| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| b' Giulia D\'Intino, Michela Paradisi, Mercedes Fernandez, Alessandro Giuliani, Luigi Aloe, Luciana Giardino, Laura Calz\\xc3\\xa. Cognitive deficit associated with cholinergic and nerve growth factor down-regulation in experimental allergic encephalomyelitis in rats. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 8. 2005-03-24. PMID:15710875.' |
in this paper we demonstrate that a selective deficit in learning and memory performance, as investigated by the morris water maze test, is a consistent feature in rat encephalomyelitis, which correlates with a decline in choline acetyltransferase activity and nerve growth factor mrna level in cerebral cortex, hippocampus, and basal forebrain. |
2005-03-24 |
2023-08-12 |
rat |
| Jin Hyeong Jhoo, Hyoung-Chun Kim, Toshitaka Nabeshima, Kiyofumi Yamada, Eun-Joo Shin, Wang-Kee Jhoo, Wookyung Kim, Kee-Seok Kang, Sangmee Ahn Jo, Jong Inn Wo. Beta-amyloid (1-42)-induced learning and memory deficits in mice: involvement of oxidative burdens in the hippocampus and cerebral cortex. Behavioural brain research. vol 155. issue 2. 2005-01-13. PMID:15364477. |
beta-amyloid (1-42)-induced learning and memory deficits in mice: involvement of oxidative burdens in the hippocampus and cerebral cortex. |
2005-01-13 |
2023-08-12 |
mouse |
| Thomas van Groen, Inga Kadish, J Michael Wys. Retrosplenial cortex lesions of area Rgb (but not of area Rga) impair spatial learning and memory in the rat. Behavioural brain research. vol 154. issue 2. 2004-11-01. PMID:15313037. |
retrosplenial cortex lesions of area rgb (but not of area rga) impair spatial learning and memory in the rat. |
2004-11-01 |
2023-08-12 |
rat |
| Thomas van Groen, Inga Kadish, J Michael Wys. Retrosplenial cortex lesions of area Rgb (but not of area Rga) impair spatial learning and memory in the rat. Behavioural brain research. vol 154. issue 2. 2004-11-01. PMID:15313037. |
this study tests the hypothesis that the two areas of the retrosplenial granular cortex play distinct roles in spatial learning and memory. |
2004-11-01 |
2023-08-12 |
rat |
| Silvia Middei, Raffaella Geracitano, Antonio Caprioli, Nicola Mercuri, Martine Ammassari-Teul. Preserved fronto-striatal plasticity and enhanced procedural learning in a transgenic mouse model of Alzheimer's disease overexpressing mutant hAPPswe. Learning & memory (Cold Spring Harbor, N.Y.). vol 11. issue 4. 2004-09-23. PMID:15286183. |
although tg2576 mice with the swedish mutation (happswe) exhibit age-related abeta-plaque formation in brain regions like the hippocampus, the amygdala, and the cortex, these mice show a rather specific deficit in hippocampal-dependent learning and memory tasks. |
2004-09-23 |
2023-08-12 |
mouse |
| Cláudia Pereira, Elisabete Ferreiro, Sandra Morais Cardoso, Catarina Resende de Oliveir. Cell degeneration induced by amyloid-beta peptides: implications for Alzheimer's disease. Journal of molecular neuroscience : MN. vol 23. issue 1-2. 2004-09-01. PMID:15126695. |
extracellular accumulation of amyloid-beta (abeta) peptide and death of neurons in brain regions involved in learning and memory, particularly the cortex and the hippocampus, are central features of alzheimer's disease (ad). |
2004-09-01 |
2023-08-12 |
Not clear |
| F Maekawa, S Tsukahara, K Tanaka, H Ohki-Hamazak. Distributions of two chicken bombesin receptors, bombesin receptor subtype-3.5 (chBRS-3.5) and gastrin-releasing peptide receptor (chGRP-R) mRNAS in the chicken telencephalon. Neuroscience. vol 125. issue 3. 2004-08-02. PMID:15099671. |
abundant expressions in the hyperpallium, nidopallium, considered to be similar to the mammalian cortex, as well as in the hippocampus, indicate participation of these molecules in the processing of sensory information, motor function, learning and memory. |
2004-08-02 |
2023-08-12 |
chicken |
| Masahiko Morita, Atsuo Suemits. Computational modeling of pair-association memory in inferior temporal cortex. Brain research. Cognitive brain research. vol 13. issue 2. 2004-07-22. PMID:11958959. |
it is reasonable to presume that n1 and n2 correspond to area te and the rhinal cortex, respectively; based on this theory, we explain some physiological findings on learning and memory, and also make several predictions. |
2004-07-22 |
2023-08-12 |
monkey |
| Masanori Matsuzaki, Naoki Honkura, Graham C R Ellis-Davies, Haruo Kasa. Structural basis of long-term potentiation in single dendritic spines. Nature. vol 429. issue 6993. 2004-07-16. PMID:15190253. |
dendritic spines of pyramidal neurons in the cerebral cortex undergo activity-dependent structural remodelling that has been proposed to be a cellular basis of learning and memory. |
2004-07-16 |
2023-08-12 |
Not clear |
| Carlos A Saura, Se-Young Choi, Vassilios Beglopoulos, Seema Malkani, Dawei Zhang, B S Shankaranarayana Rao, Sumantra Chattarji, Raymond J Kelleher, Eric R Kandel, Karen Duff, Alfredo Kirkwood, Jie She. Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration. Neuron. vol 42. issue 1. 2004-05-27. PMID:15066262. |
these results define essential roles and molecular targets of presenilins in synaptic plasticity, learning and memory, and neuronal survival in the adult cerebral cortex. |
2004-05-27 |
2023-08-12 |
mouse |
| Keith K Murai, Louis N Nguyen, Mitchell Koolpe, Rebecca McLennan, Catherine E Krull, Elena B Pasqual. Targeting the EphA4 receptor in the nervous system with biologically active peptides. Molecular and cellular neurosciences. vol 24. issue 4. 2004-02-27. PMID:14697664. |
in the adult, epha4 is enriched in the hippocampus and cortex, two brain structures critical for learning and memory. |
2004-02-27 |
2023-08-12 |
chicken |
| C C Wrenn, L K Marriott, J W Kinney, A Holmes, G L Wenk, J N Crawle. Galanin peptide levels in hippocampus and cortex of galanin-overexpressing transgenic mice evaluated for cognitive performance. Neuropeptides. vol 36. issue 6. 2004-02-24. PMID:12507436. |
the present study employed radioimmunoassay to quantitate the level of galanin peptide overexpression in two brain regions relevant to learning and memory, the hippocampus and cerebral cortex. |
2004-02-24 |
2023-08-12 |
mouse |
| Abdallah Hadj Tahar, Pierre J Blanchet, Julien Doyo. Motor-learning impairment by amantadine in healthy volunteers. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 1. 2004-02-17. PMID:14532914. |
nmda receptor antagonists impair learning and memory in animal models, presumably by inhibiting long-term potentiation in the motor cortex. |
2004-02-17 |
2023-08-12 |
human |
| Anna Josephson, Alexandra Trifunovski, Camilla Schéele, Johan Widenfalk, Claes Wahlestedt, Stefan Brené, Lars Olson, Christian Spenge. Activity-induced and developmental downregulation of the Nogo receptor. Cell and tissue research. vol 311. issue 3. 2004-02-11. PMID:12658441. |
strong, rapid and transient downregulation of ngr mrna in response to kainic acid and after wheel running in cortex and hippocampus suggests a role for ngr and nogo-a in plasticity, learning and memory. |
2004-02-11 |
2023-08-12 |
rat |
| Bombi Lee, YoungKook Choi, Hocheol Kim, Sun Yeou Kim, Dae-Hyun Hahm, Hye-Jung Lee, Insop Shi. Protective effects of methanol extract of Acori graminei rhizoma and Uncariae Ramulus et Uncus on ischemia-induced neuronal death and cognitive impairments in the rat. Life sciences. vol 74. issue 4. 2004-01-29. PMID:14609722. |
in order to investigate whether agr and ure influenced cerebral ischemia-induced neuronal and cognitive impairments, we examined the effect of agr and ure on ischemia-induced cell death in the striatum, cortex and hippocampus, and on the impaired learning and memory in the morris water maze and radial eight-arm maze in rats. |
2004-01-29 |
2023-08-12 |
rat |
| Z Liao, Z Qi, M Sun, D Yang, J Yu. [The influences of human apolipoprotein E mutants on the learning and memory of cerebral cortex in transgenic mice]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. vol 22. issue 4. 2004-01-06. PMID:12903448. |
[the influences of human apolipoprotein e mutants on the learning and memory of cerebral cortex in transgenic mice]. |
2004-01-06 |
2023-08-12 |
mouse |
| Tatjana A Ishunina, Joop J van Heerikhuize, Rivka Ravid, Dick F Swaa. Estrogen receptors and metabolic activity in the human tuberomamillary nucleus: changes in relation to sex, aging and Alzheimer's disease. Brain research. vol 988. issue 1-2. 2003-12-10. PMID:14519529. |
the human tuberomamillary nucleus (tmn), that is the sole source of histamine in the brain, is involved in arousal, learning and memory and is impaired in alzheimer's disease (ad) as shown by the presence of cytoskeletal alterations, a reduction in the number of large neurons, a diminished neuronal metabolic activity and decreased histamine levels in the hypothalamus and cortex. |
2003-12-10 |
2023-08-12 |
human |
| R Bartesaghi, M Raffi, S Sever. Effects of early isolation on layer II neurons in the entorhinal cortex of the guinea pig. Neuroscience. vol 120. issue 3. 2003-12-04. PMID:12895512. |
the presence of widespread effects of isolation in the entorhinal cortex and numerous hippocampal structures suggests that the outcome of early isolation might be a change in learning and memory functions requiring the hippocampal region. |
2003-12-04 |
2023-08-12 |
Not clear |
| D Yaniv, R M Vouimba, D M Diamond, G Richter-Levi. Simultaneous induction of long-term potentiation in the hippocampus and the amygdala by entorhinal cortex activation: mechanistic and temporal profiles. Neuroscience. vol 120. issue 4. 2003-11-10. PMID:12927217. |
the medial temporal lobe, including the entorhinal cortex, the amygdala and the hippocampus, has an important role in learning and memory, and its circuits exhibit synaptic plasticity (long-term potentiation [ltp]). |
2003-11-10 |
2023-08-12 |
rat |
| Koji Onodera, Nao-Omi Omoi, Koji Fukui, Takahiro Hayasaka, Tadashi Shinkai, Shozo Suzuki, Kouichi Abe, Shiro Uran. Oxidative damage of rat cerebral cortex and hippocampus, and changes in antioxidative defense systems caused by hyperoxia. Free radical research. vol 37. issue 4. 2003-10-10. PMID:12747730. |
in order to elucidate the oxidative damage in rat brain caused by oxidative stress, regional changes in the levels of lipid peroxidation products and antioxidative defense systems in cerebral cortex and hippocampus, and in their synapses, which modulate learning and memory functions in the brain, were studied. |
2003-10-10 |
2023-08-12 |
rat |