| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jayne R Bramley, Patricia J Sollars, Gary E Pickard, F Edward Dude. 5-HT1B receptor-mediated presynaptic inhibition of GABA release in the suprachiasmatic nucleus. Journal of neurophysiology. vol 93. issue 6. 2005-07-15. PMID:15716370. |
the suprachiasmatic nucleus (scn) receives a dense serotonergic innervation that modulates photic input to the scn via serotonin 1b (5-ht1b) presynaptic receptors on retinal glutamatergic terminals. |
2005-07-15 |
2023-08-12 |
mouse |
| Irina Pavlovna Butkevich, Victor Anatol'evich Mikhailenko, Elena Andreevna Vershinina, Ludmila Ivanovna Khozhai, Igor'Pavlovich Grigorev, Vladimir Alexandrovich Otelli. Reduced serotonin synthesis during early embryogeny changes effect of subsequent prenatal stress on persistent pain in the formalin test in adult male and female rats. Brain research. vol 1042. issue 2. 2005-07-15. PMID:15854586. |
pregnant dams were injected with para-chlorophenylalanine (pcpa, 400 mg/kg/2 ml, ip), producing 5-ht depletion during the early period of fetal serotonergic system development. |
2005-07-15 |
2023-08-12 |
rat |
| Danial E Bake. Rationale for using serotonergic agents to treat irritable bowel syndrome. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists. vol 62. issue 7. 2005-07-14. PMID:15790796. |
the role of serotonin in gastrointestinal (gi)-tract functioning, the pharmacologic rationale for using serotonergic agents in the treatment of irritable bowel syndrome (ibs), and clinical experience with novel serotonergic agents are described. |
2005-07-14 |
2023-08-12 |
Not clear |
| Daniel P Seeburg, Xiaojin Liu, Chinfei Che. Frequency-dependent modulation of retinogeniculate transmission by serotonin. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 48. 2005-07-12. PMID:15574745. |
to understand how serotonergic inhibition of synaptic transmission influences the transfer of information at this synapse, we examined the epscs and firing responses of relay neurons to 5-carboxytryptamine (5-ct), a 5-ht1 receptor agonist that preferentially activates the presynaptic over postsynaptic modulatory effects of serotonin. |
2005-07-12 |
2023-08-12 |
mouse |
| C Mizrahi, A Stojanovic, M Urbina, I Carreira, L Lim. Differential cAMP levels and serotonin effects in blood peripheral mononuclear cells and lymphocytes from major depression patients. International immunopharmacology. vol 4. issue 8. 2005-07-11. PMID:15270025. |
the present report indicates: (1) differential responses of immune cells from control individuals and depressed patients, with lower apparent adenylate cyclase activity in patient's cells; (2) variation in the population of cells, with responses to serotonergic agonists being lower in mononuclear cells and higher in lymphocytes from major depression patients; (3) increases of camp levels by serotonin and 5ht1a agonist in the patient's cells; and (4) evidence of impairment in serotonergic transduction systems in immune cells during depression. |
2005-07-11 |
2023-08-12 |
human |
| M Chennaoui, C Drogou, D Gomez-Merino, C Y Guezenne. Effects of an intense training on functional activity of 5-HT(1B) receptors in human peripheral blood lymphocytes. Neuroscience letters. vol 382. issue 1-2. 2005-07-11. PMID:15885906. |
at the periphery, the serotonergic system appears to possess a regulatory activity via 5-ht 1b receptors. |
2005-07-11 |
2023-08-12 |
human |
| Masahiro Hayashi, Tsutomu Bandoh, Daiki Ushizawa, Shinya Takada, Katsuji Hosh. Effects of acute and short-term administration of tryptophan plus ethanol on noradrenaline and serotonin metabolites in the locus coeruleus. Alcohol (Fayetteville, N.Y.). vol 34. issue 2-3. 2005-07-11. PMID:15902917. |
results of the current study seem to indicate that the stimulation of 5-ht metabolism in locus coeruleus serotonergic neurons by tryptophan was strengthened by the simultaneous administration of ethanol in short-term experiments, and that the increased 5-hiaa concentrations in the locus coeruleus are responsible for behavioral activation. |
2005-07-11 |
2023-08-12 |
rat |
| David Jorda. Vagal control of the heart: central serotonergic (5-HT) mechanisms. Experimental physiology. vol 90. issue 2. 2005-07-05. PMID:15604109. |
vagal control of the heart: central serotonergic (5-ht) mechanisms. |
2005-07-05 |
2023-08-12 |
Not clear |
| S Wee, K G Anderson, M H Baumann, R B Rothman, B E Blough, W L Woolverto. Relationship between the serotonergic activity and reinforcing effects of a series of amphetamine analogs. The Journal of pharmacology and experimental therapeutics. vol 313. issue 2. 2005-07-05. PMID:15677348. |
the present experiment was designed to examine this relationship for amphetamine analogs that varied in serotonin releasing potency and to evaluate whether serotonergic actions can affect reinforcing efficacy. |
2005-07-05 |
2023-08-12 |
monkey |
| Moonkyu Kang, Kwang-Ho Pyun, Choon-Gon Jang, Hyuntaek Kim, Hyunsu Bae, Insop Shi. Nelumbinis Semen reverses a decrease in hippocampal 5-HT release induced by chronic mild stress in rats. The Journal of pharmacy and pharmacology. vol 57. issue 5. 2005-06-28. PMID:15901354. |
these results suggest that ns increases the serotonin levels normally decreased in depression, resulting in an enhancement of central serotonergic transmission and possible therapeutic action in depression. |
2005-06-28 |
2023-08-12 |
rat |
| O T Ginawi, A A Al-Majed, A K Al-Suwaile. Ondansetron, a selective 5-HT3 antagonist, antagonizes methamphetamine-induced anorexia in mice. Pharmacological research. vol 51. issue 3. 2005-06-24. PMID:15661576. |
effects of some selective serotonergic (5-ht) antagonists on methamphetamine-induced anorexia were investigated in male mice. |
2005-06-24 |
2023-08-12 |
mouse |
| Cátia Isumi Miyase, Renato Kishi, Renato Leonardo de Freitas, Denise Amorim Paz, Norberto Cysne Coimbr. Involvement of pre- and post-synaptic serotonergic receptors of dorsal raphe nucleus neural network in the control of the sweet-substance-induced analgesia in adult Rattus norvegicus (Rodentia, Muridae). Neuroscience letters. vol 379. issue 3. 2005-06-24. PMID:15843057. |
considering that the blockade of pre-synaptic serotonergic receptors of the neural networks of the dorsal raphe nucleus with methiothepin did not decrease the sweet-substance-induced antinociception, and the central blockade of post-synaptic serotonergic receptors decreased the sucrose-induced analgesia, the modulation of the release of serotonin in the neural substrate of the dorsal raphe nucleus seems to be crucial for the organization of this interesting antinociceptive process. |
2005-06-24 |
2023-08-12 |
rat |
| Janusz K Rybakowski, Aleksandra Suwalska, Piotr M Czerski, Monika Dmitrzak-Weglarz, Anna Leszczynska-Rodziewicz, Joanna Hause. Prophylactic effect of lithium in bipolar affective illness may be related to serotonin transporter genotype. Pharmacological reports : PR. vol 57. issue 1. 2005-06-21. PMID:15849387. |
serotonin transporter promoter length polymorphism (5-httlpr) has been implicated in the pathogenesis of mood disorders and in the therapeutic response to serotonergic drugs. |
2005-06-21 |
2023-08-12 |
Not clear |
| David S Janowsky, Mahesh Shetty, Jarrett Barnhill, Belal Elamir, John M Davi. Serotonergic antidepressant effects on aggressive, self-injurious and destructive/disruptive behaviours in intellectually disabled adults: a retrospective, open-label, naturalistic trial. The international journal of neuropsychopharmacology. vol 8. issue 1. 2005-06-13. PMID:15482629. |
the current study consisted of a review of the treatment response to a variety of serotonergic antidepressants, consisting of selective serotonin reuptake inhibitors (ssris ) (n = 36) and clomipramine (n = 2) in 38 institutionalized intellectually disabled adults (20 males, 18 females; mean age 45.6 yr, age range 18-74 yr). |
2005-06-13 |
2023-08-12 |
human |
| Peter Gaszner, Ildikó Mikly. The use of the synthetic enhancer substances (-)-deprenyl and (-)-BPAP in major depression. Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology. vol 6. issue 4. 2005-06-13. PMID:15825677. |
the finding that phenylethylamine and tryptamine are endogenous enhancers of the impulse propagation mediated release of catecholamines and serotonin in the brain, and the development of synthetic mesencephalic enhancer substances opened the possibility to stimulate catecholaminergic and serotonergic neurons in the mesencephalon via a previously unknown mechanism. |
2005-06-13 |
2023-08-12 |
Not clear |
| Vincent Contesse, Yves Reznik, Estelle Louiset, Céline Duparc, Dorthe Cartier, Flavie Sicard, Annie Laquerriere, Francoise Parmentier, Jean-Marc Kuhn, Hubert Vaudry, Hervé Lefebvr. Abnormal sensitivity of cortisol-producing adrenocortical adenomas to serotonin: in vivo and in vitro studies. The Journal of clinical endocrinology and metabolism. vol 90. issue 5. 2005-06-09. PMID:15705918. |
the corticotropic effect of 5-ht was inhibited by the specific 5-ht4 receptor antagonist gr 113808 and more potently by methiothepin, a nonspecific serotonergic antagonist having no affinity for the 5-ht4 receptor. |
2005-06-09 |
2023-08-12 |
human |
| Vincent Contesse, Yves Reznik, Estelle Louiset, Céline Duparc, Dorthe Cartier, Flavie Sicard, Annie Laquerriere, Francoise Parmentier, Jean-Marc Kuhn, Hubert Vaudry, Hervé Lefebvr. Abnormal sensitivity of cortisol-producing adrenocortical adenomas to serotonin: in vivo and in vitro studies. The Journal of clinical endocrinology and metabolism. vol 90. issue 5. 2005-06-09. PMID:15705918. |
these results show that the hypersensitivity of the tumors to 5-ht was related to tissue expression of an ectopic serotonergic receptor in addition to the eutopic 5-ht4 receptor. |
2005-06-09 |
2023-08-12 |
human |
| Daniella Amital, Leah Fostick, Yehuda Sasson, Seth Kindler, Howard Amital, Joseph Zoha. Anxiogenic effects of Sumatriptan in panic disorder: a double-blind, placebo-controlled study. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 15. issue 3. 2005-06-08. PMID:15820416. |
our goal was to further examine central serotonergic function in panic patients using autonomic and subjective responses to the postsynaptic serotonin 5-ht1d receptor agonist sumatriptan. |
2005-06-08 |
2023-08-12 |
Not clear |
| Laura Dazzi, Emanuele Seu, Giulia Cherchi, Giovanni Biggi. Chronic administration of the SSRI fluvoxamine markedly and selectively reduces the sensitivity of cortical serotonergic neurons to footshock stress. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 15. issue 3. 2005-06-08. PMID:15820417. |
given the different role played by serotonin and norepinephrine in the modulation of the stress response, the availability of drugs able to selectively modulate the plastic response of serotonergic neurons to stress in specific brain areas might be important for the pharmacotherapy of anxiety disorders. |
2005-06-08 |
2023-08-12 |
rat |
| Romina Soledad Almirón, Oscar Angel Ramíre. Participation of dorsal raphe nucleus in the behavioral alteration observed after discontinuation of chronic diazepam administration: possible neural circuitry involved. Synapse (New York, N.Y.). vol 56. issue 2. 2005-06-06. PMID:15714479. |
in the present study, we investigated the involvement of the serotonergic (5-ht) system in the possible neural circuitry recruited during dz withdrawal and in the increased hippocampal synaptic plasticity associated with the discontinuation of chronic dz administration. |
2005-06-06 |
2023-08-12 |
Not clear |