| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Fujimura, F Usuk. Low in situ expression of antioxidative enzymes in rat cerebellar granular cells susceptible to methylmercury. Archives of toxicology. vol 88. issue 1. 2014-10-28. PMID:23832298. |
we observed that expression of manganese-superoxide dismutase (mn-sod), glutathione peroxidase 1 (gpx1), and thioredoxin reductase 1 (trxr1) was significantly higher in purkinje cells and molecular layer neurons than in cgcs. |
2014-10-28 |
2023-08-12 |
rat |
| M Fujimura, F Usuk. Low in situ expression of antioxidative enzymes in rat cerebellar granular cells susceptible to methylmercury. Archives of toxicology. vol 88. issue 1. 2014-10-28. PMID:23832298. |
immunohistochemistry showed increased expression of mn-sod, gpx1, and trxr1 in purkinje cells and molecular layer neurons, which was coincident with the mrna expression patterns. |
2014-10-28 |
2023-08-12 |
rat |
| Jimmie M Gmaz, Bruce E McKa. Toluene decreases Purkinje cell output by enhancing inhibitory synaptic transmission in the cerebellar cortex. Neuroscience letters. vol 560. 2014-09-08. PMID:24345417. |
furthermore, toluene dose-dependently enhanced inhibitory synaptic transmission onto purkinje cells, increasing the amplitude and frequency of inhibitory postsynaptic currents; no change in the frequency of action potentials from molecular layer interneurons was noted. |
2014-09-08 |
2023-08-12 |
rat |
| Chang-Hyun Song, Doug Bernhard, Ellen J Hess, H A Jinna. Subtle microstructural changes of the cerebellum in a knock-in mouse model of DYT1 dystonia. Neurobiology of disease. vol 62. 2014-09-03. PMID:24121114. |
there also was a higher frequency of heterotopic purkinje cells displaced into the molecular layer. |
2014-09-03 |
2023-08-12 |
mouse |
| Daria Camera, Natasha A Boase, Sharad Kumar, David V Pow, Philip Poronni. Subtle gait abnormalities in Nedd4 heterozygous mice. Behavioural brain research. vol 260. 2014-09-02. PMID:24280120. |
there appeared to be a redistribution of glur1 into larger puncta in the molecular layer and in the membrane of the soma of the purkinje neurons. |
2014-09-02 |
2023-08-12 |
mouse |
| M Hirono, S Nagao, K Obat. Developmental α₂-adrenergic regulation of noradrenergic synaptic facilitation at cerebellar GABAergic synapses. Neuroscience. vol 256. 2014-08-27. PMID:24157933. |
previous studies have demonstrated that α₂-adrenoceptor (α₂-ar) activation eliminates spontaneous action potentials of interneurons in the cerebellar molecular layer (mlis) and subsequently reduces the frequency of spontaneous inhibitory postsynaptic currents (sipscs) in purkinje cells (pcs) after the second postnatal week. |
2014-08-27 |
2023-08-12 |
Not clear |
| Sajedeh Eftekhari, Christopher A Salvatore, Renee C Gaspar, Rhonda Roberts, Stacey O'Malley, Zhizhen Zeng, Lars Edvinsso. Localization of CGRP receptor components, CGRP, and receptor binding sites in human and rhesus cerebellar cortex. Cerebellum (London, England). vol 12. issue 6. 2014-05-30. PMID:23917876. |
immunofluorescence revealed expression of cgrp, clr, and ramp1 in the purkinje cells and in cells in the molecular layer. |
2014-05-30 |
2023-08-12 |
human |
| Daniela Gandolfi, Paolo Pozzi, Marialuisa Tognolina, Giuseppe Chirico, Jonathan Mapelli, Egidio D'Angel. The spatiotemporal organization of cerebellar network activity resolved by two-photon imaging of multiple single neurons. Frontiers in cellular neuroscience. vol 8. 2014-04-30. PMID:24782707. |
with slm-2pm, calcium signals could be recorded from different network elements in acute cerebellar slices including granule cells (grcs), purkinje cells (pcs) and molecular layer interneurons. |
2014-04-30 |
2023-08-13 |
Not clear |
| Ruth M Empson, Helena Huang, Raghavendra Y Nagaraja, Chris J Roome, Thomas Knöpfe. Enhanced synaptic inhibition in the cerebellar cortex of the ataxic PMCA2(-/-) knockout mouse. Cerebellum (London, England). vol 12. issue 5. 2014-04-10. PMID:23568408. |
purkinje neurons from pmca2(-/-) mice exhibited an increased frequency and amplitude of spontaneous inhibitory post-synaptic currents that was accompanied by an enhanced spontaneous firing frequency of molecular layer interneurons (both basket cells and stellate cells). |
2014-04-10 |
2023-08-12 |
mouse |
| Pontus Geborek, Anton Spanne, Fredrik Bengtsson, Henrik Jörntel. Cerebellar cortical neuron responses evoked from the spinal border cell tract. Frontiers in neural circuits. vol 7. 2014-04-08. PMID:24115921. |
the aim of the present study is to achieve activation of a single component of the spinocerebellar systems and to explore to what extent it can influence the spike output of granule cells, golgi cells, molecular layer (ml) interneurons (stellate and basket cells) and purkinje cells (pcs). |
2014-04-08 |
2023-08-12 |
Not clear |
| Kotaro Kawanishi, Mitsuya Morita, Keiichi Nakahara, Syuichi Tetsuka, Tom Kouki, Kaoru Tominaga, Hitoshi Endo, Takashi Yashiro, Keiko Tanaka, Imaharu Nakan. [Paraneoplastic cerebellar degeneration with bladder cancer confirmed the existence of an anti-neural antibody: a case report]. Brain and nerve = Shinkei kenkyu no shinpo. vol 65. issue 11. 2014-03-06. PMID:24200618. |
immunohistochemical staining of mouse cerebellum using the patient's serum revealed coarse granular staining in the cytoplasm of purkinje cells and diffuse staining in the neuropil of the molecular layer, suggesting the presence of an unknown antibody. |
2014-03-06 |
2023-08-12 |
mouse |
| Reinoud Maex, Volker Steube. An integrator circuit in cerebellar cortex. The European journal of neuroscience. vol 38. issue 6. 2014-03-03. PMID:23731348. |
in this model, comprising purkinje cells, molecular layer interneurons and parallel fibres, purkinje cells were able to generate responses lasting more than 10 s, to which both neuronal and network mechanisms contributed. |
2014-03-03 |
2023-08-12 |
Not clear |
| Joaquín Martí, María C Santa-Cruz, Roger Serra, Oliver Valero, Vanessa Molina, José P Hervás, Sandra Villega. Principal component and cluster analysis of morphological variables reveals multiple discrete sub-phenotypes in weaver mouse mutants. Cerebellum (London, England). vol 12. issue 3. 2013-12-04. PMID:23179325. |
the quantified parameters were length of the cerebellar cortex, area of the external granular layer, area of the molecular layer, number of the external granular layer cells (egl), and number of purkinje cells (pcs). |
2013-12-04 |
2023-08-12 |
mouse |
| Junko Sato, Satoshi Sasaki, Naoaki Yamada, Minoru Tsuchitan. Early morphological changes of hereditary cerebellar cortical abiotrophy in rabbits. The Journal of veterinary medical science. vol 75. issue 4. 2013-12-02. PMID:23182865. |
the affected rabbit showed apoptotic granular cells before and after migration completion, degeneration (swelling) of parallel fiber terminals, abnormal junction (invaginated junction) of the parallel fiber-purkinje cell synapses and irregular orientation of the purkinje dendritic arbor in the molecular layer. |
2013-12-02 |
2023-08-12 |
rabbit |
| Maren C Kiessling, Andreas Büttner, Camilla Butti, Jens Müller-Starck, Stefan Milz, Patrick R Hof, Hans-Georg Frank, Christoph Schmit. Intact numbers of cerebellar purkinje and granule cells in sudden infant death syndrome: a stereologic analysis and critical review of neuropathologic evidence. Journal of neuropathology and experimental neurology. vol 72. issue 9. 2013-10-21. PMID:23965745. |
neither the volumes of the cerebellar external granule cell layer, molecular layer, internal granule cell layer (including the purkinje cell layer), and white matter nor the total numbers of purkinje cells, granule cells in the internal granule cell layer, and the number of granule cells per purkinje cell showed statistically significant differences between the sids cases and the controls. |
2013-10-21 |
2023-08-12 |
Not clear |
| Y Zhao, J Xiao, S Gong, J A Clara, M S Ledou. Neural expression of the transcription factor THAP1 during development in rat. Neuroscience. vol 231. 2013-07-25. PMID:23219941. |
in contrast, it was more diffusely distributed throughout the dendritic arbor of adult purkinje cells producing a moderate diffuse staining pattern in the molecular layer. |
2013-07-25 |
2023-08-12 |
rat |
| J Sato, S Sasaki, N Yamada, M Tsuchitan. Hereditary cerebellar degenerative disease (cerebellar cortical abiotrophy) in rabbits. Veterinary pathology. vol 49. issue 4. 2013-07-08. PMID:21646443. |
electron microscopy confirmed the thinning of the molecular layer seen by light microscopy and also showed a reduced number of parallel fibers, which indicate granular cells axons, and a reduced number of synaptic junctions between purkinje and granular cells. |
2013-07-08 |
2023-08-12 |
Not clear |
| Azubike P Ebokaiwe, Isaac A Adedara, Olatunde Owoeye, Ebenezer O Faromb. Neurotoxicity of Nigerian bonny light crude oil in rats. Drug and chemical toxicology. vol 36. issue 2. 2013-06-28. PMID:23020769. |
although the purkinje layer and maximum width of purkinje cells were not affected, blco treatment significantly decreased molecular layer, granular layer, and density of purkinje cells of the cerebellum. |
2013-06-28 |
2023-08-12 |
rat |
| Dan-Anders Jirenhed, Fredrik Bengtsson, Henrik Jörntel. Parallel fiber and climbing fiber responses in rat cerebellar cortical neurons in vivo. Frontiers in systems neuroscience. vol 7. 2013-06-05. PMID:23730272. |
we describe the spike responses of molecular layer interneurons (mli) in the hemispheric crus1/crus2 region and compare them with those of purkinje cells (pcs) and golgi cells (gcs), both with respect to spontaneous activity and responses evoked by direct electrical stimulation of parallel fibers (pfs) and climbing fibers (cfs). |
2013-06-05 |
2023-08-12 |
rat |
| Paul J Mathews, Ka Hung Lee, Zechun Peng, Carolyn R Houser, Thomas S Oti. Effects of climbing fiber driven inhibition on Purkinje neuron spiking. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 50. 2013-02-27. PMID:23238715. |
as expected, optical stimulation of chr2-expressing cfs generates complex spike responses in individual purkinje neurons (pns); in addition we found that such stimulation recruits a network of inhibitory interneurons in the molecular layer. |
2013-02-27 |
2023-08-12 |
rat |