| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M G Bixel, M Krauss, Y Liu, M L Bolognesi, M Rosini, I S Mellor, P N Usherwood, C Melchiorre, K Nakanishi, F Huch. Structure-activity relationship and site of binding of polyamine derivatives at the nicotinic acetylcholine receptor. European journal of biochemistry. vol 267. issue 1. 2000-02-15. PMID:10601857. |
to elucidate the site of phtx binding, a photolabile, radioactive phtx derivative was photocross-linked to the nachr in its closed channel conformation resulting in labeling yields for the two alpha and the beta, gamma and delta subunits of 10.4, 11.1, 4.0 and 7.4%, respectively. |
2000-02-15 |
2023-08-12 |
Not clear |
| A M Caccuri, G Antonini, P G Board, M W Parker, M Nicotra, M Lo Bello, G Federici, G Ricc. Proton release on binding of glutathione to alpha, Mu and Delta class glutathione transferases. The Biochemical journal. vol 344 Pt 2. 2000-02-11. PMID:10567224. |
the delta gst, which is closely related to the mammalian theta class enzymes and is distantly related to alpha and mu gsts in the evolutionary pathway, might display a different activation mechanism for gsh. |
2000-02-11 |
2023-08-12 |
Not clear |
| J Weber-Arden, O M Wilbert, D Kabelitz, B Arde. V delta repertoire during thymic ontogeny suggests three novel waves of gamma delta TCR expression. Journal of immunology (Baltimore, Md. : 1950). vol 164. issue 2. 2000-02-10. PMID:10623850. |
neonatal delta-chain transcripts used a second wave of diverse v alpha gene segments that are exclusively located in the delta locus-proximal gene cluster of intermingled single members of different v alpha subfamilies. |
2000-02-10 |
2023-08-12 |
Not clear |
| M J Yi, T H Kim, S J Lee, C K Cho, I H Bae, Y S Le. Radiation augments a sequential program of differentiation in PKC inhibitor- pretreated mouse epidermal cells. Journal of radiation research. vol 40. issue 3. 2000-02-04. PMID:10641489. |
radiation also induced pkc alpha expression in sts pretreated cells, independent of ca(2+)-shift, as well as altered expressions of pkc delta and -eta, while expressions of pkc alpha, -delta, -epsilon, and -eta were enhanced in v-rasha transformed cells. |
2000-02-04 |
2023-08-12 |
mouse |
| E Kocsis, M Kessel, E DeMoll, D A Graham. Structure of the Ni/Fe-S protein subcomponent of the acetyl-CoA decarbonylase/synthase complex from Methanosarcina thermophila at 26-A resolution. Journal of structural biology. vol 128. issue 2. 2000-02-02. PMID:10600570. |
the complex is composed of five different subunits, with a probable stoichiometry of alpha(8)beta(8)gamma(8)delta(8)epsilon(8). |
2000-02-02 |
2023-08-12 |
Not clear |
| S J Diede, D E Gottschlin. Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases alpha and delta. Cell. vol 99. issue 7. 2000-02-01. PMID:10619426. |
telomerase-mediated telomere addition in vivo requires dna primase and dna polymerases alpha and delta. |
2000-02-01 |
2023-08-12 |
Not clear |
| S J Diede, D E Gottschlin. Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases alpha and delta. Cell. vol 99. issue 7. 2000-02-01. PMID:10619426. |
telomere addition was detected in m phase arrested cells, which permitted us to determine that the essential dna polymerases alpha and delta and dna primase were required. |
2000-02-01 |
2023-08-12 |
Not clear |
| A Chadha, L G Dawson, P G Jenner, S Dut. Effect of unilateral 6-hydroxydopamine lesions of the nigrostriatal pathway on GABA(A) receptor subunit gene expression in the rodent basal ganglia and thalamus. Neuroscience. vol 95. issue 1. 2000-01-31. PMID:10619468. |
this study examined whether changes in expression of the genes encoding known gaba(a) receptor subunits (alpha(1-4), beta(1-3), gamma(1-3) and delta) could account for this receptor plasticity using a rodent model of parkinson's disease with a 6-hydroxydopamine-induced nigrostriatal lesion. |
2000-01-31 |
2023-08-12 |
Not clear |
| X J Chen, G D Clark-Walke. Alpha and beta subunits of F1-ATPase are required for survival of petite mutants in Saccharomyces cerevisiae. Molecular & general genetics : MGG. vol 262. issue 4-5. 2000-01-31. PMID:10628876. |
inactivation of either the alpha or beta subunit, but not the gamma, delta, or epsilon subunit of f1, renders cells petite-negative. |
2000-01-31 |
2023-08-12 |
Not clear |
| G L Mendes, A R Santos, A Malheiros, V C Filho, R A Yunes, J B Calixt. Assessment of mechanisms involved in antinociception caused by sesquiterpene polygodial. The Journal of pharmacology and experimental therapeutics. vol 292. issue 1. 2000-01-27. PMID:10604944. |
the mechanism by which polygodial produces antinociception seems likely to involve an interaction with the opioid system, mainly kappa and delta subtypes, depend on the activation of g(i/o) protein sensitive to pertussis toxin, alpha(1)-adrenoceptors, and the serotoninergic system. |
2000-01-27 |
2023-08-12 |
mouse |
| D L Burgess, C F Davis, L A Gefrides, J L Noebel. Identification of three novel Ca(2+) channel gamma subunit genes reveals molecular diversification by tandem and chromosome duplication. Genome research. vol 9. issue 12. 2000-01-27. PMID:10613843. |
ten paralogous genes have been identified that encode isoforms of the alpha(1) subunit, four that encode beta subunits, and three that encode alpha(2)delta subunits. |
2000-01-27 |
2023-08-12 |
mouse |
| T Lehne. Immunopathogenesis of Behçet's disease. Annales de medecine interne. vol 150. issue 6. 2000-01-19. PMID:10615534. |
microbial infection induced stress upregulates hsp65 and mica gene product which stimulate gamma delta and alpha beta t cell receptor positive cells, to generate effector and suppressor t cells (fig. |
2000-01-19 |
2023-08-12 |
human |
| M Filizola, L Laakkonen, G H Loe. 3D modeling, ligand binding and activation studies of the cloned mouse delta, mu; and kappa opioid receptors. Protein engineering. vol 12. issue 11. 2000-01-18. PMID:10585498. |
refined 3d models of the transmembrane domains of the cloned delta, mu and kappa opioid receptors belonging to the superfamily of g-protein coupled receptors (gpcrs) were constructed from a multiple sequence alignment using the alpha carbon template of rhodopsin recently reported. |
2000-01-18 |
2023-08-12 |
mouse |
| I Corre, H Baumann, S Hermoue. Regulation by Gi2 proteins of v-fms-induced proliferation and transformation via Src-kinase and STAT3. Oncogene. vol 18. issue 46. 2000-01-10. PMID:10597233. |
we found that tyrosine phosphorylation of stat3, also activated by csf-1r/v-fms, was inhibited in alpha i2-g204a/v-fms cells; in addition, expression of an 85 kda, c-terminal truncated form of stat3 (stat3 delta) was constitutively increased. |
2000-01-10 |
2023-08-12 |
Not clear |
| S B Smith, H C Ee, J R Conners, M S Germa. Paired-homeodomain transcription factor PAX4 acts as a transcriptional repressor in early pancreatic development. Molecular and cellular biology. vol 19. issue 12. 2000-01-06. PMID:10567552. |
in the absence of pax4, the numbers of insulin-producing beta cells and somatostatin-producing delta cells are drastically reduced, while the numbers of glucagon-producing alpha cells are increased. |
2000-01-06 |
2023-08-12 |
mouse |
| A C Hausrath, G Grüber, B W Matthews, R A Capald. Structural features of the gamma subunit of the Escherichia coli F(1) ATPase revealed by a 4.4-A resolution map obtained by x-ray crystallography. Proceedings of the National Academy of Sciences of the United States of America. vol 96. issue 24. 2000-01-06. PMID:10570135. |
the bacterial f(1) consists of five subunits with stoichiometry alpha(3), beta(3), gamma, delta, and epsilon. |
2000-01-06 |
2023-08-12 |
rat |
| K Ohshima, J Suzumiya, M Sugihara, M Kanda, K Shimazaki, C Kawasaki, S Haraoka, M Kikuch. Clinical, immunohistochemical and phenotypic features of aggressive nodal cytotoxic lymphomas, including alpha/beta, gamma/delta T-cell and natural killer cell types. Virchows Archiv : an international journal of pathology. vol 435. issue 2. 2000-01-06. PMID:10599306. |
cytotoxic cells include natural killer (nk) cells and cytotoxic alpha beta and gamma delta t lymphocytes (ctls). |
2000-01-06 |
2023-08-12 |
Not clear |
| K Ohshima, J Suzumiya, M Sugihara, M Kanda, K Shimazaki, C Kawasaki, S Haraoka, M Kikuch. Clinical, immunohistochemical and phenotypic features of aggressive nodal cytotoxic lymphomas, including alpha/beta, gamma/delta T-cell and natural killer cell types. Virchows Archiv : an international journal of pathology. vol 435. issue 2. 2000-01-06. PMID:10599306. |
phenotypically and genotypically, four cases showed alpha beta t cell type [cd2+, cd3+, t-cell receptor (tcr)-delta-1-, beta f1+, and tcr gene rearrangement], two cases showed gamma delta cell type [cd2+, cd3+, t-cell receptor (tcr) delta-1+, beta f1-, and tcr gene rearrangement], and one case showed nk cell type [cd2+, cd3-, cd56+, t-cell receptor (tcr) delta-1-, beta f1-, and tcr gene germline]. |
2000-01-06 |
2023-08-12 |
Not clear |
| S Salvadori, R Guerrini, G Balboni, C Bianchi, S D Bryant, P S Cooper, L H Lazaru. Further studies on the Dmt-Tic pharmacophore: hydrophobic substituents at the C-terminus endow delta antagonists to manifest mu agonism or mu antagonism. Journal of medicinal chemistry. vol 42. issue 24. 2000-01-04. PMID:10585210. |
h-dmt-betahtic-oh (methylene bridge between c(alpha) of tic and carboxylate function) yielded a biostable peptide with high delta affinity (k(i) = 0.85 nm) and delta antagonism (pa(2) = 8.85) without mu bioactivity. |
2000-01-04 |
2023-08-12 |
Not clear |
| K Tamura, R L Rice, P Wipf, J S Laz. Dual G1 and G2/M phase inhibition by SC-alpha alpha delta 9, a combinatorially derived Cdc25 phosphatase inhibitor. Oncogene. vol 18. issue 50. 2000-01-04. PMID:10597298. |
dual g1 and g2/m phase inhibition by sc-alpha alpha delta 9, a combinatorially derived cdc25 phosphatase inhibitor. |
2000-01-04 |
2023-08-12 |
Not clear |