| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| James R Docherty, Hadeel A Alsufyan. Pharmacology of Drugs Used as Stimulants. Journal of clinical pharmacology. vol 61 Suppl 2. 2021-11-01. PMID:34396557. |
psychostimulant, cardiovascular, and temperature actions of stimulants involve adrenergic (norepinephrine), dopaminergic (dopamine), and serotonergic (serotonin) pathways. |
2021-11-01 |
2023-08-13 |
Not clear |
| Yu Miyahara, Hideki Funahashi, Ayaka Haruta-Tsukamoto, Yoichiro Kogoh, Anna Kanemaru-Kawazoe, Toshikazu Nishimori, Yasushi Ishid. Roles of 5-HT European journal of pharmacology. vol 911. 2021-11-01. PMID:34555396. |
roles of 5-ht the roles of serotonin (5-ht) and/or noradrenaline in acute pruriceptive processing have been demonstrated using antidepressants, such as milnacipran, a serotonin and noradrenaline reuptake inhibitor, and mirtazapine, a noradrenergic and specific serotonergic antidepressant; however, the involvement of 5-ht in acute pruriceptive processing has not yet been elucidated in detail. |
2021-11-01 |
2023-08-13 |
Not clear |
| Jeong-Hee Kim, Young-Don Son, Hang-Keun Kim, Jong-Hoon Ki. Association Between Lack of Insight and Prefrontal Serotonin Transporter Availability in Antipsychotic-Free Patients with Schizophrenia: A High-Resolution PET Study with [ Neuropsychiatric disease and treatment. vol 17. 2021-10-30. PMID:34707358. |
association between lack of insight and prefrontal serotonin transporter availability in antipsychotic-free patients with schizophrenia: a high-resolution pet study with [ previous studies suggested a link between serotonergic neurotransmission and impaired insight in schizophrenia. |
2021-10-30 |
2023-08-13 |
Not clear |
| Omar Hernández-González, Andrea Mondragón-García, Salvador Hernández-López, Diego E Castillo-Rolon, Gabina Arenas-López, Dagoberto Tapia, Stefan Mihailesc. Mechanisms of stimulatory effects of mecamylamine on the dorsal raphe neurons. Brain research bulletin. vol 164. 2021-10-29. PMID:32910991. |
previous studies showed that mecamylamine a noncompetitive and nonspecific blocker of nicotinic acetylcholine receptors (nachrs), stimulates the activity of the dorsal raphe nucleus (drn) serotonergic neurons and drn serotonin (5-ht) release. |
2021-10-29 |
2023-08-13 |
rat |
| Tudor M Ionescu, Mario Amend, Rakibul Hafiz, Bharat B Biswal, Andreas Maurer, Bernd J Pichler, Hans F Wehrl, Kristina Herfer. Striatal and prefrontal D2R and SERT distributions contrastingly correlate with default-mode connectivity. NeuroImage. vol 243. 2021-10-29. PMID:34428573. |
the aim of this study was elucidating interactions between dopamine d2 receptors (d2r) and serotonin transporter (sert) availabilities in the striatum (cpu) and medial prefrontal cortex (mpfc), two of the main dopaminergic and serotonergic projection areas, and the default-mode network. |
2021-10-29 |
2023-08-13 |
rat |
| Michele Protti, Roberto Mandrioli, Camilla Marasca, Andrea Cavalli, Alessandro Serretti, Laura Mercolin. New-generation, non-SSRI antidepressants: Drug-drug interactions and therapeutic drug monitoring. Part 2: NaSSAs, NRIs, SNDRIs, MASSAs, NDRIs, and others. Medicinal research reviews. vol 40. issue 5. 2021-10-28. PMID:32285503. |
in this second part of the review, focused on new-generation antidepressants not included among selective serotonin reuptake inhibitors, the following classes are considered: noradrenergic and selective serotonergic antidepressants; norepinephrine reuptake inhibitors; serotonin, norepinephrine and dopamine reuptake inhibitors; melatonergic agonists and selective serotonergic antagonists; norepinephrine and dopamine reuptake inhibitors; and so forth. |
2021-10-28 |
2023-08-13 |
Not clear |
| Antonio Inserra, Danilo De Gregorio, Gabriella Gobb. Psychedelics in Psychiatry: Neuroplastic, Immunomodulatory, and Neurotransmitter Mechanisms. Pharmacological reviews. vol 73. issue 1. 2021-10-28. PMID:33328244. |
here, we discuss the main known neurobiological therapeutic mechanisms of psychedelics, which are thought to be mediated by the effects of these compounds on the serotonergic (via 5-ht |
2021-10-28 |
2023-08-13 |
Not clear |
| Yoshiyuki Mishima, Shunji Ishihar. Enteric Microbiota-Mediated Serotonergic Signaling in Pathogenesis of Irritable Bowel Syndrome. International journal of molecular sciences. vol 22. issue 19. 2021-10-28. PMID:34638577. |
the synthesis of 5-ht in intestinal enterochromaffin cells and host serotonergic signaling is regulated by enteric resident microbiota. |
2021-10-28 |
2023-08-13 |
Not clear |
| Vincent Martin, Lionel Mathieu, Jorge Diaz, Haysam Salman, Jeanine Alterio, Caroline Chevarin, Laurence Lanfumey, Michel Hamon, Mark C Austin, Michèle Darmon, Craig A Stockmeier, Justine Masso. Key role of the 5-HT1A receptor addressing protein Yif1B in serotonin neurotransmission and SSRI treatment. Journal of psychiatry & neuroscience : JPN. vol 45. issue 5. 2021-10-26. PMID:32459080. |
mechanisms by which the function of 5-ht1ar (expressed as an autoreceptor in serotonergic raphe neurons and as a heteroreceptor in serotonin [5-ht] projection areas) is altered include regulation of its expression, but 5-ht1ar trafficking may also be involved. |
2021-10-26 |
2023-08-13 |
Not clear |
| Marilia Gougoulaki, Glyn Lewis, David J Nutt, Tim J Peters, Nicola J Wiles, Gemma Lewi. Sex differences in depressive symptoms and tolerability after treatment with selective serotonin reuptake inhibitor antidepressants: Secondary analyses of the GENPOD trial. Journal of psychopharmacology (Oxford, England). vol 35. issue 8. 2021-10-26. PMID:33637001. |
differences in serotonergic neurotransmission could lead to sex differences in depressive symptoms and tolerability after treatment with selective serotonin reuptake inhibitors (ssris). |
2021-10-26 |
2023-08-13 |
Not clear |
| César Mateu, Marta Rodríguez-Arias, Isis Gil-Miravet, Ana Benito, José M Tomás, Gonzalo Har. The Association between a MAOB Variable Number Tandem Repeat Polymorphism and Cocaine and Opiate Addictions in Polyconsumers. Brain sciences. vol 11. issue 10. 2021-10-26. PMID:34679329. |
genetic analysis of the association between alcohol, cocaine, and opiate addiction and variable number tandem repeat (vntr) polymorphisms in monoamine oxidase b (maob) and serotonergic 5-hydroxytryptamine (serotonin) receptor 1b and 2c (htr1b 21 and htr2c) pathway genes was performed in a sample of 302 polyconsumers. |
2021-10-26 |
2023-08-13 |
Not clear |
| Wenlu Pan, Jing Pan, Yan Zhao, Hongzheng Zhang, Jie Tan. Serotonin Transporter Defect Disturbs Structure and Function of the Auditory Cortex in Mice. Frontiers in neuroscience. vol 15. 2021-10-26. PMID:34690685. |
serotonin transporter (sert) modulates the level of 5-ht and significantly affects the activity of serotonergic neurons in the central nervous system. |
2021-10-26 |
2023-08-13 |
mouse |
| Wankupar Wankhar, Donkupar Syiem, Careen Liza Pakyntein, Daiahun Thabah, Shelareen Ediemi Sun. Effect of 5-HT Behavioural brain research. vol 393. 2021-10-25. PMID:32579979. |
using this animal model, we have attempted to understand the serotonergic system in the hippocampus and prefrontal cortex, while using the 5-ht |
2021-10-25 |
2023-08-13 |
Not clear |
| Edoardo Rosario de Natale, Heather Wilson, Marios Politi. Serotonergic imaging in Parkinson's disease. Progress in brain research. vol 261. 2021-10-22. PMID:33785134. |
future studies of imaging serotonergic molecular targets will better clarify the importance of serotonergic pathology in pd, including progression of pathology, target-identification for pharmacotherapy, and relevance to endogenous synaptic serotonin levels. |
2021-10-22 |
2023-08-13 |
Not clear |
| Luisa Ugedo, Philippe De Deurwaerdèr. Serotonergic control of the glutamatergic neurons of the subthalamic nucleus. Progress in brain research. vol 261. 2021-10-22. PMID:33785138. |
here, we describe this serotonergic innervation and the nature of the regulation exerted by serotonin (5-hydroxytryptamine, 5-ht) on stn neuron activity. |
2021-10-22 |
2023-08-13 |
Not clear |
| Dongju Seo, Christopher J Patrick, Patrick J Kenneal. Role of Serotonin and Dopamine System Interactions in the Neurobiology of Impulsive Aggression and its Comorbidity with other Clinical Disorders. Aggression and violent behavior. vol 13. issue 5. 2021-10-20. PMID:19802333. |
specifically, serotonin hypofunction may represent a biochemical trait that predisposes individuals to impulsive aggression, with dopamine hyperfunction contributing in an additive fashion to the serotonergic deficit. |
2021-10-20 |
2023-08-12 |
Not clear |
| Eliane Proulx, Edwin J Young, Lucy R Osborne, Evelyn K Lamb. Enhanced prefrontal serotonin 5-HT(1A) currents in a mouse model of Williams-Beuren syndrome with low innate anxiety. Journal of neurodevelopmental disorders. vol 2. issue 2. 2021-10-20. PMID:20585377. |
our finding that 5-ht(1a)-mediated responses are selectively enhanced in layer v pyramidal neurons of gtf2ird1(-/-) mice gives insight into the cellular mechanisms that underlie reduced innate anxiety and increased sociability in these mice, and may be relevant to the low social anxiety and disinhibition in patients with wbs and their sensitivity to serotonergic medicines. |
2021-10-20 |
2023-08-12 |
mouse |
| Zahra Ghasemzadeh, Masoud Seddighfar, Sakineh Alijanpour, Ameneh Rezayo. Ventral tegmental area serotonin 5-HT Physiology & behavior. vol 239. 2021-10-20. PMID:34242672. |
ventral tegmental area serotonin 5-ht the present study examined the role of ventral tegmental area (vta) serotonergic 5ht |
2021-10-20 |
2023-08-13 |
Not clear |
| Mafdy N Bast. Postoperative Serotonin Syndrome Following Methylene Blue Administration for Vasoplegia After Cardiac Surgery: A Case Report and Review of the Literature. Seminars in cardiothoracic and vascular anesthesia. vol 25. issue 1. 2021-10-19. PMID:32951524. |
serotonin syndrome is a potentially life-threatening condition associated with increased serotonergic activity in the central nervous system. |
2021-10-19 |
2023-08-13 |
Not clear |
| Gerald Sosla. Cardiovascular serotonergic system: Evolution, receptors, transporter, and function. Journal of experimental zoology. Part A, Ecological and integrative physiology. 2021-10-18. PMID:34662506. |
the serotonergic system, serotonin (5ht), serotonin transporter (sert), and serotonin receptors (5ht-x), is an evolutionarily ancient system that has clear physiological advantages to all life forms from bacteria to humans. |
2021-10-18 |
2023-08-13 |
Not clear |