| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Brands, P A Münzel, K W Boc. In situ hybridization studies of UDP-glucuronosyltransferase UGT1A6 expression in rat testis and brain. Biochemical pharmacology. vol 59. issue 11. 2000-05-04. PMID:10751554. |
it was found that ugt1a6 is expressed in sertoli cells and spermatogonia of rat testis and in brain neurons, in particular in hippocampal pyramidal cells and purkinje cells of the cerebellum. |
2000-05-04 |
2023-08-12 |
rat |
| C C Gandhi, R M Kelly1, R G Wiley, T J Wals. Impaired acquisition of a Morris water maze task following selective destruction of cerebellar purkinje cells with OX7-saporin. Behavioural brain research. vol 109. issue 1. 2000-05-03. PMID:10699656. |
bilateral icv injections of 2 microg ox7-saporin (4 microg total) in adult male rats produced substantial loss of purkinje cells (56%) throughout the cerebellum without affecting hippocampal morphology or biochemical indices of cholinergic, serotonergic, or catecholaminergic function in the hippocampus, frontal cortex, or striatum. |
2000-05-03 |
2023-08-12 |
mouse |
| S Lee, Y Takeda, H Kawano, H Hosoya, M Nomoto, D Fujimoto, N Takahashi, K Watanab. Expression and regulation of a gene encoding neural recognition molecule NB-3 of the contactin/F3 subgroup in mouse brain. Gene. vol 245. issue 2. 2000-05-02. PMID:10717476. |
in situ hybridization demonstrated that nb-3 mrna was preferentially expressed in the accessory olfactory bulb, layers ii/iii and v of the cerebral cortex, piriform cortex, anterior thalamic nuclei, locus coeruleus of the pons and mesencephalic trigeminal nucleus, and in purkinje cells of the cerebellum. |
2000-05-02 |
2023-08-12 |
mouse |
| J S Liu, Y Y Chang, H S Wu, C Y Huang, W H Chen, M Y Lan, Y F Kao, S S Che. Transtentorial cerebellar c-jun expression after focal cerebral cortical injury in mice. Neuroscience letters. vol 282. issue 1-2. 2000-04-28. PMID:10713402. |
a distinct increment of c-jun protein expression in purkinje cells of the bilateral cerebellar hemispheres with focal connotation in the vermis was detected since 1 week postinjury. |
2000-04-28 |
2023-08-12 |
mouse |
| N Chiesa, C Barlow, A Wynshaw-Boris, P Strata, F Tempi. Atm-deficient mice Purkinje cells show age-dependent defects in calcium spike bursts and calcium currents. Neuroscience. vol 96. issue 3. 2000-04-27. PMID:10717437. |
neurological deterioration is the major cause of death in ataxia telangiectasia patients: in the cerebellum, mainly purkinje cells are affected. |
2000-04-27 |
2023-08-12 |
mouse |
| P Chomez, I Neveu, A Mansén, E Kiesler, L Larsson, B Vennström, E Arena. Increased cell death and delayed development in the cerebellum of mice lacking the rev-erbA(alpha) orphan receptor. Development (Cambridge, England). vol 127. issue 7. 2000-04-26. PMID:10704394. |
however, during the second week of life, the cerebellum of rev-erba(alpha) mutants presents several unexpected abnormalities, such as alterations in the development of purkinje cells, delay in the proliferation and migration of granule cells from the external granule cell layer and increased apoptosis of neurons in the internal granule cell layer. |
2000-04-26 |
2023-08-12 |
mouse |
| M D Womack, J W Walker, K Khodakha. Impaired calcium release in cerebellar Purkinje neurons maintained in culture. The Journal of general physiology. vol 115. issue 3. 2000-04-24. PMID:10694261. |
our findings suggest that cultured purkinje cells are an unfaithful experimental model for the study of the role of calcium release in the induction of cerebellar long term depression. |
2000-04-24 |
2023-08-12 |
Not clear |
| T A Maldonado, R E Jones, D O Norri. Distribution of beta-amyloid and amyloid precursor protein in the brain of spawning (senescent) salmon: a natural, brain-aging model. Brain research. vol 858. issue 2. 2000-04-24. PMID:10708675. |
intra- and extra-neuronal abeta(1-42) immunoreactivity (abeta-ir) were present in all app-ir regions except the nucleus lateralis tuberis and purkinje cells of the cerebellum (coordination). |
2000-04-24 |
2023-08-12 |
human |
| P R Borghesani, F W Alt, A Bottaro, L Davidson, S Aksoy, G A Rathbun, T M Roberts, W Swat, R A Segal, Y G. Abnormal development of Purkinje cells and lymphocytes in Atm mutant mice. Proceedings of the National Academy of Sciences of the United States of America. vol 97. issue 7. 2000-04-24. PMID:10716718. |
even though we found no gross cerebellar degeneration in older atm(y/y) animals, ectopic and abnormally differentiated purkinje cells were apparent in mutant mice of all ages. |
2000-04-24 |
2023-08-12 |
mouse |
| T Hasegawa, K Yamaguchi, T Wada, A Takeda, Y Itoyama, T Miyag. Molecular cloning of mouse ganglioside sialidase and its increased expression in Neuro2a cell differentiation. The Journal of biological chemistry. vol 275. issue 11. 2000-04-12. PMID:10713120. |
in situ hybridization of mouse brain demonstrated the mrna to be present in the cerebral cortex, as well as in the granule cell layer, purkinje cells, and deep cerebellar nucleus of the cerebellum. |
2000-04-12 |
2023-08-12 |
mouse |
| K A Takahashi, D J Linde. Cannabinoid receptor modulation of synapses received by cerebellar Purkinje cells. Journal of neurophysiology. vol 83. issue 3. 2000-04-11. PMID:10712447. |
therefore the effects of exogenous cannabinoids on synapses received by purkinje cells were investigated in rat cerebellar slices. |
2000-04-11 |
2023-08-12 |
rat |
| C A Dlugos, R J Pentne. Effects of chronic ethanol consumption on SER of Purkinje neurons in old F344 rats. Alcohol (Fayetteville, N.Y.). vol 20. issue 2. 2000-04-11. PMID:10719791. |
electron microscopy of cerebellar preparations was used to analyze morphological alterations in ser profile size within the dendritic shafts and spines of purkinje neurons. |
2000-04-11 |
2023-08-12 |
rat |
| W Darmanto, M Inouye, Y Takagishi, M Ogawa, K Mikoshiba, Y Murat. Derangement of Purkinje cells in the rat cerebellum following prenatal exposure to X-irradiation: decreased Reelin level is a possible cause. Journal of neuropathology and experimental neurology. vol 59. issue 3. 2000-04-07. PMID:10744063. |
derangement of purkinje cells in the rat cerebellum following prenatal exposure to x-irradiation: decreased reelin level is a possible cause. |
2000-04-07 |
2023-08-12 |
rat |
| W Darmanto, M Inouye, Y Takagishi, M Ogawa, K Mikoshiba, Y Murat. Derangement of Purkinje cells in the rat cerebellum following prenatal exposure to X-irradiation: decreased Reelin level is a possible cause. Journal of neuropathology and experimental neurology. vol 59. issue 3. 2000-04-07. PMID:10744063. |
it has been reported that prenatal x-irradiation of rats during the late gestation period causes heterotopic purkinje cells in the internal granular layer (igl) of the abnormally foliated cerebellum. |
2000-04-07 |
2023-08-12 |
rat |
| W Darmanto, M Inouye, Y Takagishi, M Ogawa, K Mikoshiba, Y Murat. Derangement of Purkinje cells in the rat cerebellum following prenatal exposure to X-irradiation: decreased Reelin level is a possible cause. Journal of neuropathology and experimental neurology. vol 59. issue 3. 2000-04-07. PMID:10744063. |
pregnant rats (n = 22) were exposed to 2.5 gy x-radiation on gestation day 21 and the cerebellum of progeny was examined histologically and by immunohistochemistry to identify purkinje and bergmann cells. |
2000-04-07 |
2023-08-12 |
rat |
| W Darmanto, M Inouye, Y Takagishi, M Ogawa, K Mikoshiba, Y Murat. Derangement of Purkinje cells in the rat cerebellum following prenatal exposure to X-irradiation: decreased Reelin level is a possible cause. Journal of neuropathology and experimental neurology. vol 59. issue 3. 2000-04-07. PMID:10744063. |
by postnatal day (p) 9, while purkinje cells with well-developed dendrites aligned underneath the egl in the control cerebellum, purkinje cells with shorter and abnormally oriented dendrites failed to align and remained in the heterotopic location in the igl. |
2000-04-07 |
2023-08-12 |
rat |
| D Driemeier, E M Colodel, E J Gimeno, S S Barro. Lysosomal storage disease caused by Sida carpinifolia poisoning in goats. Veterinary pathology. vol 37. issue 2. 2000-04-05. PMID:10714644. |
ultrastructural changes included membrane-bound vacuoles in hepatocytes, kupffer cells, acinar pancreatic cells, purkinje cells, and the small neurons of the granular cell layer of the cerebellum. |
2000-04-05 |
2023-08-12 |
Not clear |
| A Buffo, M Zagrebelsky, A B Huber, A Skerra, M E Schwab, P Strata, F Ross. Application of neutralizing antibodies against NI-35/250 myelin-associated neurite growth inhibitory proteins to the adult rat cerebellum induces sprouting of uninjured purkinje cell axons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 6. 2000-04-03. PMID:10704503. |
we have recently shown that application of neutralizing in-1 antibody fab fragment against ni-35/250 proteins to the adult cerebellum induces the expression of injury/growth-associated markers in intact purkinje cells. |
2000-04-03 |
2023-08-12 |
rat |
| A Buffo, M Zagrebelsky, A B Huber, A Skerra, M E Schwab, P Strata, F Ross. Application of neutralizing antibodies against NI-35/250 myelin-associated neurite growth inhibitory proteins to the adult rat cerebellum induces sprouting of uninjured purkinje cell axons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 6. 2000-04-03. PMID:10704503. |
a single intraparenchymal application of in-1 fab fragment to the adult cerebellum induces a profuse sprouting of purkinje axons along their intracortical course. |
2000-04-03 |
2023-08-12 |
rat |
| A Buffo, M Zagrebelsky, A B Huber, A Skerra, M E Schwab, P Strata, F Ross. Application of neutralizing antibodies against NI-35/250 myelin-associated neurite growth inhibitory proteins to the adult rat cerebellum induces sprouting of uninjured purkinje cell axons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 6. 2000-04-03. PMID:10704503. |
functional neutralization of ni-35/250 proteins induces outgrowth from uninjured purkinje neurites in the adult cerebellum. |
2000-04-03 |
2023-08-12 |
rat |