| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Emmanuel P Gilissen, Ludmilla Staneva-Dobrovsk. Distinct types of lipofuscin pigment in the hippocampus and cerebellum of aged cheirogaleid primates. Anatomical record (Hoboken, N.J. : 2007). vol 296. issue 12. 2014-07-23. PMID:24124014. |
this suggests differences in cellular metabolism and/or in organelles involved in lipofuscin production in cerebellar purkinje cells and in hippocampal dentate gyrus neurons. |
2014-07-23 |
2023-08-12 |
mouse |
| J A Kennard, K L Brown, D S Woodruff-Pa. Aging in the cerebellum and hippocampus and associated behaviors over the adult life span of CB6F1 mice. Neuroscience. vol 247. 2014-03-18. PMID:23764510. |
to assess the effects of age on the brain, hippocampus volume was calculated and unbiased stereology was used to estimate the number of purkinje neurons in the cerebellar cortex. |
2014-03-18 |
2023-08-12 |
mouse |
| J A Kennard, K L Brown, D S Woodruff-Pa. Aging in the cerebellum and hippocampus and associated behaviors over the adult life span of CB6F1 mice. Neuroscience. vol 247. 2014-03-18. PMID:23764510. |
a significant, age-related loss of purkinje neurons was found-beginning at 12 months of age-and hippocampus volume remained stable over the adult life span. |
2014-03-18 |
2023-08-12 |
mouse |
| Delphine Rocas, Eudeline Alix, Jessica Michel, Marie-Pierre Cordier, Audrey Labalme, Hélène Guilbert, Marianne Till, Caroline Schluth-Bolard, Pascale de Haas, Jérôme Massardier, Vincent des Portes, Patrick Edery, Renaud Touraine, Laurent Guibaud, Alexandre Vasiljevic, Damien Sanlavill. Neuropathological features in a female fetus with OPHN1 deletion and cerebellar hypoplasia. European journal of medical genetics. vol 56. issue 5. 2014-01-02. PMID:23416624. |
ophn1 is involved in x-linked mental retardation (xlmr) with cerebellar hypoplasia and encodes a rho-gtpase-activating protein called oligophrenin-1, which is produced throughout the developing mouse brain and in the hippocampus and purkinje cells of the cerebellum in adult mice. |
2014-01-02 |
2023-08-12 |
mouse |
| Franz Hofmann, Jörg W Wegene. cGMP-dependent protein kinases (cGK). Methods in molecular biology (Clifton, N.J.). vol 1020. 2013-12-30. PMID:23709024. |
the cgki isozymes are prominent in all types of smooth muscle, platelets, and specific neuronal areas such as cerebellar purkinje cells, hippocampal neurons, and the lateral amygdala. |
2013-12-30 |
2023-08-12 |
Not clear |
| Nicolas Gutierrez-Castellanos, Beerend H J Winkelman, Leonardo Tolosa-Rodriguez, Benjamin Devenney, Roger H Reeves, Chris I De Zeeu. Size does not always matter: Ts65Dn Down syndrome mice show cerebellum-dependent motor learning deficits that cannot be rescued by postnatal SAG treatment. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 39. 2013-11-25. PMID:24068809. |
together with the previous observation that the synaptic properties of purkinje cells are also unchanged by sag treatment, this lack of improvement in a region-specific behavioral assay supports the possibility that a direct effect of shh pathway stimulation on the hippocampus might explain the benefits of this potential approach to the improvement of cognition in ds. |
2013-11-25 |
2023-08-12 |
mouse |
| Sahabudeen Sheik Mohideen, Sahoko Ichihara, Kaviarasan Subramanian, Zhenlie Huang, Hisao Naito, Junzoh Kitoh, Gaku Ichihar. Effects of exposure to 1-bromopropane on astrocytes and oligodendrocytes in rat brain. Journal of occupational health. vol 55. issue 1. 2013-09-30. PMID:23183024. |
human cases of 1-bromopropane (1-bp) toxicity showed ataxic gait and cognitive dysfunction, whereas rat studies showed pyknotic shrinkage in cerebellar purkinje cells and electrophysiological changes in the hippocampus. |
2013-09-30 |
2023-08-12 |
human |
| Verena Pfeiffer, Rudolf Götz, Chaomei Xiang, Guadelupe Camarero, Attila Braun, Yina Zhang, Robert Blum, Helmut Heinsen, Bernhard Nieswandt, Ulf R Rap. Ablation of BRaf impairs neuronal differentiation in the postnatal hippocampus and cerebellum. PloS one. vol 8. issue 3. 2013-09-06. PMID:23505473. |
in addition we observed reduced numbers and misplaced ectopic purkinje cells that showed an altered structure of their dendritic arborizations in the hippocampus, while the overall cornus ammonis architecture appeared to be unchanged. |
2013-09-06 |
2023-08-12 |
mouse |
| Y Zhao, J Xiao, S Gong, J A Clara, M S Ledou. Neural expression of the transcription factor THAP1 during development in rat. Neuroscience. vol 231. 2013-07-25. PMID:23219941. |
in addition to purkinje cells in the cerebellum, thap1-ir was also localized to pyramidal neurons in the cerebral cortex, relay neurons in the thalamus, medium spiny and cholinergic neurons in the striatum, dopaminergic neurons in the substantia nigra, and pyramidal and interneurons in the hippocampus. |
2013-07-25 |
2023-08-12 |
rat |
| Levent Kaya, Barbara Meissner, Maria Christine Riedl, Martin Muik, Christoph Schwarzer, Francesco Ferraguti, Bettina Sarg, Herbert Lindner, Rüdiger Schweigreiter, Hans-Günther Knaus, Christoph Romanin, Christine E Bandtlo. Direct association of the reticulon protein RTN1A with the ryanodine receptor 2 in neurons. Biochimica et biophysica acta. vol 1833. issue 6. 2013-07-11. PMID:23454728. |
rtn1a displays high preference for ryr2 binding in vitro and in vivo and both proteins colocalize in hippocampal neurons and purkinje cells. |
2013-07-11 |
2023-08-12 |
Not clear |
| H Y Liu, Y N Wang, J Y Ge, N Li, X-L Cui, Z-H Li. Localisation and role of activin receptor-interacting protein 1 in mouse brain. Journal of neuroendocrinology. vol 25. issue 1. 2013-06-05. PMID:22849377. |
in the present study, we confirmed the existence of mrna and protein of arip1 in the mouse brain, and found that arip1 was mainly localised at the hippocampus and hypothalamus in the cerebrum, granular layers in the cerebellum (especially in purkinje cells of the cerebellum) and choroid epithelial cells by immunohistochemical staining. |
2013-06-05 |
2023-08-12 |
mouse |
| Diana Jurk, Chunfang Wang, Satomi Miwa, Mandy Maddick, Viktor Korolchuk, Avgi Tsolou, Efstathios S Gonos, Christopher Thrasivoulou, M Jill Saffrey, Kerry Cameron, Thomas von Zglinick. Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response. Aging cell. vol 11. issue 6. 2013-04-18. PMID:22882466. |
about 40-80% of purkinje neurons and 20-40% of cortical, hippocampal and peripheral neurons in the myenteric plexus from old c57bl/6 mice showed severe dna damage, activated p38mapkinase, high ros production and oxidative damage, interleukin il-6 production, heterochromatinization and senescence-associated β-galactosidase activity. |
2013-04-18 |
2023-08-12 |
mouse |
| B Ya Ryzhavskii, O V Zadvornay. Effect of gonadectomy on activity of neuronal 3β-hydroxysteroid dehydrogenase in some brain structures. Bulletin of experimental biology and medicine. vol 153. issue 5. 2013-03-12. PMID:23113285. |
the positive reaction was detected in hippocampal neurons, ganglionic layer cells of the cerebellar cortex (purkinje cells), and solitary neocortical neurons of male and female rats. |
2013-03-12 |
2023-08-12 |
rat |
| B Ya Ryzhavskii, O V Zadvornay. Effect of gonadectomy on activity of neuronal 3β-hydroxysteroid dehydrogenase in some brain structures. Bulletin of experimental biology and medicine. vol 153. issue 5. 2013-03-12. PMID:23113285. |
gonadectomy significantly increased enzyme activity in neocortical (layer v) and hippocampal neurons and had no effect on the intensity of the reaction in purkinje cells. |
2013-03-12 |
2023-08-12 |
rat |
| Jia Lu, Kian Chye Ng, Geoffrey Ling, Jian Wu, David Jia Fei Poon, Enci Mary Kan, Mui Hong Tan, Ya Jun Wu, Ping Li, Shabbir Moochhala, Eric Yap, Lionel Kim Hock Lee, Melissa Teo, Ing Berne Yeh, Darvi Michell Bufete Sergio, Frederic Chua, Srinivasan Dinesh Kumar, Eng-Ang Lin. Effect of blast exposure on the brain structure and cognition in Macaca fascicularis. Journal of neurotrauma. vol 29. issue 7. 2013-02-05. PMID:21639720. |
mri and histopathology revealed ultrastructural changes in the brain, notably in the purkinje neurons in the cerebellum and pyramidal neurons in the hippocampus, which were most vulnerable to the blast. |
2013-02-05 |
2023-08-12 |
monkey |
| Eriko Fujita, Yuko Tanabe, Beat A Imhof, Mariko Y Momoi, Takashi Momo. A complex of synaptic adhesion molecule CADM1, a molecule related to autism spectrum disorder, with MUPP1 in the cerebellum. Journal of neurochemistry. vol 123. issue 5. 2013-01-10. PMID:22994563. |
cadm1 colocalized with mupp1 and gabbr2 on the dendrites of purkinje cells in the molecular layers of the developing cerebellum and on the dendrites of hippocampal neurons cultured in vitro. |
2013-01-10 |
2023-08-12 |
mouse |
| Christophe Stenger, Anthony Pinçon, Marine Hanse, Laurent Royer, Audrey Comte, Violette Koziel, Jean-Luc Olivier, Thierry Pillot, Frances T Ye. Brain region-specific immunolocalization of the lipolysis-stimulated lipoprotein receptor (LSR) and altered cholesterol distribution in aged LSR+/- mice. Journal of neurochemistry. vol 123. issue 4. 2012-12-21. PMID:22909011. |
using immunofluorescence, we describe the region-specific expression of the lipolysis-stimulated lipoprotein receptor (lsr), in the mouse hippocampus, cerebellum purkinje cells, the ependymal cell interface between brain parenchyma and cerebrospinal fluid, and the choroid plexus. |
2012-12-21 |
2023-08-12 |
mouse |
| Melanie Thelen, Markus Damme, Markus Daμμe, Michaela Schweizer, Christian Hagel, Andrew M S Wong, Jonathan D Cooper, Thomas Braulke, Giovanna Galliciott. Disruption of the autophagy-lysosome pathway is involved in neuropathology of the nclf mouse model of neuronal ceroid lipofuscinosis. PloS one. vol 7. issue 4. 2012-08-31. PMID:22536393. |
prominent autofluorescent and electron-dense lysosomal storage material was found in cerebellar purkinje cells, thalamus, hippocampus, olfactory bulb and in cortical layer ii to v. another prominent early feature of nclf pathogenesis was the localized astrocytosis that was evident in many brain regions and the more widespread microgliosis. |
2012-08-31 |
2023-08-12 |
mouse |
| Ratnakar Tripathi, Rajnikant Mishr. Aging-associated modulation in the expression of Pax6 in mouse brain. Cellular and molecular neurobiology. vol 32. issue 2. 2012-08-29. PMID:21901510. |
pax6 positive cells were significantly lower in dentate gyrus, ca1, ca2, and ca3 regions of hippocampus, in mitral cell (mice), and internal plexiform (inpl) layers of olfactory lobe, and in granular cell (grla), and purkinje's cell (puce) layers of cerebellum from p0 to old age. |
2012-08-29 |
2023-08-12 |
mouse |
| Letten F Saugsta. Further evidence that infantile autism is a chronic psychosis distinguished by a deficient delayed response function affecting the connections between hippocampus and singulum in its center, the SMA and the inhibitory Purkinje cells in cerebellum. Nutrition and health. vol 21. issue 1. 2012-08-02. PMID:22544774. |
further evidence that infantile autism is a chronic psychosis distinguished by a deficient delayed response function affecting the connections between hippocampus and singulum in its center, the sma and the inhibitory purkinje cells in cerebellum. |
2012-08-02 |
2023-08-12 |
Not clear |