| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M J Urbanski, F E Kovacs, B Szab. Endocannabinoid-mediated synaptically evoked suppression of GABAergic transmission in the cerebellar cortex. Neuroscience. vol 169. issue 3. 2010-12-16. PMID:20553815. |
finally, the gabaergic synaptic transmission between molecular layer interneurons and purkinje cells was directly studied on simultaneously patch-clamped neuron pairs. |
2010-12-16 |
2023-08-12 |
mouse |
| Federica Briatore, Annarita Patrizi, Laura Viltono, Marco Sassoè-Pognetto, Peer Wulf. Quantitative organization of GABAergic synapses in the molecular layer of the mouse cerebellar cortex. PloS one. vol 5. issue 8. 2010-11-04. PMID:20711348. |
in the cerebellar cortex, interneurons of the molecular layer (stellate and basket cells) provide gabaergic input to purkinje cells, as well as to each other and possibly to other interneurons. |
2010-11-04 |
2023-08-12 |
mouse |
| R A Marusak, J S Guy, T A Abdul-Aziz, M A West, O J Fletcher, J M Day, L Zsak, H John Barne. Parvovirus-associated cerebellar hypoplasia and hydrocephalus in day old broiler chickens. Avian diseases. vol 54. issue 1. 2010-05-11. PMID:20408417. |
affected cerebellums had focal areas along the base of folia where the internal granular cell layer had been lost, and purkinje cells were disorganized and located within the molecular layer. |
2010-05-11 |
2023-08-12 |
chicken |
| Michael C Stankewich, Babette Gwynn, Thomas Ardito, Lan Ji, Jung Kim, Raymond F Robledo, Samuel E Lux, Luanne L Peters, Jon S Morro. Targeted deletion of betaIII spectrin impairs synaptogenesis and generates ataxic and seizure phenotypes. Proceedings of the National Academy of Sciences of the United States of America. vol 107. issue 13. 2010-04-28. PMID:20231455. |
the cerebellum displays increased dark purkinje cells (pc), a thin molecular layer, fewer synapses, a loss of dendritic spines, and a 2-fold expansion of the pc dendrite diameter. |
2010-04-28 |
2023-08-12 |
mouse |
| G Le Dréau, A Nicot, M Bénard, H Thibout, D Vaudry, C Martinerie, M Lauren. NOV/CCN3 promotes maturation of cerebellar granule neuron precursors. Molecular and cellular neurosciences. vol 43. issue 1. 2010-04-22. PMID:19286457. |
nov transcripts are specifically produced by purkinje neurons and nov protein localises extracellularly in the molecular layer and the inner part of the external granule layer, at a key position to control gnp proliferation and migration. |
2010-04-22 |
2023-08-12 |
rat |
| Andrew J Sachs, Samuel A David, Neena B Haider, Arne M Nystue. Patterned neuroprotection in the Inpp4a(wbl) mutant mouse cerebellum correlates with the expression of Eaat4. PloS one. vol 4. issue 12. 2010-03-17. PMID:20011524. |
loss occurs early in postnatal development; however, prior to the appearance of climbing fibers in the developing molecular layer, the mutant has a normal complement of purkinje cells and they are properly positioned. |
2010-03-17 |
2023-08-12 |
mouse |
| Mia Kim, Changjong Moon, Heechul Kim, Min Kyoung Shin, Do Sik Min, Taekyun Shi. Developmental levels of phospholipase D isozymes in the brain of developing rats. Acta histochemica. vol 112. issue 1. 2010-03-04. PMID:19010519. |
in the hindbrain, pld was found in some purkinje cells and some cells of the molecular layer, as well as glial cells, consistent with the results obtained from western blot analysis. |
2010-03-04 |
2023-08-12 |
rat |
| P Mouser, M Lévy, J E Sojka, J A Ramos-Var. Cerebellar abiotrophy in an alpaca (Lama pacos). Veterinary pathology. vol 46. issue 6. 2010-02-05. PMID:19605911. |
histologic lesions, confined to the cerebellar vermis, included marked absence of purkinje cells, decreased granule cells, narrowing of the molecular layer, and thinning of white matter tracts consistent with abiotrophy. |
2010-02-05 |
2023-08-12 |
Not clear |
| Mika Tanaka, Kazuhiko Yamaguchi, Tetsuya Tatsukawa, Chieko Nishioka, Hiroshi Nishiyama, Martin Theis, Klaus Willecke, Shigeyoshi Itohar. Lack of Connexin43-mediated bergmann glial gap junctional coupling does not affect cerebellar long-term depression, motor coordination, or eyeblink conditioning. Frontiers in behavioral neuroscience. vol 2. 2009-12-16. PMID:18958191. |
in the mature cerebellar molecular layer, bergmann glial processes are closely associated with purkinje cells, enclosing purkinje cell dendritic synapses with a glial sheath. |
2009-12-16 |
2023-08-12 |
mouse |
| M Kuwamura, F Murai, S Nishioka, M Aoki, F Ohashi, J Yamate, T Kotani, B A Summer. Late onset cerebellar cortical degeneration in a koala. Australian veterinary journal. vol 87. issue 8. 2009-11-12. PMID:19673852. |
histopathologically, a severe loss of purkinje and granule cells was evident in the cerebellum, while the molecular layer was more cellular than normal with cells resembling small neurons, which were positively stained with parvalbumin immunohistochemistry. |
2009-11-12 |
2023-08-12 |
Not clear |
| Takashi Torashima, Akira Iizuka, Hajime Horiuchi, Kazuhiro Mitsumura, Miwako Yamasaki, Chiho Koyama, Kiyohiko Takayama, Masae Iino, Masahiko Watanabe, Hirozaku Hira. Rescue of abnormal phenotypes in delta2 glutamate receptor-deficient mice by the extracellular N-terminal and intracellular C-terminal domains of the delta2 glutamate receptor. The European journal of neuroscience. vol 30. issue 3. 2009-10-27. PMID:19614753. |
notably, the expression of ntd-tm4-ctd in glurdelta2-deficient purkinje cells restored abrogated ltd, and aberrant cf territory in the molecular layer. |
2009-10-27 |
2023-08-12 |
mouse |
| Masayuki Shintaku, Daita Kaned. Chromosome 16q22.1-linked autosomal dominant cerebellar ataxia: an autopsy case report with some new observations on cerebellar pathology. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 29. issue 3. 2009-10-19. PMID:18627481. |
main neuropathological findings included moderate loss of purkinje cells, variegated degenerative features of the remaining purkinje cells, finely fibrillary material surrounding the perikarya of purkinje cells, and ubiquitin-immunoreactive small dots in the molecular layer and cerebellar white matter. |
2009-10-19 |
2023-08-12 |
Not clear |
| Federico F Trigo, George Papageorgiou, John E T Corrie, David Ogde. Laser photolysis of DPNI-GABA, a tool for investigating the properties and distribution of GABA receptors and for silencing neurons in situ. Journal of neuroscience methods. vol 181. issue 2. 2009-09-16. PMID:19422852. |
finally, at low dpni-gaba concentration, photorelease restricted to the area of the soma suppressed spiking in single purkinje neurons or molecular layer interneurons for periods controlled by the flash intensity and duration. |
2009-09-16 |
2023-08-12 |
Not clear |
| Peer Wulff, Martijn Schonewille, Massimiliano Renzi, Laura Viltono, Marco Sassoè-Pognetto, Aleksandra Badura, Zhenyu Gao, Freek E Hoebeek, Stijn van Dorp, William Wisden, Mark Farrant, Chris I De Zeeu. Synaptic inhibition of Purkinje cells mediates consolidation of vestibulo-cerebellar motor learning. Nature neuroscience. vol 12. issue 8. 2009-09-09. PMID:19578381. |
using a mouse line (pc-deltagamma2) in which gaba(a) receptor-mediated synaptic inhibition is selectively removed from purkinje cells, we examined how feedforward inhibition from molecular layer interneurons regulates adaptation of the vestibulo-ocular reflex. |
2009-09-09 |
2023-08-12 |
mouse |
| Luz Delgado, Oliver Schmachtenber. Immunohistochemical localization of GABA, GAD65, and the receptor subunits GABAAalpha1 and GABAB1 in the zebrafish cerebellum. Cerebellum (London, England). vol 7. issue 3. 2009-05-15. PMID:18633686. |
gaba and gad65 presented a similar expression pattern that comprised the molecular layer, purkinje cells and groups of presumed golgi cells in the granular layer, both in the cerebellar corpus and valve. |
2009-05-15 |
2023-08-12 |
zebrafish |
| Luz Delgado, Oliver Schmachtenber. Immunohistochemical localization of GABA, GAD65, and the receptor subunits GABAAalpha1 and GABAB1 in the zebrafish cerebellum. Cerebellum (London, England). vol 7. issue 3. 2009-05-15. PMID:18633686. |
gaba(a) receptor subunits are principally found on fine radial fibers in the molecular layer, while gaba(b) receptor subunits localized prominently to the cell bodies of purkinje cells in the ganglionic layer, and to their dendrites that span the molecular layer. |
2009-05-15 |
2023-08-12 |
zebrafish |
| I B Krasno. [Electron microscopy analysis of the structural elements of the vestibular input to nodulus Purkinje's cells in rats exposed to a 9-day space flight]. Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine. vol 42. issue 4. 2009-03-24. PMID:19140468. |
electron microscopy was used to study structural elements of the vestibular afferent input to the cerebellar nodulus purkinje's cells--terminals of mossy fibers and granular cells in the granular layer and parallel fibers and purkinje's cell dendrites in the molecular layer in rats decapitated in 2-3 hours and 9 days after the 9-day space flight aboard nasa shuttle columbia (sts 40, sls-1 mission). |
2009-03-24 |
2023-08-12 |
rat |
| Takahiko Umahara, Toshiki Uchihara, Ayako Nakamura, Toshihiko Iwamot. Isoform-dependent immunolocalization of 14-3-3 proteins in developing rat cerebellum. Brain research. vol 1253. 2009-03-17. PMID:19070608. |
in contrast, epsilon isoform-like ir was initially identified in processes of radial and bergmann glia at p2 prior to its appearance in the molecular layer at p7 with subsequent intensification also in purkinje cells after p14. |
2009-03-17 |
2023-08-12 |
rat |
| Yoshiki Niimi, Yasushi Iwasaki, Toshitaka Umemura, Fumiaki Tanaka, Mari Yoshida, Yoshio Hashizume, Tetsuyuki Kitamoto, Mikio Hirayama, Gen Sobu. MM2-cortical-type sporadic Creutzfeldt-Jakob disease with early stage cerebral cortical pathology presenting with a rapidly progressive clinical course. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 28. issue 6. 2009-01-28. PMID:18410280. |
in the cerebellar cortex, slight depletion of purkinje neurons was evident without spongiform change in the molecular layer or apparent neuron loss in the granule cell layer. |
2009-01-28 |
2023-08-12 |
Not clear |
| Manuel Mameli, Paolo Botta, Paula A Zamudio, Stefano Zucca, C Fernando Valenzuel. Ethanol decreases Purkinje neuron excitability by increasing GABA release in rat cerebellar slices. The Journal of pharmacology and experimental therapeutics. vol 327. issue 3. 2009-01-05. PMID:18755936. |
cerebellar purkinje neurons (pns) receive inhibitory gabaergic input from stellate and basket cells, which are located in the outer and inner portions of the molecular layer, respectively. |
2009-01-05 |
2023-08-12 |
rat |