| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Arboreliu. 5-HT1A receptor antagonists as putative adjuvants to antidepressants: preclinical and clinical evidence. IDrugs : the investigational drugs journal. vol 2. issue 2. 2005-10-13. PMID:16160947. |
in this review data are presented showing that adding a 5-ht1a receptor antagonist prevents this feedback inhibition of serotonergic cell firing and allows more 5-ht to be released. |
2005-10-13 |
2023-08-12 |
Not clear |
| J Sloan Mannin. Newer antidepressants in the primary care setting. Primary care companion to the Journal of clinical psychiatry. vol 6. issue Suppl 1. 2005-10-11. PMID:16001090. |
this article will summarize key features of 3 newer antidepressants that represent advances in psychopharmacology: mirtazapine, which has a dual effect on serotonergic and noradrenergic systems; escitalopram, the latest selective serotonin reuptake inhibitor, which is the first pure antidepressant stereoisomer in clinical use; and duloxetine, a dual reuptake inhibitor of norepinephrine and serotonin that is expected to be clinically available in the near future. |
2005-10-11 |
2023-08-12 |
Not clear |
| K Fukud. Novel hypothesis for the cause of panic disorder via the neuroepithelial bodies in the lung. Medical hypotheses. vol 64. issue 6. 2005-09-30. PMID:15823715. |
when 5-ht released from these cells along with bk cross the bbb, the release of 5-ht at the axonal terminals in the serotonergic neurons in the brain will be inhibited, since the 5-ht1 autoreceptor have a higher affinity for 5-ht than do the 5-ht2 receptors. |
2005-09-30 |
2023-08-12 |
Not clear |
| Piet Vanhaesebrouck, Freia De Bock, Alexandra Zecic, Claudine De Praeter, Koenraad Smets, Kris De Coen, Linde Goossen. Phototherapy-mediated syndrome of inappropriate secretion of antidiuretic hormone in an in utero selective serotonin reuptake inhibitor-exposed newborn infant. Pediatrics. vol 115. issue 5. 2005-09-27. PMID:15805337. |
although selective serotonin reuptake inhibitors (ssris) have gained wide acceptance in the off-label treatment of mental disorders in pregnant women, there seems to be an increased risk for serotonergic adverse effects in newborn infants who are exposed to ssris during late pregnancy. |
2005-09-27 |
2023-08-12 |
Not clear |
| Matthias Paul, Robert Callahan, John Au, Christoph H Kindler, C Spencer Yos. Antiemetics of the 5-hydroxytryptamine 3A antagonist class inhibit muscle nicotinic acetylcholine receptors. Anesthesia and analgesia. vol 101. issue 3. 2005-09-27. PMID:16115980. |
antagonists of the serotonergic 5-hydroxytryptamine 3a receptor (5-ht(3a)r) and muscle nicotinic acetylcholine receptors (nachr) are widely used in anesthesia practice. |
2005-09-27 |
2023-08-12 |
xenopus_laevis |
| Wolfgang Blenau, Arnd Bauman. Molecular characterization of the ebony gene from the American cockroach, Periplaneta americana. Archives of insect biochemistry and physiology. vol 59. issue 3. 2005-09-19. PMID:15986380. |
since the salivary glands in periplaneta are innervated by dopaminergic and serotonergic neurons, peaebony probably also biochemically modifies dopamine and serotonin in these acinar glands. |
2005-09-19 |
2023-08-12 |
drosophila_melanogaster |
| M Babette Fontenot, E Eugene Padgett, Amy M Dupuy, Cheryl R Lynch, Paolo B De Petrillo, J Dee Higle. The effects of fluoxetine and buspirone on self-injurious and stereotypic behavior in adult male rhesus macaques. Comparative medicine. vol 55. issue 1. 2005-09-16. PMID:15766212. |
the effects of two serotonergic agents--fluoxetine, a serotonin (5-ht) reuptake inhibitor, and buspirone, a 5-ht 1a agonist--on rates of self-injurious and stereotypic behavior were examined in 15 adult male macaca mulatta. |
2005-09-16 |
2023-08-12 |
monkey |
| R V Gaikwad, R K Gaonkar, S A Jadhav, V M Thorat, J H Jadhav, J J Balsar. Involvement of central serotonergic systems in dextromethorphan-induced behavioural syndrome in rats. Indian journal of experimental biology. vol 43. issue 7. 2005-09-15. PMID:16053268. |
this indicates that dextromethorphan induces the behavioural syndrome by releasing 5-ht from serotonergic neurons with resultant activation of the postsynaptic 5-ht1a receptors by the released 5-ht. |
2005-09-15 |
2023-08-12 |
rat |
| Junia Maria Netto Victoria, Jeane de Fátima Correia-Silva, Flávio Juliano Pimenta, Evanguedes Kalapothakis, Ricardo Santiago Gome. Serotonin transporter gene polymorphism (5-HTTLPR) in patients with recurrent aphthous stomatitis. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology. vol 34. issue 8. 2005-09-12. PMID:16091117. |
considerable evidence indicates that serotonergic mechanisms, particularly the serotonin transporter (5-htt) may be involved in psychological alterations. |
2005-09-12 |
2023-08-12 |
human |
| Luc Bergeron, Martin Boulé, Sébastien Perreaul. Serotonin toxicity associated with concomitant use of linezolid. The Annals of pharmacotherapy. vol 39. issue 5. 2005-09-08. PMID:15827071. |
to report 2 cases of serotonin toxicity (st) associated with concomitant use of linezolid and serotonergic drugs and review previously published case reports. |
2005-09-08 |
2023-08-12 |
Not clear |
| Pascal Bonaventure, Diane Nepomuceno, Kirsten Miller, Jingcai Chen, Chester Kuei, Fredrik Kamme, Da-Thao Tran, Timothy W Lovenberg, Changlu Li. Molecular and pharmacological characterization of serotonin 5-HT2A and 5-HT2B receptor subtypes in dog. European journal of pharmacology. vol 513. issue 3. 2005-09-01. PMID:15862800. |
both the canine 5-ht2a and 5-ht2b receptors have high affinity for [3h]5-ht (kd=4.50+/-0.89 nm and 3.10+/-0.82 nm, respectively) and, in general, the pharmacology of these two receptors matches closely the pharmacology of their human homologs for the 19 serotonergic ligands tested. |
2005-09-01 |
2023-08-12 |
human |
| Francisco F De-Miguel, Citlali Truet. Synaptic and extrasynaptic secretion of serotonin. Cellular and molecular neurobiology. vol 25. issue 2. 2005-09-01. PMID:16047543. |
serotonin is a major modulator of behavior in vertebrates and invertebrates and deficiencies in the serotonergic system account for several behavioral disorders in humans. |
2005-09-01 |
2023-08-12 |
Not clear |
| Irina Sokolchik, Takahiro Tanabe, Pierre F Baldi, Ji Ying Sz. Polymodal sensory function of the Caenorhabditis elegans OCR-2 channel arises from distinct intrinsic determinants within the protein and is selectively conserved in mammalian TRPV proteins. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 4. 2005-08-31. PMID:15673683. |
furthermore, expression of either the mouse or human trpv2 gene under the ocr-2 promoter can substantially restore 5-ht biosynthesis in ocr-2-null mutants but cannot improve the deficits in osmotic or olfactory sensation, suggesting that trpv2 can substitute for the role of ocr-2 only in serotonergic neurons. |
2005-08-31 |
2023-08-12 |
mouse |
| Catherine M Dempsey, Scott M Mackenzie, Andrew Gargus, Gabriela Blanco, Ji Ying Sz. Serotonin (5HT), fluoxetine, imipramine and dopamine target distinct 5HT receptor signaling to modulate Caenorhabditis elegans egg-laying behavior. Genetics. vol 169. issue 3. 2005-08-29. PMID:15654117. |
using the well-established serotonergic response in c. elegans egg-laying behavior as a paradigm, we show that action of fluoxetine and imipramine at the 5ht reuptake transporter (sert) and at 5ht receptors are separable mechanisms. |
2005-08-29 |
2023-08-12 |
caenorhabditis_elegans |
| Enrique Baca-García, Beatríz Rodríguez Salgado, Helen Dolengevich Segal, Concepción Vaquero Lorenzo, Mercedes Navio Acosta, Manuel Arrojo Romero, Montserrat Díaz Hernández, Jeronimo Saiz-Ruiz, Jose Fernandez Piqueras, Jose de Leo. A pilot genetic study of the continuum between compulsivity and impulsivity in females: the serotonin transporter promoter polymorphism. Progress in neuro-psychopharmacology & biological psychiatry. vol 29. issue 5. 2005-08-26. PMID:15908092. |
the serotonin transporter (5-htt) gene is one of the main genes that control serotonergic function. |
2005-08-26 |
2023-08-12 |
human |
| J Gallinat, D Kunz, U E Lang, P Kalus, G Juckel, J Eggers, R Mahlberg, M Staedtgen, C Wernicke, H Rommelspacher, M N Smolk. Serotonergic effects of smoking are independent from the human serotonin transporter gene promoter polymorphism: evidence from auditory cortical stimulus processing. Pharmacopsychiatry. vol 38. issue 4. 2005-08-26. PMID:16025417. |
serotonergic effects of smoking are independent from the human serotonin transporter gene promoter polymorphism: evidence from auditory cortical stimulus processing. |
2005-08-26 |
2023-08-12 |
human |
| Miles Gregory Cunningham, Caroline Martine Connor, Kehong Zhang, Francine Mary Bene. Diminished serotonergic innervation of adult medial prefrontal cortex after 6-OHDA lesions in the newborn rat. Brain research. Developmental brain research. vol 157. issue 2. 2005-08-24. PMID:15885807. |
the development of the serotonergic (5ht) and dopaminergic (da) systems may contribute to the onset of psychotic disorders during late adolescence and early adulthood. |
2005-08-24 |
2023-08-12 |
rat |
| Miles Gregory Cunningham, Caroline Martine Connor, Kehong Zhang, Francine Mary Bene. Diminished serotonergic innervation of adult medial prefrontal cortex after 6-OHDA lesions in the newborn rat. Brain research. Developmental brain research. vol 157. issue 2. 2005-08-24. PMID:15885807. |
we propose that the decrease in serotonergic fibers in mpfc in response to a neonatal depletion of dopamine may be due to the loss of a trophic effect of this system on 5ht neurons and/or fibers during development. |
2005-08-24 |
2023-08-12 |
rat |
| S Rossi, S Singer, E Shearman, H Sershen, A Lajth. The effects of cholinergic and dopaminergic antagonists on nicotine-induced cerebral neurotransmitter changes. Neurochemical research. vol 30. issue 4. 2005-08-24. PMID:16076024. |
in the hippocampal and cortical areas, the mechanisms of nicotine-induced dopamine increase seem to be similar, but the mechanisms seem to be different for noradrenergic and serotonergic systems, as shown by the fact that nicotine induces no change in norepinephrine and a decrease in serotonin in the hippocampus, while it induces an increase in both in the cortex. |
2005-08-24 |
2023-08-12 |
rat |
| Stephen B Manuck, Maria E Bleil, Karen L Petersen, Janine D Flory, J John Mann, Robert E Ferrell, Matthew F Muldoo. The socio-economic status of communities predicts variation in brain serotonergic responsivity. Psychological medicine. vol 35. issue 4. 2005-08-23. PMID:15856722. |
we reported previously that the socio-economic status (ses) of individuals predicts variation in brain serotonergic responsivity, as assessed by neuropharmacological challenge in an adult community sample, and that this association is qualified by allelic variation in the serotonin transporter gene-linked polymorphic region (5-httlpr). |
2005-08-23 |
2023-08-12 |
Not clear |