| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ming-Hui Sun, Kuan-Jen Chen, Chi-Chin Sun, Rong-Kung Tsa. Protective Effect of Pioglitazone on Retinal Ganglion Cells in an Experimental Mouse Model of Ischemic Optic Neuropathy. International journal of molecular sciences. vol 24. issue 1. 2023-01-08. PMID:36613856. |
furthermore, microglial cell infiltration in the retina (group 1: 2.0 ± 2.6 cells/field; group 2: 15.6 ± 3.5 cells/field; and group 3: 14.8 ± 7.5 cells/field) and retinal thinning (group 1: 6.7 ± 5.7 μm; group 2: 12.8 ± 6.1 μm; and group 3: 15.8 ± 5.8 μm) were also lower in group 1 than in the other two groups. |
2023-01-08 |
2023-08-14 |
mouse |
| Kjell Johansson, Camilla Mohli. Microglia in Cultured Porcine Retina: Qualitative Immunohistochemical Analyses of Reactive Microglia in the Outer Retina. International journal of molecular sciences. vol 24. issue 1. 2023-01-08. PMID:36614320. |
microglia in cultured porcine retina: qualitative immunohistochemical analyses of reactive microglia in the outer retina. |
2023-01-08 |
2023-08-14 |
Not clear |
| Kjell Johansson, Camilla Mohli. Microglia in Cultured Porcine Retina: Qualitative Immunohistochemical Analyses of Reactive Microglia in the Outer Retina. International journal of molecular sciences. vol 24. issue 1. 2023-01-08. PMID:36614320. |
in this immunohistochemical study, we have begun to analyze the transition of subsets of reactive microglia which are known to localize close to the outer plexiform layer (opl) in degenerating in vivo and in vitro retina. |
2023-01-08 |
2023-08-14 |
Not clear |
| Elisa Murenu, Maximilian-Joachim Gerhardt, Martin Biel, Stylianos Michalaki. More than meets the eye: The role of microglia in healthy and diseased retina. Frontiers in immunology. vol 13. 2022-12-16. PMID:36524119. |
more than meets the eye: the role of microglia in healthy and diseased retina. |
2022-12-16 |
2023-08-14 |
Not clear |
| Elisa Murenu, Maximilian-Joachim Gerhardt, Martin Biel, Stylianos Michalaki. More than meets the eye: The role of microglia in healthy and diseased retina. Frontiers in immunology. vol 13. 2022-12-16. PMID:36524119. |
while most knowledge about microglia comes from brain studies, some mechanisms have been confirmed for microglia cells in the retina, the light-sensing compartment of the eye responsible for initial processing of visual information. |
2022-12-16 |
2023-08-14 |
Not clear |
| Elisa Murenu, Maximilian-Joachim Gerhardt, Martin Biel, Stylianos Michalaki. More than meets the eye: The role of microglia in healthy and diseased retina. Frontiers in immunology. vol 13. 2022-12-16. PMID:36524119. |
however, several key pieces of this puzzle are still unaccounted for, as the characterization of retinal microglia has long been hindered by the reduced population size within the retina as well as the previous lack of technologies enabling single-cell analyses. |
2022-12-16 |
2023-08-14 |
Not clear |
| Elisa Murenu, Maximilian-Joachim Gerhardt, Martin Biel, Stylianos Michalaki. More than meets the eye: The role of microglia in healthy and diseased retina. Frontiers in immunology. vol 13. 2022-12-16. PMID:36524119. |
thus, studying the roles and signatures adopted specifically by microglia in the retina has become increasingly important. |
2022-12-16 |
2023-08-14 |
Not clear |
| Kaira A Church, Derek Rodriguez, Difernando Vanegas, Irene L Gutierrez, Sandra M Cardona, José L M Madrigal, Tejbeer Kaur, Astrid E Cardon. Models of microglia depletion and replenishment elicit protective effects to alleviate vascular and neuronal damage in the diabetic murine retina. Journal of neuroinflammation. vol 19. issue 1. 2022-12-14. PMID:36517889. |
models of microglia depletion and replenishment elicit protective effects to alleviate vascular and neuronal damage in the diabetic murine retina. |
2022-12-14 |
2023-08-14 |
Not clear |
| Kaira A Church, Derek Rodriguez, Difernando Vanegas, Irene L Gutierrez, Sandra M Cardona, José L M Madrigal, Tejbeer Kaur, Astrid E Cardon. Models of microglia depletion and replenishment elicit protective effects to alleviate vascular and neuronal damage in the diabetic murine retina. Journal of neuroinflammation. vol 19. issue 1. 2022-12-14. PMID:36517889. |
microglia, the resident phagocytes of the retina, are believed to influence the development of retinopathy, but their exact contributions to vascular integrity and neuronal loss are unknown. |
2022-12-14 |
2023-08-14 |
Not clear |
| Kaira A Church, Derek Rodriguez, Difernando Vanegas, Irene L Gutierrez, Sandra M Cardona, José L M Madrigal, Tejbeer Kaur, Astrid E Cardon. Models of microglia depletion and replenishment elicit protective effects to alleviate vascular and neuronal damage in the diabetic murine retina. Journal of neuroinflammation. vol 19. issue 1. 2022-12-14. PMID:36517889. |
therefore, utilizing two models of microglia depletion, we aimed to deplete and repopulate microglia to clarify the contribution of microglia to neuronal loss and vascular damage in the diabetic retina in an stz-induced model of hyperglycemia. |
2022-12-14 |
2023-08-14 |
Not clear |
| Siva Prasad Panda, P Hemachandra Reddy, Uma Sankar Gorla, Dsnbk Prasant. Neuroinflammation and neovascularization in diabetic eye diseases (DEDs): identification of potential pharmacotherapeutic targets. Molecular biology reports. 2022-12-13. PMID:36513866. |
microglia in the retina of the optic nerve head are responsible for causing inflammation, discomfort, and neurodegeneration. |
2022-12-13 |
2023-08-14 |
Not clear |
| Sienna S Drake, Marc Charabati, Tristan Simas, Yu Kang T Xu, Etienne J P Maes, Shan Shan Shi, Jack Antel, Alexandre Prat, Barbara Morquette, Alyson E Fournie. 3-Dimensional Immunostaining and Automated Deep-Learning Based Analysis of Nerve Degeneration. International journal of molecular sciences. vol 23. issue 23. 2022-12-11. PMID:36499143. |
it contains axons from the retinal ganglion cells (rgcs) that reside in the retina, myelin forming oligodendrocytes and resident microglia and astrocytes. |
2022-12-11 |
2023-08-14 |
mouse |
| Bingqiao Shen, Huan Yu, Mingui Zhang, Junjue Chen, Yang Zhang, Shushu Xu, Ruiqi Han, Shouyue Huang, Ping Huang, Yisheng Zhon. Establishment of a minimally invasive distal traumatic optic neuropathy model in mice to investigate cascade reactions of retinal glial cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 37. issue 1. 2022-12-05. PMID:36468758. |
immunofluorescence, western blotting, qpcr experiments were conducted to investigate the loss of rgcs and activation or inactivation of microglia, astrocytes and müller glial cells in the retina from the first week to the fourth week after modeling. |
2022-12-05 |
2023-08-14 |
mouse |
| Paul-Alexandre Déchelle-Marquet, Xavier Guillonneau, Florian Sennlaub, Cécile Delarass. P2X7-dependent immune pathways in retinal diseases. Neuropharmacology. 2022-11-13. PMID:36372269. |
in the eye, p2x7 is expressed by resident microglia and immune cells that infiltrate the retina in disease such as age-related macular degeneration (amd), a degenerative retinal disease, and uveitis, an inflammatory eye disease. |
2022-11-13 |
2023-08-14 |
Not clear |
| Bright Asare-Bediako, Yvonne Adu-Agyeiwaah, Antonio Abad, Sergio Li Calzi, Jason L Floyd, Ram Prasad, Mariana DuPont, Richmond Asare-Bediako, Xose R Bustelo, Maria B Gran. Hematopoietic Cells Influence Vascular Development in the Retina. Cells. vol 11. issue 20. 2022-10-27. PMID:36291075. |
by flow cytometry and immunohistochemistry, we show that hematopoietic cells are present in the retina as early as p0, and include microglia, monocytes and macs. |
2022-10-27 |
2023-08-14 |
Not clear |
| Ziyi Zhou, Yutong Jing, Yali Niu, Tianfang Chang, Jiaxing Sun, Changmei Guo, Yusheng Wang, Guorui Do. Distinguished Functions of Microglia in the Two Stages of Oxygen-Induced Retinopathy: A Novel Target in the Treatment of Ischemic Retinopathy. Life (Basel, Switzerland). vol 12. issue 10. 2022-10-27. PMID:36295111. |
microglia is the resident immune cell in the retina, playing the role of immune surveillance in a traditional concept. |
2022-10-27 |
2023-08-14 |
Not clear |
| Yasuhiko Sato, Shoko Saito, Makiko Nakayama, Sunao Sugita, Akihiko Kudo, Hiroshi Kein. Genetic Ablation of Nrf2 Exacerbates Neuroinflammation in Ocular Autoimmunity. International journal of molecular sciences. vol 23. issue 19. 2022-10-14. PMID:36233013. |
gfap positive cells (astrocytes) and iba-1 positive cells (microglia cells) in the retina were more numerous in nrf2 ko mice compared to wt mice. |
2022-10-14 |
2023-08-14 |
mouse |
| Yu Huan, Xiu-Quan Wu, Tao Chen, Ya-Nan Dou, Bo Jia, Xin He, Dong-Yu Wei, Zhou Fei, Fei Fe. Necroptosis plays a crucial role in the exacerbation of retinal injury after blunt ocular trauma. Neural regeneration research. vol 18. issue 4. 2022-10-07. PMID:36204864. |
additionally, blunt ocular trauma induced nerve regeneration and müller glial hyperplasia; it also resulted in the recruitment of microglia to the retina and polarization of those microglia to the m1 phenotype. |
2022-10-07 |
2023-08-14 |
Not clear |
| Zizhu Tan, Yinjie Guo, Maleeka Shrestha, Daniel Sun, Meredith Gregory-Ksander, Tatjana C Jakob. Microglia depletion exacerbates retinal ganglion cell loss in a mouse model of glaucoma. Experimental eye research. 2022-10-07. PMID:36206859. |
plx5622 efficiently depleted microglia in the retina and the optic nerve head, but about 20% of microglia persisted in the myelinated optic nerve proper even after prolonged exposure to the drug. |
2022-10-07 |
2023-08-14 |
mouse |
| Qinyuan Alis Xu, Pierre Boerkoel, Veronica Hirsch-Reinshagen, Ian R Mackenzie, Ging-Yuek Robin Hsiung, Geoffrey Charm, Elliott F To, Alice Q Liu, Katerina Schwab, Kailun Jiang, Marinko Sarunic, Mirza Faisal Beg, Wellington Pham, Jing Cui, Eleanor To, Sieun Lee, Joanne A Matsubar. Müller cell degeneration and microglial dysfunction in the Alzheimer's retina. Acta neuropathologica communications. vol 10. issue 1. 2022-10-05. PMID:36199154. |
this study focused on the relationship of aβ with macroglia and microglia, as these glial cells are hypothesized to play important roles in homeostasis and clearance of aβ in the ad retina. |
2022-10-05 |
2023-08-14 |
Not clear |