| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marie Deen, Hanne D Hansen, Anders Hougaard, Sofi da Cunha-Bang, Martin Nørgaard, Claus Svarer, Sune H Keller, Carsten Thomsen, Messoud Ashina, Gitte M Knudse. Low 5-HT Cephalalgia : an international journal of headache. vol 38. issue 3. 2019-01-28. PMID:28730894. |
low 5-ht background the pathophysiology of migraine may involve dysfunction of serotonergic signaling. |
2019-01-28 |
2023-08-13 |
Not clear |
| Beatrice Sandner, Radhika Puttagunta, Melanie Motsch, Frank Bradke, Jörg Ruschel, Armin Blesch, Norbert Weidne. Systemic epothilone D improves hindlimb function after spinal cord contusion injury in rats. Experimental neurology. vol 306. 2019-01-28. PMID:29408734. |
moreover, formation of laminin positive fibrotic scar tissue and 5-ht positive serotonergic fiber length caudal to the lesion site were not altered after treatment with epo d. these findings recapitulate a functional benefit after systemic administration of a microtubule-stabilizing drug in rat contusion sci. |
2019-01-28 |
2023-08-13 |
rat |
| E L Gibso. Tryptophan supplementation and serotonin function: genetic variations in behavioural effects. The Proceedings of the Nutrition Society. vol 77. issue 2. 2019-01-16. PMID:29368666. |
moreover, understanding of genotypes involved in regulation of serotonin raises questions over the generalisability of trp effects on behaviour across individuals with varied serotonergic genotypes. |
2019-01-16 |
2023-08-13 |
Not clear |
| Benjamin Laliberte, Omayma A Kish. Serotonin Syndrome in a Pediatric Patient After Vilazodone Ingestion. Pediatric emergency care. vol 34. issue 12. 2019-01-11. PMID:28350718. |
selective serotonin reuptake inhibitors may precipitate ss, particularly in combination with other drugs that possess serotonergic activity. |
2019-01-11 |
2023-08-13 |
Not clear |
| S D Dolzani, M V Baratta, J M Moss, N L Leslie, S G Tilden, A T Sørensen, L R Watkins, Y Lin, S F Maie. Inhibition of a Descending Prefrontal Circuit Prevents Ketamine-Induced Stress Resilience in Females. eNeuro. vol 5. issue 1. 2019-01-09. PMID:29516036. |
ketamine given one week prior to an uncontrollable stressor (inescapable tailshock; is) reduced typical stress-induced activation of the serotonergic (5-ht) dorsal raphe nucleus (drn) and eliminated drn-dependent juvenile social exploration (jse) deficits 24 h after the stressor. |
2019-01-09 |
2023-08-13 |
rat |
| Luisa Prochazkova, Dominique P Lippelt, Lorenza S Colzato, Martin Kuchar, Zsuzsika Sjoerds, Bernhard Homme. Exploring the effect of microdosing psychedelics on creativity in an open-label natural setting. Psychopharmacology. vol 235. issue 12. 2019-01-09. PMID:30357434. |
taking microdoses (a mere fraction of normal doses) of psychedelic substances, such as truffles, recently gained popularity, as it allegedly has multiple beneficial effects including creativity and problem-solving performance, potentially through targeting serotonergic 5-ht |
2019-01-09 |
2023-08-13 |
Not clear |
| Anna Bravermanová, Michaela Viktorinová, Filip Tylš, Tomáš Novák, Renáta Androvičová, Jakub Korčák, Jiří Horáček, Marie Balíková, Inga Griškova-Bulanova, Dominika Danielová, Přemysl Vlček, Pavel Mohr, Martin Brunovský, Vlastimil Koudelka, Tomáš Páleníče. Psilocybin disrupts sensory and higher order cognitive processing but not pre-attentive cognitive processing-study on P300 and mismatch negativity in healthy volunteers. Psychopharmacology. vol 235. issue 2. 2018-12-31. PMID:29302713. |
similar findings were observed in a glutamatergic model of psychosis, but the role of serotonergic 5-ht |
2018-12-31 |
2023-08-13 |
human |
| Philippa M Warren, Stephanie C Steiger, Thomas E Dick, Peter M MacFarlane, Warren J Alilain, Jerry Silve. Rapid and robust restoration of breathing long after spinal cord injury. Nature communications. vol 9. issue 1. 2018-12-31. PMID:30482901. |
however, in a sub-population of animals, this combination treatment caused excess serotonergic (5ht) axon sprouting leading to aberrant tonic activity in the diaphragm that could be mitigated via 5ht2 receptor blockade. |
2018-12-31 |
2023-08-13 |
rat |
| Isadora Braga Contreiras Carneiro, Ana Elisa Toscano, Diego Cabral Lacerda, Marcela de Sá Barreto da Cunha, Raul Manhães de Castro, Tereza Cristina Bonfim de Jesus Deiró, Jairza Maria Barreto Medeiro. L-tryptophan administration and increase in cerebral serotonin levels: Systematic review. European journal of pharmacology. vol 836. 2018-12-27. PMID:30098308. |
the administration of trp is used in experimental studies to manipulate the serotonergic system, however the dose of trp required to raise brain 5-ht levels is controversial. |
2018-12-27 |
2023-08-13 |
Not clear |
| Hai-Quyen Tran, Youngho Lee, Eun-Joo Shin, Choon-Gon Jang, Ji Hoon Jeong, Akihiro Mouri, Kuniaki Saito, Toshitaka Nabeshima, Hyoung-Chun Ki. PKCδ Knockout Mice Are Protected from Dextromethorphan-Induced Serotonergic Behaviors in Mice: Involvements of Downregulation of 5-HT Molecular neurobiology. vol 55. issue 10. 2018-12-18. PMID:29468562. |
pkcδ knockout mice are protected from dextromethorphan-induced serotonergic behaviors in mice: involvements of downregulation of 5-ht we investigated whether a specific serotonin (5-ht) receptor-mediated mechanism was involved in dextromethorphan (dm)-induced serotonergic behaviors. |
2018-12-18 |
2023-08-13 |
mouse |
| Hiroyuki Muraoka, Hidehiro Oshibuchi, Masahiko Kawano, Takaaki Kawano, Takahiro Tsutsumi, Makiko Yamada, Jun Ishigooka, Katsuji Nishimura, Ken Inad. Escitalopram attenuates fear stress-induced increase in amygdalar dopamine following methamphetamine-induced sensitisation: Implications of fine-tuning action of selective serotonin reuptake inhibitors on emotional processing. European journal of pharmacology. vol 834. 2018-12-18. PMID:29981749. |
serotonin reuptake inhibitors modulate the serotonergic pathways of the nervous system and are widely used for treating psychiatric conditions such as anxiety and depression. |
2018-12-18 |
2023-08-13 |
rat |
| Xiaoyin Zhuang, Haiyun Xu, Zeman Fang, Chongtao Xu, Chaobiao Xue, Xiaohong Hon. Platelet serotonin and serotonin transporter as peripheral surrogates in depression and anxiety patients. European journal of pharmacology. vol 834. 2018-12-18. PMID:30031795. |
previous studies suggested that serotonergic neurons and platelets share similarities in serotonin (5-ht) uptake by serotonin transporter (sert), storage, metabolism and release mechanisms, indicating that platelets may be used as a reliable peripheral surrogate to measure central sert activity in neuropsychiatric research. |
2018-12-18 |
2023-08-13 |
human |
| Marie K Holt, Ida J Llewellyn-Smith, Frank Reimann, Fiona M Gribble, Stefan Trap. Serotonergic modulation of the activity of GLP-1 producing neurons in the nucleus of the solitary tract in mouse. Molecular metabolism. vol 6. issue 8. 2018-12-12. PMID:28752054. |
here, we investigate whether ppg neurons receive serotonergic input and respond to 5-ht. |
2018-12-12 |
2023-08-13 |
mouse |
| F Schwaller, A H Kanellopoulos, M Fitzgeral. The developmental emergence of differential brainstem serotonergic control of the sensory spinal cord. Scientific reports. vol 7. issue 1. 2018-12-11. PMID:28533557. |
here we present evidence that descending serotonergic fibres not only inhibit nociceptive activity, but also facilitate non-noxious tactile activity in the healthy adult rat spinal dorsal horn via activation of spinal 5-ht |
2018-12-11 |
2023-08-13 |
rat |
| Chayenne Karine Ferreira Gomes, Tamiris Vieira-Fonseca, Fernanda Brito Melo-Felippe, Juliana Braga de Salles Andrade, Leonardo F Fontenelle, Fabiana Barzotti Kohlrausc. Association analysis of SLC6A4 and HTR2A genes with obsessive-compulsive disorder: Influence of the STin2 polymorphism. Comprehensive psychiatry. vol 82. 2018-12-11. PMID:29331882. |
given the potent anti-obsessional effects of the so-called serotonin reuptake inhibitors, genes related to serotonergic system may be well implicated in the etiopathogenesis of ocd. |
2018-12-11 |
2023-08-13 |
Not clear |
| Shunchang Wang, Zhaoxia Chu, Kegui Zhang, Guopeng Mia. Cadmium-induced serotonergic neuron and reproduction damages conferred lethality in the nematode Caenorhabditis elegans. Chemosphere. vol 213. 2018-12-11. PMID:30205271. |
cadmium exposure resulted in shrinkage of serotonergic neuronal body and reduced expressions of tryptophan hydroxylase, the key enzyme for serotonin synthesis. |
2018-12-11 |
2023-08-13 |
caenorhabditis_elegans |
| Károly Elekes, László Hiripi, Gábor Balog, Gábor Maász, Izabella Battonyai, Marina Yu Khabarova, Réka Horváth, Elena E Voronezhskay. Serotonergic regulation of the buccal (feeding) rhythm of the pond snail, Lymnaea stagnalis. An immunocytochemical, biochemical and pharmacological approach. Acta biologica Hungarica. vol 69. issue 3. 2018-12-11. PMID:30257576. |
in order to have a detailed insight into this process, we investigated the serotonergic regulation of the buccal (feeding) rhythm in 100% stage embryos of the pond snail, lymnaea stagnalis, applying quantitative immunohistochemistry combined with the pharmacological manipulation of the serotonin (5-ht) synthesis, by either stimulating (by the 5-ht precursor 5-hydroxytryptophan, 5-htp) or inhibiting (by the 5-ht synthesis blocker para-chlorophenylalanine, pcpa) it. |
2018-12-11 |
2023-08-13 |
Not clear |
| K P C Kuypers, R de la Torre, M Farre, L Xicota, E B de Sousa Fernandes Perna, E L Theunissen, J G Ramaeker. Depressive mood ratings are reduced by MDMA in female polydrug ecstasy users homozygous for the l-allele of the serotonin transporter. Scientific reports. vol 8. issue 1. 2018-11-27. PMID:29348651. |
mdma exerts its main effects via the serotonergic system and the serotonin transporter. |
2018-11-27 |
2023-08-13 |
Not clear |
| Kimberly Little, Christine M Lin, Paul M Reynold. Delayed Serotonin Syndrome in the Setting of a Mixed Fluoxetine and Serotonin Antagonist Overdose. The American journal of case reports. vol 19. 2018-11-26. PMID:29795058. |
background serotonin syndrome is a condition characterized predominantly by neuromuscular symptoms and altered thermoregulation in response to serotonergic overtone. |
2018-11-26 |
2023-08-13 |
Not clear |
| Kimberly Little, Christine M Lin, Paul M Reynold. Delayed Serotonin Syndrome in the Setting of a Mixed Fluoxetine and Serotonin Antagonist Overdose. The American journal of case reports. vol 19. 2018-11-26. PMID:29795058. |
in the setting of serotonergic overdose, the onset of serotonin syndrome is usually within 4 to 13 h. here, we report a case of delayed-onset serotonin syndrome in a patient who ingested a mixture of longer-acting serotonin agonists with serotonin antagonists. |
2018-11-26 |
2023-08-13 |
Not clear |