| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C L Wellman, D R Sengelau. Cortical neuroanatomical correlates of behavioral deficits produced by lesion of the basal forebrain in rats. Behavioral and neural biology. vol 56. issue 1. 1991-09-12. PMID:1867622. |
the cortical morphological changes observed in the present study following basal forebrain lesion provide further evidence for the importance of ascending cholinergic inputs to the cortex and their role in learning and memory. |
1991-09-12 |
2023-08-11 |
rat |
| T Otto, F Schottler, U Staubli, H Eichenbaum, G Lync. Hippocampus and olfactory discrimination learning: effects of entorhinal cortex lesions on olfactory learning and memory in a successive-cue, go-no-go task. Behavioral neuroscience. vol 105. issue 1. 1991-06-07. PMID:2025384. |
hippocampus and olfactory discrimination learning: effects of entorhinal cortex lesions on olfactory learning and memory in a successive-cue, go-no-go task. |
1991-06-07 |
2023-08-11 |
rat |
| T Otto, F Schottler, U Staubli, H Eichenbaum, G Lync. Hippocampus and olfactory discrimination learning: effects of entorhinal cortex lesions on olfactory learning and memory in a successive-cue, go-no-go task. Behavioral neuroscience. vol 105. issue 1. 1991-06-07. PMID:2025384. |
three experiments assessed the effect of entorhinal cortex lesions on olfactory learning and memory using a successive-cue olfactory discrimination paradigm. |
1991-06-07 |
2023-08-11 |
rat |
| J T Greenamyre, A B Youn. Excitatory amino acids and Alzheimer's disease. Neurobiology of aging. vol 10. issue 5. 1989-12-18. PMID:2554168. |
excitatory amino acids (eaa) such as glutamate and aspartate are major transmitters of the cerebral cortex and hippocampus, and eaa mechanisms appear to play a role in learning and memory. |
1989-12-18 |
2023-08-11 |
Not clear |
| A Toumane, T Durkin, A Marighetto, D Galey, R Jaffar. Differential hippocampal and cortical cholinergic activation during the acquisition, retention, reversal and extinction of a spatial discrimination in an 8-arm radial maze by mice. Behavioural brain research. vol 30. issue 3. 1988-12-06. PMID:3178994. |
possible differentiation of the intervention of cholinergic septohippocampal and magnocellular forebrain (nbm) projections to cortex during learning and memory processes has been investigated directly using mice. |
1988-12-06 |
2023-08-11 |
mouse |
| J T Greenamyre, W F Maragos, R L Albin, J B Penney, A B Youn. Glutamate transmission and toxicity in Alzheimer's disease. Progress in neuro-psychopharmacology & biological psychiatry. vol 12. issue 4. 1988-09-21. PMID:2900537. |
glutamate is the major excitatory transmitter of the cerebral cortex and hippocampus and it appears to have an important role in learning and memory. |
1988-09-21 |
2023-08-11 |
Not clear |
| R Metherate, N Tremblay, R W Dyke. Transient and prolonged effects of acetylcholine on responsiveness of cat somatosensory cortical neurons. Journal of neurophysiology. vol 59. issue 4. 1988-06-27. PMID:2897435. |
this mechanism to alter neuronal responsiveness has many of the characteristics necessary to account for the reorganization observed in somatosensory cortex following alterations in its afferent drive and may be related to some forms of learning and memory. |
1988-06-27 |
2023-08-11 |
cat |
| M W Decke. The effects of aging on hippocampal and cortical projections of the forebrain cholinergic system. Brain research. vol 434. issue 4. 1988-02-17. PMID:3319050. |
it has been proposed that disruption of cholinergic input to the hippocampus and cortex contributes to the learning and memory deficits associated with aging. |
1988-02-17 |
2023-08-11 |
Not clear |
| M W Decke. The effects of aging on hippocampal and cortical projections of the forebrain cholinergic system. Brain research. vol 434. issue 4. 1988-02-17. PMID:3319050. |
thus, investigation of these changes in the dynamic properties of cholinergic input to the hippocampus and cortex during aging may provide clarification of the relationship between cholinergic dysfunction and age-related decline in learning and memory and may also provide a more reasonable rationale for treatment approaches. |
1988-02-17 |
2023-08-11 |
Not clear |
| P J Riekkinen, V Laulumaa, J Sirviö, H Soininen, E L Helkal. Recent progress in the research of Alzheimer's disease. Medical biology. vol 65. issue 2-3. 1987-11-19. PMID:3309490. |
the hippocampus and entorhinal cortex seem to play an important role in learning and memory. |
1987-11-19 |
2023-08-11 |
Not clear |
| I Fukuchi, S Kato, M Nakahiro, S Uchida, R Ishida, H Yoshid. Blockade of cholinergic receptors by an irreversible antagonist, propylbenzilylcholine mustard (PrBCM), in the rat cerebral cortex causes deficits in passive avoidance learning. Brain research. vol 400. issue 1. 1987-03-30. PMID:3028567. |
studies were made on the effects of blockade of muscarinic acetylcholine (mach) receptors in the rat cerebral cortex on learning and memory assessed by performance of a step-through passive avoidance task. |
1987-03-30 |
2023-08-11 |
rat |
| I Fukuchi, S Kato, M Nakahiro, S Uchida, R Ishida, H Yoshid. Blockade of cholinergic receptors by an irreversible antagonist, propylbenzilylcholine mustard (PrBCM), in the rat cerebral cortex causes deficits in passive avoidance learning. Brain research. vol 400. issue 1. 1987-03-30. PMID:3028567. |
these results confirm the notion that cholinergic neurotransmission in the cerebral cortex, especially the frontoparietal cortex, is important in learning and memory. |
1987-03-30 |
2023-08-11 |
rat |
| I Fukuchi, S Kato, M Nakahiro, S Uchida, R Ishida, H Yoshid. Blockade of cholinergic receptors by an irreversible antagonist, propylbenzilylcholine mustard (PrBCM), in the rat cerebral cortex causes deficits in passive avoidance learning. Brain research. vol 400. issue 1. 1987-03-30. PMID:3028567. |
the effects of injection of prbcm (22.5 x 4 micrograms) into the frontoparietal cortex on 3 postulated phases of the learning and memory process (i.e. |
1987-03-30 |
2023-08-11 |
rat |
| E L Bailey, D H Overstreet, A D Crocke. Effects of intrahippocampal injections of the cholinergic neurotoxin AF64A on open-field activity and avoidance learning in the rat. Behavioral and neural biology. vol 45. issue 3. 1986-06-27. PMID:3718391. |
these findings indicate that lesioning of cholinergic terminals in the hippocampus and/or cerebral cortex with af64a leads to long-term deficits in learning and memory as well as increases in open-field activity. |
1986-06-27 |
2023-08-11 |
rat |
| A W Buffer. Learning and memory in baboons with bilateral lesions of frontal or inferotemporal cortex. Nature. vol 214. issue 5092. 1967-12-26. PMID:4964235. |
learning and memory in baboons with bilateral lesions of frontal or inferotemporal cortex. |
1967-12-26 |
2023-08-11 |
Not clear |