| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| X A Alvarez, V R Lombardi, L Corzo, P Pérez, V Pichel, M Laredo, A Hernández, F Freixeiro, C Sampedro, R Lorenzo, M Alcaraz, M Windisch, R Cacabelo. Oral Cerebrolysin enhances brain alpha activity and improves cognitive performance in elderly control subjects. Journal of neural transmission. Supplementum. vol 59. 2000-12-22. PMID:10961443. |
these data indicate that cerebrolysin potentiates brain alpha activity, reduces slow eeg delta frequencies and improves memory performance in healthy elderly humans, suggesting that this compound activates cerebral mechanisms related to attention and memory processes. |
2000-12-22 |
2023-08-12 |
human |
| I Q Fan, B Chen, J D Mars. Transcriptional regulation of L-type calcium channel expression in cardiac myocytes. Journal of molecular and cellular cardiology. vol 32. issue 10. 2000-12-07. PMID:11013128. |
although post-translational regulation of its subunits by protein kinase a (pka) has been widely reported, little is known about molecular processes that regulate expression of calcium channel subunits (alpha(1c), alpha(2)- delta, and beta(2a)subunits). |
2000-12-07 |
2023-08-12 |
rat |
| I Q Fan, B Chen, J D Mars. Transcriptional regulation of L-type calcium channel expression in cardiac myocytes. Journal of molecular and cellular cardiology. vol 32. issue 10. 2000-12-07. PMID:11013128. |
in isoproterenol (10(-7)m)-treated myocytes, transcription of genes encoding the alpha(1c), alpha(2)- delta, and beta(2a)subunits was enhanced. |
2000-12-07 |
2023-08-12 |
rat |
| I Q Fan, B Chen, J D Mars. Transcriptional regulation of L-type calcium channel expression in cardiac myocytes. Journal of molecular and cellular cardiology. vol 32. issue 10. 2000-12-07. PMID:11013128. |
the increases in transcription initiation rate for alpha(1c), alpha(2)- delta, and beta(2a)subunits genes were 404%, 367%, and 240% of control, respectively. |
2000-12-07 |
2023-08-12 |
rat |
| T S Tengku-Muhammad, T R Hughes, H Ranki, A Cryer, D P Ramj. Differential regulation of macrophage CCAAT-enhancer binding protein isoforms by lipopolysaccharide and cytokines. Cytokine. vol 12. issue 9. 2000-11-30. PMID:10976009. |
exposure of the cells to lps, il-1, ifn-gamma and tnf-alpha produced a reduction of c/ebp alpha mrna levels and a corresponding increase in the expression of c/ebp beta and c/ebp delta. |
2000-11-30 |
2023-08-12 |
Not clear |
| J M González, R Simó, R Massana, J S Covert, E O Casamayor, C Pedrós-Alió, M A Mora. Bacterial community structure associated with a dimethylsulfoniopropionate-producing North Atlantic algal bloom. Applied and environmental microbiology. vol 66. issue 10. 2000-11-30. PMID:11010865. |
three other abundant bacterial phylotypes (representing a cyanobacterium and two members of the alpha proteobacteria) were primarily associated with chlorophyll-rich surface waters of the bloom (0 to 50 m), while two others (representing cytophagales and delta proteobacteria) were primarily found in deeper waters (200 to 500 m). |
2000-11-30 |
2023-08-12 |
Not clear |
| D McHugh, E M Sharp, T Scheuer, W A Catteral. Inhibition of cardiac L-type calcium channels by protein kinase C phosphorylation of two sites in the N-terminal domain. Proceedings of the National Academy of Sciences of the United States of America. vol 97. issue 22. 2000-11-28. PMID:11035786. |
using the patch-clamp technique, we found that pkc activation by 4-alpha-phorbol 12-myristate 13-acetate (pma) or rac-1-oleyl-2-acetylglycerol (oag) caused a substantial reduction in ba(2+) current through ca(v)1.2 channels composed of alpha(1)1.2, beta(1b), and alpha(2)delta(1) subunits expressed in tsa-201 cells. |
2000-11-28 |
2023-08-12 |
Not clear |
| Y Mizushina, S Kamisuki, T Mizuno, M Takemura, H Asahara, S Linn, T Yamaguchi, A Matsukage, F Hanaoka, S Yoshida, M Saneyoshi, F Sugawara, K Sakaguch. Dehydroaltenusin, a mammalian DNA polymerase alpha inhibitor. The Journal of biological chemistry. vol 275. issue 43. 2000-11-24. PMID:10942777. |
dehydroaltenusin did not influence the activities of the other replicative dna polymerases, such as delta and epsilon; it also showed no effect even on the pol alpha activity from another vertebrate (fish) or plant species. |
2000-11-24 |
2023-08-12 |
mouse |
| Y H Ko, J Hullihen, S Hong, P L Pederse. Mitochondrial F(0)F(1) ATP synthase. Subunit regions on the F1 motor shielded by F(0), Functional significance, and evidence for an involvement of the unique F(0) subunit F(6). The Journal of biological chemistry. vol 275. issue 42. 2000-11-20. PMID:10887193. |
second, at the bottom of f(1) within f(0)f(1), the n-terminal region of the single delta subunit and the c-terminal regions of all three alpha subunits are shielded also by f(0). |
2000-11-20 |
2023-08-12 |
Not clear |
| J Polich, A Ilan, J S Poceta, M M Mitler, D F Dark. Neuroelectric assessment of HIV: EEG, ERP, and viral load. International journal of psychophysiology : official journal of the International Organization of Psychophysiology. vol 38. issue 1. 2000-11-17. PMID:11027797. |
spectral analysis demonstrated that hiv patients evinced greater pre-stimulus delta power over frontal areas compared to control subjects, and less post-stimulus spectral power for the delta, theta, and alpha bands over the central/parietal areas. |
2000-11-17 |
2023-08-12 |
human |
| H U Keller, I P Hunziker, B Sordat, V Niggli, J Srok. Protein kinase C isoforms involved in regulation of cell shape and locomotion of human fibrosarcoma HT1080 cells. International journal of cancer. vol 88. issue 2. 2000-11-15. PMID:11004668. |
ro 31-8220 alone induced a moderate down-regulation of pkc isoforms alpha and delta, but it also inhibited the more pronounced down-regulation of these isoforms by pma. |
2000-11-15 |
2023-08-12 |
human |
| E Meacci, C Donati, F Cencetti, E Romiti, P Brun. Permissive role of protein kinase C alpha but not protein kinase C delta in sphingosine 1-phosphate-induced Rho A activation in C2C12 myoblasts. FEBS letters. vol 482. issue 1-2. 2000-11-08. PMID:11018530. |
permissive role of protein kinase c alpha but not protein kinase c delta in sphingosine 1-phosphate-induced rho a activation in c2c12 myoblasts. |
2000-11-08 |
2023-08-12 |
Not clear |
| E Meacci, C Donati, F Cencetti, E Romiti, P Brun. Permissive role of protein kinase C alpha but not protein kinase C delta in sphingosine 1-phosphate-induced Rho A activation in C2C12 myoblasts. FEBS letters. vol 482. issue 1-2. 2000-11-08. PMID:11018530. |
conversely rottlerin, a selective inhibitor of pkc delta, was without effect, demonstrating that spp signaling to rho a involves pkc alpha but not pkc delta activation. |
2000-11-08 |
2023-08-12 |
Not clear |
| S Potter, M D Mitchell, W R Hansen, K W Marvi. NF-IL6 and CRE elements principally account for both basal and interleukin-1 beta-induced transcriptional activity of the proximal 528bp of the PGHS-2 promoter in amnion-derived AV3 cells: evidence for involvement of C/EBP beta. Molecular human reproduction. vol 6. issue 9. 2000-11-07. PMID:10956548. |
to a lesser extent c/ebp alpha and delta also interacted with the nf-il6 site. |
2000-11-07 |
2023-08-12 |
cat |
| R S Gupt. The natural evolutionary relationships among prokaryotes. Critical reviews in microbiology. vol 26. issue 2. 2000-11-03. PMID:10890353. |
based on this new proposal, it is now possible to logically deduce the branching order of different prokaryotic taxa from the common ancestor, which is as follows: gram-positive bacteria (low g + c) (<=> archaebacteria) => gram-positive bacteria (high g + c) (<=> archaebacteria)=> deinococcus-thermus => green nonsulfur bacteria => cyanobacteria => spirochetes => chlamydia- cytophaga-green sulfur bacteria => proteobacteria-1 (epsilon, delta)=> proteobacteria-2 (alpha) => proteobacteria-3 (beta) => proteobacteria-4 (gamma). |
2000-11-03 |
2023-08-12 |
Not clear |
| M Låg, E Skarpen, B A van Rozendaal, H P Haagsman, H S Huitfeldt, E V Thrane, P E Schwarz. Cell-specific expression of CCAAT/enhancer-binding protein delta (C/EBP delta) in epithelial lung cells. Experimental lung research. vol 26. issue 5. 2000-11-02. PMID:10914335. |
in epithelial lung cells the c/ebp alpha isoform seems to play a role in the regulation of surfactant proteins (sp) and clara cell specific protein (ccsp), whereas the roles of c/ebp beta and c/ebp delta are unclear. |
2000-11-02 |
2023-08-12 |
Not clear |
| R S Gupt. The phylogeny of proteobacteria: relationships to other eubacterial phyla and eukaryotes. FEMS microbiology reviews. vol 24. issue 4. 2000-10-18. PMID:10978543. |
based on signature sequences that are present in different proteins it is now possible to infer that the various eubacterial phyla evolved from a common ancestor in the following order: low-g+c gram-positive-->high-g+c gram-positive-->deinococcus-thermus (green nonsulfur bacteria)-->cyanobacteria-->spirochetes-->chlamydia-cytophaga-aquifex -green sulfur bacteria-->proteobacteria-1 (epsilon and delta)-->proteobacteria-2 (alpha)-->proteobacteria-3 (beta)-->proteobacteria-4 (gamma). |
2000-10-18 |
2023-08-12 |
Not clear |
| Farzana Karim, Sandra C Roeri. Differential effects of antisense oligodeoxynucleotides directed against g(zalpha) and g(oalpha) on antinociception produced by spinal opioid and alpha(2) adrenergic receptor agonists. Pain. vol 87. issue 2. 2000-10-11. PMID:10924811. |
uk14, 304 (alpha(2) adrenergic receptor agonist) and [d-pen(2), d-pen(5)] enkephalin (dpdpe) (delta opioid receptor agonist), whereas it failed to attenuate i.t. |
2000-10-11 |
2023-08-12 |
mouse |
| Farzana Karim, Sandra C Roeri. Differential effects of antisense oligodeoxynucleotides directed against g(zalpha) and g(oalpha) on antinociception produced by spinal opioid and alpha(2) adrenergic receptor agonists. Pain. vol 87. issue 2. 2000-10-11. PMID:10924811. |
these results suggest that spinal g(o)alpha mediates antinociception produced by both clonidine and morphine while g(zalpha) mediates alpha(2) adrenergic and delta opioid receptor mediated antinociception, but not antinociception produced by mu or kappa opioid agonists. |
2000-10-11 |
2023-08-12 |
mouse |
| P Wang, M Malkovsk. Different roles of the CD2 and LFA-1 T-cell co-receptors for regulating cytotoxic, proliferative, and cytokine responses of human V gamma 9/V delta 2 T cells. Molecular medicine (Cambridge, Mass.). vol 6. issue 3. 2000-10-06. PMID:10965495. |
human v gamma 9/v delta 2 t lymphocytes recognize nonpeptidic antigens in a manner distinct from the classical antigen recognition by alpha beta t cells. |
2000-10-06 |
2023-08-12 |
human |