| R B McCall, M E Clement, L T Harri. Studies on the mechanism of the sympatholytic effect of 8-OH DPAT: lack of correlation between inhibition of serotonin neuronal firing and sympathetic activity. Brain research. vol 501. issue 1. 1989-12-20. PMID:2529951. |
medullary 5-ht neurons were identified using criteria modeled after the electrophysiological and pharmacological characteristics previously described for dorsal raphe 5-ht neurons. |
1989-12-20 |
2023-08-11 |
Not clear |
| J Williams, M Lace. Actions of cocaine on central monoamine neurons: intracellular recordings in vitro. NIDA research monograph. vol 90. 1989-12-05. PMID:3151928. |
in the locus coeruleus and dorsal raphe cocaine prolonged an inhibitory postsynaptic potential caused by the release of noradrenaline and 5-ht respectively. |
1989-12-05 |
2023-08-11 |
Not clear |
| J S Sprouse, C W Bradberry, R H Roth, G K Aghajania. MDMA (3,4-methylenedioxymethamphetamine) inhibits the firing of dorsal raphe neurons in brain slices via release of serotonin. European journal of pharmacology. vol 167. issue 3. 1989-11-27. PMID:2572435. |
mdma (3,4-methylenedioxymethamphetamine) inhibits the firing of dorsal raphe neurons in brain slices via release of serotonin. |
1989-11-27 |
2023-08-11 |
Not clear |
| J S Sprouse, C W Bradberry, R H Roth, G K Aghajania. MDMA (3,4-methylenedioxymethamphetamine) inhibits the firing of dorsal raphe neurons in brain slices via release of serotonin. European journal of pharmacology. vol 167. issue 3. 1989-11-27. PMID:2572435. |
the effects of mdma (3,4-methylenedioxymethamphetamine) on the activity of serotonin (5-ht)-containing dorsal raphe neurons were characterized using extracellular single-unit recording and microdialysis techniques in the in vitro midbrain slice preparation. |
1989-11-27 |
2023-08-11 |
Not clear |
| J S Sprouse, C W Bradberry, R H Roth, G K Aghajania. MDMA (3,4-methylenedioxymethamphetamine) inhibits the firing of dorsal raphe neurons in brain slices via release of serotonin. European journal of pharmacology. vol 167. issue 3. 1989-11-27. PMID:2572435. |
pretreatment with the selective 5-ht uptake inhibitor fluoxetine, at a concentration which had no effect on baseline firing (20 microm), blocked the inhibitory effect of (+)-mdma and pca on dorsal raphe neurons. |
1989-11-27 |
2023-08-11 |
Not clear |
| J S Sprouse, C W Bradberry, R H Roth, G K Aghajania. MDMA (3,4-methylenedioxymethamphetamine) inhibits the firing of dorsal raphe neurons in brain slices via release of serotonin. European journal of pharmacology. vol 167. issue 3. 1989-11-27. PMID:2572435. |
in a parallel series of experiments, microdialysis probes resting on the brain slice surface provided a means to estimate 5-ht release from the dorsal raphe nucleus. |
1989-11-27 |
2023-08-11 |
Not clear |
| J S Sprouse, C W Bradberry, R H Roth, G K Aghajania. MDMA (3,4-methylenedioxymethamphetamine) inhibits the firing of dorsal raphe neurons in brain slices via release of serotonin. European journal of pharmacology. vol 167. issue 3. 1989-11-27. PMID:2572435. |
(+)-mdma (100 microm) caused the release of measureable quantities of 5-ht with a time course which corresponded to the change in dorsal raphe cell firing rate. |
1989-11-27 |
2023-08-11 |
Not clear |
| J S Sprouse, C W Bradberry, R H Roth, G K Aghajania. MDMA (3,4-methylenedioxymethamphetamine) inhibits the firing of dorsal raphe neurons in brain slices via release of serotonin. European journal of pharmacology. vol 167. issue 3. 1989-11-27. PMID:2572435. |
taken together, these data suggest that mdma acts indirectly to inhibit dorsal raphe neurons through release of endogenous 5-ht. |
1989-11-27 |
2023-08-11 |
Not clear |
| B Prieto-Gómez, N Dafny, C Reyes-Vázque. Dorsal raphe stimulation, 5-HT and morphine microiontophoresis effects on noxious and nonnoxious identified neurons in the medial thalamus of the rat. Brain research bulletin. vol 22. issue 6. 1989-11-08. PMID:2790499. |
dorsal raphe stimulation, 5-ht and morphine microiontophoresis effects on noxious and nonnoxious identified neurons in the medial thalamus of the rat. |
1989-11-08 |
2023-08-11 |
rat |
| B Prieto-Gómez, N Dafny, C Reyes-Vázque. Dorsal raphe stimulation, 5-HT and morphine microiontophoresis effects on noxious and nonnoxious identified neurons in the medial thalamus of the rat. Brain research bulletin. vol 22. issue 6. 1989-11-08. PMID:2790499. |
in single cell experiments, the characterization of the responses of medial thalamic neurons to noxious and nonnoxious stimulation was made to examine the effects of two substances involved in pain, morphine and 5-ht, and the action of one pain suppressor mechanism, dorsal raphe stimulation. |
1989-11-08 |
2023-08-11 |
rat |
| B Prieto-Gómez, N Dafny, C Reyes-Vázque. Dorsal raphe stimulation, 5-HT and morphine microiontophoresis effects on noxious and nonnoxious identified neurons in the medial thalamus of the rat. Brain research bulletin. vol 22. issue 6. 1989-11-08. PMID:2790499. |
morphine, 5-ht microiontophoresis and dorsal raphe stimulation were performed in all the recorded units. |
1989-11-08 |
2023-08-11 |
rat |
| B Prieto-Gómez, N Dafny, C Reyes-Vázque. Dorsal raphe stimulation, 5-HT and morphine microiontophoresis effects on noxious and nonnoxious identified neurons in the medial thalamus of the rat. Brain research bulletin. vol 22. issue 6. 1989-11-08. PMID:2790499. |
dorsal raphe stimulation and 5-ht ejection prevented the excitation elicited by noxious input. |
1989-11-08 |
2023-08-11 |
rat |
| B Prieto-Gómez, N Dafny, C Reyes-Vázque. Dorsal raphe stimulation, 5-HT and morphine microiontophoresis effects on noxious and nonnoxious identified neurons in the medial thalamus of the rat. Brain research bulletin. vol 22. issue 6. 1989-11-08. PMID:2790499. |
morphine ejection prevented both the noxious and nonnoxious input in medial thalamus, in a different population as compared to dorsal raphe stimulation or 5-ht ejection. |
1989-11-08 |
2023-08-11 |
rat |
| J P Rivot, D Pointis, J M Besso. A comparison of the effects of morphine on 5-HT metabolism in the periaqueductal gray, ventromedial medulla and medullary dorsal horn: in vivo electrochemical studies in freely moving rats. Brain research. vol 495. issue 1. 1989-10-19. PMID:2776031. |
the effect of systemic morphine on serotonin (5-ht) metabolism within the dorsal raphe nucleus (drn) has been investigated by in vivo 5-hydroxyindole electrochemical (peak '3') detection in freely moving rats. |
1989-10-19 |
2023-08-11 |
rat |
| Z Z Pan, W F Colmers, J T William. 5-HT-mediated synaptic potentials in the dorsal raphe nucleus: interactions with excitatory amino acid and GABA neurotransmission. Journal of neurophysiology. vol 62. issue 2. 1989-10-12. PMID:2788717. |
the results indicate that the ipsp recorded in dorsal raphe neurons was caused by 5-ht released at least in part from indirect (synaptically induced) excitation of 5-ht-containing cells within the slice. |
1989-10-12 |
2023-08-11 |
rat |
| B E Jones, A C Cuell. Afferents to the basal forebrain cholinergic cell area from pontomesencephalic--catecholamine, serotonin, and acetylcholine--neurons. Neuroscience. vol 31. issue 1. 1989-10-06. PMID:2475819. |
of the total population of retrogradely labelled neurons, a significant (approximately 25%) proportion were tyrosine hydroxylase-immunoreactive and found in the ventral tegmental area (a10), the substantia nigra (a9), the retrorubral field (a8), the raphe nuclei (dorsalis, linearis and interfascicularis) and the locus coeruleus nucleus (a6), another important contingent (approximately 10%) was represented by serotonin neurons of the dorsal raphe nucleus (b7), the central superior nucleus (b8) and ventral tegmentum (b9). |
1989-10-06 |
2023-08-11 |
Not clear |
| K Iwayama, K Mori, M Fukushima, K Yamashir. Effect of midbrain raphe nucleus stimulation on somatosensory evoked potential in cat. Neurological research. vol 11. issue 2. 1989-09-21. PMID:2569680. |
experiments were carried out to clarify the effect of serotonin [5-hydroxytryptamine (5-ht)] upon the somatosensory evoked potential (sep) elicited by superficial radial nerve stimulation in cat, and the following results were obtained: (i) in untreated (control) animals, a significant reduction occurred in amplitude of the sep in response to conditioning stimulation of the dorsal raphe nucleus in the midbrain, within 100 ms of the interval between conditioning and test stimuli; (ii) in 5-ht depleted animals prepared by intraperitoneal injection of p-chlorophenylalanine (pcpa), the amplitude of sep significantly increased in comparison with that of nontreated animals. |
1989-09-21 |
2023-08-11 |
cat |
| P H Hutson, G S Sarna, M T O'Connell, G Curzo. Hippocampal 5-HT synthesis and release in vivo is decreased by infusion of 8-OHDPAT into the nucleus raphe dorsalis. Neuroscience letters. vol 100. issue 1-3. 1989-09-15. PMID:2474776. |
infusion of the serotonin-1a (5-ht1a) agonist, 8-hydroxy-2-di(n-propylamino)tetralin (8-ohdpat) (0.5, 1.0 and 2.0 micrograms) into the dorsal raphe, decreased extracellular 5-ht as measured by dialysis in the ventral hippocampus and also decreased 5-ht synthesis in both the hippocampus and the rest of the brain as measured by 5-hydroxytryptophan (5-htp) accumulation following decarboxylase inhibition by nsd 1015. |
1989-09-15 |
2023-08-11 |
Not clear |