| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fenge Li, Danye Jiang, Melanie A Samue. Microglia in the developing retina. Neural development. vol 14. issue 1. 2020-09-18. PMID:31888774. |
we then review the models and methods used for the study of these cells and discuss emerging data that link retina microglia to the genesis and survival of particular retina cell subtypes. |
2020-09-18 |
2023-08-13 |
Not clear |
| Indrajeetsinh Rana, Varaporn Suphapimol, Jack R Jerome, Dean M Talia, Devy Deliyanti, Jennifer L Wilkinson-Berk. Angiotensin II and aldosterone activate retinal microglia. Experimental eye research. vol 191. 2020-07-24. PMID:31884019. |
we hypothesized that key effectors of the renin-angiotensin aldosterone system, angiotensin ii (ang ii) and aldosterone, increase the density of microglia in the retina and stimulate their production of reactive oxygen species (ros) as well as pro-angiogenic and pro-inflammatory factors. |
2020-07-24 |
2023-08-13 |
rat |
| Sarah R Anderson, Jacqueline M Roberts, Jianmin Zhang, Michael R Steele, Cesar O Romero, Alejandra Bosco, Monica L Vette. Developmental Apoptosis Promotes a Disease-Related Gene Signature and Independence from CSF1R Signaling in Retinal Microglia. Cell reports. vol 27. issue 7. 2020-07-01. PMID:31091440. |
we profiled microglia of a discrete developing cns region, the murine retina. |
2020-07-01 |
2023-08-13 |
Not clear |
| Gilad Allon, Irit Mann, Lital Remez, Elisabeth Sehn, Leah Rizel, Mariela J Nevet, Ido Perlman, Uwe Wolfrum, Tamar Ben-Yose. PRCD is concentrated at the base of photoreceptor outer segments and is involved in outer segment disc formation. Human molecular genetics. vol 28. issue 24. 2020-06-23. PMID:31628458. |
electron microscopy revealed severe damage to photoreceptor outer segments, which is associated with immigration of microglia cells to the prcd-knockout retina and accumulation of vesicles in the inter-photoreceptor space. |
2020-06-23 |
2023-08-13 |
mouse |
| Lixia Luo, Jin Yang, Yumin Oh, Matthew J Hartsock, Shiyu Xia, Yoo-Chun Kim, Zheng Ding, Tuo Meng, Charles G Eberhart, Laura M Ensign, Jennifer E Thorne, Walter J Stark, Elia J Duh, Qingguo Xu, Justin Hane. Controlled release of corticosteroid with biodegradable nanoparticles for treating experimental autoimmune uveitis. Journal of controlled release : official journal of the Controlled Release Society. vol 296. 2020-05-22. PMID:30660629. |
furthermore, sct dsp-zn-np significantly reduced microglia cell density in the retina, a hallmark of eau in rats. |
2020-05-22 |
2023-08-13 |
rat |
| Petra Schwarzer, Despina Kokona, Andreas Ebneter, Martin S Zinkernage. Effect of Inhibition of Colony-Stimulating Factor 1 Receptor on Choroidal Neovascularization in Mice. The American journal of pathology. vol 190. issue 2. 2020-05-04. PMID:31783006. |
a 98% reduction of retinal microglia cells was observed in the retina 1 week after initiation of plx5622 treatment, preventing accumulation of macrophages within the laser site and leading to a reduction of leukocytes within the choroid after cnv induction. |
2020-05-04 |
2023-08-13 |
mouse |
| Tejasvi Dudiki, Julia Meller, Gautam Mahajan, Huan Liu, Irina Zhevlakova, Samantha Stefl, Conner Witherow, Eugene Podrez, Chandrasekhar R Kothapalli, Tatiana V Byzov. Microglia control vascular architecture via a TGFβ1 dependent paracrine mechanism linked to tissue mechanics. Nature communications. vol 11. issue 1. 2020-05-04. PMID:32080187. |
here, we report that during colonization of the retina, microglia contacts the deep layer of high stiffness, which coincides with microglial bipolarization, reduction in tgfβ1 signaling and termination of vascular growth. |
2020-05-04 |
2023-08-13 |
Not clear |
| James F Striebel, Brent Race, Katie Williams, James A Carroll, Mikael Klingeborn, Bruce Chesebr. Microglia are not required for prion-induced retinal photoreceptor degeneration. Acta neuropathologica communications. vol 7. issue 1. 2020-03-30. PMID:30909963. |
administration of plx5622 was highly effective at ablating microglia in retina. |
2020-03-30 |
2023-08-13 |
mouse |
| Yoko Okunuki, Ryo Mukai, Takeshi Nakao, Steven J Tabor, Oleg Butovsky, Reza Dana, Bruce R Ksander, Kip M Conno. Retinal microglia initiate neuroinflammation in ocular autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 20. 2020-03-30. PMID:31023885. |
in the absence of microglia, uveitis does not develop, since leukocytes cannot gain entry through the blood-retinal barrier, illustrating that microglia play a critical role in regulating infiltration of inflammatory cells into the retina. |
2020-03-30 |
2023-08-13 |
Not clear |
| Sean K Wang, Yunlu Xue, Parimal Rana, Christin M Hong, Constance L Cepk. Soluble CX3CL1 gene therapy improves cone survival and function in mouse models of retinitis pigmentosa. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 20. 2020-03-30. PMID:31036641. |
aav8-scx3cl1 did not affect rod survival, microglia localization, or inflammatory cytokine levels in the retina. |
2020-03-30 |
2023-08-13 |
mouse |
| Eric B Miller, Pengfei Zhang, Karli Ching, Edward N Pugh, Marie E Burn. In vivo imaging reveals transient microglia recruitment and functional recovery of photoreceptor signaling after injury. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 33. 2020-03-25. PMID:31350349. |
here, we have used in vivo high-resolution optical coherence tomography (oct) and scanning laser ophthalmoscopy with and without adaptive optics to quantify the 3d distribution and dynamics of microglia in the living retina before and after local damage to photoreceptors. |
2020-03-25 |
2023-08-13 |
Not clear |
| Eric B Miller, Pengfei Zhang, Karli Ching, Edward N Pugh, Marie E Burn. In vivo imaging reveals transient microglia recruitment and functional recovery of photoreceptor signaling after injury. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 33. 2020-03-25. PMID:31350349. |
following photoreceptor injury, microglia migrated both laterally and vertically through the retina over many hours, forming a tight cluster within the area of visible damage that resolved over 2 wk. |
2020-03-25 |
2023-08-13 |
Not clear |
| Sarah R Anderson, Jianmin Zhang, Michael R Steele, Cesar O Romero, Amanda G Kautzman, Dorothy P Schafer, Monica L Vette. Complement Targets Newborn Retinal Ganglion Cells for Phagocytic Elimination by Microglia. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 11. 2020-03-16. PMID:30647151. |
here, we investigate microglia function during embryonic mouse retina development, where only microglia, progenitors, and neurons are present. |
2020-03-16 |
2023-08-13 |
mouse |
| Rayne R Lim, Dean P Hainsworth, Rajiv R Mohan, Shyam S Chaurasi. Characterization of a functionally active primary microglial cell culture from the pig retina. Experimental eye research. vol 185. 2020-02-28. PMID:31103710. |
characterization of a functionally active primary microglial cell culture from the pig retina. |
2020-02-28 |
2023-08-13 |
human |
| Samuel M Peterson, Trevor J McGill, Teresa Puthussery, Jonathan Stoddard, Lauren Renner, Anne D Lewis, Lois M A Colgin, Jacqueline Gayet, Xiaojie Wang, Kamm Prongay, Cassandra Cullin, Brandy L Dozier, Betsy Ferguson, Martha Neuringe. Bardet-Biedl Syndrome in rhesus macaques: A nonhuman primate model of retinitis pigmentosa. Experimental eye research. vol 189. 2020-02-28. PMID:31589838. |
histological assessments in the 4- and 6-year-old cases confirmed profound loss of photoreceptors and inner retinal neurons across the posterior retina, with dramatic thinning and disorganization of all cell layers, abundant microglia, absent or displaced rpe cells, and significant gliosis in the subretinal space. |
2020-02-28 |
2023-08-13 |
human |
| A Tisi, M Passacantando, M Ciancaglini, R Maccaron. Nanoceria neuroprotective effects in the light-damaged retina: A focus on retinal function and microglia activation. Experimental eye research. vol 188. 2020-02-21. PMID:31520599. |
nanoceria neuroprotective effects in the light-damaged retina: a focus on retinal function and microglia activation. |
2020-02-21 |
2023-08-13 |
human |
| A Tisi, M Passacantando, M Ciancaglini, R Maccaron. Nanoceria neuroprotective effects in the light-damaged retina: A focus on retinal function and microglia activation. Experimental eye research. vol 188. 2020-02-21. PMID:31520599. |
the light damage model is characterised by oxidative stress upregulation followed by photoreceptor death and microglia activation in the outer retina. |
2020-02-21 |
2023-08-13 |
human |
| A Tisi, M Passacantando, M Ciancaglini, R Maccaron. Nanoceria neuroprotective effects in the light-damaged retina: A focus on retinal function and microglia activation. Experimental eye research. vol 188. 2020-02-21. PMID:31520599. |
the electrical responses of the retina and the microglia number and morphology are clearly modulated by the treatment, supporting the beneficial effects of cerium oxide nanoparticles to counteract the degeneration processes in the retina. |
2020-02-21 |
2023-08-13 |
human |
| Gurugirijha Rathnasamy, Wallace S Foulds, Eng-Ang Ling, Charanjit Kau. Retinal microglia - A key player in healthy and diseased retina. Progress in neurobiology. vol 173. 2020-02-17. PMID:29864456. |
retinal microglia - a key player in healthy and diseased retina. |
2020-02-17 |
2023-08-13 |
Not clear |
| Gurugirijha Rathnasamy, Wallace S Foulds, Eng-Ang Ling, Charanjit Kau. Retinal microglia - A key player in healthy and diseased retina. Progress in neurobiology. vol 173. 2020-02-17. PMID:29864456. |
microglia, the resident immune cells of the brain and retina, are constantly engaged in the surveillance of their surrounding neural tissue. |
2020-02-17 |
2023-08-13 |
Not clear |