| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Elizabeth A Bartlett, Francesca Zanderigo, Denise Shieh, Jeffrey Miller, Patrick Hurley, Harry Rubin-Falcone, Maria A Oquendo, M Elizabeth Sublette, R Todd Ogden, J John Man. Serotonin transporter binding in major depressive disorder: impact of serotonin system anatomy. Molecular psychiatry. 2022-04-29. PMID:35487966. |
we now investigate 5-htt binding in mdd in two novel ways: (1) use of a 5-htt tract-based analysis examining binding along serotonergic axons; and (2) using the copenhagen university hospital neurobiology research unit (nru) 5-ht atlas, based on brain-wide binding patterns of multiple serotonin receptor types. |
2022-04-29 |
2023-08-13 |
Not clear |
| Merav Tauber, Yair Ben Chai. The activity of the serotonergic 5-HT The Journal of biological chemistry. 2022-04-26. PMID:35469922. |
the activity of the serotonergic 5-ht g protein-coupled receptors (gpcrs) are known to play a key role in many cellular signal transduction processes, including those mediating serotonergic signaling in the nervous system. |
2022-04-26 |
2023-08-13 |
xenopus_laevis |
| Juan Wang, Xiaoyan Gao, Pengcheng Gao, Jiwen Li. A Cross-Sectional Study on the Relationship Among Cytokines, 5-HT2A Receptor Polymorphisms, and Sleep Quality of Non-manual Workers in Xinjiang, China. Frontiers in psychiatry. vol 13. 2022-04-25. PMID:35463508. |
furthermore, the serotonergic system is also one of the essential components of airway relaxation during sleep, especially the serotonin 2a receptor (5-htr2a) type that plays an important role in the sleep-wake process. |
2022-04-25 |
2023-08-13 |
Not clear |
| Che Yu Kuo, Kao Chin Chen, I Hui Lee, Huai-Hsuan Tseng, Nan Tsing Chiu, Po See Chen, Yen Kuang Yang, Wei Hung Chan. Serotonin Modulates the Correlations between Obsessive-compulsive Trait and Heart Rate Variability in Normal Healthy Subjects: A SPECT Study with [ Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology. vol 20. issue 2. 2022-04-25. PMID:35466098. |
serotonin modulates the correlations between obsessive-compulsive trait and heart rate variability in normal healthy subjects: a spect study with [ the impact of serotonergic system on obsessive-compulsive disorder (ocd) is well studied. |
2022-04-25 |
2023-08-13 |
human |
| Brandon Hammond, Lacey Straube, Benjamin Cob. Expectant management of a parturient with serotonin syndrome: A case report. Obstetric medicine. vol 15. issue 1. 2022-04-21. PMID:35444731. |
serotonin syndrome is a potentially fatal condition caused by central nervous system serotonergic overactivity. |
2022-04-21 |
2023-08-13 |
Not clear |
| Guzel Musabirova, Oskar Engberg, Ankur Gupta, Debsankar Saha Roy, Sudipta Maiti, Daniel Huste. Serotonergic drugs modulate the phase behavior of complex lipid bilayers. Biochimie. 2022-04-21. PMID:35447219. |
here, we investigated if serotonergic drugs containing the pharmacophore from serotonin would also modulate phase behavior in lipid membranes in a similar fashion. |
2022-04-21 |
2023-08-13 |
Not clear |
| Vivian B Neis, Isabel Werle, Morgana Moretti, Priscila B Rosa, Anderson Camargo, Yasmim de O Dalsenter, Nicolle Platt, Axel F Rosado, William D Engel, Gudrian Ricardo L de Almeida, Ingrid Selhorst, Alcir Luiz Dafre, Ana Lúcia S Rodrigue. Involvement of serotonergic neurotransmission in the antidepressant-like effect elicited by cholecalciferol in the chronic unpredictable stress model in mice. Metabolic brain disease. 2022-04-18. PMID:35435610. |
moreover, the administration of p-chlorophenylalanine methyl ester (pcpa - 100 mg/kg, i.p., for 4 days, a selective inhibitor of tryptophan hydroxylase, involved in the serotonin synthesis) abolished the antidepressant-like effect of cholecalciferol and fluoxetine in the tail suspension test, demonstrating the involvement of serotonergic system. |
2022-04-18 |
2023-08-13 |
mouse |
| Elze R Timmers, Débora E Peretti, Marenka Smit, Bauke M de Jong, Rudi A J O Dierckx, Anouk Kuiper, Tom J de Koning, David Vállez García, Marina A J Tijsse. Serotonergic system in vivo with [ Scientific reports. vol 12. issue 1. 2022-04-16. PMID:35428769. |
serotonergic system in vivo with [ gtp-cyclohydrolase deficiency in dopa-responsive dystonia (drd) patients impairs the biosynthesis of dopamine, but also of serotonin. |
2022-04-16 |
2023-08-13 |
Not clear |
| Yanli Guo, Jing Zhao, Qinglei Xu, Siyuan Gao, Mingzheng Liu, Chunlei Zhang, Allan P Schinckel, Bo Zho. Identification of Functional Single Nucleotide Polymorphisms in the Porcine SLC6A4 Gene Associated with Aggressive Behavior in Weaned Pigs after Mixing. Journal of animal science. 2022-04-14. PMID:35419600. |
variation in genes of the serotonergic system influence aggressive behavior by affecting serotonin levels in the central and cortical nervous system. |
2022-04-14 |
2023-08-13 |
Not clear |
| F Bavato, S Stamatakos, C M Yde Ohki, E Seifritz, P Romualdi, E Grünblatt, B B Quedno. Brain-derived neurotrophic factor protects serotonergic neurons against 3,4-methylenedioxymethamphetamine ("Ecstasy") induced cytoskeletal damage. Journal of neural transmission (Vienna, Austria : 1996). 2022-04-14. PMID:35420371. |
3,4-methylenedioxymethamphetamine (mdma, "ecstasy") use has been linked to persistent alterations of the brain serotonergic (5-ht) system in animal and human studies, but the molecular underpinnings are still unclear. |
2022-04-14 |
2023-08-13 |
human |
| Arshan Khan, Abdelilah Lahmar, Haris Asif, Muhammad Haseeb, Kelash Ra. Serotonin Syndrome Precipitated by the Use of Cocaine and Fentanyl. Cureus. vol 14. issue 3. 2022-04-11. PMID:35399456. |
serotonin syndrome (ss) is a condition that occurs following the administration of serotonergic drugs. |
2022-04-11 |
2023-08-13 |
Not clear |
| Yu Han, Meng Zhang, Jiahui Duan, Leyi Li, Jinge Du, Hui Cheng, Sheng Zhang, Yanhui Zhai, Xinglan An, Qi Li, Xueming Zhang, Ziyi Li, Bo Tan. Maternal Prepregnancy 5-Hydroxytryptamine Exposure Affects the Early Development of the Fetus. Frontiers in physiology. vol 13. 2022-04-04. PMID:35370795. |
in recent decades, the increasing incidence of depression has contributed to an increase in the use of serotonergic drugs, such as antidepressants, which predisposes humans to serotonin syndrome. |
2022-04-04 |
2023-08-13 |
mouse |
| Søren Vinther Larsen, Brice Ozenne, Kristin Köhler-Forsberg, Asbjørn Seenithamby Poulsen, Vibeke Høyrup Dam, Claus Svarer, Gitte Moos Knudsen, Martin Balslev Jørgensen, Vibe Gedso Frokjae. The Impact of Hormonal Contraceptive Use on Serotonergic Neurotransmission and Antidepressant Treatment Response: Results From the NeuroPharm 1 Study. Frontiers in endocrinology. vol 13. 2022-04-01. PMID:35360055. |
this might be related to hc's effect on the serotonergic brain system as suggested by recent cross-sectional data from our group, which show that healthy oral contraceptive (oc) users relative to non-users have lower cerebral serotonin 4 receptor (5-ht4r) levels. |
2022-04-01 |
2023-08-13 |
Not clear |
| Sun Mi Gu, Eunhye Yu, Young Eun Kim, Seong Shoon Yoon, Dohyun Lee, Jin Tae Hong, Jaesuk Yu. Peroxiredoxin 6 Overexpression Induces Anxiolytic and Depression-Like Behaviors by Regulating the Serotonergic Pathway in Mice. Biomolecules & therapeutics. 2022-03-31. PMID:35354689. |
our findings provide novel insights into the role of prdx6 in 5-ht synthesis and suggest that prdx6 overexpression can induce depression-like behaviors via downregulation of the serotonergic neuronal system. |
2022-03-31 |
2023-08-13 |
mouse |
| Mithula Sivasaravanaparan, Louise Ørum Olesen, Maurizio Severino, Maurizio Christian Ulrich von Linstow, Kate Lykke Lambertsen, Jan Bert Gramsbergen, Jørgen Hasselstrøm, Athanasios Metaxas, Ove Wiborg, Bente Finse. Efficacy of Chronic Paroxetine Treatment in Mitigating Amyloid Pathology and Microgliosis in APPSWE/PS1ΔE9 Transgenic Mice. Journal of Alzheimer's disease : JAD. 2022-03-28. PMID:35342093. |
modulation of serotonergic signaling by treatment with selective serotonin reuptake inhibitors (ssris) has been suggested to mitigate amyloid-β (aβ) pathology in alzheimer's disease, in addition to exerting an anti-depressant action. |
2022-03-28 |
2023-08-13 |
mouse |
| b' Bar\\xc4\\xb1\\xc5\\x9f Yilba\\xc5\\x9. Restless Legs Syndrome Due to the Use of Trazodone: A Case Report. Turk psikiyatri dergisi = Turkish journal of psychiatry. vol 33. issue 1. 2022-03-28. PMID:35343583.' |
many case reports have demonstrated that using antidepressants and especially the selective serotonin reuptake inhibitors (ssris), and the noradrenergic and specific serotonergic antidepresants mirtazapine and mianserin can lead to restless legs syndrome (rls). |
2022-03-28 |
2023-08-13 |
Not clear |
| Enav Z Zusman, Alekhya Lavu, Colleen Pawliuk, Jodi Pawluski, Sarah M Hutchison, Robert W Platt, Tim F Oberlande. Associations Between Prenatal Exposure to Serotonergic Medications and Biobehavioral Stress Regulation: Protocol for a Systematic Review and Meta-analysis. JMIR research protocols. vol 11. issue 3. 2022-03-28. PMID:35343913. |
serotonergic antidepressants readily cross the placenta and the fetal blood-brain barrier, altering central synaptic serotonin signaling and potentially altering serotonin levels in the developing fetal brain. |
2022-03-28 |
2023-08-13 |
Not clear |
| Rumin Zhang, Dandan Li, Huiling Mao, Xiaonan Wei, MingDong Xu, Shengnan Zhang, Yunlu Jiang, Chunmei Wang, Qing Xin, Xiaoyu Chen, Guorong Li, Bingyuan Ji, Maocai Yan, Xin Cai, Bo Dong, Harpal S Randeva, Chuanxin Liu, Jing Che. Disruption of 5-hydroxytryptamine 1A receptor and orexin receptor 1 heterodimer formation affects novel G protein-dependent signaling pathways and has antidepressant effects in vivo. Translational psychiatry. vol 12. issue 1. 2022-03-26. PMID:35338110. |
increasing evidence supports the importance of serotonergic and orexin-producing neurons in numerous physiological processes, possibly via a crucial interaction between 5-hydroxytryptamine 1a receptor (5-ht1ar) and orexin receptor 1 (ox1r). |
2022-03-26 |
2023-08-13 |
Not clear |
| Alyce M Martin, Lauren A Jones, Lai Wei, Nick J Spencer, Kenton M Sanders, Seungil Ro, Damien J Keatin. Distinguishing the contributions of neuronal and mucosal serotonin in the regulation of colonic motility. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2022-03-21. PMID:35313053. |
significantly lower amounts of 5-ht are made by other peripheral tissues and serotonergic neurons within the enteric nervous system (ens). |
2022-03-21 |
2023-08-13 |
Not clear |
| Hilary F Armstrong, David Lederer, Gina S Lovasi, Grant Hiura, Corey E Ventetuolo, RGraham Bar. Selective serotonin reuptake inhibitors and lung function in the multi-ethnic study of atherosclerosis lung study. Respiratory medicine. vol 196. 2022-03-20. PMID:35306387. |
selective serotonin reuptake inhibitors (ssris) have anti-inflammatory and serotonergic effects that may improve lung function. |
2022-03-20 |
2023-08-13 |
human |