| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Simon Allard, Varin Gosein, A Claudio Cuello, A Ribeiro-da-Silv. Changes with aging in the dopaminergic and noradrenergic innervation of rat neocortex. Neurobiology of aging. vol 32. issue 12. 2012-08-08. PMID:20096955. |
although neuromodulation by dopamine and noradrenaline in the cortex is known to be important for proper cognitive function, little is known on how cortical noradrenergic and dopaminergic presynaptic boutons are affected in normal aging. |
2012-08-08 |
2023-08-12 |
rat |
| Simon Allard, Varin Gosein, A Claudio Cuello, A Ribeiro-da-Silv. Changes with aging in the dopaminergic and noradrenergic innervation of rat neocortex. Neurobiology of aging. vol 32. issue 12. 2012-08-08. PMID:20096955. |
following the behavioral characterization, the animals were sacrificed and the cortical tissue was processed for immunofluorescence using antibodies directed against tyrosine hydroxylase (th) and dopamine beta-hydroxylase (dbh) to detect and discriminate noradrenergic and dopaminergic varicosities. |
2012-08-08 |
2023-08-12 |
rat |
| Caroline C Smith, Robert W Green. CNS dopamine transmission mediated by noradrenergic innervation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 18. 2012-06-25. PMID:22553014. |
cns dopamine transmission mediated by noradrenergic innervation. |
2012-06-25 |
2023-08-12 |
mouse |
| Holly A Shill, Charles H Adler, Thomas G Beach, Lih-Fen Lue, John N Caviness, Marwan N Sabbagh, Lucia I Sue, Douglas G Walke. Brain biochemistry in autopsied patients with essential tremor. Movement disorders : official journal of the Movement Disorder Society. vol 27. issue 1. 2012-05-21. PMID:22038525. |
locus coeruleus dopamine beta-hydroxylase, a marker of noradrenergic neurons, was not significantly different between the essential tremor and control groups. |
2012-05-21 |
2023-08-12 |
human |
| Paola Devoto, Giovanna Flore, Pierluigi Saba, Roberto Cadeddu, Gian Luigi Gess. Disulfiram stimulates dopamine release from noradrenergic terminals and potentiates cocaine-induced dopamine release in the prefrontal cortex. Psychopharmacology. vol 219. issue 4. 2012-05-16. PMID:21863234. |
disulfiram stimulates dopamine release from noradrenergic terminals and potentiates cocaine-induced dopamine release in the prefrontal cortex. |
2012-05-16 |
2023-08-12 |
Not clear |
| David J Brooks, Nicola Paves. Imaging biomarkers in Parkinson's disease. Progress in neurobiology. vol 95. issue 4. 2012-04-09. PMID:21896306. |
while loss of putamen dopaminergic function leads to motor disability, lewy bodies not only target dopamine neurons but have also been observed in serotoninergic, noradrenergic, and cholinergic neurons. |
2012-04-09 |
2023-08-12 |
Not clear |
| Cristina Miguelez, Asier Aristieta, Maria Angela Cenci, Luisa Uged. The locus coeruleus is directly implicated in L-DOPA-induced dyskinesia in parkinsonian rats: an electrophysiological and behavioural study. PloS one. vol 6. issue 9. 2012-02-28. PMID:21931808. |
l-dopa-induced dyskinesia is attributed to a dysregulated dopamine transmission within the basal ganglia, but serotonergic and noradrenergic systems are believed to play an important modulatory role. |
2012-02-28 |
2023-08-12 |
rat |
| Y Fan, J Huang, M Duffourc, R L Kao, G A Ordway, R Huang, M-Y Zh. Transcription factor Phox2 upregulates expression of norepinephrine transporter and dopamine β-hydroxylase in adult rat brains. Neuroscience. vol 192. 2012-01-18. PMID:21763404. |
in the present study, recombinant lentiviral egfp-phox2a and -phox2b (vphox2a and vphox2b) were constructed to study the effects of phox2a/2b over-expression on dopamine β-hydroxylase (dbh) and norepinephrine transporter (net) levels in central noradrenergic neurons. |
2012-01-18 |
2023-08-12 |
rat |
| Tessa N Douma, Adam Kolarz, Ynte Postma, Berend Olivier, Lucianne Groenin. The amphetamine-chlordiazepoxide mixture, a pharmacological screen for mood stabilizers, does not enhance amphetamine-induced disruption of prepulse inhibition. Behavioural brain research. vol 225. issue 1. 2012-01-18. PMID:21820012. |
in addition, we combined chlordiazepoxide with the selective dopamine reuptake inhibitor gbr 12909 or the noradrenergic stimulant (-) ephedrine, and tested these alternative mixtures in locomotor activity and prepulse inhibition tests. |
2012-01-18 |
2023-08-12 |
Not clear |
| Jinwoo Park, Pavel Takmakov, R Mark Wightma. In vivo comparison of norepinephrine and dopamine release in rat brain by simultaneous measurements with fast-scan cyclic voltammetry. Journal of neurochemistry. vol 119. issue 5. 2012-01-09. PMID:21933188. |
simultaneous dopamine and norepinephrine release was evoked by electrical stimulation of a region where the ventral noradrenergic bundle, the pathway of noradrenergic neurons, courses through the ventral tegmental area/substantia nigra, the origin of dopaminergic cell bodies. |
2012-01-09 |
2023-08-12 |
rat |
| F Xavier Castellanos, M Teresa Acost. [Towards an understanding of the molecular mechanisms underlying the pharmacological treatments of attention deficit hyperactivity disorder]. Revista de neurologia. vol 52 Suppl 1. 2012-01-05. PMID:21365598. |
blockade of noradrenergic reuptake in the prefrontal cortex may also indirectly increase prefrontal dopamine levels, but there is also evidence that noradrenergic effects are mediated by alpha-2a noradrenergic receptors. |
2012-01-05 |
2023-08-12 |
Not clear |
| B A S Reyes, Charles Chavkin, E J Van Bockstael. Agonist-induced internalization of κ-opioid receptors in noradrenergic neurons of the rat locus coeruleus. Journal of chemical neuroanatomy. vol 40. issue 4. 2011-11-07. PMID:20884346. |
to determine whether agonist stimulation could induce adaptations in the expression of the noradrenergic synthesizing enzyme, dopamine beta hydroxylase (dβh), and κor expression, western blot analysis was used to compare expression levels of dβh and κor following u50,488 administration. |
2011-11-07 |
2023-08-12 |
human |
| Cristina Miguelez, Laura Grandoso, Luisa Uged. Locus coeruleus and dorsal raphe neuron activity and response to acute antidepressant administration in a rat model of Parkinson's disease. The international journal of neuropsychopharmacology. vol 14. issue 2. 2011-09-02. PMID:20426885. |
here, we investigated the effects of dopamine degeneration on the activity and response to antidepressants of locus coeruleus (lc) noradrenergic and dorsal raphe nucleus (drn) serotonergic neurons. |
2011-09-02 |
2023-08-12 |
rat |
| Anna Sadakierska-Chudy, Anna Haduch, Krystyna Gołembiowska, Władysława A Danie. Effects of low doses of intracerebroventricular 6-OHDA on the levels of monoaminergic neurotransmitters in rat brain structures. Pharmacological reports : PR. vol 62. issue 6. 2011-08-10. PMID:21273682. |
the results suggest that small doses of 6-ohda (25 or 50 μg per ventricle) could effectively damage the noradrenergic system in the hypothalamus without significant interfering with the dopamine level and with only a modest reduction in the serotonin concentration. |
2011-08-10 |
2023-08-12 |
rat |
| Nicola Pavese, Maria Rivero-Bosch, Stephanie J Lewis, Alan L Whone, David J Brook. Progression of monoaminergic dysfunction in Parkinson's disease: a longitudinal 18F-dopa PET study. NeuroImage. vol 56. issue 3. 2011-07-25. PMID:21396455. |
post-mortem and neuroimaging studies in parkinson's disease (pd) have shown involvement of the brain serotoninergic, noradrenergic and cholinergic pathways alongside the characteristic degeneration of nigrostriatal dopamine neurons. |
2011-07-25 |
2023-08-12 |
Not clear |
| Amy F T Arnste. Prefrontal cortical network connections: key site of vulnerability in stress and schizophrenia. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 29. issue 3. 2011-07-20. PMID:21345366. |
under optimal conditions, network inputs to pyramidal cells are strengthened by noradrenergic alpha-2a inhibition of camp-hcn channel signaling, and sculpted by dopamine d1-camp-hcn channel weakening of inappropriate inputs. |
2011-07-20 |
2023-08-12 |
Not clear |
| C Andrade, J George, T Josep. Br-16a does not interfere with alpha - 2 noradrenergic and dopamine postsynaptic receptor functioning. Indian journal of psychiatry. vol 35. issue 3. 2011-07-14. PMID:21743635. |
br-16a does not interfere with alpha - 2 noradrenergic and dopamine postsynaptic receptor functioning. |
2011-07-14 |
2023-08-12 |
rat |
| C Andrade, J George, T Josep. Br-16a does not interfere with alpha - 2 noradrenergic and dopamine postsynaptic receptor functioning. Indian journal of psychiatry. vol 35. issue 3. 2011-07-14. PMID:21743635. |
br-16a neither attenuated clonidine induced alpha-2 noradrenergic receptor-mediated hypomotility nor accentuated apomorphine-induced dopamine postsynaptic receptor-mediated hypermotility, suggesting that it does not interfere with alpha-2 noradrenergic and dopamine postsynaptic receptor functioning. |
2011-07-14 |
2023-08-12 |
rat |
| Michael J Pellegrino, Diana C Parrish, Richard E Zigmond, Beth A Habecke. Cytokines inhibit norepinephrine transporter expression by decreasing Hand2. Molecular and cellular neurosciences. vol 46. issue 3. 2011-06-16. PMID:21241805. |
the molecular basis for suppression of noradrenergic genes is not well understood, but previous studies implicated a reduction of phox2a in cytokine suppression of dopamine beta hydroxylase. |
2011-06-16 |
2023-08-12 |
Not clear |
| Benjamin Gronie. In vivo electrophysiological effects of methylphenidate in the prefrontal cortex: involvement of dopamine D1 and alpha 2 adrenergic receptors. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 21. issue 2. 2011-05-03. PMID:21146374. |
these results demonstrate the involvement of cortical dopamine d1 and noradrenergic alpha 2 receptors in the in vivo electrophysiological effects of mph on pfc neurones. |
2011-05-03 |
2023-08-12 |
rat |