| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Danilo De Gregorio, Justine P Enns, Nicolas A Nuñez, Luca Posa, Gabriella Gobb. d-Lysergic acid diethylamide, psilocybin, and other classic hallucinogens: Mechanism of action and potential therapeutic applications in mood disorders. Progress in brain research. vol 242. 2019-03-29. PMID:30471683. |
lsd and psilocybin have demonstrated mood-modulating properties likely due to their capacity to modulate serotonergic (5-ht), dopaminergic (da) and glutamatergic systems. |
2019-03-29 |
2023-08-13 |
Not clear |
| Xiaoqing Peng, Lisa A Brenner, Ashwin J Mathai, Thomas B Cook, Dietmar Fuchs, Nadine Postolache, Maureen W Groer, Janardan P Pandey, Farooq Mohyuddin, Ina Giegling, Abhishek Wadhawan, Annette M Hartmann, Bettina Konte, Lena Brundin, Marion Friedl, John W Stiller, Christopher A Lowry, Dan Rujescu, Teodor T Postolach. Moderation of the relationship between Toxoplasma gondii seropositivity and trait impulsivity in younger men by the phenylalanine-tyrosine ratio. Psychiatry research. vol 270. 2019-03-26. PMID:30057257. |
as dopaminergic and serotonergic signaling regulate impulsivity, and as t. gondii directly and indirectly affects dopaminergic signaling and induces activation of the kynurenine pathway leading to the diversion of tryptophan from serotonin production, we investigated if dopamine and serotonin precursors or the tryptophan metabolite kynurenine interact with the t. gondii-impulsivity association. |
2019-03-26 |
2023-08-13 |
human |
| H Palma-Gudiel, V Peralta, M Deuschle, V Navarro, L Fañaná. Epigenetics-by-sex interaction for somatization conferred by methylation at the promoter region of SLC6A4 gene. Progress in neuro-psychopharmacology & biological psychiatry. vol 89. 2019-03-25. PMID:30201454. |
the serotonin transporter (sert), encoded by slc6a4 gene, has received major attention due to its crucial role in serotonergic transmission. |
2019-03-25 |
2023-08-13 |
Not clear |
| Shami Kanekar, Chandni S Sheth, Hendrik J Ombach, Paul R Olson, Olena V Bogdanova, Matthew Petersen, Chloe E Renshaw, Young-Hoon Sung, Kristen E D'Anci, Perry F Rensha. Hypobaric hypoxia exposure in rats differentially alters antidepressant efficacy of the selective serotonin reuptake inhibitors fluoxetine, paroxetine, escitalopram and sertraline. Pharmacology, biochemistry, and behavior. vol 170. 2019-03-22. PMID:29738811. |
unlike the other ssris, sertraline can improve both serotonergic and dopaminergic transmission, and may be less impacted by a hypoxia-induced serotonin deficit. |
2019-03-22 |
2023-08-13 |
rat |
| Kee-Chan Ahn, Glen B Baker, Won-Cheoul Jang, Hyeon-Cheol Cha, Myung Jin Moon, Mee-Sook Son. Roles of 5-HT on phase transition of neurite outgrowth in the identified serotoninergic neuron C1, Helisoma trivolvis. Invertebrate neuroscience : IN. vol 18. issue 3. 2019-03-22. PMID:30128715. |
in this study, we investigated roles of 5-ht on neurite outgrowth using single serotonergic neurons c1 isolated from helisoma trivolvis. |
2019-03-22 |
2023-08-13 |
Not clear |
| B Sagalajev, H Wei, Z Chen, I Albayrak, A Koivisto, A Pertovaar. Oxidative Stress in the Amygdala Contributes to Neuropathic Pain. Neuroscience. vol 387. 2019-03-14. PMID:29274353. |
here we studied whether amygdaloid administration of antioxidants or antagonists of trpa1 that is among ion channels activated by oxidative stress attenuates nociceptive or affective pain in experimental neuropathy, and whether this effect involves amygdaloid astrocytes or descending serotonergic pathways acting on the spinal 5-ht |
2019-03-14 |
2023-08-13 |
Not clear |
| Jacob C Brewer, Andrew C Olson, Kevin M Collins, Michael R Koell. Serotonin and neuropeptides are both released by the HSN command neuron to initiate Caenorhabditis elegans egg laying. PLoS genetics. vol 15. issue 1. 2019-03-11. PMID:30677018. |
for example, serotonergic neurons in mammalian brain express the neuropeptide substance p, but it is unclear how this co-released neuropeptide might modulate serotonin signaling. |
2019-03-11 |
2023-08-13 |
caenorhabditis_elegans |
| Jacob C Brewer, Andrew C Olson, Kevin M Collins, Michael R Koell. Serotonin and neuropeptides are both released by the HSN command neuron to initiate Caenorhabditis elegans egg laying. PLoS genetics. vol 15. issue 1. 2019-03-11. PMID:30677018. |
the serotonergic hermaphrodite specific neurons (hsns) are command motor neurons within the egg-laying circuit which have been shown to release serotonin to initiate egg-laying behavior. |
2019-03-11 |
2023-08-13 |
caenorhabditis_elegans |
| Michael A Thornton, Manan D Mehta, Tyler T Morad, Kaitlin L Ingraham, Rana R Khankan, Khris G Griffis, Anthony K Yeung, Hui Zhong, Roland R Roy, V Reggie Edgerton, Patricia E Phelp. Evidence of axon connectivity across a spinal cord transection in rats treated with epidural stimulation and motor training combined with olfactory ensheathing cell transplantation. Experimental neurology. vol 309. 2019-03-04. PMID:30056160. |
analyses showed that the number of serotonergic (5-ht) axons that crossed the rostral scar border and the area of neurofilament-positive axons in the injury site were both greater in oec- than fb-treated rats. |
2019-03-04 |
2023-08-13 |
rat |
| Hai Zhang, Kuan Li, Hong-Sheng Chen, Shuang-Qi Gao, Zhi-Xuan Xia, Jie-Ting Zhang, Fang Wang, Jian-Guo Che. Dorsal raphe projection inhibits the excitatory inputs on lateral habenula and alleviates depressive behaviors in rats. Brain structure & function. vol 223. issue 5. 2019-02-27. PMID:29460052. |
hypofunction of the serotonergic (5-ht) system has close relationship with the symptoms in major depressive disorders (mdd), however, the underlying neural circuitry mechanisms are not fully understood. |
2019-02-27 |
2023-08-13 |
rat |
| Lianwei Mu, Dong Dong Xia, Teresa Michalkiewicz, Matthew Hodges, Gary Mouradian, Girija G Konduri, Margaret T T Wong-Rile. Effects of neonatal hyperoxia on the critical period of postnatal development of neurochemical expressions in brain stem respiratory-related nuclei in the rat. Physiological reports. vol 6. issue 5. 2019-02-21. PMID:29516654. |
in agreement with our previous findings, levels of cytochrome oxidase, brain-derived neurotrophic factor (bdnf), trkb (bdnf receptor), and several serotonergic proteins (5-ht |
2019-02-21 |
2023-08-13 |
rat |
| Kenichi Fukumoto, Michihiko Iijima, Takeo Funakoshi, Shigeyuki Chak. 5-HT Neuropharmacology. vol 137. 2019-02-20. PMID:29738849. |
5-ht we previously reported that serotonergic transmission is involved in the antidepressant effects of metabotropic glutamate 2/3 (mglu2/3) receptor antagonists. |
2019-02-20 |
2023-08-13 |
Not clear |
| Daniela Baptista-de-Souza, Vinícius Pelarin, Lucas Canto-de-Souza, Ricardo Luiz Nunes-de-Souza, Azair Canto-de-Souz. Interplay between 5-HT Neuropharmacology. vol 140. 2019-02-20. PMID:30056125. |
as a type of defensive reaction, the oaa has been investigated through systemic and intramesencephalic (e.g., dorsal portion of the periaqueductal gray - dpag) injections of anxiolytic-like drugs [e.g., serotonergic (5-ht) receptor agonists or antagonists]. |
2019-02-20 |
2023-08-13 |
Not clear |
| Grzegorz Satała, Beata Duszyńska, Tomasz Lenda, Gabriel Nowak, Andrzej J Bojarsk. Allosteric Inhibition of Serotonin 5-HT Molecular neurobiology. vol 55. issue 4. 2019-02-11. PMID:28455702. |
allosteric inhibition of serotonin 5-ht the allosteric regulation of g protein-coupled receptors (gpcrs) is a well-known phenomenon, but there are only a few examples of allosteric modulation within the metabotropic serotonergic receptor family. |
2019-02-11 |
2023-08-13 |
Not clear |
| Mihye Ko, Smi Choi-Kwon, Sang-Eun Jun, Ju Han Kim, Kyung-Hee Cho, Hyun-Wook Nah, Hasup Song, Jong S Ki. Poststroke emotional disturbances and a tryptophan hydroxylase 2 gene polymorphism. Brain and behavior. vol 8. issue 2. 2019-02-11. PMID:29484259. |
despite reports on serotonergic involvement in the etiology of poststroke emotional dysfunction (psed), the role of serotonin synthesizing tryptophan hydroxylase 2 (tph2) genes in the development of psed remains unclear. |
2019-02-11 |
2023-08-13 |
Not clear |
| Koen Willem Ottenhof, Mari Sild, Mélissa Luce Lévesque, Henricus Gerardus Ruhé, Linda Booi. TPH2 polymorphisms across the spectrum of psychiatric morbidity: A systematic review and meta-analysis. Neuroscience and biobehavioral reviews. vol 92. 2019-02-11. PMID:29775696. |
characterizing how exactly the different tph2 variants influence the serotonergic neurotransmission is a next necessary step in understanding the psychiatric disorders where serotonin is implicated. |
2019-02-11 |
2023-08-13 |
Not clear |
| Hannah Weinberg-Wolf, Nicholas A Fagan, George M Anderson, Marios Tringides, Olga Dal Monte, Steve W C Chan. The effects of 5-hydroxytryptophan on attention and central serotonin neurochemistry in the rhesus macaque. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 43. issue 7. 2019-02-08. PMID:29463909. |
thus, our results suggest that baseline central serotonergic functioning may underlie and predict variation in serotonin's effects on cognitive operation. |
2019-02-08 |
2023-08-13 |
monkey |
| Hannah Weinberg-Wolf, Nicholas A Fagan, George M Anderson, Marios Tringides, Olga Dal Monte, Steve W C Chan. The effects of 5-hydroxytryptophan on attention and central serotonin neurochemistry in the rhesus macaque. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 43. issue 7. 2019-02-08. PMID:29463909. |
our findings may help inform serotonin's role in psychopathology and help clinicians predict how serotonergic interventions will influence pathologies. |
2019-02-08 |
2023-08-13 |
monkey |
| Alexandrine Robert, Tiphaine Monsinjon, Romain Péden, Virginie Rasoamampianina, Jean-Claude Le Mével, Thomas Knigg. In vivo effects of serotonin and fluoxetine on cardio-ventilatory functions in the shore crab Carcinus maenas (L. 1758). Aquatic toxicology (Amsterdam, Netherlands). vol 207. 2019-02-08. PMID:30557758. |
selective serotonin reuptake inhibitors (ssris) modulate the serotonergic system and thus affect these functions. |
2019-02-08 |
2023-08-13 |
Not clear |
| Julien Volle, Tatiana Bregman, Brian Scott, Mustansir Diwan, Roger Raymond, Paul J Fletcher, José N Nobrega, Clement Haman. Deep brain stimulation and fluoxetine exert different long-term changes in the serotonergic system. Neuropharmacology. vol 135. 2019-02-04. PMID:29505786. |
both selective serotonin reuptake inhibitors (ssris) and ventromedial prefrontal cortex (vmpfc) deep brain stimulation (dbs) modulate serotonergic activity. |
2019-02-04 |
2023-08-13 |
rat |