| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alejandro O Sodero, Analía Valdomero, Gabriel R Cuadra, Oscar A Ramírez, Otto A Orsinghe. Locus coeruleus activity in perinatally protein-deprived rats: effects of fluoxetine administration. European journal of pharmacology. vol 503. issue 1-3. 2005-04-25. PMID:15496293. |
since locus coeruleus dysfunction has been involved in different types of anxiety disorders and considering the modulating action of serotonergic transmission on locus coeruleus activity, we assessed the effect of fluoxetine, a selective serotonin reuptake inhibitor (ssri), on locus coeruleus activity as measured by the firing rate and the number of spontaneously active cells/track. |
2005-04-25 |
2023-08-12 |
rat |
| Motoko Honda, Keiko Imaida, Mitsuo Tanabe, Hideki On. Endogenously released 5-hydroxytryptamine depresses the spinal monosynaptic reflex via 5-HT1D receptors. European journal of pharmacology. vol 503. issue 1-3. 2005-04-25. PMID:15496296. |
in this study, we determined the effects of endogenous 5-ht, which was released from serotonergic terminals by dl-p-chloroamphetamine, on spinal reflexes. |
2005-04-25 |
2023-08-12 |
rat |
| Motoko Honda, Keiko Imaida, Mitsuo Tanabe, Hideki On. Endogenously released 5-hydroxytryptamine depresses the spinal monosynaptic reflex via 5-HT1D receptors. European journal of pharmacology. vol 503. issue 1-3. 2005-04-25. PMID:15496296. |
these results suggest that 5-ht released from serotonergic terminals depresses monosynaptic reflex transmission via 5-ht1d receptors. |
2005-04-25 |
2023-08-12 |
rat |
| Brian H Harvey, Carla Naciti, Linda Brand, Dan J Stei. Serotonin and stress: protective or malevolent actions in the biobehavioral response to repeated trauma? Annals of the New York Academy of Sciences. vol 1032. 2005-04-19. PMID:15677425. |
the serotonergic agent fluoxetine (flx; 10 mg/kg/d ip) administered 1 week before stress and continuing throughout the stress procedure, but not the 5ht depleter p-chloro-phenylalanine (pcpa; 300/100/50 mg/kg/d ip), prevented stress-induced cognitive dysfunction. |
2005-04-19 |
2023-08-12 |
rat |
| Florence Clénet, Martine Hascoët, Gilles Fillion, Hervé Galons, Michel Bouri. Role of GABA-ergic and serotonergic systems in the anxiolytic-like mechanism of action of a 5-HT-moduline antagonist in the mouse elevated plus maze. Behavioural brain research. vol 158. issue 2. 2005-04-19. PMID:15698901. |
hg1 mechanism of action in the mouse elevated plus maze seems to associate a gaba-ergic component exerting a limited regulation of 5-ht neuronal activity and a major serotonergic component, which seems to implicate presynaptic 5-ht1a and 5-ht1b receptors. |
2005-04-19 |
2023-08-12 |
mouse |
| Mattias Damberg, Lars Westberg, Cecilia Berggård, Mikael Landen, Charlotta Sundblad, Olle Eriksson, Tord Naessén, Agneta Ekman, Elias Eriksso. Investigation of transcription factor AP-2 beta genotype in women with premenstrual dysphoric disorder. Neuroscience letters. vol 377. issue 1. 2005-04-15. PMID:15722186. |
we have earlier shown that ap-2beta genotype is associated with serotonergic phenotypes and that brainstem levels of ap-2beta correlate positively to serotonin metabolism in rat frontal cortex. |
2005-04-15 |
2023-08-12 |
human |
| Benjamin N Greenwood, Teresa E Foley, Dan Burhans, Steven F Maier, Monika Fleshne. The consequences of uncontrollable stress are sensitive to duration of prior wheel running. Brain research. vol 1033. issue 2. 2005-04-13. PMID:15694921. |
the behavioral consequences of uncontrollable stress, or learned helplessness (lh) behaviors, are thought to involve hyperactivity of serotonergic (5-ht) neurons in the dorsal raphe nucleus (drn). |
2005-04-13 |
2023-08-12 |
rat |
| Yogesh Dwivedi, Amal C Mondal, Gurubasanagouda V Payappagoudar, Hooriyah S Rizav. Differential regulation of serotonin (5HT)2A receptor mRNA and protein levels after single and repeated stress in rat brain: role in learned helplessness behavior. Neuropharmacology. vol 48. issue 2. 2005-04-13. PMID:15695159. |
to examine the role of serotonergic (5ht) mechanisms in such behavior, we studied the expression of 5ht2a receptors in different brain areas of rats, and further investigated whether the alterations in expression of 5ht2a receptors are similar after single versus repeated stress. |
2005-04-13 |
2023-08-12 |
rat |
| Koen Schruers, Eric Grie. The effects of tianeptine or paroxetine on 35% CO2 provoked panic in panic disorder. Journal of psychopharmacology (Oxford, England). vol 18. issue 4. 2005-04-12. PMID:15582922. |
evidence suggests that increased 5-ht availability is important for the anti-panic effect of serotonergic drugs and in maintaining the response to selective serotonin reuptake inhibitors (ssris). |
2005-04-12 |
2023-08-12 |
Not clear |
| Tiffany A Mathews, Denise E Fedele, Francesca M Coppelli, Amy M Avila, Dennis L Murphy, Anne M Andrew. Gene dose-dependent alterations in extraneuronal serotonin but not dopamine in mice with reduced serotonin transporter expression. Journal of neuroscience methods. vol 140. issue 1-2. 2005-04-12. PMID:15589347. |
furthermore, use of zero net flux microdialysis appears warranted in investigations of serotonergic synaptic function where modest changes in extracellular 5-ht are thought to occur in response to altered uptake. |
2005-04-12 |
2023-08-12 |
mouse |
| Yinglun Sheng, Ling Wang, X Shawn Liu, Véronique Montplaisir, Mario Tiberi, Jay M Baltz, X Johné Li. A serotonin receptor antagonist induces oocyte maturation in both frogs and mice: evidence that the same G protein-coupled receptor is responsible for maintaining meiosis arrest in both species. Journal of cellular physiology. vol 202. issue 3. 2005-04-07. PMID:15499574. |
the unique ability of rit, among serotonergic antagonists, to induce gvbd did not match the antagonist profile of any known serotonin receptors including xenopus 5-ht7r, the only known g(s)-coupled serotonin receptor cloned so far in this species. |
2005-04-07 |
2023-08-12 |
mouse |
| Keiichi Ikeda, Katsuyoshi Tojo, Chikara Otsubo, Takashi Udagawa, Kensuke Kumazawa, Masahiro Ishikawa, Goro Tokudome, Tatsuo Hosoya, Naoko Tajima, William C Claycomb, Kazuwa Nakao, Masahiro Kawamur. 5-hydroxytryptamine synthesis in HL-1 cells and neonatal rat cardiocytes. Biochemical and biophysical research communications. vol 328. issue 2. 2005-04-07. PMID:15694378. |
some reports showed that serotonergic system might have existed and that 5-hydroxytryptamine (5-ht) was detected in the hamster heart. |
2005-04-07 |
2023-08-12 |
rat |
| Keiichi Ikeda, Katsuyoshi Tojo, Chikara Otsubo, Takashi Udagawa, Kensuke Kumazawa, Masahiro Ishikawa, Goro Tokudome, Tatsuo Hosoya, Naoko Tajima, William C Claycomb, Kazuwa Nakao, Masahiro Kawamur. 5-hydroxytryptamine synthesis in HL-1 cells and neonatal rat cardiocytes. Biochemical and biophysical research communications. vol 328. issue 2. 2005-04-07. PMID:15694378. |
so the present study was designed to define serotonergic system and to clarify which cell could produce 5-ht in the heart. |
2005-04-07 |
2023-08-12 |
rat |
| E Sylvester Vizi, Gabriella Zsilla, Marc G Caron, János P Kis. Uptake and release of norepinephrine by serotonergic terminals in norepinephrine transporter knock-out mice: implications for the action of selective serotonin reuptake inhibitors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 36. 2005-04-05. PMID:15356201. |
uptake and release of norepinephrine by serotonergic terminals in norepinephrine transporter knock-out mice: implications for the action of selective serotonin reuptake inhibitors. |
2005-04-05 |
2023-08-12 |
mouse |
| E Sylvester Vizi, Gabriella Zsilla, Marc G Caron, János P Kis. Uptake and release of norepinephrine by serotonergic terminals in norepinephrine transporter knock-out mice: implications for the action of selective serotonin reuptake inhibitors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 36. 2005-04-05. PMID:15356201. |
because the diffusion of ne may be spatially limited by serotonin transporters, the ssris, despite their selectivity, might enhance not only serotonergic but also noradrenergic neurotransmission, which might contribute to their antidepressant action. |
2005-04-05 |
2023-08-12 |
mouse |
| Sophie Mouillet-Richard, Mathéa Pietri, Benoît Schneider, Catherine Vidal, Vincent Mutel, Jean-Marie Launay, Odile Kellerman. Modulation of serotonergic receptor signaling and cross-talk by prion protein. The Journal of biological chemistry. vol 280. issue 6. 2005-04-05. PMID:15590675. |
here, we establish that antibody-mediated ligation of prpc concomitant to agonist stimulation of 5-ht receptors modulates the couplings of all three serotonergic receptors present on 1c115-ht cells. |
2005-04-05 |
2023-08-12 |
Not clear |
| Janine D Flory, Stephen B Manuck, Karen A Matthews, Matthew F Muldoo. Serotonergic function in the central nervous system is associated with daily ratings of positive mood. Psychiatry research. vol 129. issue 1. 2005-03-31. PMID:15572180. |
a neuropharmacological challenge was administered to index central serotonergic function, i.e., the maximal prolactin (prl) response to fenfluramine, a serotonin releasing agent. |
2005-03-31 |
2023-08-12 |
human |
| Jan Croonenberghs, Robert Verkerk, Simon Scharpe, Dirk Deboutte, Michael Mae. Serotonergic disturbances in autistic disorder: L-5-hydroxytryptophan administration to autistic youngsters increases the blood concentrations of serotonin in patients but not in controls. Life sciences. vol 76. issue 19. 2005-03-28. PMID:15733932. |
serotonergic disturbances in autistic disorder: l-5-hydroxytryptophan administration to autistic youngsters increases the blood concentrations of serotonin in patients but not in controls. |
2005-03-28 |
2023-08-12 |
human |
| Jan Croonenberghs, Robert Verkerk, Simon Scharpe, Dirk Deboutte, Michael Mae. Serotonergic disturbances in autistic disorder: L-5-hydroxytryptophan administration to autistic youngsters increases the blood concentrations of serotonin in patients but not in controls. Life sciences. vol 76. issue 19. 2005-03-28. PMID:15733932. |
differences in the peripheral metabolism of 5-ht which may not be observed in baseline conditions but which became clear after loading with 5-htp, suggest that an increased synthesis of 5-ht from its precursor 5-htp might be a one factor responsible for differences in the serotonergic system between autistic post-pubertal youngsters and normal controls. |
2005-03-28 |
2023-08-12 |
human |
| b' B Gruwez, C Gury, M-F Poirier, O Bouvet, A G\\xc3\\xa9rard, M-C Bourdel, F-J Bayl\\xc3\\xa9, J-P Oli\\xc3\\xa. [Comparison of two assessment tools of antidepressant side-effects: UKU scale versus spontaneous notification]. L\'Encephale. vol 30. issue 5. 2005-03-22. PMID:15627047.' |
overall, the efficacy of the newer antidepressants: serotonin selective reuptake inhibitors (ssri), selective serotonin/norepinephrine reuptake inhibitor (snri), noradrenergic and specific serotonergic antidepressant (nassa) and tianeptine is similar to that of the tricyclics, and so their acceptability/safety becomes a selection criterion for the clinician. |
2005-03-22 |
2023-08-12 |
Not clear |