| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J L Rose, A S Hamlin, C J Scot. Sex differences in the expression of estrogen receptor alpha within noradrenergic neurons in the sheep brain stem. Domestic animal endocrinology. vol 49. 2015-05-15. PMID:25010022. |
to determine the distribution of erα, we used double-label fluorescence immunohistochemistry for dopamine β-hydroxylase, as a marker for noradrenergic and adrenergic cells, and erα. |
2015-05-15 |
2023-08-13 |
Not clear |
| Sylvia Navailles, Léa Milan, Hanane Khalki, Giuseppe Di Giovanni, Mélanie Lagière, Philippe De Deurwaerdèr. Noradrenergic terminals regulate L-DOPA-derived dopamine extracellular levels in a region-dependent manner in Parkinsonian rats. CNS neuroscience & therapeutics. vol 20. issue 7. 2015-02-06. PMID:24775184. |
noradrenergic terminals regulate l-dopa-derived dopamine extracellular levels in a region-dependent manner in parkinsonian rats. |
2015-02-06 |
2023-08-13 |
rat |
| Ingrid H C H M Philippens, Marloes J A Joosen, Abdellah Ahnaou, Ignacio Andres, Wilhelmus Pim H I M Drinkenbur. Anti-Parkinson effects of a selective alpha2C-adrenoceptor antagonist in the MPTP marmoset model. Behavioural brain research. vol 269. 2015-01-15. PMID:24769173. |
the noradrenergic system plays an important role in the facilitation or maintenance of the activity of the nigrostriatal dopamine pathways. |
2015-01-15 |
2023-08-13 |
monkey |
| Susana Marques de Sousa, João Massan. Motor complications in Parkinson's disease: a comprehensive review of emergent management strategies. CNS & neurological disorders drug targets. vol 12. issue 7. 2014-11-12. PMID:23844692. |
glutamatergic, serotonergic, noradrenergic, adenosinergic and cholinergic systems), gene therapy for delivering neurotrophic factors or critical enzymes for dopamine synthesis, and cell therapy. |
2014-11-12 |
2023-08-12 |
Not clear |
| Alessandra Bonito-Oliva, Débora Masini, Gilberto Fison. A mouse model of non-motor symptoms in Parkinson's disease: focus on pharmacological interventions targeting affective dysfunctions. Frontiers in behavioral neuroscience. vol 8. 2014-09-15. PMID:25221486. |
based on these findings we propose that the anti-depressive and anxiolytic action of reboxetine is mediated by promoting dopamine transmission through blockade of dopamine uptake from residual noradrenergic terminals. |
2014-09-15 |
2023-08-13 |
mouse |
| Nicholas J Malecek, Russell A Poldrac. Beyond dopamine: the noradrenergic system and mental effort. The Behavioral and brain sciences. vol 36. issue 6. 2014-09-08. PMID:24304796. |
beyond dopamine: the noradrenergic system and mental effort. |
2014-09-08 |
2023-08-12 |
Not clear |
| Yan Wang, Phillip R Musich, Moises A Serrano, Yue Zou, Jia Zhang, Meng-Yang Zh. Effects of DSP4 on the noradrenergic phenotypes and its potential molecular mechanisms in SH-SY5Y cells. Neurotoxicity research. vol 25. issue 2. 2014-09-07. PMID:23996700. |
dopamine β-hydroxylase (dbh) and norepinephrine (ne) transporter (net) are the noradrenergic phenotypes for their functional importance to noradrenergic neurons. |
2014-09-07 |
2023-08-12 |
Not clear |
| Debra A Cooper, Heather L Kimmel, Daniel F Manvich, Karl T Schmidt, David Weinshenker, Leonard L Howel. Effects of pharmacologic dopamine β-hydroxylase inhibition on cocaine-induced reinstatement and dopamine neurochemistry in squirrel monkeys. The Journal of pharmacology and experimental therapeutics. vol 350. issue 1. 2014-08-26. PMID:24817036. |
one of many biochemical actions of disulfiram is inhibition of dopamine β-hydroxylase (dbh), the enzyme that converts dopamine (da) to norepinephrine (ne) in noradrenergic neurons. |
2014-08-26 |
2023-08-13 |
rat |
| T A Slotkin, W L Whitmore, L Lerea, R J Slepetis, S J Weigel, P A Trepanier, F J Seidle. Role of ornithine decarboxylase and the polyamines in nervous system development: Short-term postnatal administration of α-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 1. issue 1. 2014-06-02. PMID:24875600. |
development of the adrenal medulla, a peripheral catecholaminergic tissue which displays approximately the same developmental profile as do sympathetic neurons but which does not develop axonal projections, was not slowed by dfmo treatment; similarly, central noradrenergic and dopaminergic neurons, which undergo the majority of axonal outgrowth and synaptogenesis during the second to third postnatal week (just after the period in which polyamines returned to control levels), developed normally as assessed by measurements of transmitter levels, tyrosine hydroxylase activity and synaptosomal uptake of [(3)h]norepinephrine or [(3)h]dopamine. |
2014-06-02 |
2023-08-13 |
rat |
| Julie G Hensler, Francesc Artigas, Analía Bortolozzi, Lynette C Daws, Philippe De Deurwaerdère, Léa Milan, Sylvia Navailles, Wouter Koe. Catecholamine/Serotonin interactions: systems thinking for brain function and disease. Advances in pharmacology (San Diego, Calif.). vol 68. 2014-05-29. PMID:24054145. |
however, the ectopic release of dopamine (da) from serotonin neurons and the clearance of extracellular da by the norepinephrine transporter in areas enriched with noradrenergic terminals contribute to extracellular da produced by l-dopa and offer opportunities to improve l-dopa therapy. |
2014-05-29 |
2023-08-12 |
Not clear |
| Wojciech Rocznia. Assessment of dopamine (DA) synthesis rate in selected parts of the rat brain with central noradrenergic lesion after administration of 5-HT3 receptor ligands. Postepy higieny i medycyny doswiadczalnej (Online). vol 67. 2014-04-29. PMID:24018429. |
assessment of dopamine (da) synthesis rate in selected parts of the rat brain with central noradrenergic lesion after administration of 5-ht3 receptor ligands. |
2014-04-29 |
2023-08-12 |
rat |
| Wojciech Rocznia. Assessment of dopamine (DA) synthesis rate in selected parts of the rat brain with central noradrenergic lesion after administration of 5-HT3 receptor ligands. Postepy higieny i medycyny doswiadczalnej (Online). vol 67. 2014-04-29. PMID:24018429. |
the study objective was to determine the effect of central noradrenergic system lesions performed in the early extrafetal life period on dopamine synthesis in the rat brain. |
2014-04-29 |
2023-08-12 |
rat |
| Adam Przybyłkowski, Grażyna Gromadzka, Adriana Wawer, Ewa Bulska, Katarzyna Jabłonka-Salach, Tomasz Grygorowicz, Anna Schnejder-Pachołek, Andrzej Członkowsk. Neurochemical and behavioral characteristics of toxic milk mice: an animal model of Wilson's disease. Neurochemical research. vol 38. issue 10. 2014-03-28. PMID:23877404. |
in order to detect neuronal loss, expression of enzymes specific for dopaminergic [tyrosine hydroxylase (th)], noradrenergic (dopamine beta-hydroxylase) and serotoninergic [tryptophan hydroxylase (tph)] neurons was analyzed by western blot. |
2014-03-28 |
2023-08-12 |
mouse |
| Daniel F Manvich, Lauren M DePoy, David Weinshenke. Dopamine β-hydroxylase inhibitors enhance the discriminative stimulus effects of cocaine in rats. The Journal of pharmacology and experimental therapeutics. vol 347. issue 3. 2014-01-23. PMID:24068832. |
inhibitors of dopamine β-hydroxylase (dbh), the enzyme that converts dopamine (da) to norepinephrine (ne) in noradrenergic cells, have shown promise for the treatment of cocaine abuse disorders. |
2014-01-23 |
2023-08-12 |
human |
| Changsu Han, Sheng-Min Wang, Masaki Kato, Soo-Jung Lee, Ashwin A Patkar, Prakash S Masand, Chi-Un Pa. Second-generation antipsychotics in the treatment of major depressive disorder: current evidence. Expert review of neurotherapeutics. vol 13. issue 7. 2013-12-31. PMID:23898855. |
to overcome such a serious mental disorder, we currently have a number of different classes of antidepressants, such as selective serotonin reuptake inhibitors, serotonin-norepinephrine reuptake inhibitors, noradrenergic and specific serotonin receptor antagonists, dopamine and norepinephrine reuptake inhibitors, along with newly introduced antidepressants (e.g., vilazodone and agomelatine). |
2013-12-31 |
2023-08-12 |
Not clear |
| b' Nadia Schendzielorz, Juha-Pekka Oinas, Timo T My\\xc3\\xb6h\\xc3\\xa4nen, Ilkka Reenil\\xc3\\xa4, Atso Raasmaja, Pekka T M\\xc3\\xa4nnist\\xc3\\xb. Catechol-O-methyltransferase (COMT) protein expression and activity after dopaminergic and noradrenergic lesions of the rat brain. PloS one. vol 8. issue 4. 2013-11-14. PMID:23613844.' |
destruction of dopaminergic and noradrenergic neurons was assessed by measuring the dopamine and noradrenaline content in the projection areas of these neurons. |
2013-11-14 |
2023-08-12 |
rat |
| Yan Fan, Ping Chen, Ying Li, Meng-Yang Zh. Effects of chronic social defeat on expression of dopamine β-hydroxylase in rat brains. Synapse (New York, N.Y.). vol 67. issue 6. 2013-10-29. PMID:23389997. |
however, there are far few reports regarding effects of stress on the expression of dopamine β-hydroxylase, a hallmark enzyme of the noradrenergic neuron. |
2013-10-29 |
2023-08-12 |
rat |
| Jennifer M Wright, May R S Dobosiewicz, Paul B S Clark. The role of dopaminergic transmission through D1-like and D2-like receptors in amphetamine-induced rat ultrasonic vocalizations. Psychopharmacology. vol 225. issue 4. 2013-10-17. PMID:23052567. |
systemic amphetamine (amph) administration increases the rate of 50-khz ultrasonic vocalizations (usvs) in adult rats and preferentially enhances the 'trill' subtype; these effects of amph critically depend on noradrenergic transmission, but the possible contributions of dopamine are unclear. |
2013-10-17 |
2023-08-12 |
rat |
| Yoon-Sang Oh, Joong-Seok Kim, Yong-An Chung, Ie Ryung You, Dong-Won Yang, Sung-Woo Chung, Jeong-Wook Park, Yeong-In Kim, Kwang-Soo Le. Orthostatic hypotension, non-dipping and striatal dopamine in Parkinson disease. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 34. issue 4. 2013-09-26. PMID:22893360. |
these results suggest that sympathetic noradrenergic dysfunctions in pd are independent of striatal dopamine transporter depletion. |
2013-09-26 |
2023-08-12 |
Not clear |
| Mercè Masana, Noemí Santana, Francesc Artigas, Analía Bortolozz. Dopamine neurotransmission and atypical antipsychotics in prefrontal cortex: a critical review. Current topics in medicinal chemistry. vol 12. issue 21. 2013-08-30. PMID:23279176. |
these targets include dopamine and serotonin receptors in the prefrontal cortex, as well as elements of the noradrenergic system. |
2013-08-30 |
2023-08-12 |
Not clear |