| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xinmei Wang, Danielle Kuban-Johnston, Pablo Lapuerta, Carla M R Lacerd. Telotristat ethyl reverses myxomatous changes in mice mitral valves. Frontiers in cardiovascular medicine. vol 9. 2022-08-22. PMID:35990981. |
in addition to similarities between naturally occurring and serotonergic valve degeneration, an increasing body of evidence has recently suggested that serotonin signaling is a regulator of degenerative valvulopathies. |
2022-08-22 |
2023-08-14 |
mouse |
| Rachel Gray, Arnold Moore Iii, Fiona Berry, Farzana Afroze, Divya Cherukupall. Serotonin Syndrome after PACU Administration of Tramadol and Meperidine. Turkish journal of anaesthesiology and reanimation. vol 50. issue 4. 2022-08-18. PMID:35979980. |
serotonin syndrome was eventually diagnosed in the context of the symptoms following the administration of 2 serotonergic agents. |
2022-08-18 |
2023-08-14 |
Not clear |
| Rachel Gray, Arnold Moore Iii, Fiona Berry, Farzana Afroze, Divya Cherukupall. Serotonin Syndrome after PACU Administration of Tramadol and Meperidine. Turkish journal of anaesthesiology and reanimation. vol 50. issue 4. 2022-08-18. PMID:35979980. |
this case is one of the first published reports of serotonin syndrome resulting from an interaction between tramadol and meperidine, highlighting the importance of constant vigilance in the perioperative period when serotonergic agents are involved. |
2022-08-18 |
2023-08-14 |
Not clear |
| Nina K Popova, Anton S Tsybko, Vladimir S Naumenk. The Implication of 5-HT Receptor Family Members in Aggression, Depression and Suicide: Similarity and Difference. International journal of molecular sciences. vol 23. issue 15. 2022-08-12. PMID:35955946. |
being different multifactorial forms of psychopathology, aggression, depression and suicidal behavior, which is considered to be violent aggression directed against the self, have principal neurobiological links: preclinical and clinical evidence associates depression, aggression and suicidal behavior with dysregulation in central serotonergic (5-ht) neurotransmission. |
2022-08-12 |
2023-08-14 |
Not clear |
| Andréa V Maglione, Bruna P P do Nascimento, Miriam O Ribeiro, Talytha J L de Souza, Renata E C da Silva, Monica A Sato, Carlos A A Penatti, Luiz R G Britto, Janaina S de Souza, Rui M B Maciel, Rodrigo Rodrigues da Conceição, Roberto Laureano-Melo, Gisele Giannocc. Triiodothyronine Treatment reverses Depression-Like Behavior in a triple-transgenic animal model of Alzheimer's Disease. Metabolic brain disease. 2022-08-11. PMID:35951206. |
therefore, our findings suggest that in an ad mouse model, t3 supplementation promotes improvements in depression-like behavior, through the modulation of the serotonergic related genes involved in the transmission mediated by 5ht1a receptors and serotonin reuptake, and attenuated disease progression. |
2022-08-11 |
2023-08-14 |
mouse |
| Alena B Zuzina, Pavel M Balaba. Contribution of histone acetylation to the serotonin-mediated long-term synaptic plasticity in terrestrial snails. Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology. 2022-08-09. PMID:35943582. |
here we investigated effects of serotonin, histone deacetylases inhibitors sodium butyrate and trichostatin a, and a serotonergic receptor inhibitor methiothepin on long-term potentiation of synaptic responses in vitro. |
2022-08-09 |
2023-08-14 |
Not clear |
| Ryo Yamamoto, Tetsufumi Ito, Takafumi Furuyama, Munenori Ono, Nobuo Kat. 5-HT and α-m-5-HT attenuate excitatory synaptic transmissions onto the lateral amygdala principal neurons via presynaptic 5-HT Biochemical and biophysical research communications. vol 624. 2022-08-06. PMID:35932576. |
5-ht and α-m-5-ht attenuate excitatory synaptic transmissions onto the lateral amygdala principal neurons via presynaptic 5-ht accumulating evidence suggests that the serotonergic (5-ht) system in the amygdala has significant effects on affective states. |
2022-08-06 |
2023-08-14 |
rat |
| Mario de la Fuente Revenga, Alaina M Jaster, John McGinn, Gabriella Silva, Somdatta Saha, Javier González-Maes. Tolerance and Cross-Tolerance among Psychedelic and Nonpsychedelic 5-HT ACS chemical neuroscience. 2022-07-28. PMID:35900876. |
tolerance and cross-tolerance among psychedelic and nonpsychedelic 5-ht classical psychedelics represent a subgroup of serotonergic psychoactive substances characterized by their distinct subjective effects on the human psyche. |
2022-07-28 |
2023-08-14 |
human |
| Antonella Comitato, Enza Lacivita, Marcello Leopoldo, Rita Bardon. 5-HT Frontiers in molecular neuroscience. vol 15. 2022-07-25. PMID:35875663. |
5-ht serotonergic receptors of the 5-ht |
2022-07-25 |
2023-08-14 |
Not clear |
| Ruchi Sharma, Rajeev K Singla, Subhadip Banerjee, Baivab Sinha, Bairong Shen, Rohit Sharm. Role of Shankhpushpi (Convolvulus pluricaulis) in Neurological Disorders: An Umbrella Review Covering Evidence from Ethnopharmacology to Clinical Studies. Neuroscience and biobehavioral reviews. 2022-07-25. PMID:35878793. |
network pharmacology results indicate that compounds from c. pluricaulis interact with various proteins, neuro synapses, signaling pathways, and serotonergic synapse which plays a crucial role in neurotransmission, alzheimer's disease, long-term depression, addictions to alcohol, cognitive disorders, psychological conditions, and increasing serotonin concentration in synapses. |
2022-07-25 |
2023-08-14 |
Not clear |
| James M Shine, Claire O'Callaghan, Ishan C Walpola, Gabriel Wainstein, Natasha Taylor, Jaan Aru, Bryce Huebner, Yohan J Joh. Understanding the effects of serotonin in the brain through its role in the gastrointestinal tract. Brain : a journal of neurology. 2022-07-23. PMID:35869620. |
fascinatingly, despite clear links between serotonergic function and cognitive capacities as diverse as reward processing, exploration, and the psychedelic experience, over 95% of the serotonin in the body is released in the gastrointestinal tract, where it controls digestive muscle contractions (peristalsis). |
2022-07-23 |
2023-08-14 |
Not clear |
| James M Shine, Claire O'Callaghan, Ishan C Walpola, Gabriel Wainstein, Natasha Taylor, Jaan Aru, Bryce Huebner, Yohan J Joh. Understanding the effects of serotonin in the brain through its role in the gastrointestinal tract. Brain : a journal of neurology. 2022-07-23. PMID:35869620. |
here, we argue that framing neural serotonin as a rostral extension of the gastrointestinal serotonergic system dissolves much of the mystery associated with the central serotonergic system. |
2022-07-23 |
2023-08-14 |
Not clear |
| James M Shine, Claire O'Callaghan, Ishan C Walpola, Gabriel Wainstein, Natasha Taylor, Jaan Aru, Bryce Huebner, Yohan J Joh. Understanding the effects of serotonin in the brain through its role in the gastrointestinal tract. Brain : a journal of neurology. 2022-07-23. PMID:35869620. |
specifically, we outline that central serotonin activity mimics the effects of a digestion/satiety circuit mediated by hypothalamic control over descending serotonergic nuclei in the brainstem. |
2022-07-23 |
2023-08-14 |
Not clear |
| James M Shine, Claire O'Callaghan, Ishan C Walpola, Gabriel Wainstein, Natasha Taylor, Jaan Aru, Bryce Huebner, Yohan J Joh. Understanding the effects of serotonin in the brain through its role in the gastrointestinal tract. Brain : a journal of neurology. 2022-07-23. PMID:35869620. |
this perspective sheds light on otherwise disparate capacities mediated by serotonin, and also helps to understand why there are such pervasive links between serotonergic pathology and the symptoms of psychiatric disorders. |
2022-07-23 |
2023-08-14 |
Not clear |
| Justin J Kavanagh, Janet L Taylo. Voluntary activation of muscle in humans: does serotonergic neuromodulation matter? The Journal of physiology. 2022-07-22. PMID:35864781. |
to gain insight into the serotonergic contributions to muscle activation in humans, pharmacological interventions have been employed to enhance the concentration of 5-ht in the central nervous system or activate selective 5-ht receptors. |
2022-07-22 |
2023-08-14 |
human |
| Pauline Bohne, Achim Volkmann, Martin K Schwarz, Melanie D Mar. Deletion of the P/Q-type calcium channel from serotonergic neurons drives male aggression in mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-07-19. PMID:35853721. |
serotonin (5-ht) plays a key role in the regulation of our emotions such as anxiety and aggression, but which molecules and mechanisms in the serotonergic system are involved in violent behavior is still unknown. |
2022-07-19 |
2023-08-14 |
mouse |
| Sarah T Eudaley, Shelby P Brooks, Leslie A Hamilto. Case Report: Possible Serotonin Syndrome in a Patient Taking Kratom and Multiple Serotonergic Agents. Journal of pharmacy practice. 2022-07-15. PMID:35840540. |
case report: possible serotonin syndrome in a patient taking kratom and multiple serotonergic agents. |
2022-07-15 |
2023-08-14 |
Not clear |
| Shicheng Zhang, He Chen, Chengwei Zhang, Ying Yang, Petr Popov, Jing Liu, Brian E Krumm, Can Cao, Kuglae Kim, Yan Xiong, Vsevolod Katritch, Brian K Shoichet, Jian Jin, Jonathan F Fay, Bryan L Rot. Inactive and active state structures template selective tools for the human 5-HT Nature structural & molecular biology. 2022-07-14. PMID:35835867. |
there are 12 serotonergic g protein-coupled receptor members encoded in the human genome, of which the 5-hydroxytryptamine (5-ht) |
2022-07-14 |
2023-08-14 |
human |
| Ian Lancaster, Jeffrey Steinhoff, Jose Mosco-Guzman, Deep Pate. Serotonin Syndrome Induced Tako-Tsubo Syndrome. Case reports in cardiology. vol 2022. 2022-07-07. PMID:35795821. |
serotonin syndrome is a life-threatening condition associated with increased serotonergic activity in the central nervous system (cns). |
2022-07-07 |
2023-08-14 |
Not clear |
| Kei-Ichi Katayama, Naoko Morimura, Katsunori Kobayashi, Danielle Corbett, Takehito Okamoto, Veravej G Ornthanalai, Hayato Matsunaga, Wakako Fujita, Yoshifumi Matsumoto, Takumi Akagi, Tsutomu Hashikawa, Kazuyuki Yamada, Niall P Murphy, Soichi Nagao, Jun Arug. Slitrk2 deficiency causes hyperactivity with altered vestibular function and serotonergic dysregulation. iScience. vol 25. issue 7. 2022-07-05. PMID:35789858. |
a serotonin metabolite was increased in the hippocampus and amygdala, and serotonergic neurons in the raphe nuclei were decreased in slitrk2 ko mice. |
2022-07-05 |
2023-08-14 |
mouse |