| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Congyao Zha, Carole A Farah, Vladimir Fonov, David A Rudko, Wayne S Sossi. MRI of Capn15 Knockout Mice and Analysis of Capn 15 Distribution Reveal Possible Roles in Brain Development and Plasticity. Neuroscience. vol 465. 2021-06-04. PMID:33951504. |
based on β-galactosidase expression in an insert strain where lacz is expressed under the control of the capn15 promoter, we show that capn15 is expressed in adult mice, particularly in neurons involved in plasticity such as the hippocampus, lateral amygdala and purkinje neurons, and partially in other non-characterized cell types. |
2021-06-04 |
2023-08-13 |
mouse |
| Tayebeh Noori, Ahmad Reza Dehpour, Antoni Sureda, Sajad Fakhri, Eduardo Sobarzo-Sanchez, Mohammad Hosein Farzaei, Esra Küpeli Akkol, Zahra Khodarahmi, Seyede Zahra Hosseini, Seyede Darya Alavi, Samira Shirooi. The role of glycogen synthase kinase 3 beta in multiple sclerosis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 132. 2021-02-25. PMID:33080467. |
gsk-3 occurs in mammals in two isoforms gsk-3α and gsk-3β, both of which are common in the brain, although gsk-3α is found particularly in the cerebral cortex, cerebellum, striated hippocampus and purkinje cells, while gsk-3β is found in all brain regions. |
2021-02-25 |
2023-08-13 |
Not clear |
| Juan Alejandro Oliva Trejo, Isei Tanida, Chigure Suzuki, Soichiro Kakuta, Norihiro Tada, Yasuo Uchiyam. Characterization of starvation-induced autophagy in cerebellar Purkinje cells of pHluorin-mKate2-human LC3B transgenic mice. Scientific reports. vol 10. issue 1. 2020-12-10. PMID:32541814. |
histological analysis revealed fluorescent puncta in neurons of the cerebral cortex, hippocampus, cerebellar purkinje cells, and anterior spinal regions. |
2020-12-10 |
2023-08-13 |
mouse |
| Saaki Tamura, Yukiko Yasuoka, Hiromi Miura, Gou Takahashi, Masahiro Sato, Masato Ohtsuk. Thy1 promoter activity in the Rosa26 locus in mice: lessons from Dre-rox conditional expression system. Experimental animals. vol 69. issue 3. 2020-08-31. PMID:32051391. |
the thy1 promoter targeted to the rosa26 locus appeared active in virtually all purkinje cells in the cerebellum and hippocampus. |
2020-08-31 |
2023-08-13 |
mouse |
| Yunan Gao, Elaine E Irvine, Ioanna Eleftheriadou, Carlos Jiménez Naranjo, Francesca Hearn-Yeates, Leontien Bosch, Justyna A Glegola, Leah Murdoch, Aleksandra Czerniak, Ilaria Meloni, Alessandra Renieri, Maria Kinali, Nicholas D Mazaraki. Gene replacement ameliorates deficits in mouse and human models of cyclin-dependent kinase-like 5 disorder. Brain : a journal of neurology. vol 143. issue 3. 2020-07-06. PMID:32125365. |
transgene brain expression was sporadic at the cellular level and most prominent in hippocampal neurons and cerebellar purkinje cells. |
2020-07-06 |
2023-08-13 |
mouse |
| Murad Alturkustani, Lee-Cyn An. Claustral neurons are vulnerable to ischemic insults in cardiac arrest encephalopathy. International journal of clinical and experimental pathology. vol 11. issue 5. 2020-01-19. PMID:31938390. |
selective vulnerability is the common form of ischemic injury in these cases and commonly affects the ca1 of hippocampus, cerebral cortex in watershed zone and purkinje cells of the cerebellum. |
2020-01-19 |
2023-08-13 |
Not clear |
| Katarzyna O Rojek, Joanna Krzemień, Hubert Doleżyczek, Paweł M Boguszewski, Leszek Kaczmarek, Witold Konopka, Marcin Rylski, Jacek Jaworski, Lars Holmgren, Tomasz J Prószyńsk. Amot and Yap1 regulate neuronal dendritic tree complexity and locomotor coordination in mice. PLoS biology. vol 17. issue 5. 2019-12-16. PMID:31042703. |
we found that amot is a critical mediator of dendritic morphogenesis in cultured hippocampal cells and purkinje cells in the brain. |
2019-12-16 |
2023-08-13 |
mouse |
| Kiyotoshi Satoh, Tsuyoshi Morishita, Keiko Haraguchi, Naoto Kakinuma, Tetsu Akiyama, T. Send. Expression and localization of the LGN protein in the mouse brain with reference to its relationship with Galphai2. Medical electron microscopy : official journal of the Clinical Electron Microscopy Society of Japan. vol 32. issue 4. 2019-11-20. PMID:11810449. |
immunofluorescence microscopy showed that lgn is localized in nuclei of the neurons in the olfactory bulb, cerebral cortex, and hippocampus, but in both nuclei and cytoplasm of purkinje cells in the cerebellum. |
2019-11-20 |
2023-08-12 |
mouse |
| Giti Garthwaite, John Garthwait. AMPA Neurotoxicity in Rat Cerebellar and Hippocampal Slices: Histological Evidence for Three Mechanisms. The European journal of neuroscience. vol 3. issue 8. 2019-11-20. PMID:12106458. |
in cerebellar slices, ampa induced the degeneration of most purkinje cells together with a population of golgi cells; in hippocampal slices the neurons were affected in the order ca3 > ca1 > dentate granule cells. |
2019-11-20 |
2023-08-12 |
rat |
| Giti Garthwaite, John Garthwait. AMPA Neurotoxicity in Rat Cerebellar and Hippocampal Slices: Histological Evidence for Three Mechanisms. The European journal of neuroscience. vol 3. issue 8. 2019-11-20. PMID:12106458. |
cerebellar golgi cells) underwent a rapid degeneration; a delayed one in which the neurons (purkinje cells and hippocampal neurons) appeared to be only mildly affected immediately after a 30 min exposure but then underwent a protracted degeneration during the postincubation period (1.5 - 3 h); and finally a slow toxicity, which took place during long (2 h) exposures to ampa (3 - 30 microm). |
2019-11-20 |
2023-08-12 |
rat |
| Matthieu M Vermeren, Qifeng Zhang, Elizabeth Smethurst, Anne Segonds-Pichon, Heinrich Schrewe, Michael J O Wakela. The Phospholipase D2 Knock Out Mouse Has Ectopic Purkinje Cells and Suffers from Early Adult-Onset Anosmia. PloS one. vol 11. issue 9. 2019-11-20. PMID:27658289. |
the expression pattern lead us to specifically examine the mitral cells of olfactory bulbs, the cornus amonis (ca) regions of the hippocampus and the purkinje cells of the cerebellum. |
2019-11-20 |
2023-08-13 |
mouse |
| Julie Marie Lefort, Jean Vincent, Lucille Tallot, Frédéric Jarlier, Chris Innocentius De Zeeuw, Laure Rondi-Reig, Christelle Rochefor. Impaired cerebellar Purkinje cell potentiation generates unstable spatial map orientation and inaccurate navigation. Nature communications. vol 10. issue 1. 2019-07-01. PMID:31113954. |
cerebellar activity supported by pkc-dependent long-term depression in purkinje cells (pcs) is involved in the stabilization of self-motion based hippocampal representation, but the existence of cerebellar processes underlying integration of allocentric cues remains unclear. |
2019-07-01 |
2023-08-13 |
mouse |
| Chuan Qin, Shan-Qiu Wu, Bao-Sheng Chen, Xiao-Xian Wu, Kun-Yao Qu, Jun-Min Liu, Gui-Fang Zhang, Yan-Feng Xu, Shunli Shu, Lihua Sun, Yan-Yong Li, Hua Zhu, Lan Huang, Chun-Mei Ma, Yu-Huan Xu, Yun-Lin Han, Yao-Zeng L. Pathological Changes in APP/PS-1 Transgenic Mouse Models of Alzheimer's Disease Treated with Ganoderma Lucidum Preparation. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. vol 39. issue 4. 2019-02-11. PMID:28877835. |
results the senile plaques and neurofibrillar tangles in the cerebrum and cerebellum were dissolved or disappeared in lz-h and lz-m groups.decrease of amyloid angiopathy was found in lz-h and lz-m groups.the immature neurons appeared more in hippocampus and dentate nucleus of lz-h and lz-m groups than those in ad model and donepezil hydrochloride groups(hippcampus:f=1.738,p=0.016;dentate nucleus:f=1.924,p=0.026),and these immature neurons differentiated to be neurons.more purkinje cells loss occurred in ad model mice than that in lz-h and lz-m groups(f=9.46,p=0.007;f=9.46,p=0.010).the lz-h and lz-m groups had more new neuron stem cells grown up in cerebellum.electromicroscopic examination showed the hippocampal neurons in lz-h and lz-m group were integrated,the nuclear membrane was intact,and the mitochondria in the cytoplasm,endoplasmic reticulum,golgi bodies,microtubules,and synapses were also complete.the microglial cell showed no abnormality.no toxicity appeared in the pathological specimens of mice treated with ganoderma lucidum preparation.conclusion the ganoderma lucidum preparation can dissolve and decline or dismiss the senile plaques and neurofibrillar tangles in the brain of ad mice and also reduce the amyloid angiopathy. |
2019-02-11 |
2023-08-13 |
mouse |
| Kristen R Montgomery, A S C Louis Sam Titus, Lulu Wang, Santosh R D'Mell. Elevated MeCP2 in Mice Causes Neurodegeneration Involving Tau Dysregulation and Excitotoxicity: Implications for the Understanding and Treatment of MeCP2 Triplication Syndrome. Molecular neurobiology. vol 55. issue 12. 2019-01-18. PMID:29637441. |
loss of cortical and hippocampal neurons may explain the mental retardation and epilepsy in patients, whereas ataxia likely results from the loss of purkinje neurons. |
2019-01-18 |
2023-08-13 |
mouse |
| Takefumi Uemura, Naoki Sawada, Takao Sakaba, Satoshi Kametaka, Masaya Yamamoto, Satoshi Wagur. Intracellular localization of GGA accessory protein p56 in cell lines and central nervous system neurons. Biomedical research (Tokyo, Japan). vol 39. issue 4. 2018-11-08. PMID:30101838. |
using immunohistofluorescence microscopy in the mouse central nervous system (cns), p56 was clearly detected as scattered cytoplasmic puncta in spinal motor neurons, cerebellar purkinje cells, and pyramidal neurons of the hippocampus and cerebral cortex. |
2018-11-08 |
2023-08-13 |
mouse |
| Yvonne S Davidson, Andrew C Robinson, Sara Rollinson, Stuart Pickering-Brown, Shangxi Xiao, Janice Robertson, David M A Man. Immunohistochemical detection of C9orf72 protein in frontotemporal lobar degeneration and motor neurone disease: patterns of immunostaining and an evaluation of commercial antibodies. Amyotrophic lateral sclerosis & frontotemporal degeneration. vol 19. issue 1-2. 2018-09-06. PMID:28766957. |
similar staining was seen in purkinje cells in healthy control tissues and in other neurodegenerative disorders, and in pyramidal cells of ca4 and dentate gyrus of hippocampus. |
2018-09-06 |
2023-08-13 |
Not clear |
| Elizabeth Bautista, Natanael Zarco, Nicolás Aguirre-Pineda, Manuel Lara-Lozano, Paula Vergara, Juan Antonio González-Barrios, Raúl Aguilar-Roblero, José Segovi. Expression of Gas1 in Mouse Brain: Release and Role in Neuronal Differentiation. Cellular and molecular neurobiology. vol 38. issue 4. 2018-09-04. PMID:29110208. |
moreover, we detected the expression and release of gas1 from primary cultures of purkinje cells and from hippocampal neurons as well as from neuronal cell lines, but not from cerebellar granular cells. |
2018-09-04 |
2023-08-13 |
mouse |
| Stephanie M Miller, Viskasari P Kalanjati, Paul B Colditz, Stella Tracey Björkma. Developmental Changes in Expression of GABAA Receptor Subunits α1, α2, and α3 in the Pig Brain. Developmental neuroscience. vol 39. issue 5. 2018-05-22. PMID:28472809. |
immunofluorescent labelling revealed α1 expression on the somatic membranes of pyramidal cells in the cortex and hippocampus, and in the cerebellar purkinje cells. |
2018-05-22 |
2023-08-13 |
human |
| Yasukazu Hozumi, Hiroki Fujiwara, Kenya Kaneko, Satoshi Fujii, Matthew K Topham, Masahiko Watanabe, Kaoru Got. Diacylglycerol kinase ε localizes to subsurface cisterns of cerebellar Purkinje cells. Cell and tissue research. vol 368. issue 3. 2018-02-14. PMID:28191598. |
dgkε was richly expressed in principal neurons of higher brain regions, including pyramidal cells in the hippocampus and neocortex, medium spiny neurons in the striatum and purkinje cells in the cerebellum. |
2018-02-14 |
2023-08-13 |
mouse |
| Shaymaa Hussein, Abdel-Aleem El-Saba, Mona K Gala. Biochemical and histological studies on adverse effects of mobile phone radiation on rat's brain. Journal of chemical neuroanatomy. vol 78. 2018-02-01. PMID:27474378. |
degenerative changes were observed in the hippocampus pyramidal cells, dark cells and cerebellar purkinje cells with vascular congestion. |
2018-02-01 |
2023-08-13 |
rat |