| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zan Zhou, Wen-Jun Jiang, Yan-Ping Wang, Jun-Qiang Si, Xian-Si Zeng, Li L. CD36-mediated ROS/PI3K/AKT signaling pathway exacerbates cognitive impairment in APP/PS1 mice after noise exposure. The Science of the total environment. 2024-09-05. PMID:39233068. |
the changes in cd36 expression elevated oxidative stress levels in the hippocampus and entorhinal cortex, leading to a decrease in pi3k/akt phosphorylation, which in turn increased m1-type microglia and a1-type astrocytes while reducing the numbers of m2-type microglia and a2-type astrocytes. |
2024-09-05 |
2024-09-08 |
mouse |
| Seyedeh Parisa Navabi, Firuzeh Badreh, Maryam Khombi Shooshtari, Somayeh Hajipour, Sadegh Moradi Vastegani, Seyed Esmaeil Khoshna. Microglia-induced neuroinflammation in hippocampal neurogenesis following traumatic brain injury. Heliyon. vol 10. issue 16. 2024-09-02. PMID:39220913. |
the important process of neurogenesis in the hippocampus, which includes the production, maturation and integration of new neurons, is affected by tbi due to microglia activation and the inflammatory response. |
2024-09-02 |
2024-09-04 |
Not clear |
| Seyedeh Parisa Navabi, Firuzeh Badreh, Maryam Khombi Shooshtari, Somayeh Hajipour, Sadegh Moradi Vastegani, Seyed Esmaeil Khoshna. Microglia-induced neuroinflammation in hippocampal neurogenesis following traumatic brain injury. Heliyon. vol 10. issue 16. 2024-09-02. PMID:39220913. |
to date, the intracellular signaling pathways that trigger microglia activation following tbi, as well as the effects of microglia on hippocampal neurogenesis, are poorly understood. |
2024-09-02 |
2024-09-04 |
Not clear |
| Seyedeh Parisa Navabi, Firuzeh Badreh, Maryam Khombi Shooshtari, Somayeh Hajipour, Sadegh Moradi Vastegani, Seyed Esmaeil Khoshna. Microglia-induced neuroinflammation in hippocampal neurogenesis following traumatic brain injury. Heliyon. vol 10. issue 16. 2024-09-02. PMID:39220913. |
in this review article, we discuss the effects of microglia-induced neuroinflammation on hippocampal neurogenesis following tbi, as well as the intracellular signaling pathways of microglia activation. |
2024-09-02 |
2024-09-04 |
Not clear |
| Kai Zhou, Georgios Alkis Zisiadis, Monique Havermans, Adamantia Fragkopoulou, Cecilia Dominguez, Makiko Ohshima, Ahmed M Osman, Carlos F D Rodrigues, Klas Blomgre. Microglia depletion and repopulation do not alter the effects of cranial irradiation on hippocampal neurogenesis. Brain, behavior, and immunity. 2024-09-01. PMID:39218233. |
microglia depletion and repopulation do not alter the effects of cranial irradiation on hippocampal neurogenesis. |
2024-09-01 |
2024-09-04 |
Not clear |
| Yang Liu, Xiaokang Meng, Changfa Tang, Lan Zheng, Kun Tao, Wen Gu. Aerobic exercise modulates RIPK1-mediated MAP3K5/JNK and NF-κB pathways to suppress microglia activation and neuroinflammation in the hippocampus of D-gal-induced accelerated aging mice. Physiology & behavior. vol 286. 2024-08-25. PMID:39181380. |
aerobic exercise modulates ripk1-mediated map3k5/jnk and nf-κb pathways to suppress microglia activation and neuroinflammation in the hippocampus of d-gal-induced accelerated aging mice. |
2024-08-25 |
2024-08-28 |
mouse |
| Yang Liu, Xiaokang Meng, Changfa Tang, Lan Zheng, Kun Tao, Wen Gu. Aerobic exercise modulates RIPK1-mediated MAP3K5/JNK and NF-κB pathways to suppress microglia activation and neuroinflammation in the hippocampus of D-gal-induced accelerated aging mice. Physiology & behavior. vol 286. 2024-08-25. PMID:39181380. |
microglia activation-induced neuroinflammation is a risk factor for cognitive dysfunction in the hippocampus during the early stages of neurodegenerative diseases. |
2024-08-25 |
2024-08-28 |
mouse |
| Yang Liu, Xiaokang Meng, Changfa Tang, Lan Zheng, Kun Tao, Wen Gu. Aerobic exercise modulates RIPK1-mediated MAP3K5/JNK and NF-κB pathways to suppress microglia activation and neuroinflammation in the hippocampus of D-gal-induced accelerated aging mice. Physiology & behavior. vol 286. 2024-08-25. PMID:39181380. |
we found that aerobic exercise significantly promoted the survival of hippocampal neurons, inhibited microglia activation, and decreased the expression of inflammatory cytokines tnf-α, il-1α, il-1β, and chemokines cxcl-1, cxcr-2 in d-galactose model mice. |
2024-08-25 |
2024-08-28 |
mouse |
| Lixia Luo, Shitong Lin, Guoli Hu, Jiahui Wu, Yulin Hu, Fengjing Nong, Cheng Lu, Rongbin Chen, Jin Li. Molecular mechanism of Rolupram reducing neuroinflammation in noise induced tinnitus mice through TLR4/NF kB/NLRP3 protein/caspase-1/IL-1 β signaling pathway. International journal of biological macromolecules. 2024-08-24. PMID:39181359. |
immunohistochemistry and immunofluorescence were used to determine the activation of microglia in the hippocampus of noise induced tinnitus mice. |
2024-08-24 |
2024-08-28 |
mouse |
| Yu Shi, Xiangyu Guo, Jie Zhang, Hanchi Zhou, Bei Sun, Jing Fen. Corrigendum to "DNA binding protein HMGB1 secreted by activated microglia promotes the apoptosis of hippocampal neurons in diabetes complicated with OSA" [Brain Behav. Immun. 73 (2018) 482-492]. Brain, behavior, and immunity. 2024-08-24. PMID:39181822. |
corrigendum to "dna binding protein hmgb1 secreted by activated microglia promotes the apoptosis of hippocampal neurons in diabetes complicated with osa" [brain behav. |
2024-08-24 |
2024-08-28 |
Not clear |
| Xiaoxing Mo, Ruijie Cheng, Lihui Shen, Nian Liu, Yunhong Sun, Shan Lin, Guanhua Jiang, Xiaoqin Li, Xiaobo Peng, Yan Zhang, Yuxiao Liao, Hong Yan, Liegang Li. Yeast β-glucan alleviates high-fat diet-induced Alzheimer's disease-like pathologies in rats via the gut-brain axis. International journal of biological macromolecules. 2024-08-23. PMID:39179066. |
in the hippocampus, bg alleviated hfd-induced the activation of astrocytes, microglia, nod-like receptor thermal protein domain associated protein 3 (nlrp3) inflammasome pathway, and ad-like pathologies. |
2024-08-23 |
2024-08-27 |
rat |
| Gaia Piccioni, Nunzia Maisto, Asia d'Ettorre, Georgios Strimpakos, Robert Nisticò, Viviana Triaca, Dalila Mang. Switch to phagocytic microglia by CSFR1 inhibition drives amyloid-beta clearance from glutamatergic terminals rescuing LTP in acute hippocampal slices. Translational psychiatry. vol 14. issue 1. 2024-08-23. PMID:39179543. |
switch to phagocytic microglia by csfr1 inhibition drives amyloid-beta clearance from glutamatergic terminals rescuing ltp in acute hippocampal slices. |
2024-08-23 |
2024-08-27 |
Not clear |
| Lea Gabele, Isabell Bochow, Nele Rieke, Christian Sieben, Kristin Michaelsen-Preusse, Shirin Hosseini, Martin Kort. H7N7 viral infection elicits pronounced, sex-specific neuroinflammatory responses Frontiers in cellular neuroscience. vol 18. 2024-08-22. PMID:39171200. |
in conclusion, our findings underscore the utility of primary hippocampal cultures, incorporating microglia, as an effective model to study sex-specific, virus-induced effects on brain-resident cells. |
2024-08-22 |
2024-08-24 |
mouse |
| Paige L Graney, Evelyn L Sarno, Jessie E Miller, Christine K Wagne. Implications of Developmental 17-OHPC Exposure on the Mesocorticolimbic Serotonergic and Dopaminergic Pathways and Adolescent Mood-Related Behavior in Rats. Developmental psychobiology. vol 66. issue 6. 2024-08-21. PMID:39164823. |
irregular microglia activational phenotype and number were also observed in the hippocampus of 17-ohpc-exposed males. |
2024-08-21 |
2024-08-23 |
rat |
| Xiyue Wen, Jinyue H. Targeting STAT3 signaling pathway in the treatment of Alzheimer's disease with compounds from natural products. International immunopharmacology. vol 141. 2024-08-20. PMID:39163684. |
this occurs primarily through the jak2-stat3 signaling pathway, which impacts microglia, astrocytes, and hippocampal neurons. |
2024-08-20 |
2024-08-23 |
Not clear |
| Houyu Zhao, Kun Liang, Zeyuan Yu, Yukun Wen, Xuhua Yu, Jiayun Xin, Tingting Zhang, Xianpeng Zu, Yiqun Fan. CCR3 knockdown attenuates prolonged underwater operations-induced cognitive impairment via alleviating microglia-mediated neuroinflammation. iScience. vol 27. issue 8. 2024-08-19. PMID:39156650. |
knockdown of ccr3 significantly rescued cognitive impairment and hippocampal dysfunction and reversed the upregulation of pro-inflammatory cytokines, by switching the activated microglia from a pro-inflammatory to a neuroprotective phenotype. |
2024-08-19 |
2024-08-21 |
Not clear |
| Jiao Yang, Ji-Heng Cai, Tong-Xuan Wu, Zhi-Qiang Gao, Chao Zhou, Qi Wu, Miao-Jin J. Salvinorin A ameliorates pilocarpine-induced seizures by regulating hippocampal microglia polarization. Journal of ethnopharmacology. 2024-08-18. PMID:39154669. |
salvinorin a ameliorates pilocarpine-induced seizures by regulating hippocampal microglia polarization. |
2024-08-18 |
2024-08-21 |
Not clear |
| Yunli Fang, Hainan Pan, Haojie Zhu, Hanxiao Wang, Minxiu Ye, Jie Ren, Jie Peng, Jinxin Li, Xu Lu, Chao Huan. Intranasal LAG3 antibody infusion induces a rapid antidepressant effect via the hippocampal ERK1/2-BDNF signaling pathway in chronically stressed mice. Neuropharmacology. 2024-08-17. PMID:39153731. |
in a recent study, chronic systemic administration of a lag3 antibody that readily penetrates the brain was reported to reverse chronic stress-induced hippocampal microglia decline and depression-like behaviors. |
2024-08-17 |
2024-08-20 |
mouse |
| Meetu Wadhwa, Amit Prabhakar, Koushik Ray, Koustav Roy, Punita Kumari, Prabhash Kumar Jha, Krishna Kishore, Sanjeev Kumar, Usha Panjwan. Retraction Note: Inhibiting the microglia activation improves the spatial memory and adult neurogenesis in rat hippocampus during 48 h of sleep deprivation. Journal of neuroinflammation. vol 21. issue 1. 2024-08-17. PMID:39154017. |
retraction note: inhibiting the microglia activation improves the spatial memory and adult neurogenesis in rat hippocampus during 48 h of sleep deprivation. |
2024-08-17 |
2024-08-20 |
rat |
| Sergio Passarella, Shananthan Kethiswaran, Karina Brandes, I-Chin Tsai, Kristin Cebulski, Andrea Kröger, Daniela C Dieterich, Peter Landgra. Alteration of cGAS-STING signaling pathway components in the mouse cortex and hippocampus during healthy brain aging. Frontiers in aging neuroscience. vol 16. 2024-08-16. PMID:39149145. |
contrastingly, the hippocampus did not exhibit increased cgas activity with aging, but there was a notable elevation in sting levels, particularly in microglia, neurons and astrocytes. |
2024-08-16 |
2024-08-18 |
mouse |