| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F Schwaller, A H Kanellopoulos, M Fitzgeral. The developmental emergence of differential brainstem serotonergic control of the sensory spinal cord. Scientific reports. vol 7. issue 1. 2018-12-11. PMID:28533557. |
the developmental emergence of differential brainstem serotonergic control of the sensory spinal cord. |
2018-12-11 |
2023-08-13 |
rat |
| Jie Xie, Teng Zhao, Yaobo Li. Sonic hedgehog regulates the pathfinding of descending serotonergic axons in hindbrain in collaboration with Wnt5a and secreted frizzled-related protein 1. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 66. 2018-09-07. PMID:29196093. |
previous studies have demonstrated that both wnt5a and sonic hedgehog (shh) are involved in regulating the pathfinding of descending serotonergic (5-ht, 5-hydroxytryptamine) axons in an opposite manner in the brainstem. |
2018-09-07 |
2023-08-13 |
Not clear |
| Fiona M Bright, Roger W Byard, Robert Vink, David S Paterso. Normative distribution of substance P and its tachykinin neurokinin-1 receptor in the medullary serotonergic network of the human infant during postnatal development. Brain research bulletin. vol 137. 2018-08-31. PMID:29331576. |
we examined the normative distribution of sp and nk1r in the serotonergic (5-hydroxytryptamine, [5-ht]) network of the human infant medulla during postnatal development, to provide a baseline to facilitate future analysis of the sp/nk1r system and its interaction with 5-ht within pediatric brainstem disorders in early life. |
2018-08-31 |
2023-08-13 |
human |
| Philip H Siebler, Jared D Heinze, Drake M Kienzle, Matthew W Hale, Jodi L Lukkes, Nina C Donner, Jared M Kopelman, Orlando A Rodriguez, Christopher A Lowr. Acute Administration of the Nonpathogenic, Saprophytic Bacterium, Mycobacterium vaccae, Induces Activation of Serotonergic Neurons in the Dorsal Raphe Nucleus and Antidepressant-Like Behavior in Association with Mild Hypothermia. Cellular and molecular neurobiology. vol 38. issue 1. 2018-08-13. PMID:29134419. |
one mechanism through which immune activation may affect physiology and behavior is through actions on brainstem neuromodulatory systems, such as serotonergic systems. |
2018-08-13 |
2023-08-13 |
mouse |
| Philip H Siebler, Jared D Heinze, Drake M Kienzle, Matthew W Hale, Jodi L Lukkes, Nina C Donner, Jared M Kopelman, Orlando A Rodriguez, Christopher A Lowr. Acute Administration of the Nonpathogenic, Saprophytic Bacterium, Mycobacterium vaccae, Induces Activation of Serotonergic Neurons in the Dorsal Raphe Nucleus and Antidepressant-Like Behavior in Association with Mild Hypothermia. Cellular and molecular neurobiology. vol 38. issue 1. 2018-08-13. PMID:29134419. |
in experiment 2, the protocol was repeated, but with the aim of assessing c-fos expression in brainstem serotonergic neurons, assessed 90 min following exposure to forced swim (n = 32; n = 8 per group). |
2018-08-13 |
2023-08-13 |
mouse |
| Gordian Hamerla, Peter Kropp, Bianca Meyer, Alessandro Rocco, Tim P Jürgens, Uwe Walte. Midbrain raphe hypoechogenicity in migraineurs: An indicator for the use of analgesics but not triptans. Cephalalgia : an international journal of headache. vol 37. issue 11. 2018-06-12. PMID:27534670. |
introduction the involvement of the serotonergic system of the brainstem raphe in the pathogenesis of migraine is discussed. |
2018-06-12 |
2023-08-13 |
human |
| James H Fox, James E Hassell, Philip H Siebler, Mathew R Arnold, Andrew K Lamb, David G Smith, Heidi E W Day, Tessa M Smith, Emma M Simmerman, Alexander A Outzen, Kaley S Holmes, Christopher J Brazell, Christopher A Lowr. Preimmunization with a heat-killed preparation of Mycobacterium vaccae enhances fear extinction in the fear-potentiated startle paradigm. Brain, behavior, and immunity. vol 66. 2018-06-06. PMID:28888667. |
rats were euthanized on day 11 and brain tissue was sectioned for analysis of mrna expression for genes important in control of brain serotonergic signaling, including tph2, htr1a, slc6a4, and slc22a3, throughout the brainstem dorsal and median raphe nuclei. |
2018-06-06 |
2023-08-13 |
mouse |
| Ronald G Garcia, Richard L Lin, Jeungchan Lee, Jieun Kim, Riccardo Barbieri, Roberta Sclocco, Ajay D Wasan, Robert R Edwards, Bruce R Rosen, Nouchine Hadjikhani, Vitaly Napado. Modulation of brainstem activity and connectivity by respiratory-gated auricular vagal afferent nerve stimulation in migraine patients. Pain. vol 158. issue 8. 2018-05-01. PMID:28541256. |
regulation of activity and connectivity of brainstem and cortical regions involved in serotonergic and noradrenergic regulation and pain modulation may constitute an underlying mechanism supporting beneficial clinical outcomes for eravans applied for episodic migraine. |
2018-05-01 |
2023-08-13 |
Not clear |
| Marco A Vindas, Angelico Madaro, Thomas W K Fraser, Erik Höglund, Rolf E Olsen, Tore S Kristiansen, Øyvind Øverl. Uncontrollable chronic stress reduces growth disparities in farmed Atlantic salmon. Physiology & behavior. vol 179. 2018-05-01. PMID:28668622. |
furthermore, we found brain serotonergic signaling and corticotropic releasing factor binding protein expression were positively associated with brain stem serotonergic activity, which is consistent with fish showing a stress reactivity neurophysiological profile. |
2018-05-01 |
2023-08-13 |
Not clear |
| Oi Wan Wan, Eunju Shin, Bengt Mattsson, Dorian Caudal, Per Svenningsson, Anders Björklun. α-Synuclein induced toxicity in brain stem serotonin neurons mediated by an AAV vector driven by the tryptophan hydroxylase promoter. Scientific reports. vol 6. 2018-04-02. PMID:27211987. |
we studied the impact of α-synuclein overexpression in brainstem serotonin neurons using a novel vector construct where the expression of human wildtype α-synuclein is driven by the tryptophan hydroxylase promoter, allowing expression of α-synuclein at elevated levels, and with high selectivity, in serotonergic neurons. |
2018-04-02 |
2023-08-13 |
human |
| Yongzhi Xia, Dan Chen, Haijian Xia, Zhengbu Liao, Wenyuan Tang, Yi Ya. Serotonergic projections to lumbar levels and its plasticity following spinal cord injury. Neuroscience letters. vol 649. 2018-03-08. PMID:28396282. |
the descending serotonergic pathway, which originates in various populations of brainstem neurons, plays an important role in generating the rhythmic motor pattern associated with locomotor movement. |
2018-03-08 |
2023-08-13 |
mouse |
| Jabir Mohamed, Brian W Scot. Impaired Cardiorespiratory Function during Focal Limbic Seizures: A Role for Serotonergic Brainstem Nuclei. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 34. 2018-01-12. PMID:27559160. |
impaired cardiorespiratory function during focal limbic seizures: a role for serotonergic brainstem nuclei. |
2018-01-12 |
2023-08-13 |
Not clear |
| Satoshi Ansai, Hiroshi Hosokawa, Shingo Maegawa, Kiyoshi Naruse, Youhei Washio, Kenji Sato, Masato Kinoshit. Deficiency of Serotonin in Raphe Neurons and Altered Behavioral Responses in Tryptophan Hydroxylase 2-Knockout Medaka (Oryzias latipes). Zebrafish. vol 14. issue 6. 2018-01-05. PMID:28933662. |
teleost fish species have serotonergic neurons in the raphe nuclei of the brainstem; however, the role of 5-ht in the raphe neurons in teleost fish remains largely unknown. |
2018-01-05 |
2023-08-13 |
Not clear |
| Scott A Givan, Kevin J Cumming. Intermittent severe hypoxia induces plasticity within serotonergic and catecholaminergic neurons in the neonatal rat ventrolateral medulla. Journal of applied physiology (Bethesda, Md. : 1985). vol 120. issue 11. 2017-12-14. PMID:26968026. |
we hypothesized that 1) catecholaminergic neurons in the neonatal vlm are activated following ish, 2) this activation is compromised following an acute loss of brain stem 5-ht, and 3) ish induces cellular and/or transcriptomic plasticity within catecholaminergic and serotonergic neurons that are within or project to the vlm, respectively. |
2017-12-14 |
2023-08-13 |
rat |
| Yoshiyuki Numasawa, Takaaki Hattori, Sumio Ishiai, Zen Kobayashi, Tomoyuki Kamata, Minoru Kotera, Satoru Ishibashi, Nobuo Sanjo, Hidehiro Mizusawa, Takanori Yokot. Depressive disorder may be associated with raphe nuclei lesions in patients with brainstem infarction. Journal of affective disorders. vol 213. 2017-11-27. PMID:28278447. |
the ascending serotonergic system originates from the raphe nuclei in the brainstem. |
2017-11-27 |
2023-08-13 |
Not clear |
| P M MacFarlane, C A Mayer, D G Litvi. Microglia modulate brainstem serotonergic expression following neonatal sustained hypoxia exposure: implications for sudden infant death syndrome. The Journal of physiology. vol 594. issue 11. 2017-08-07. PMID:26659585. |
microglia modulate brainstem serotonergic expression following neonatal sustained hypoxia exposure: implications for sudden infant death syndrome. |
2017-08-07 |
2023-08-13 |
Not clear |
| Daniela Brunert, Yusuke Tsuno, Markus Rothermel, Michael T Shipley, Matt Wachowia. Cell-Type-Specific Modulation of Sensory Responses in Olfactory Bulb Circuits by Serotonergic Projections from the Raphe Nuclei. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 25. 2017-07-10. PMID:27335411. |
serotonergic neurons in the brainstem raphe nuclei densely innervate the olfactory bulb (ob), where they can modulate the initial representation and processing of olfactory information. |
2017-07-10 |
2023-08-13 |
mouse |
| Aline P Pansani, Diego B Colugnati, Carla A Scorza, Antonio-Carlos G de Almeida, Esper A Cavalheiro, Fulvio A Scorz. Furthering our understanding of SUDEP: the role of animal models. Expert review of neurotherapeutics. vol 16. issue 5. 2017-06-27. PMID:27029803. |
impairments on adenosinergic and serotonergic systems, brainstem spreading depolarization, seizure-activation of neural substrates related to cardiorespiratory control, altered autonomic control, and mutations on sodium and potassium channels are hypothesis suggested. |
2017-06-27 |
2023-08-13 |
Not clear |
| Ilya Ayzenberg, Ilias Nastos, Katrin Strassburger-Krogias, Mark Obermann, Ralf Gold, Christos Krogia. Hypoechogenicity of brainstem raphe nuclei is associated with increased attack frequency in episodic migraine. Cephalalgia : an international journal of headache. vol 36. issue 8. 2017-03-02. PMID:26566936. |
reduced echogenicity of the brainstem raphe nuclei (brn) was demonstrated in major depression, possibly indicating serotonergic dysfunction. |
2017-03-02 |
2023-08-13 |
Not clear |
| Melissa A Papesh, Laura M Hurle. Modulation of auditory brainstem responses by serotonin and specific serotonin receptors. Hearing research. vol 332. 2016-12-13. PMID:26688176. |
this is the first study to describe the effects of serotonin on abr responses across a wide range of stimulus frequencies and amplitudes, and it presents an important step in understanding how serotonergic modulation of auditory brainstem processing may contribute to modulation of auditory perception. |
2016-12-13 |
2023-08-13 |
mouse |