| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sarah Melzer, Magdalena Michael, Antonio Caputi, Marina Eliava, Elke C Fuchs, Miles A Whittington, Hannah Monye. Long-range-projecting GABAergic neurons modulate inhibition in hippocampus and entorhinal cortex. Science (New York, N.Y.). vol 335. issue 6075. 2012-04-09. PMID:22442486. |
the hippocampus and entorhinal cortex play a pivotal role in spatial learning and memory. |
2012-04-09 |
2023-08-12 |
Not clear |
| Rui Liu, Tiantai Zhang, Haiguang Yang, Xi Lan, Jian Ying, Guanhua D. The flavonoid apigenin protects brain neurovascular coupling against amyloid-β₂₅₋₃₅-induced toxicity in mice. Journal of Alzheimer's disease : JAD. vol 24. issue 1. 2012-03-06. PMID:21297270. |
the learning and memory impairments, changes in morphology of major components of neurovascular unit, ultrastructural changes and oxidative stress of cerebral cortex, cerebrovascular dysfunction, and neuronal changes were detected after oral administration of apigenin continuously for 8 days. |
2012-03-06 |
2023-08-12 |
mouse |
| Valentina Echeverria, Ross Zeitlin, Sarah Burgess, Sagar Patel, Arghya Barman, Garima Thakur, Magorzota Mamcarz, Li Wang, David B Sattelle, Daniel A Kirschner, Takashi Mori, Roger M Leblanc, Rajeev Prabhakar, Gary W Arendas. Cotinine reduces amyloid-β aggregation and improves memory in Alzheimer's disease mice. Journal of Alzheimer's disease : JAD. vol 24. issue 4. 2012-02-09. PMID:21321389. |
cotinine stimulated akt signaling, including the inhibition of glycogen synthase kinase 3β (gsk3β), which promotes neuronal survival and the synaptic plasticity processes underlying learning and memory in the hippocampus and cortex of wild type and tg6799 ad mice. |
2012-02-09 |
2023-08-12 |
mouse |
| Liang Cheng, Shao-Hui Wang, Qi-Cai Chen, Xiao-Mei Lia. Moderate noise induced cognition impairment of mice and its underlying mechanisms. Physiology & behavior. vol 104. issue 5. 2012-02-06. PMID:21726571. |
to explore potential mechanisms, we determined levels of oxidative stress in the inferior colliculus (ic), auditory cortex (ac), and hippocampus (the structures comprising the critical encephalic region associated with the acoustic lemniscal ascending pathway), the phosphorylation of microtubule-associated protein tau in the hippocampus (important role in learning and memory), and the basic auditory response properties of neurons in the ic. |
2012-02-06 |
2023-08-12 |
mouse |
| Desiree N Lavin, Jennifer J Joesting, Gabriel S Chiu, Morgan L Moon, Jia Meng, Ryan N Dilger, Gregory G Freun. Fasting induces an anti-inflammatory effect on the neuroimmune system which a high-fat diet prevents. Obesity (Silver Spring, Md.). vol 19. issue 8. 2012-01-17. PMID:21527899. |
mouse learning and memory (spontaneous alternation, novel object) and depressive-like behaviors (saccharin preference, burrowing, forced swim) were studied in the fed and fasted state as were gene transcripts for f4/80, cd11b, interleukin-1α (il-1α), il-1β, il-1r1, il-1r2, il-1ra, il-6 and tumor necrosis factor-α in cortex, hippocampus and hypothalamus. |
2012-01-17 |
2023-08-12 |
mouse |
| Alexis M Stranahan, Sebastian Salas-Vega, Nicole T Jiam, Michela Gallaghe. Interference with reelin signaling in the lateral entorhinal cortex impairs spatial memory. Neurobiology of learning and memory. vol 96. issue 2. 2011-12-27. PMID:21492744. |
to determine whether interrupting entorhinal reelin signaling might have consequences for learning and memory, we administered recombinant receptor-associated protein (rap) into the lateral entorhinal cortex (lec) of young long-evans rats. |
2011-12-27 |
2023-08-12 |
rat |
| Qing-Song Jiang, Zi-Liang Liang, Min-Jie Wu, Lin Feng, Li-Li Liu, Jian-Jun Zhan. Reduced brain-derived neurotrophic factor expression in cortex and hippocampus involved in the learning and memory deficit in molarless SAMP8 mice. Chinese medical journal. vol 124. issue 10. 2011-12-14. PMID:21740813. |
reduced brain-derived neurotrophic factor expression in cortex and hippocampus involved in the learning and memory deficit in molarless samp8 mice. |
2011-12-14 |
2023-08-12 |
mouse |
| Venu Narayanan, Rebecca S Heiming, Friederike Jansen, Jörg Lesting, Norbert Sachser, Hans-Christian Pape, Thomas Seidenbeche. Social defeat: impact on fear extinction and amygdala-prefrontal cortical theta synchrony in 5-HTT deficient mice. PloS one. vol 6. issue 7. 2011-12-06. PMID:21818344. |
in conclusion, extinction learning and memory of conditioned fear can be modulated by both the 5-htt gene activity and social experiences in adulthood, accompanied by corresponding alterations of the theta activity in the amygdala-prefrontal cortex network. |
2011-12-06 |
2023-08-12 |
mouse |
| Siobhan Robinson, Christopher S Keene, Hannah F Iaccarino, Daisy Duan, David J Bucc. Involvement of retrosplenial cortex in forming associations between multiple sensory stimuli. Behavioral neuroscience. vol 125. issue 4. 2011-11-29. PMID:21688884. |
the retrosplenial cortex (rsp) is highly interconnected with medial temporal lobe structures, yet relatively little is known about its specific contributions to learning and memory. |
2011-11-29 |
2023-08-12 |
rat |
| Veronika Vakhapova, Yael Richter, Tzafra Cohen, Yael Herzog, Amos D Korczy. Safety of phosphatidylserine containing omega-3 fatty acids in non-demented elderly: a double-blind placebo-controlled trial followed by an open-label extension. BMC neurology. vol 11. 2011-11-29. PMID:21711517. |
administration of ps extracted from bovine cortex (bc-ps), which contains high levels of omega-3 long chain polyunsaturated fatty acid (lc-pufa) attached to its backbone, resulted in positive effects on brain functions such as learning and memory. |
2011-11-29 |
2023-08-12 |
cattle |
| Tim Vanmierlo, Kris Rutten, Leonie C van Vark-van der Zee, Silvia Friedrichs, Vincent W Bloks, Arjan Blokland, Frans C Ramaekers, Eric Sijbrands, Harry Steinbusch, Jos Prickaerts, Folkert Kuipers, Dieter Lütjohann, Monique Mulde. Cerebral accumulation of dietary derivable plant sterols does not interfere with memory and anxiety related behavior in Abcg5-/- mice. Plant foods for human nutrition (Dordrecht, Netherlands). vol 66. issue 2. 2011-10-31. PMID:21431910. |
plant sterol accumulation resulted in decreased levels of desmosterol (p<0.01) and 24(s)-hydroxycholesterol (p<0.01) in the hippocampus, the brain region important for learning and memory functions, and increased lanosterol levels (p<0.01) in the cortex. |
2011-10-31 |
2023-08-12 |
mouse |
| Xiao-Ping Chen, Xiang Wang, Jing-Yin Don. Different reaction patterns of dopamine content to prenatal exposure to chlorpyrifos in different periods. Journal of applied toxicology : JAT. vol 31. issue 4. 2011-09-16. PMID:21089160. |
these results suggest that the two key brain regions involved in learning and memory, the cerebral cortex and hippocampus, react differently to cpf exposure in different prenatal periods. |
2011-09-16 |
2023-08-12 |
Not clear |
| Xiao-Rui Cheng, Yong Yang, Wen-Xia Zhou, Yong-Xiang Zhan. Expression of VGLUTs contributes to degeneration and acquisition of learning and memory. Neurobiology of learning and memory. vol 95. issue 3. 2011-08-03. PMID:21295146. |
our results demonstrate that, in the cerebral cortex, protein expression of vglut1, vglut2, vglut3 and syp was decreased in samp8 with age and increased in km mice, which displayed an enhanced capacity for learning and memory. |
2011-08-03 |
2023-08-12 |
mouse |
| Kathy R Magnusson, Brenna L Brim, Siba R Da. Selective Vulnerabilities of N-methyl-D-aspartate (NMDA) Receptors During Brain Aging. Frontiers in aging neuroscience. vol 2. 2011-07-14. PMID:20552049. |
n-methyl-d-aspartate (nmda) receptors are present in high density within the cerebral cortex and hippocampus and play an important role in learning and memory. |
2011-07-14 |
2023-08-12 |
Not clear |
| Yong-Lin Jia, Li-Jun Jing, Jin-Yi Li, Jing-Jing Lu, Rui Han, Shu-Yang Wang, Tao Peng, Yan-Jie Ji. Expression and significance of DSCAM in the cerebral cortex of APP transgenic mice. Neuroscience letters. vol 491. issue 2. 2011-07-05. PMID:21241773. |
we propose that overexpression of dscam in the cerebral cortex might play an important role in the learning and memory defects of app transgenic mice. |
2011-07-05 |
2023-08-12 |
mouse |
| Teresa A Milner, Louisa I Thompson, Gang Wang, Justin A Kievits, Eugene Martin, Ping Zhou, Bruce S McEwen, Donald W Pfaff, Elizabeth M Water. Distribution of estrogen receptor β containing cells in the brains of bacterial artificial chromosome transgenic mice. Brain research. vol 1351. 2011-05-17. PMID:20599828. |
in particular, erbeta-egfp cells were found in autonomic brain regions (i.e., hypothalamic paraventricular nucleus, rostral ventrolateral medulla and nucleus of the solitary tract), in regions associated with anxiety and stress behaviors (i.e., bed nucleus of the stria terminalis, amygdala, periaqueductal gray, raphe and parabrachial nuclei) and in regions involved in learning and memory processes (i.e., basal forebrain, cerebral cortex and hippocampus). |
2011-05-17 |
2023-08-12 |
mouse |
| Dong Liu, Michael Pitta, Jong-Hwan Lee, Balmiki Ray, Debomoy K Lahiri, Katsutoshi Furukawa, Mohamed Mughal, Haiyang Jiang, Julissa Villarreal, Roy G Cutler, Nigel H Greig, Mark P Mattso. The KATP channel activator diazoxide ameliorates amyloid-β and tau pathologies and improves memory in the 3xTgAD mouse model of Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 22. issue 2. 2011-03-09. PMID:20847430. |
3xtgad mice treated with diazoxide for 8 months exhibited improved performance in a learning and memory test, reduced levels of anxiety, decreased accumulation of aβ oligomers and hyperphosphorylated tau in the cortex and hippocampus, and increased cerebral blood flow. |
2011-03-09 |
2023-08-12 |
mouse |
| Reihaneh Hoveida, Hojjatallah Alaei, Shahrbanoo Oryan, Kazem Parivar, Parham Reis. Treadmill running improves spatial memory in an animal model of Alzheimer's disease. Behavioural brain research. vol 216. issue 1. 2011-02-18. PMID:20709113. |
alzheimer's disease (ad) is a progressive neurodegenerative disease that is characterized by a decline in cognitive function and severe neuronal loss in the cerebral cortex and certain subcortical regions of the brain including nucleus basalis magnocellularis (nbm) that play an important role in learning and memory. |
2011-02-18 |
2023-08-12 |
rat |
| Yi Wang, Yi Hou, Jing Dong, Hongde Xu, Jian Gong, Jie Che. Developmental iodine deficiency and hypothyroidism reduce phosphorylation of calcium/calmodulin-dependent kinase II in the rat entorhinal cortex. Biological trace element research. vol 137. issue 3. 2011-01-31. PMID:20054663. |
though the entorhinal cortex (ec) is an important functional structure within the neuronal network responsible for learning and memory, little is known about the effect of hypothyroidism on phosphorylation of camkii in the ec. |
2011-01-31 |
2023-08-12 |
rat |
| P A McCoy, L L McMaho. Sympathetic sprouting in visual cortex stimulated by cholinergic denervation rescues expression of two forms of long-term depression at layer 2/3 synapses. Neuroscience. vol 168. issue 3. 2010-09-21. PMID:20412838. |
cholinergic innervation of hippocampus and cortex is required for some forms of learning and memory. |
2010-09-21 |
2023-08-12 |
Not clear |