Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
J K Chilton, A W Stoke. Expression of receptor protein tyrosine phosphatases in embryonic chick spinal cord. Molecular and cellular neurosciences. vol 16. issue 4. 2001-03-08. PMID:11085882. |
cryp alpha 2, rptp psi, and rptp delta are neuronally expressed elsewhere in the cord, but not in ventral motorneurons, whereas rptp mu is unique in being restricted to capillaries. |
2001-03-08 |
2023-08-12 |
chicken |
G Wagner, M Haukka, J J da Silva, A J Pombeiro, V Y Kukushki. [2 + 3] cycloaddition of nitrones to platinum-bound organonitriles: effect of metal oxidation state and of nitrile substituent. Inorganic chemistry. vol 40. issue 2. 2001-03-01. PMID:11170530. |
all prepared compounds were characterized by elemental analyses, fab mass spectrometry, and ir and 1h, 13c(1h), and 195pt (metal complexes) nmr spectroscopies; x-ray structure determination of the first (delta 4-1,2,4-oxadiazoline)pt(ii) complexes was performed for (s,s)/(r,r)-rac-[ptcl2(n=c(me)o-n(me)-c(h)ph)2] (1a) (a = 9.3562(4), b = 9.8046(3), c = 13.1146(5) a; alpha = 76.155(2), beta = 83.421(2), gamma = 73.285(2) degrees; v = 1117.39(7) a3; triclinic, p1, z = 2), (r,s)-meso-[ptcl2(n=c(ph)o-n(me)-c(h)ph)2] (2a) (a = 8.9689(9), b = 9.1365(5), c = 10.1846(10) a; alpha = 64.328(6), beta = 72.532(4), gamma = 67.744(6) degrees; v = 686.82(11) a3; triclinic, p1, z = 1), (s,s)/(r,r)-rac-[ptcl2(n=c(me)o-n(me)-c(h)(p-c6h4me))2] (3a) (a = 11.6378(2), b = 19.0767(7), c = 11.5782(4) a; beta = 111.062(2) degrees; v = 2398.76(13) a3; monoclinic, p2(1)/c, z = 4), and (s,s)/(r,r)-rac-[ptcl2(n=c(me)o-n(ch2ph)-c(h)ph2] (5a) (a = 10.664(2), b = 10.879(2), c = 14.388(3) a; alpha = 73.11(3), beta = 78.30(3), gamma = 88.88(3) degrees; v = 1562.6(6) a3; triclinic, p1, z = 2). |
2001-03-01 |
2023-08-12 |
Not clear |
M J Field, J Hughes, L Sing. Further evidence for the role of the alpha(2)delta subunit of voltage dependent calcium channels in models of neuropathic pain. British journal of pharmacology. vol 131. issue 2. 2001-02-22. PMID:10991921. |
further evidence for the role of the alpha(2)delta subunit of voltage dependent calcium channels in models of neuropathic pain. |
2001-02-22 |
2023-08-12 |
rat |
M J Field, J Hughes, L Sing. Further evidence for the role of the alpha(2)delta subunit of voltage dependent calcium channels in models of neuropathic pain. British journal of pharmacology. vol 131. issue 2. 2001-02-22. PMID:10991921. |
recent studies have demonstrated that gabapentin selectively interacts with the alpha(2)delta subunit of voltage dependent calcium channels (vdccs) which may be important in its mechanism of action. |
2001-02-22 |
2023-08-12 |
rat |
M J Field, J Hughes, L Sing. Further evidence for the role of the alpha(2)delta subunit of voltage dependent calcium channels in models of neuropathic pain. British journal of pharmacology. vol 131. issue 2. 2001-02-22. PMID:10991921. |
previous studies have identified a gabapentin analogue, 3-methyl gabapentin, that stereoselectively interacts with the alpha(2)delta subunit of vdccs. |
2001-02-22 |
2023-08-12 |
rat |
M J Field, J Hughes, L Sing. Further evidence for the role of the alpha(2)delta subunit of voltage dependent calcium channels in models of neuropathic pain. British journal of pharmacology. vol 131. issue 2. 2001-02-22. PMID:10991921. |
thus, whilst (1s, 3r) 3-methyl gabapentin binds to the alpha(2)delta protein with high affinity (ic(50)=42 nm), the corresponding (1r,3r) isomer is 300 times weaker (bryans et al., 1998: j. med. |
2001-02-22 |
2023-08-12 |
rat |
M J Field, J Hughes, L Sing. Further evidence for the role of the alpha(2)delta subunit of voltage dependent calcium channels in models of neuropathic pain. British journal of pharmacology. vol 131. issue 2. 2001-02-22. PMID:10991921. |
the present study examines the activity of diastereoisomers of 3-methyl gabapentin in two rat models of neuropathic pain to assess the importance of an interaction with the alpha(2)delta subunit of vdccs. |
2001-02-22 |
2023-08-12 |
rat |
M J Field, J Hughes, L Sing. Further evidence for the role of the alpha(2)delta subunit of voltage dependent calcium channels in models of neuropathic pain. British journal of pharmacology. vol 131. issue 2. 2001-02-22. PMID:10991921. |
it is concluded that these data further support the hypothesis that the alpha(2)delta subunit of vdccs plays an important role in the maintenance of mechanical hypersensitivity in models of neuropathic pain. |
2001-02-22 |
2023-08-12 |
rat |
H Jing, M Takigaw. Topographic analysis of dimension estimates of EEG and filtered rhythms in epileptic patients with complex partial seizures. Biological cybernetics. vol 83. issue 5. 2001-02-15. PMID:11073203. |
the delta (0.5-4 hz), theta (4-8 hz), alpha (8-13 hz), beta (13-30 hz) and gamma (30-40 hz) components were obtained and considered as signals from the cortex. |
2001-02-15 |
2023-08-12 |
human |
R Kompass, R Hüfner, E Schröger, C Kaernbach, H G Geissle. Alternative perceptual states 'apparent motion' and 'perceived simultaneity' lead to differences of induced EEG rhythms. International journal of psychophysiology : official journal of the International Organization of Psychophysiology. vol 38. issue 3. 2001-02-15. PMID:11102666. |
in addition, a small overall increase in alpha power at 12-13 hz and a decrease in delta power below 3.5 hz during perceived motion were found. |
2001-02-15 |
2023-08-12 |
human |
C Schulz, P Mavrogiorgou, A Schröter, U Hegerl, G Jucke. Lithium-induced EEG changes in patients with affective disorders. Neuropsychobiology. vol 42 Suppl 1. 2001-02-08. PMID:11093069. |
we found (1) an increase in relative power in both delta and theta band which was related to the lithium plasma level, (2) a decrease in relative alpha power especially at occipital leads and (3) a reduction of the dominant alpha frequency. |
2001-02-08 |
2023-08-12 |
Not clear |
B O Porter, P Scibelli, T R Male. Control of T cell development in vivo by subdomains within the IL-7 receptor alpha-chain cytoplasmic tail. Journal of immunology (Baltimore, Md. : 1950). vol 166. issue 1. 2001-02-08. PMID:11123301. |
in contrast, the functional differentiation of tcr alpha beta cells and the development of tcr gamma delta cells are partially independent of the t domain. |
2001-02-08 |
2023-08-12 |
mouse |
A Reichlin, Y Hu, E Meffre, H Nagaoka, S Gong, M Kraus, K Rajewsky, M C Nussenzwei. B cell development is arrested at the immature B cell stage in mice carrying a mutation in the cytoplasmic domain of immunoglobulin beta. The Journal of experimental medicine. vol 193. issue 1. 2001-02-08. PMID:11136817. |
to determine the function of ig beta, we produced mice that carry a deletion of the cytoplasmic domain of ig beta (ig beta delta c mice) and compared them to mice that carry a similar mutation in ig alpha (mb1 delta c, herein referred to as ig alpha delta c mice). |
2001-02-08 |
2023-08-12 |
mouse |
A Reichlin, Y Hu, E Meffre, H Nagaoka, S Gong, M Kraus, K Rajewsky, M C Nussenzwei. B cell development is arrested at the immature B cell stage in mice carrying a mutation in the cytoplasmic domain of immunoglobulin beta. The Journal of experimental medicine. vol 193. issue 1. 2001-02-08. PMID:11136817. |
ig beta delta c mice differ from ig alpha delta c mice in that they show little impairment in early b cell development and they produce immature b cells that respond normally to bcr cross-linking as determined by ca(2+) flux. |
2001-02-08 |
2023-08-12 |
mouse |
C K Thodeti, C K Nielsen, S Paruchuri, C Larsson, A Sjölande. The epsilon isoform of protein kinase C is involved in regulation of the LTD(4)-induced calcium signal in human intestinal epithelial cells. Experimental cell research. vol 262. issue 2. 2001-02-08. PMID:11139333. |
the pkc inhibitor gf109203x at 30 microm but not 2 microm significantly impaired the ltd(4)-induced ca(2+) signal, indicating that the response involves a novel pkc isoform, such as delta or epsilon, but not alpha. |
2001-02-08 |
2023-08-12 |
human |
Y Inai, T Oshikawa, M Yamashita, T Hirabayashi, T Hirak. Structural and conformational properties of (Z)-beta-(1-naphthyl)- dehydroalanine residue. Biopolymers. vol 58. issue 1. 2001-02-02. PMID:11072225. |
the bond lengths and bond angles of the delta(z)nap residue, characterized by a sp(2) hybridized c(alpha) atom, did not differ from those of other dehydroresidues such as delta(z) phe, delta(z) leu, and deltaval essentially. |
2001-02-02 |
2023-08-12 |
Not clear |
P Taylor, S Malanz, B E Molles, H Osaka, I Tsigeln. Subunit interface selective toxins as probes of nicotinic acetylcholine receptor structure. Pflugers Archiv : European journal of physiology. vol 440. issue 5 Suppl. 2001-02-01. PMID:11005635. |
by interchanging residues on the gamma and delta subunits through mutagenesis, and ascertaining how they interact with the alpha subunit, determinants forming the binding sites can be delineated. |
2001-02-01 |
2023-08-12 |
Not clear |
D Braida, F Ottonello, M Sal. Eptastigmine restores the aged rat's normal cortical spectral power pattern. Pharmacological research. vol 42. issue 5. 2001-02-01. PMID:11023715. |
we studied the ability of eptastigmine, a second-generation acetylcholinesterase inhibitor (achei), to reverse the age-related increase of electroencephalogram (eeg) mean cortical spectral power in slow-wave delta activity and decrease in fast-wave alpha and beta activity. |
2001-02-01 |
2023-08-12 |
rat |
D Braida, F Ottonello, M Sal. Eptastigmine restores the aged rat's normal cortical spectral power pattern. Pharmacological research. vol 42. issue 5. 2001-02-01. PMID:11023715. |
the relative basal spectral power profile evaluated for 50 min of the old (27-30 months) in comparison to young (4-6 months) awake rats was consistently different, showing a significant increase in delta(0.2-4.0 hz) frequency and a significant decrease of alpha(8.2-13.0 hz) and beta(13.2-25.0) bands. |
2001-02-01 |
2023-08-12 |
rat |
D Braida, F Ottonello, M Sal. Eptastigmine restores the aged rat's normal cortical spectral power pattern. Pharmacological research. vol 42. issue 5. 2001-02-01. PMID:11023715. |
when 0.5, 1, 2, 4 mg kg(-1)of eptastigmine were administered orally as single increasing doses for old and young rats 2 h prior to the eeg recordings, lasting 2 h, the relative mean spectral power difference (delta%) showed a linear log dose-related decrease in delta activity and a progressive increase in alpha and beta activity in old rats. |
2001-02-01 |
2023-08-12 |
rat |