| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yina Sun, Seetha Chebolu, Denise Henry, Sandeep Lankireddy, Nissar A Darman. An ontogenic study of receptor mechanisms by which acute administration of low-doses of methamphetamine suppresses DOI-induced 5-HT BMC neuroscience. vol 23. issue 1. 2022-01-05. PMID:34983399. |
doi ((±)-2, 5-dimethoxy-4-iodoamphetamine) is a direct-acting serotonergic 5-ht |
2022-01-05 |
2023-08-13 |
Not clear |
| Darwin Da Costa Guevara, Ernesto Trej. 5-HT Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi. vol 57. issue 0. 2022-01-04. PMID:34980821. |
this study supports the proposal that 5-ht directly contracts asm and characterizes pharmacologically the subtypes of serotonergic receptors involved. |
2022-01-04 |
2023-08-13 |
cattle |
| Saurabh Bhatia, Ahmed Al-Harrasi, Arun Kumar, Tapan Behl, Aayush Sehgal, Sukhbir Singh, Neelam Sharma, Md Khalid Anwer, Deepak Kaushik, Vineet Mittal, Sridevi Chigurupati, Pritam Babu Sharma, Lotfi Aleya, Celia Vargas-de-la-Cruz, Md Tanvir Kabi. Anti-migraine activity of freeze-dried latex obtained from Calotropis gigantea Linn. Environmental science and pollution research international. 2022-01-04. PMID:34981370. |
anti-migraine effect of calotropis gigantea freeze-dried latex by inhibition of dopamine and serotonin receptors (d1 and d2: dopamine receptors; 5-ht: serotonin receptors); yellow color represents serotonergic, and blue color indicates dopaminergic neurons. |
2022-01-04 |
2023-08-13 |
Not clear |
| Carolina Ramos de Mendonça, Raul Manhães-de-Castro, Bárbara Juacy Rodrigues Costa de Santana, Luana Olegário da Silva, Ana Elisa Toscano, Omar Guzmán-Quevedo, Lígia Cristina Monteiro Galind. Effects of flavonols on emotional behavior and compounds of the serotonergic system: A preclinical systematic review. European journal of pharmacology. 2021-12-26. PMID:34954234. |
the results of this systematic review showed that flavonols have been reported to modify physiological aspects of the serotonergic system, increasing levels of serotonin and decreasing levels of its metabolite, 5-hydroxyindoleacetic acid (5-hiaa) and promoting antioxidant effects in encephalic regions. |
2021-12-26 |
2023-08-13 |
Not clear |
| Andrea S Grunst, Melissa L Grunst, Nicky Staes, Bert Thys, Rianne Pinxten, Marcel Een. Serotonin transporter (SERT) polymorphisms, personality and problem-solving in urban great tits. Scientific reports. vol 11. issue 1. 2021-12-21. PMID:34930949. |
genes in the serotonergic signaling pathway, including the serotonin transporter gene (sert), are candidates for affecting animal personality, cognition and fitness. |
2021-12-21 |
2023-08-13 |
Not clear |
| Munazzah Tasleem, Abdulwahed Alrehaily, Tahani M Almeleebia, Mohammad Y Alshahrani, Irfan Ahmad, Mohammed Asiri, Nadiyah M Alabdallah, Mohd Saee. Investigation of Antidepressant Properties of Yohimbine by Employing Structure-Based Computational Assessments. Current issues in molecular biology. vol 43. issue 3. 2021-12-10. PMID:34889886. |
conformational changes and fluctuations occurring during wild type and mutant serotonergic receptor, 5-hydroxytryptamine receptors 1a (5ht1a) and yohimbine were assessed by molecular dynamics md simulation studies. |
2021-12-10 |
2023-08-13 |
Not clear |
| Nirupa Goel, Tristan J Philippe, Judy Chang, Maya E Koblanski, Victor Via. Cellular and serotonergic correlates of habituated neuroendocrine responses in male and female rats. Psychoneuroendocrinology. vol 136. 2021-12-10. PMID:34891046. |
however, this process may be met by underlying sex differences in serotonergic control, given the respective roles for pre- and postsynaptic 5-ht 1 a receptors in mediating serotonin availability and signal transfer. |
2021-12-10 |
2023-08-13 |
rat |
| Tianle Zhu, Pan Gao, Jingjing Gao, Xi Liu, Hui Jiang, Xiansheng Zhan. The upregulation of tryptophan hydroxylase-2 expression is important for premature ejaculation treatment with the selective serotonin reuptake inhibitor. Andrology. 2021-12-07. PMID:34874128. |
although there was some evidence to suggest that the serotonergic system in the brain played an important role in premature ejaculation (pe), tryptophan hydroxylase-2 (tph2) is considered to be the key enzyme for the synthesis of 5-hydroxytryptamine (5-ht) and few studies have reported that brain tph2 is involved in the regulation of ejaculation. |
2021-12-07 |
2023-08-13 |
Not clear |
| Gordana Nedic Erjavec, Jasminka Bektic Hodzic, Senka Repovecki, Matea Nikolac Perkovic, Suzana Uzun, Oliver Kozumplik, Lucija Tudor, Ninoslav Mimica, Dubravka Svob Strac, Nela Piva. Alcohol-related phenotypes and platelet serotonin concentration. Alcohol (Fayetteville, N.Y.). vol 97. 2021-12-06. PMID:34530080. |
while searching for peripheral biomarkers of altered serotonergic (5-ht) function in alcohol dependence and alcohol-related behaviors, we determined a peripheral biomarker, i.e., platelet 5-ht concentration in a large group of caucasian subjects with alcohol dependence subdivided according to the presence of specific alcohol-related phenotypes and smoking status. |
2021-12-06 |
2023-08-13 |
human |
| Yohei Kawano, Maki Obana, Masashi Nagata, Yasunari Mano, Maho Katsuyama, Yuichiro Yamamoto, Ayako Maeda-Minami, Kenichi Negishi, Masamichi Takagi, Shuji Shimada, Takao Aoyam. European Journal of Pharmacology - Regular article the antiplatelet effect of mirtazapine is mediated by co-blocking 5-HT European journal of pharmacology. 2021-12-05. PMID:34818517. |
european journal of pharmacology - regular article the antiplatelet effect of mirtazapine is mediated by co-blocking 5-ht mirtazapine (mtz) is a noradrenergic and specific serotonergic antidepressant that has been associated with an increased risk of bleeding. |
2021-12-05 |
2023-08-13 |
Not clear |
| Fatemeh Hadi, Shayan Kashefinejad, Leila Kamalzadeh, Saba Hoobehfekr, Mohammadreza Shalbafa. Glutamatergic medications as adjunctive therapy for moderate to severe obsessive-compulsive disorder in adults: a systematic review and meta-analysis. BMC pharmacology & toxicology. vol 22. issue 1. 2021-12-03. PMID:34736541. |
serotonergic medications, particularly selective serotonin reuptake inhibitors (ssris), are the first-line treatments for patients with ocd. |
2021-12-03 |
2023-08-13 |
Not clear |
| Eun-Seon Yoo, Li Li, Lin Jia, Caleb C Lord, Charlotte E Lee, Shari G Birnbaum, Claudia R Vianna, Eric D Berglund, Kathryn A Cunningham, Yong Xu, Jong-Woo Sohn, Chen Li. Gα Cell reports. vol 37. issue 7. 2021-12-03. PMID:34788630. |
gα the anorexigenic effect of serotonergic compounds has largely been attributed to activation of serotonin 2c receptors (htr2cs). |
2021-12-03 |
2023-08-13 |
mouse |
| Jae Heon Kim, Young Soo Ahn, Yun Seob Son. Liberation of Serotonin Is Not Unaffected by Acetylcholine in Rat Hippocampus. International neurourology journal. vol 25. issue Suppl 2. 2021-11-30. PMID:34844394. |
the current research was conducted in order to explore the role of acetylcholine in serotonin liberation from sections of rat hippocampus in order to improve the comprehension of the relationship between cholinergic and serotonergic neurons. |
2021-11-30 |
2023-08-13 |
rat |
| Olga E Redina, Vladimir N Babenko, Dmitry A Smagin, Irina L Kovalenko, Anna G Galyamina, Natalia N Kudryavtsev. Correlation of Expression Changes between Genes Controlling 5-HT Synthesis and Genes Genes. vol 12. issue 11. 2021-11-29. PMID:34828419. |
correlation of expression changes between genes controlling 5-ht synthesis and genes midbrain raphe nuclei (mrns) contain a large number of serotonergic neurons associated with the regulation of numerous types of psychoemotional states and physiological processes. |
2021-11-29 |
2023-08-13 |
mouse |
| Mathilde Baudat, Anne R de Kort, Daniel L A van den Hove, Elbert A J Jooste. Early-life exposure to selective serotonin reuptake inhibitors: long-term effects on pain and affective comorbidities. The European journal of neuroscience. 2021-11-29. PMID:34841582. |
third, early-life selective serotonin reuptake inhibitor exposure alters serotonergic levels, transcription factors expression and brain derived neurotrophic factor levels, resulting in hyperconnectivity within the amygdala and the prefrontal cortex. |
2021-11-29 |
2023-08-13 |
Not clear |
| Miky Timothy, Paul M Forlan. Serotonin distribution in the brain of the plainfin midshipman: Substrates for vocal-acoustic modulation and a reevaluation of the serotonergic system in teleost fishes. The Journal of comparative neurology. vol 528. issue 18. 2021-11-25. PMID:32361985. |
serotonin distribution in the brain of the plainfin midshipman: substrates for vocal-acoustic modulation and a reevaluation of the serotonergic system in teleost fishes. |
2021-11-25 |
2023-08-13 |
Not clear |
| Miky Timothy, Paul M Forlan. Serotonin distribution in the brain of the plainfin midshipman: Substrates for vocal-acoustic modulation and a reevaluation of the serotonergic system in teleost fishes. The Journal of comparative neurology. vol 528. issue 18. 2021-11-25. PMID:32361985. |
while previous studies have described 5-ht distribution in various teleosts, serotonergic raphe subgroups in fish are not well defined and therefore remain problematic for cross-species comparisons. |
2021-11-25 |
2023-08-13 |
Not clear |
| William H Powell, Lucy E Annett, Ronan Depoortere, Adrian Newman-Tancredi, Mahmoud M Iravan. The selective 5-HT Naunyn-Schmiedeberg's archives of pharmacology. 2021-11-25. PMID:34821958. |
the selective 5-ht anxiety is amongst the commonest neuropsychiatric disorders, and there is a large body of evidence to suggest that abnormalities in serotonergic function are involved in its pathogenesis. |
2021-11-25 |
2023-08-13 |
Not clear |
| H Bottemanne, A Claret, P Fossat. [Ketamine, psilocybin, and rapid acting antidepressant: new promise for psychiatry?] L'Encephale. vol 47. issue 2. 2021-11-24. PMID:33190819. |
the success of ketamine in the management of depressive disorders has provoked a renewed interest in hallucinogenic substances such as psilocybin targeting the serotonergic signaling 5ht |
2021-11-24 |
2023-08-13 |
Not clear |
| Meira Maria Forcelini Machado, Renata Mancini Banin, Fernanda Malanconi Thomaz, Iracema Senna de Andrade, Valter Tadeu Boldarine, Jéssica de Souza Figueiredo, Bruna Kelly Sousa Hirata, Lila Missae Oyama, João Henrique Ghilardi Lago, Eliane Beraldi Ribeiro, Mônica Marques Telle. Ginkgo biloba Extract (GbE) Restores Serotonin and Leptin Receptor Levels and Plays an Antioxidative Role in the Hippocampus of Ovariectomized Rats. Molecular neurobiology. vol 58. issue 6. 2021-11-24. PMID:33492645. |
since ginkgo biloba extract (gbe) was reported to improve the hypothalamic serotonergic system of ovariectomized (ovx) rats, the present study aimed to verify the gbe effects on hippocampal oxidative stress, inflammation, and levels of the serotonin transporter (5-htt), and both the serotonin (5-ht |
2021-11-24 |
2023-08-13 |
rat |