| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Beverly W Baron, Peter Pyte. Expression Pattern of the BCL6 and ITM2B Proteins in Normal Human Brains and in Alzheimer Disease. Applied immunohistochemistry & molecular morphology : AIMM. vol 25. issue 7. 2018-01-24. PMID:26862951. |
itm2b is expressed in most cortical neurons, neurons of the hippocampus and dentate nucleus, cerebellar purkinje and granule cells, and (newly described here) in focal neurons in the basal ganglia, many neurons of the thalamus and brainstem, many cells in the ependyma and choroid plexus, and in the smooth muscle of blood vessels. |
2018-01-24 |
2023-08-13 |
human |
| Jerzy Wegiel, Michael Flory, Izabela Kuchna, Krzysztof Nowicki, Shuang Yong Ma, Jarek Wegiel, Eulalia Badmaev, Wayne P Silverman, Mony de Leon, Barry Reisberg, Thomas Wisniewsk. Multiregional Age-Associated Reduction of Brain Neuronal Reserve Without Association With Neurofibrillary Degeneration or β-Amyloidosis. Journal of neuropathology and experimental neurology. vol 76. issue 6. 2017-07-31. PMID:28505333. |
the study revealed the absence of significant neuronal loss in 7 regions and topographically selective reduction of neuronal reserve over 77 years in 8 brain structures including the entorhinal cortex (ec) (-33.3%), the second layer of the ec (-54%), cornu ammonis sector 1 (ca1) (-28.5%), amygdala, (-45.8%), thalamus (-40.5%), caudate nucleus (-35%), purkinje cells (-48.3%), and neurons in the dentate nucleus (40.1%). |
2017-07-31 |
2023-08-13 |
human |
| Takeshi Isozaki, Suguru Komenoi, Qiang Lu, Takako Usuki, Shuntaro Tomokata, Daisuke Matsutomo, Hiromichi Sakai, Kana Bando, Hiroshi Kiyonari, Fumio Sakan. Deficiency of diacylglycerol kinase η induces lithium-sensitive mania-like behavior. Journal of neurochemistry. vol 138. issue 3. 2017-06-14. PMID:27167678. |
the η isozyme of diacylglycerol kinase (dgk) is highly expressed in the hippocampus and purkinje cells in the central nervous system. |
2017-06-14 |
2023-08-13 |
mouse |
| T Meraz Medina, Jacinto Bañuelos Pineda, Carmen Cecilia Gómez Rodiles, Salvador Jiménez Vallejo, Ricardo Solís Zamora, Pedro Macedonio García Lópe. Identification of brain areas sensitive to the toxic effects of sparteine. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. vol 69. issue 1. 2017-03-14. PMID:27825754. |
the main brain structures sensitive to sparteine were the cerebral cortex (frontal, fronto-parietal and striate) olfactory and amygdaloid areas, the ventromedial hypothalamic nucleus, the purkinje cells in the cerebellum, and the ca1, ca3 and dentate gyrus regions of the hippocampus. |
2017-03-14 |
2023-08-13 |
rat |
| Qi Tian, James L Smart, Joachim H Clement, Yingming Wang, Alex Derkatch, Harald Schubert, Michael V Danilchik, Daniel L Marks, Lev M Fedoro. RHEB1 expression in embryonic and postnatal mouse. Histochemistry and cell biology. vol 145. issue 5. 2016-12-13. PMID:26708151. |
postnatal mice have broad spatial rheb1 expression in different regions of the cerebral cortex, subcortical regions (including hippocampus), olfactory bulb, medulla oblongata, and cerebellum (particularly in purkinje cells). |
2016-12-13 |
2023-08-13 |
mouse |
| Carolina Aguado, Sebastián García-Madrona, Mercedes Gil-Minguez, Rafael Lujá. Ontogenic Changes and Differential Localization of T-type Ca(2+) Channel Subunits Cav3.1 and Cav3.2 in Mouse Hippocampus and Cerebellum. Frontiers in neuroanatomy. vol 10. 2016-09-12. PMID:27616982. |
at the cellular and subcellular level, immunoelectron microscopy showed that labeling for cav3.1 was present in somato-dendritic domains of hippocampal interneurons and purkinje cells (pcs), while cav3.2 was present in somato-dendritic domains of ca1 pyramidal cells, hippocampal interneurons and pcs. |
2016-09-12 |
2023-08-13 |
mouse |
| Aikaterini S Papadopoulou, Lutgarde Serneels, Tilmann Achsel, Wim Mandemakers, Zsuzsanna Callaerts-Vegh, James Dooley, Pierre Lau, Torik Ayoubi, Enrico Radaelli, Marco Spinazzi, Melanie Neumann, Sébastien S Hébert, Asli Silahtaroglu, Adrian Liston, Rudi D'Hooge, Markus Glatzel, Bart De Stroope. Deficiency of the miR-29a/b-1 cluster leads to ataxic features and cerebellar alterations in mice. Neurobiology of disease. vol 73. 2016-08-29. PMID:25315682. |
the different members of the mir-29 family are strongly expressed in neurons of the olfactory bulb, the hippocampus and in the purkinje cells of the cerebellum. |
2016-08-29 |
2023-08-13 |
mouse |
| Robert Kraf. STIM and ORAI proteins in the nervous system. Channels (Austin, Tex.). vol 9. issue 5. 2016-08-19. PMID:26218135. |
stim2 is required for soce in hippocampal synapses and cortical neurons, whereas stim1 controls calcium store replenishment in cerebellar purkinje neurons. |
2016-08-19 |
2023-08-13 |
Not clear |
| Yu V Zarzhetskii, M Sh Avrushchenko, V V Moroz, T A Gudasheva, S B Seredeni. Effectiveness of GK-2, a Nerve Growth Factor Mimetic, in Preventing Post-Resuscitation Changes in the Brain. Bulletin of experimental biology and medicine. vol 159. issue 4. 2016-07-12. PMID:26388581. |
neurological status was assessed and the numbers of neurons per 1 mm in pyramidal neuronal layer length in ca1 and ca4 hippocampal fields and cerebellar purkinje cells were evaluated in albino male rats on post-resuscitation day 14 after 12-min cardiac arrest. |
2016-07-12 |
2023-08-13 |
rat |
| Isaac A Adedara, Olatunde Owoeye, Motunrayo A Aiyegbusi, Joshua O Dagunduro, Yetunde M Daramola, Ebenezer O Faromb. Kolaviron protects against benzo[a]pyrene-induced functional alterations along the brain-pituitary-gonadal axis in male rats. Environmental toxicology and pharmacology. vol 40. issue 2. 2016-06-29. PMID:26280929. |
light microscopy revealed severe necrosis of the purkinje cells in the cerebellum, neuronal degeneration of the cerebral cortex, neuronal necrosis of the hippocampus and testicular atrophy in b[a]p-treated rats. |
2016-06-29 |
2023-08-13 |
rat |
| Rocío Ruiz, Eva María Pérez-Villegas, Sara Bachiller, José Luis Rosa, José Angel Armengo. HERC 1 Ubiquitin Ligase Mutation Affects Neocortical, CA3 Hippocampal and Spinal Cord Projection Neurons: An Ultrastructural Study. Frontiers in neuroanatomy. vol 10. 2016-05-05. PMID:27147983. |
the main difference is that the reduction in the number of neurons affected in the tambaleante mutation in the neocortex, the hippocampus, and the spinal cord is not so evident as the dramatic loss of cerebellar purkinje cells. |
2016-05-05 |
2023-08-13 |
mouse |
| Stefanie Besser, Marit Sicker, Grit Marx, Ulrike Winkler, Volker Eulenburg, Swen Hülsmann, Johannes Hirrlinge. A Transgenic Mouse Line Expressing the Red Fluorescent Protein tdTomato in GABAergic Neurons. PloS one. vol 10. issue 6. 2016-04-19. PMID:26076353. |
robust expression was also observed in cortical and hippocampal neurons, purkinje cells in the cerebellum, amacrine cells in the retina as well as in cells migrating along the rostral migratory stream. |
2016-04-19 |
2023-08-13 |
mouse |
| B Ya Ryzhavskii, Ve M Litvintsev. Histochemical detection of 3β-hydroxysteroid dehydrogenase in neurons of rat brain. Bulletin of experimental biology and medicine. vol 152. issue 3. 2016-03-22. PMID:22803090. |
the maximum number of positive neurons was detected in the cerebellar cortex (purkinje cells) and hippocampus. |
2016-03-22 |
2023-08-12 |
rat |
| Eiji Mizutani, Mami Oikawa, Hidetoshi Kassai, Kimiko Inoue, Hirosuke Shiura, Ryutaro Hirasawa, Satoshi Kamimura, Shogo Matoba, Narumi Ogonuki, Hiroaki Nagatomo, Kuniya Abe, Teruhiko Wakayama, Atsu Aiba, Atsuo Ogur. Generation of cloned mice from adult neurons by direct nuclear transfer. Biology of reproduction. vol 92. issue 3. 2016-02-22. PMID:25653280. |
first, we used a specific antibody to discover cell types with reduced amounts of a repressive histone mark-dimethylated histone h3 lysine 9 (h3k9me2)-and identified ca1 pyramidal cells in the hippocampus and purkinje cells in the cerebellum as candidates. |
2016-02-22 |
2023-08-13 |
mouse |
| Meenakshi Malhotra, Catherine Tomaro-Duchesneau, Shyamali Saha, Satya Prakas. Intranasal, siRNA Delivery to the Brain by TAT/MGF Tagged PEGylated Chitosan Nanoparticles. Journal of pharmaceutics. vol 2013. 2015-11-11. PMID:26555995. |
the results indicate that 0.5 mg/kg of sirna is delivered successfully to the hippocampus, thalamus, hypothalamus, and purkinje cells in the cerebellum after 4 hrs of post intranasal delivery. |
2015-11-11 |
2023-08-13 |
Not clear |
| Sophie Martin, Latifa Zekri, Alexandra Metz, Tangui Maurice, Karim Chebli, Michel Vignes, Jamal Taz. Deficiency of G3BP1, the stress granules assembly factor, results in abnormal synaptic plasticity and calcium homeostasis in neurons. Journal of neurochemistry. vol 125. issue 2. 2015-08-18. PMID:23373770. |
immunohistochemistry pinpointed high expression of g3bp in the cytoplasm of hippocampal neurons and purkinje cells of the cerebellum of wild-type mice. |
2015-08-18 |
2023-08-12 |
mouse |
| Kirsten Ridder, Sascha Keller, Maria Dams, Anne-Kathleen Rupp, Jessica Schlaudraff, Domenico Del Turco, Julia Starmann, Jadranka Macas, Darja Karpova, Kavi Devraj, Candan Depboylu, Britta Landfried, Bernd Arnold, Karl H Plate, Günter Höglinger, Holger Sültmann, Peter Altevogt, Stefan Momm. Extracellular vesicle-mediated transfer of genetic information between the hematopoietic system and the brain in response to inflammation. PLoS biology. vol 12. issue 6. 2015-08-05. PMID:24893313. |
although cre-mediated recombination events in the brain occur very rarely in healthy animals, their number increases considerably in different injury models, particularly under inflammatory conditions, and extend beyond purkinje neurons to other neuronal populations in cortex, hippocampus, and substantia nigra. |
2015-08-05 |
2023-08-13 |
mouse |
| Takako Usuki, Hiromichi Sakai, Takao Shionoya, Naruki Sato, Fumio Sakan. Expression and localization of type II diacylglycerol kinase isozymes δ and η in the developing mouse brain. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 63. issue 1. 2015-07-08. PMID:25362140. |
a substantial amount of dgkη (η1/η2) was detected in layers ii-vi of the cerebral cortex, ca1 and ca2 regions and dentate gyrus of the hippocampus, mitral cell and glomerular layers of the olfactory bulb, and purkinje cells in the cerebellum of 1- to 32-week-old mice. |
2015-07-08 |
2023-08-13 |
mouse |
| Xiaohong Song, Miwako Yamasaki, Taisuke Miyazaki, Kohtarou Konno, Motokazu Uchigashima, Masahiko Watanab. Neuron type- and input pathway-dependent expression of Slc4a10 in adult mouse brains. The European journal of neuroscience. vol 40. issue 5. 2015-05-25. PMID:24905082. |
slc4a10 mrna was widely expressed, with higher levels in pyramidal cells in the hippocampus and cerebral cortex, parvalbumin-positive interneurons in the hippocampus, and purkinje cells (pcs) in the cerebellum. |
2015-05-25 |
2023-08-13 |
mouse |
| Markus Damme, Laura Brandenstein, Susanne Fehr, Wanda Jankowiak, Udo Bartsch, Michaela Schweizer, Irm Hermans-Borgmeyer, Stephan Storc. Gene disruption of Mfsd8 in mice provides the first animal model for CLN7 disease. Neurobiology of disease. vol 65. 2014-11-13. PMID:24423645. |
lysosomal storage was found in large neurons of the medulla, the hippocampus and in purkinje cells of the cerebellum in mutant mice. |
2014-11-13 |
2023-08-12 |
mouse |