| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michel M M Verheij, Alexander R Cool. Twenty years of dopamine research: individual differences in the response of accumbal dopamine to environmental and pharmacological challenges. European journal of pharmacology. vol 585. issue 2-3. 2008-07-18. PMID:18423601. |
data are summarised demonstrating that individual differences in accumbal dopamine release are due to individual differences in: the functional reactivity of the noradrenergic system, the accumbal concentration of vesicular monoamine transporters and tyrosine hydroxylase as well as in the quantal size of the presynaptic pools of dopamine. |
2008-07-18 |
2023-08-12 |
human |
| Paola Devoto, Giovanna Flore, Pierluigi Saba, M Paola Castelli, A Paola Piras, William Luesu, M Cristina Viaggi, M Grazia Ennas, Gian Luigi Gess. 6-Hydroxydopamine lesion in the ventral tegmental area fails to reduce extracellular dopamine in the cerebral cortex. Journal of neuroscience research. vol 86. issue 7. 2008-07-08. PMID:18189323. |
the results strongly support the hypothesis that the majority of extracellular dopamine in the cortex, unlike that in the nucleus accumbens, originates from noradrenergic terminals. |
2008-07-08 |
2023-08-12 |
rat |
| Mads Togsverd, Thomas M Werge, Laszlo B Tankó, Yu Z Bagger, Thomas Hansen, Gerong Qin, Claus Christiansen, Henrik B Rasmusse. Association of a dopamine beta-hydroxylase gene variant with depression in elderly women possibly reflecting noradrenergic dysfunction. Journal of affective disorders. vol 106. issue 1-2. 2008-05-14. PMID:17698206. |
association of a dopamine beta-hydroxylase gene variant with depression in elderly women possibly reflecting noradrenergic dysfunction. |
2008-05-14 |
2023-08-12 |
Not clear |
| Kevin B Freeman, Andrey Verendeev, Anthony L Rile. Noradrenergic antagonism enhances the conditioned aversive effects of cocaine. Pharmacology, biochemistry, and behavior. vol 88. issue 4. 2008-05-08. PMID:18045672. |
although limited evidence suggests a role for dopamine, there has yet to be a direct assessment of noradrenergic involvement. |
2008-05-08 |
2023-08-12 |
Not clear |
| David Weinshenker, Michela Ferrucci, Carla L Busceti, Francesca Biagioni, Gloria Lazzeri, L Cameron Liles, Paola Lenzi, Livia Pasquali, Luigi Murri, Antonio Paparelli, Francesco Forna. Genetic or pharmacological blockade of noradrenaline synthesis enhances the neurochemical, behavioral, and neurotoxic effects of methamphetamine. Journal of neurochemistry. vol 105. issue 2. 2008-05-06. PMID:18042179. |
n-(2-chloroethyl)-n-ethyl-2-bromobenzylamine (dsp-4) lesions of the locus coeruleus, the major brain noradrenergic nucleus, exacerbate the damage to nigrostriatal dopamine (da) terminals caused by the psychostimulant methamphetamine (meth). |
2008-05-06 |
2023-08-12 |
mouse |
| David Weinshenker, Michela Ferrucci, Carla L Busceti, Francesca Biagioni, Gloria Lazzeri, L Cameron Liles, Paola Lenzi, Livia Pasquali, Luigi Murri, Antonio Paparelli, Francesco Forna. Genetic or pharmacological blockade of noradrenaline synthesis enhances the neurochemical, behavioral, and neurotoxic effects of methamphetamine. Journal of neurochemistry. vol 105. issue 2. 2008-05-06. PMID:18042179. |
we addressed the specific role of na by comparing the effects of meth in mice with noradrenergic lesions (dsp-4) and those with intact noradrenergic terminals but specifically lacking na (genetic or acute pharmacological blockade of the na biosynthetic enzyme dopamine beta-hydroxylase; dbh). |
2008-05-06 |
2023-08-12 |
mouse |
| Rosa Andres, Luis A Herraez-Baranda, Jane Thompson, Sean Wyatt, Alun M Davie. Regulation of sympathetic neuron differentiation by endogenous nerve growth factor and neurotrophin-3. Neuroscience letters. vol 431. issue 3. 2008-05-02. PMID:18162309. |
despite the extensively documented ability of ngf to regulate the noradrenergic phenotype of sympathetic neurons, we found that tyrosine hydroxylase (th) and dopamine beta hydroxylase (dbetah) mrna levels were normal in ngf(-/-) embryos, but significantly reduced in nt3(-/-) embryos. |
2008-05-02 |
2023-08-12 |
mouse |
| Csaba Leranth, Tibor Hajsza. Extrinsic afferent systems to the dentate gyrus. Progress in brain research. vol 163. 2008-03-14. PMID:17765712. |
these systems are afferents originating from the medial septum/diagonal band of broca gabaergic and cholinergic neurons, neurochemically distinct types of neurons located in the supramammillary area, serotonergic fibers from the median raphe, noradrenergic afferents from the pontine nucleus, locus ceruleus, dopamine axons originating in the ventral tegmental area, and the commissural projection system. |
2008-03-14 |
2023-08-12 |
Not clear |
| Klaus B Fink, Manfred Göther. 5-HT receptor regulation of neurotransmitter release. Pharmacological reviews. vol 59. issue 4. 2008-03-06. PMID:18160701. |
this review focuses on 1) the function of presynaptic 5-hydroxytryptamine (5-ht) heteroreceptors on axon terminals of central cholinergic, dopaminergic, noradrenergic, or gabaergic neurons and 2) the role of gabaergic interneurons expressing 5-ht heteroreceptors in the regulation of acetylcholine, dopamine, or noradrenaline release. |
2008-03-06 |
2023-08-12 |
Not clear |
| Joel Nigg, Molly Nikolas, Karen Friderici, Leeyoung Park, Robert A Zucke. Genotype and neuropsychological response inhibition as resilience promoters for attention-deficit/hyperactivity disorder, oppositional defiant disorder, and conduct disorder under conditions of psychosocial adversity. Development and psychopathology. vol 19. issue 3. 2008-01-18. PMID:17705902. |
genotype was measured in sample 1, and a composite high risk genotype index was developed by summing presence of risk across markers on three genes expressed in prefrontal cortex: dopamine transporter, dopamine d4 receptor, and noradrenergic alpha-2 receptor. |
2008-01-18 |
2023-08-12 |
Not clear |
| F Arencibia-Albite, C Paladini, J T Williams, C A Jiménez-River. Noradrenergic modulation of the hyperpolarization-activated cation current (Ih) in dopamine neurons of the ventral tegmental area. Neuroscience. vol 149. issue 2. 2008-01-16. PMID:17884297. |
noradrenergic modulation of the hyperpolarization-activated cation current (ih) in dopamine neurons of the ventral tegmental area. |
2008-01-16 |
2023-08-12 |
rat |
| Kunio Kitahama, Michel Geffard, Silvia Araneda, Ryohachi Arai, Keiko Ogawa, Ikuko Nagatsu, Jean-Marc Pequigno. Localization of L-DOPA uptake and decarboxylating neuronal structures in the cat brain using dopamine immunohistochemistry. Brain research. vol 1167. 2007-12-14. PMID:17692830. |
l-dopa injection made it possible to detect dopamine immunoreactivity in presumptive serotonergic and noradrenergic cell bodies and axons. |
2007-12-14 |
2023-08-12 |
cat |
| Francesco Fornai, Adolfo Bandettini di Poggio, Antonio Pellegrini, Stefano Ruggieri, Antonio Paparell. Noradrenaline in Parkinson's disease: from disease progression to current therapeutics. Current medicinal chemistry. vol 14. issue 22. 2007-12-03. PMID:17896981. |
novel data also show that the loss of noradrenergic innervation facilitates the onset of dyskinesia occurring in parkinsonian patients during dopamine replacement therapy. |
2007-12-03 |
2023-08-12 |
Not clear |
| Francesco Fornai, Adolfo Bandettini di Poggio, Antonio Pellegrini, Stefano Ruggieri, Antonio Paparell. Noradrenaline in Parkinson's disease: from disease progression to current therapeutics. Current medicinal chemistry. vol 14. issue 22. 2007-12-03. PMID:17896981. |
this evidence is discussed in light of novel reports showing the deleterious effects produced by the noradrenergic deficit on the survival of nigral dopamine neurons. |
2007-12-03 |
2023-08-12 |
Not clear |
| David Nutt, Koen Demyttenaere, Zoltan Janka, Trond Aarre, Michel Bourin, Pier Luigi Canonico, Jose Luis Carrasco, Steven Stah. The other face of depression, reduced positive affect: the role of catecholamines in causation and cure. Journal of psychopharmacology (Oxford, England). vol 21. issue 5. 2007-10-04. PMID:17050654. |
dopaminergic and noradrenergic agents, including the dual acting norepinephrine and dopamine re-uptake inhibitors, have demonstrated antidepressant activity in the absence of serotonergic function, showing similar efficacy to both tricyclic and serotonin re-uptake inhibitor antidepressants. |
2007-10-04 |
2023-08-12 |
Not clear |
| Yuka Morikawa, Fabien D'Autréaux, Michael D Gershon, Peter Cserjes. Hand2 determines the noradrenergic phenotype in the mouse sympathetic nervous system. Developmental biology. vol 307. issue 1. 2007-09-10. PMID:17531968. |
to determine whether hand2 regulates noradrenergic differentiation, the levels of the norepinephrine biosynthetic enzymes, tyrosine hydroxylase (th) and dopamine beta-hydroxylase (dbh) was examined. |
2007-09-10 |
2023-08-12 |
mouse |
| David Weinshenker, Jason P Schroede. There and back again: a tale of norepinephrine and drug addiction. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 7. 2007-08-31. PMID:17164822. |
however, reward experiments from the mid-1970s that could distinguish between the noradrenergic and dopaminergic systems resulted in the prevailing view that dopamine (da) was the primary 'reward transmitter' (a belief holding some sway still today), thereby pushing ne into the background. |
2007-08-31 |
2023-08-12 |
mouse |
| James M Swanso. Role of executive function in ADHD. The Journal of clinical psychiatry. vol 64 Suppl 14. 2007-08-27. PMID:14658934. |
stimulants primarily have dopaminergic and noradrenergic mechanisms of action, with blockade at the dopamine transporter reducing reuptake, resulting in an increase in these neurotransmitters at the synapse. |
2007-08-27 |
2023-08-12 |
Not clear |
| Shoko Hirano, Shigeo Miyata, Kenji Onodera, Junzo Kame. Involvement of dopamine D1 receptors and alpha1-adrenoceptors in the antidepressant-like effect of chlorpheniramine in the mouse tail suspension test. European journal of pharmacology. vol 562. issue 1-2. 2007-06-13. PMID:17328889. |
in this study, we examined the involvement of dopaminergic (dopamine d(1) and dopamine d(2) receptors), noradrenergic (alpha(1)- and beta-adrenoceptors) and serotonergic (5-ht(1a) and 5-ht(2) receptors) receptors in the antidepressant-like effect of chlorpheniramine in the mouse tail suspension test. |
2007-06-13 |
2023-08-12 |
mouse |
| Brid Nicniocaill, Alain Gratto. Medial prefrontal cortical alpha1 adrenoreceptor modulation of the nucleus accumbens dopamine response to stress in Long-Evans rats. Psychopharmacology. vol 191. issue 3. 2007-06-12. PMID:17294052. |
the medial prefrontal cortex (pfc) receives stress-sensitive dopamine (da) and noradrenergic (ne) projections from the ventral tegmental area and locus coeruleus, respectively, and evidence from various sources point to a complex functional interaction between these two systems. |
2007-06-12 |
2023-08-12 |
rat |