| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yara M R Müller, Lilianna B D Rivero, Márcia C Carvalho, Karoline Kobus, Marcelo Farina, Evelise M Nazar. Behavioral impairments related to lead-induced developmental neurotoxicity in chicks. Archives of toxicology. vol 82. issue 7. 2008-09-19. PMID:18157517. |
lead impregnation was observed in both mesencephalon and cerebellum and the cerebellar molecular layer presented higher lead deposition in comparison to granular layer and purkinje cells. |
2008-09-19 |
2023-08-12 |
Not clear |
| Yukiko Tomioka, Taisuke Miyazaki, Satoshi Taharaguchi, Saori Yoshino, Masami Morimatsu, Toshimitsu Uede, Etsuro Ono, Masahiko Watanab. Cerebellar pathology in transgenic mice expressing the pseudorabies virus immediate-early protein IE180. The European journal of neuroscience. vol 27. issue 8. 2008-07-01. PMID:18412631. |
here we identified profound abnormalities in adult ie180 transgenic mice, including malpositioning of purkinje cells (pcs), granule cells (gcs) and bergmann glia (bg), impaired dendritogenesis and synaptogenesis in pcs, disoriented bg fibers, absence of molecular layer interneurons, and increased apoptosis of neurons and glia. |
2008-07-01 |
2023-08-12 |
mouse |
| Guadalupe García-Alcocer, Carmen Mejía, Laura C Berumen, Ricardo Miledi, Ataúlfo Martínez-Torre. Developmental expression of glycine receptor subunits in rat cerebellum. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 26. issue 3-4. 2008-06-30. PMID:18339511. |
the alpha1-3 subunits had weak signals in the purkinje cells and molecular layer. |
2008-06-30 |
2023-08-12 |
rat |
| Satoru Ota, Kuniaki Tsuchiya, Midori Anno, Kazuhiro Niizato, Haruhiko Akiyam. Distribution of cerebello-olivary degeneration in idiopathic late cortical cerebellar atrophy: clinicopathological study of four autopsy cases. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 28. issue 1. 2008-05-21. PMID:18181834. |
in all four cases, the most obvious pathological finding throughout the cerebellum was loss of purkinje cells, but the rarefaction of granular cell layers was observed only where loss of purkinje cells was very severe, and thinning of the molecular layer was seen only where the rarefaction of granular cell layers was moderate to severe. |
2008-05-21 |
2023-08-12 |
Not clear |
| Barbara Carletti, Ian Martin Williams, Ketty Leto, Kazunori Nakajima, Lorenzo Magrassi, Ferdinando Ross. Time constraints and positional cues in the developing cerebellum regulate Purkinje cell placement in the cortical architecture. Developmental biology. vol 317. issue 1. 2008-05-19. PMID:18384765. |
purkinje cells that follow the physiological route achieve the typical orientation and connectivity, but end displaced in the molecular layer if their arrival in the recipient cortex is delayed. |
2008-05-19 |
2023-08-12 |
Not clear |
| A Résibois, A Coppens, L Poncele. Naturally occurring parvovirus-associated feline hypogranular cerebellar hypoplasia-- A comparison to experimentally-induced lesions using immunohistology. Veterinary pathology. vol 44. issue 6. 2007-12-28. PMID:18039896. |
in type 1 lesions, the cortex was nearly agranular, with an extremely thin molecular layer; the purkinje cells were randomly placed and oriented, and their stunted main dendrite produced a thorn-covered atrophic dendritic tree; the basket cell axons ran randomly and had dysmorphic endings; and myelinated fibers were severely reduced in folia axes. |
2007-12-28 |
2023-08-12 |
Not clear |
| A Résibois, A Coppens, L Poncele. Naturally occurring parvovirus-associated feline hypogranular cerebellar hypoplasia-- A comparison to experimentally-induced lesions using immunohistology. Veterinary pathology. vol 44. issue 6. 2007-12-28. PMID:18039896. |
in type 2 lesions, the cortex was hypogranular; the purkinje cells were linearly organized, but their main dendrite extended too far in the molecular layer before giving up smooth, bent secondary dendrites; many basket cells were located along the cerebellar surface, and their axons ran at right angle to the surface; myelinated fibers were moderately reduced. |
2007-12-28 |
2023-08-12 |
Not clear |
| Erik J Olson, Arno Wünschmann, J P Dube. Sarcocystis sp.-associated meningoencephalitis in a bald eagle (Haliaeetus leucocephalus). Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. vol 19. issue 5. 2007-11-29. PMID:17823405. |
there was a marked segmental loss of granular cells and purkinje cells, as well as segmental atrophy of the molecular layer in the cerebellum. |
2007-11-29 |
2023-08-12 |
Not clear |
| Márcia C Carvalho, Jeferson L Franco, Heloisa Ghizoni, Karoline Kobus, Evelise M Nazari, João B T Rocha, Cristina W Nogueira, Alcir L Dafre, Yara M R Müller, Marcelo Farin. Effects of 2,3-dimercapto-1-propanesulfonic acid (DMPS) on methylmercury-induced locomotor deficits and cerebellar toxicity in mice. Toxicology. vol 239. issue 3. 2007-11-09. PMID:17703864. |
a marked mercury deposition in the cerebellar cortex was observed in mehg-exposed animals (granular layer>purkinje cells>molecular layer) and dmps treatment displayed a significant ameliorative effect toward these phenomena. |
2007-11-09 |
2023-08-12 |
mouse |
| Brandon M Stell, Philippe Rostaing, Antoine Triller, Alain Mart. Activation of presynaptic GABA(A) receptors induces glutamate release from parallel fiber synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 34. 2007-09-11. PMID:17715339. |
the parallel fibers relay information coming into the cerebellar cortex from the mossy fibers, and they form synapses with molecular layer interneurons (mlis) and purkinje cells. |
2007-09-11 |
2023-08-12 |
Not clear |
| Yoshiko Takagishi, Kouichi Hashimoto, Tetsuro Kayahara, Masahiko Watanabe, Hiroyuki Otsuka, Akira Mizoguchi, Masanobu Kano, Yoshiharu Murat. Diminished climbing fiber innervation of Purkinje cells in the cerebellum of myosin Va mutant mice and rats. Developmental neurobiology. vol 67. issue 7. 2007-07-31. PMID:17506494. |
here, we explored the role of myosin va in the formation of synaptic circuitry by examining climbing fiber (cf) innervation of purkinje cells (pcs) in the cerebella of dilute-neurological (d-n) mice and dilute-opisthotonus (dop) rats that have mutations in dilute-encoded myosin va. anterograde labeling of cfs with biotinylated dextran amine (bda) revealed that they arborized poorly and that their tips extended only half way through the thickness of the molecular layer (ml) in adult d-n mice. |
2007-07-31 |
2023-08-12 |
mouse |
| S K Tripathi, S K Pande. The effect of aluminium phosphide on the human brain: a histological study. Medicine, science, and the law. vol 47. issue 2. 2007-06-26. PMID:17520959. |
findings in the cerebellar cortex included degenerated neurons, the infiltration of round cells into the molecular layer and the disappearance of the processes of purkinje cells. |
2007-06-26 |
2023-08-12 |
human |
| Akihiko S Kato, Wei Zhou, Aaron D Milstein, Mike D Knierman, Edward R Siuda, Joe E Dotzlaf, Hong Yu, John E Hale, Eric S Nisenbaum, Roger A Nicoll, David S Bred. New transmembrane AMPA receptor regulatory protein isoform, gamma-7, differentially regulates AMPA receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 18. 2007-06-06. PMID:17475805. |
western blotting reveals high levels of gamma-5 and gamma-7 in the cerebellum, where gamma-7 is enriched in purkinje neurons in the molecular layer and glomerular synapses in the granule cell layer. |
2007-06-06 |
2023-08-12 |
mouse |
| Emma Gheorghe, S Vameşu, V Tomuta, Mihaela Hîncu, T Mehedinţi, G Nicol. Cerebellar atrophy--a comparative microscopic study. Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. vol 47. issue 4. 2007-06-05. PMID:17392980. |
in order to analyze the histological modifications we determined the following parameters: thickness of the cerebellar cortex--is a derived feature appropriate for elongated or thin structures, area fraction of the molecular layer in the cerebellar cortex, number of purkinje neurons per microscopic field and area fraction of the blood vessels per microscopic field. |
2007-06-05 |
2023-08-12 |
Not clear |
| Yukun Yuan, William D Atchiso. Methylmercury-induced increase of intracellular Ca2+ increases spontaneous synaptic current frequency in rat cerebellar slices. Molecular pharmacology. vol 71. issue 4. 2007-06-04. PMID:17244699. |
simultaneous confocal imaging and whole-cell recording revealed that time to onset of mehg-induced increase in fluorescence in the molecular layer correlated with that of increased sepsc and sipsc frequency in purkinje cells. |
2007-06-04 |
2023-08-12 |
rat |
| Takenori Kotani, Nobuhiro Morone, Shigeki Yuasa, Shigeyuki Nada, Masato Okad. Constitutive activation of neuronal Src causes aberrant dendritic morphogenesis in mouse cerebellar Purkinje cells. Neuroscience research. vol 57. issue 2. 2007-04-17. PMID:17137665. |
the aberrant purkinje cells in n-src transgenic mice retained multiple dendritic shafts extending in non-polarized directions and were located heterotopically in the molecular layer. |
2007-04-17 |
2023-08-12 |
mouse |
| Zarah Pernber, Katrin Richter, Jan-Eric Mansson, Hakan Nygre. Sulfatide with different fatty acids has unique distributions in cerebellum as imaged by time-of-flight secondary ion mass spectrometry (TOF-SIMS). Biochimica et biophysica acta. vol 1771. issue 2. 2007-04-03. PMID:17257892. |
the molecular layer and purkinje cells were devoid of sulfatide signals. |
2007-04-03 |
2023-08-12 |
rat |
| Zarah Pernber, Katrin Richter, Jan-Eric Mansson, Hakan Nygre. Sulfatide with different fatty acids has unique distributions in cerebellum as imaged by time-of-flight secondary ion mass spectrometry (TOF-SIMS). Biochimica et biophysica acta. vol 1771. issue 2. 2007-04-03. PMID:17257892. |
immunofluorescence showed the highest intensity in the white matter, lower intensity in the granular layer and absence of fluorescence in the molecular layer and purkinje cells. |
2007-04-03 |
2023-08-12 |
rat |
| Osamu Yokota, Kuniaki Tsuchiya, Seishi Terada, Kenichi Oshima, Hideki Ishizu, Masaaki Matsushita, Shigetoshi Kuroda, Haruhiko Akiyam. Frequency and clinicopathological characteristics of alcoholic cerebellar degeneration in Japan: a cross-sectional study of 1,509 postmortems. Acta neuropathologica. vol 112. issue 1. 2007-03-29. PMID:16622656. |
in acd cases, loss of purkinje cells, narrowing of the width of the molecular layer, and tissue rarefaction in the granular layer were observed in the anterior and superior portions of the vermis of the cerebellum. |
2007-03-29 |
2023-08-12 |
human |
| Jonathan Mapelli, Egidio D'Angel. The spatial organization of long-term synaptic plasticity at the input stage of cerebellum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 6. 2007-03-06. PMID:17287503. |
by this mechanism, ltp and ltd could regulate the geometry and contrast of network computations, preprocessing the mossy fiber input to be conveyed to purkinje cells and molecular layer interneurons. |
2007-03-06 |
2023-08-12 |
Not clear |