| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Kubosaki, A Ueno, Y Matsumoto, K Doi, K Saeki, T Onoder. Analysis of prion protein mRNA by in situ hybridization in brain and placenta of sheep. Biochemical and biophysical research communications. vol 273. issue 3. 2000-09-08. PMID:10891342. |
in sheep brain, prp mrna was predominantly localized within large neocortical neurons in the cerebrum, purkinje cells and neurons of the molecular and granule cell layers in the cerebellum. |
2000-09-08 |
2023-08-12 |
Not clear |
| H Yamamoto, T Ochiya, Y Takahama, Y Ishii, N Osumi, H Sakamoto, M Terad. Detection of spatial localization of Hst-1/Fgf-4 gene expression in brain and testis from adult mice. Oncogene. vol 19. issue 33. 2000-09-07. PMID:10949936. |
cell type-specific gene expression was detected: purkinje cells in the cerebellum and sertoli cells in testis. |
2000-09-07 |
2023-08-12 |
mouse |
| C Strazielle, R Lalonde, T A Reade. Autoradiography of glutamate receptor binding in adult Lurcher mutant mice. Journal of neuropathology and experimental neurology. vol 59. issue 8. 2000-08-30. PMID:10952061. |
in cerebellum, there were postsynaptic ampa and metabotropic receptors on purkinje cells, postsynaptic nmda receptors on granule cells, as well as ka receptors on granule cells or on parallel fibers. |
2000-08-30 |
2023-08-12 |
mouse |
| T Verjat, A Dhénaut, J P Radicella, S Araned. Detection of 8-oxoG DNA glycosylase activity and OGG1 transcripts in the rat CNS. Mutation research. vol 460. issue 2. 2000-08-29. PMID:10882853. |
following in situ hybridization with radiolabeled ogg1 cdna or specific antisense oligonucleotides, ogg1 transcripts showed a widespread but heterogeneous distribution pattern among distinct brain regions of adult rats: high levels of this transcript were detected in the ca1-ca3 layers and the gyrus dentate of the hippocampal formation, the piriform cortex, the supraoptic nuclei, the olivary complex as well as in the pyramidal cells of layer v of the cortex and the purkinje cells of the cerebellum. |
2000-08-29 |
2023-08-12 |
rat |
| N S Heiss, D Bächner, R Salowsky, A Kolb, P Kioschis, A Poustk. Gene structure and expression of the mouse dyskeratosis congenita gene, dkc1. Genomics. vol 67. issue 2. 2000-08-29. PMID:10903840. |
in addition, higher level dkc1 expression was confined to embryonic neural tissues as well as to specific neurons in the cerebellum (purkinje cells) and the olfactory bulb (mitral cells) of the adult brain. |
2000-08-29 |
2023-08-12 |
mouse |
| C Misra, S G Brickley, D J Wyllie, S G Cull-Cand. Slow deactivation kinetics of NMDA receptors containing NR1 and NR2D subunits in rat cerebellar Purkinje cells. The Journal of physiology. vol 525 Pt 2. 2000-08-28. PMID:10835034. |
we have examined the deactivation kinetics of native n-methyl-d-aspartate receptors (nmdars) containing nr1 and nr2d subunits by patch-clamp recording from purkinje cells in cerebellar slices from young rats. |
2000-08-28 |
2023-08-12 |
rat |
| B L Hylander, X Chen, P C Graf, J R Subjec. The distribution and localization of hsp110 in brain. Brain research. vol 869. issue 1-2. 2000-08-25. PMID:10865058. |
in contrast, in the cerebellum, the purkinje cells are the major hsp110 containing cells while the more abundant granule cells show little if any hsp110 labeling. |
2000-08-25 |
2023-08-12 |
mouse |
| S Tanaka, M Saito, M Morimatsu, E Oham. Immunohistochemical studies of the PrP(CJD) deposition in Creutzfeldt-Jakob disease. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 20. issue 2. 2000-08-17. PMID:10935449. |
interestingly, the purkinje cells had no positivity for prp(cjd) in all cases, although the neurons in relatively preserved cerebellum showed apparent positivity for synaptophysin. |
2000-08-17 |
2023-08-12 |
Not clear |
| H Hirata, T Ohtsuka, Y Bessho, R Kageyam. Generation of structurally and functionally distinct factors from the basic helix-loop-helix gene Hes3 by alternative first exons. The Journal of biological chemistry. vol 275. issue 25. 2000-08-16. PMID:10858455. |
the basic helix-loop-helix gene hes3 is expressed by differentiating and mature purkinje cells in the cerebellum and by neural precursor cells in the embryonal nervous system. |
2000-08-16 |
2023-08-12 |
Not clear |
| M Lee, Y Jo, M Chun, J Chung, M Kim, D Mi. Immunohistochemical localization of phospholipase D1 in rat central nervous system. Brain research. vol 864. issue 1. 2000-08-11. PMID:10793186. |
purkinje cells and deep cerebellar nuclei of the cerebellum were also labeled intensely. |
2000-08-11 |
2023-08-12 |
rat |
| F Metzger, J P Kapfhamme. Protein kinase C activity modulates dendritic differentiation of rat Purkinje cells in cerebellar slice cultures. The European journal of neuroscience. vol 12. issue 6. 2000-08-11. PMID:10886339. |
protein kinase c activity modulates dendritic differentiation of rat purkinje cells in cerebellar slice cultures. |
2000-08-11 |
2023-08-12 |
rat |
| F Metzger, J P Kapfhamme. Protein kinase C activity modulates dendritic differentiation of rat Purkinje cells in cerebellar slice cultures. The European journal of neuroscience. vol 12. issue 6. 2000-08-11. PMID:10886339. |
we used slice cultures from rat cerebellum of postnatal day 8 to investigate the effect of protein kinase c (pkc) activity on dendritic development of purkinje cells. |
2000-08-11 |
2023-08-12 |
rat |
| T Knöpfel, D Anchisi, M E Alojado, F Tempia, P Strat. Elevation of intradendritic sodium concentration mediated by synaptic activation of metabotropic glutamate receptors in cerebellar Purkinje cells. The European journal of neuroscience. vol 12. issue 6. 2000-08-11. PMID:10886360. |
brief tetanic stimulation of parallel fibers in rat and mouse cerebellar slices evokes a slow excitatory postsynaptic current in purkinje cells that is mediated by the mglur1 subtype of metabotropic glutamate receptors. |
2000-08-11 |
2023-08-12 |
mouse |
| M Turmaine, A Raza, A Mahal, L Mangiarini, G P Bates, S W Davie. Nonapoptotic neurodegeneration in a transgenic mouse model of Huntington's disease. Proceedings of the National Academy of Sciences of the United States of America. vol 97. issue 14. 2000-08-10. PMID:10869421. |
in this study, we report that all lines of these mice develop a late onset neurodegeneration within the anterior cingulate cortex, dorsal striatum, and of the purkinje neurons of the cerebellum. |
2000-08-10 |
2023-08-12 |
mouse |
| O Castejón, P Sim. Cytoarchitectonic arrangement and intracortical circuits of hamster cerebellum. A study by means of confocal scanning laser microscopy. Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al. vol 23. issue 3. 2000-08-10. PMID:10904543. |
cerebellar macroneurons (golgi and purkinje cells) and microneurons (granule, basket and stellate cells) showed optimal intracellular staining of cell soma, axonal and proximal dendritic processes. |
2000-08-10 |
2023-08-12 |
Not clear |
| Y Mori, M Wakamori, S Oda, C F Fletcher, N Sekiguchi, E Mori, N G Copeland, N A Jenkins, K Matsushita, Z Matsuyama, K Imot. Reduced voltage sensitivity of activation of P/Q-type Ca2+ channels is associated with the ataxic mouse mutation rolling Nagoya (tg(rol)). The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 15. 2000-08-10. PMID:10908603. |
furthermore, somatic whole-cell recording of mutant purkinje cells displayed only abortive na(+) burst activity and hardly exhibited ca(2+) spike activity in cerebellar slices. |
2000-08-10 |
2023-08-12 |
mouse |
| S Matsuda, T Launey, S Mikawa, H Hira. Disruption of AMPA receptor GluR2 clusters following long-term depression induction in cerebellar Purkinje neurons. The EMBO journal. vol 19. issue 12. 2000-08-07. PMID:10856222. |
here, using cultured purkinje cells, we show that stimulations inducing cerebellar ltd cause phosphorylation of ser880 in the intracellular c-terminal domain of the ampa receptor subunit glur2. |
2000-08-07 |
2023-08-12 |
Not clear |
| K V Gregg, G A Bishop, J S Kin. Fine structural analysis of calcitonin gene-related peptide in the mouse inferior olivary complex. Journal of neurocytology. vol 28. issue 6. 2000-08-03. PMID:10767096. |
climbing fiber afferents to the cerebellum, from the inferior olivary complex, have a powerful excitatory effect on purkinje cells. |
2000-08-03 |
2023-08-12 |
mouse |
| H Hirai, T Laune. The regulatory connection between the activity of granule cell NMDA receptors and dendritic differentiation of cerebellar Purkinje cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 14. 2000-08-03. PMID:10884305. |
here, using cerebellar neuronal culture, we show that the activation of nmda receptors expressed by granule cells triggers the signaling pathway for the dendritic differentiation of purkinje cells. |
2000-08-03 |
2023-08-12 |
Not clear |
| P Barili, E Bronzetti, A Ricci, D Zaccheo, F Ament. Microanatomical localization of dopamine receptor protein immunoreactivity in the rat cerebellar cortex. Brain research. vol 854. issue 1-2. 2000-07-27. PMID:10784114. |
a faint d3 receptor protein immunoreactivity was also localized in purkinje neurons and to a lesser extent, in molecular and granular layers of cerebellar lobules 1-8. |
2000-07-27 |
2023-08-12 |
rat |