| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J S Sprouse, C W Bradberry, R H Roth, G K Aghajania. 3,4-Methylenedioxymethamphetamine-induced release of serotonin and inhibition of dorsal raphe cell firing: potentiation by L-tryptophan. European journal of pharmacology. vol 178. issue 3. 1990-06-27. PMID:1971220. |
pretreatment with l-tryptophan increased mdma-induced 5-ht release in a manner consistent with the suppression of dorsal raphe cell firing: compared to untreated preparations, peak 5-ht release, total release and the duration of release were all increased. |
1990-06-27 |
2023-08-11 |
Not clear |
| J S Sprouse, C W Bradberry, R H Roth, G K Aghajania. 3,4-Methylenedioxymethamphetamine-induced release of serotonin and inhibition of dorsal raphe cell firing: potentiation by L-tryptophan. European journal of pharmacology. vol 178. issue 3. 1990-06-27. PMID:1971220. |
taken together, these data suggest that the enhancement by l-tryptophan of mdma-induced 5-ht release and inhibition of dorsal raphe neuronal firing is due to an increase in the amount of 5-ht available for release. |
1990-06-27 |
2023-08-11 |
Not clear |
| M D Kelland, A S Freeman, L A Chiod. Serotonergic afferent regulation of the basic physiology and pharmacological responsiveness of nigrostriatal dopamine neurons. The Journal of pharmacology and experimental therapeutics. vol 253. issue 2. 1990-06-21. PMID:1971022. |
the electrophysiological responsiveness of nigrostriatal dopamine (da) neurons to dorsal raphe stimulation and to systemic administration of serotonin (5-ht) selective compounds was examined in chloral hydrate-anesthetized rats. |
1990-06-21 |
2023-08-11 |
rat |
| A T Dolzhenko, I V Komissarov, N A Khari. [The comparative effect of serotonin agonists on the presynaptic and somatodendritic autoreceptors of serotoninergic neurons]. Biulleten' eksperimental'noi biologii i meditsiny. vol 108. issue 12. 1990-06-04. PMID:2634439. |
experimenting on the slices of cortex and dorsal raphe nucleus of midbrain of rats which were incubated with 3h-hydroxytrypta-mine (3h-ht) studies showed the influence of series of serotonin agonists on the spontaneous and electrically stimulated release of 3h-ht from the slices. |
1990-06-04 |
2023-08-11 |
rat |
| A T Dolzhenko, I V Komissarov, N A Khari. [The comparative effect of serotonin agonists on the presynaptic and somatodendritic autoreceptors of serotoninergic neurons]. Biulleten' eksperimental'noi biologii i meditsiny. vol 108. issue 12. 1990-06-04. PMID:2634439. |
it was established that the serotonin in concentration of 10(-5) mol/l similarly inhibits the release of 3h-ht from the electrically stimulated slices of the brain cortex (78.6%) and on slices of the dorsal raphe nucleus of the midbrain (81.6%) had no effect on the spontaneous release of serotonin. |
1990-06-04 |
2023-08-11 |
rat |
| A T Dolzhenko, I V Komissarov, N A Khari. [The comparative effect of serotonin agonists on the presynaptic and somatodendritic autoreceptors of serotoninergic neurons]. Biulleten' eksperimental'noi biologii i meditsiny. vol 108. issue 12. 1990-06-04. PMID:2634439. |
on the ability to influence the release of 3h-ht from the electrically stimulated slices of the dorsal raphe nucleus of the midbrain of the rats serotonin agonists were in the following order: tempp (12.3%), kampirone (40%), 1.2-pp (42.9%), ipsapirone (52%), 8-oh-dpat (54.1%), kampirone (57.2%) and buspirone (65.3%). |
1990-06-04 |
2023-08-11 |
rat |
| I K Wright, J C Garratt, C A Marsde. Effects of a selective 5-HT2 agonist, DOI, on 5-HT neuronal firing in the dorsal raphe nucleus and 5-HT release and metabolism in the frontal cortex. British journal of pharmacology. vol 99. issue 2. 1990-05-30. PMID:1691671. |
effects of a selective 5-ht2 agonist, doi, on 5-ht neuronal firing in the dorsal raphe nucleus and 5-ht release and metabolism in the frontal cortex. |
1990-05-30 |
2023-08-11 |
Not clear |
| A Hirose, M Sasa, A Akaike, S Takaor. Inhibition of hippocampal CA1 neurons by 5-hydroxytryptamine, derived from the dorsal raphe nucleus and the 5-hydroxytryptamine1A agonist SM-3997. Neuropharmacology. vol 29. issue 2. 1990-05-30. PMID:1970426. |
inhibition of hippocampal ca1 neurons by 5-hydroxytryptamine, derived from the dorsal raphe nucleus and the 5-hydroxytryptamine1a agonist sm-3997. |
1990-05-30 |
2023-08-11 |
rat |
| A Hirose, M Sasa, A Akaike, S Takaor. Inhibition of hippocampal CA1 neurons by 5-hydroxytryptamine, derived from the dorsal raphe nucleus and the 5-hydroxytryptamine1A agonist SM-3997. Neuropharmacology. vol 29. issue 2. 1990-05-30. PMID:1970426. |
electrophysiological studies, using chloral hydrate-anesthetized rats, were undertaken to determine whether hippocampal pyramidal neurons, receiving input from the medial septal nucleus, were affected by 5-hydroxytryptamine (5-ht) derived from the dorsal raphe nucleus. |
1990-05-30 |
2023-08-11 |
rat |
| A Hirose, M Sasa, A Akaike, S Takaor. Inhibition of hippocampal CA1 neurons by 5-hydroxytryptamine, derived from the dorsal raphe nucleus and the 5-hydroxytryptamine1A agonist SM-3997. Neuropharmacology. vol 29. issue 2. 1990-05-30. PMID:1970426. |
in the short-latency neurons, the stimulation-induced spikes of the medial septal nucleus were inhibited by conditioning stimuli applied to the dorsal raphe nucleus and iontophoretic application of 5-ht and the 5-ht1a agonists, sm-3997 (3 a alpha,4 beta,7 beta,7a alpha-hexahydro-2-(4-(4-(2-pyrimidinyl)-1- piperazinyl)-butyl)-4,7-methano-1h-isoindole-1,3(2h)-dione dihydrogen citrate) and 8-oh-dpat (8-hydroxy-2-(di-n-propylamino)tetralin). |
1990-05-30 |
2023-08-11 |
rat |
| A Hirose, M Sasa, A Akaike, S Takaor. Inhibition of hippocampal CA1 neurons by 5-hydroxytryptamine, derived from the dorsal raphe nucleus and the 5-hydroxytryptamine1A agonist SM-3997. Neuropharmacology. vol 29. issue 2. 1990-05-30. PMID:1970426. |
however, in the long-latency neurons, the spikes elicited by stimulation of the medial septal nucleus were not affected by the conditioning stimulation of the dorsal raphe nucleus, or iontophoretically applied 5-ht. |
1990-05-30 |
2023-08-11 |
rat |
| A Hirose, M Sasa, A Akaike, S Takaor. Inhibition of hippocampal CA1 neurons by 5-hydroxytryptamine, derived from the dorsal raphe nucleus and the 5-hydroxytryptamine1A agonist SM-3997. Neuropharmacology. vol 29. issue 2. 1990-05-30. PMID:1970426. |
these results indicate that 5-ht, originating in the dorsal raphe nucleus inhibited hippocampal pyramidal neurons receiving cholinergic input from the medial septal nucleus, but not those receiving non-cholinergic input from the medial septal nucleus. |
1990-05-30 |
2023-08-11 |
rat |
| A N Talalaenk. [The role of neurochemical mechanisms of the dorsal raphe nucleus in various models of anxiety states in rats]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 39. issue 6. 1990-04-16. PMID:2576490. |
dopamine and serotonin microinjection in the dorsal raphe nucleus of rats does not influence the alarm state in the test of "threatening situation" avoidance, but increases or weakens the state of alarm in the rest of "illuminated site" avoidance. |
1990-04-16 |
2023-08-11 |
rat |
| P Blier, A Serrano, B Scatto. Differential responsiveness of the rat dorsal and median raphe 5-HT systems to 5-HT1 receptor agonists and p-chloroamphetamine. Synapse (New York, N.Y.). vol 5. issue 2. 1990-04-09. PMID:2137943. |
first, the microiontophoretic application of 8-oh-dpat directly onto 5-ht neurons was three times more potent in suppressing the firing rate of dorsal raphe 5-ht neurons than that of their median raphe congeners. |
1990-04-09 |
2023-08-11 |
rat |
| K A Cunningham, J M Lakosk. The interaction of cocaine with serotonin dorsal raphe neurons. Single-unit extracellular recording studies. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 3. issue 1. 1990-04-05. PMID:2137698. |
the interaction of cocaine with serotonin dorsal raphe neurons. |
1990-04-05 |
2023-08-11 |
rat |
| K A Cunningham, J M Lakosk. The interaction of cocaine with serotonin dorsal raphe neurons. Single-unit extracellular recording studies. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 3. issue 1. 1990-04-05. PMID:2137698. |
cocaine potently inhibits the spontaneous activity of dorsal raphe serotonin (5-hydroxytryptamine [5-ht] neurons which possess impulse-modulating receptors of the 5-ht1a subtype. |
1990-04-05 |
2023-08-11 |
rat |
| K A Cunningham, J M Lakosk. The interaction of cocaine with serotonin dorsal raphe neurons. Single-unit extracellular recording studies. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 3. issue 1. 1990-04-05. PMID:2137698. |
in an investigation of the neuropharmacologic mechanisms underlying this electrophysiologic effect, we have compared cocaine with structurally and functionally similar compounds, attempted to reverse cocaine-induced suppression of 5-ht dorsal raphe nucleus (drn) neuronal activity, and assessed the effects of 5-ht depletion on the response to cocaine. |
1990-04-05 |
2023-08-11 |
rat |
| C Reyes-Vazquez, J T Qiao, N Dafn. Nociceptive responses in nucleus parafascicularis thalami are modulated by dorsal raphe stimulation and microiontophoretic application of morphine and serotonin. Brain research bulletin. vol 23. issue 6. 1990-03-08. PMID:2611684. |
nociceptive responses in nucleus parafascicularis thalami are modulated by dorsal raphe stimulation and microiontophoretic application of morphine and serotonin. |
1990-03-08 |
2023-08-11 |
Not clear |
| C Reyes-Vazquez, J T Qiao, N Dafn. Nociceptive responses in nucleus parafascicularis thalami are modulated by dorsal raphe stimulation and microiontophoretic application of morphine and serotonin. Brain research bulletin. vol 23. issue 6. 1990-03-08. PMID:2611684. |
the observations demonstrate that: 1) dorsal raphe stimulation (drs) modulates the spontaneous activity and the noxious-evoked responses of parafasciculus (pf) neurons, and the modulating effects of drs are altered by either naloxone or methysergide; 2) morphine ejection into the pf alters the spontaneous activity and the noxious-evoked responses of pf neurons, and naloxone prevents morphine effects; and 3) serotonin ejection into the pf alters the spontaneous activity and the noxious-evoked responses of pf neurons and methysergide prevents the serotonin effects. |
1990-03-08 |
2023-08-11 |
Not clear |
| G Bonvento, P Lacombe, E T MacKenzie, L Rouquier, B Scatton, J Seyla. Differential effects of electrical stimulation of the dorsal raphe nucleus and of cervical sympathectomy on serotonin and noradrenaline concentrations in major cerebral arteries and pial vessels in the rat. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 10. issue 1. 1990-03-01. PMID:1688863. |
differential effects of electrical stimulation of the dorsal raphe nucleus and of cervical sympathectomy on serotonin and noradrenaline concentrations in major cerebral arteries and pial vessels in the rat. |
1990-03-01 |
2023-08-11 |
rat |