| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Martine Lamy, Ernest V Pedapati, Kelli L Dominick, Logan K Wink, Craig A Erickso. Recent Advances in the Pharmacological Management of Behavioral Disturbances Associated with Autism Spectrum Disorder in Children and Adolescents. Paediatric drugs. vol 22. issue 5. 2020-11-02. PMID:32686015. |
research into the pathophysiology of asd has led to new targets for pharmacologic therapy including the neuroimmune system, the endocannabinoid system, and the glutamatergic neurotransmitter system. |
2020-11-02 |
2023-08-13 |
Not clear |
| Anupam Raina, Sameehan Mahajani, Mathias Bähr, Sebastian Kügle. Neuronal Trans-differentiation by Transcription Factors Ascl1 and Nurr1: Induction of a Dopaminergic Neurotransmitter Phenotype in Cortical GABAergic Neurons. Molecular neurobiology. vol 57. issue 1. 2020-10-07. PMID:31317490. |
only neurons of gabaergic phenotype could be trans-differentiated towards a dopaminergic neurotransmitter phenotype, while for glutamatergic neurons, this process proved to be neurotoxic. |
2020-10-07 |
2023-08-13 |
rat |
| Ahmed Al-Qassabi, Seyed-Mohammad Fereshtehnejad, Ronald B Postum. Sleep Disturbances in the Prodromal Stage of Parkinson Disease. Current treatment options in neurology. vol 19. issue 6. 2020-10-01. PMID:28466429. |
disturbances in serotonergic, cholinergic, dopaminergic, and glutamatergic neurotransmitter systems have made sleep disorders potential candidates for prodromal pd. |
2020-10-01 |
2023-08-13 |
Not clear |
| Igne Sinkeviciute, Marieke Begemann, Merel Prikken, Bob Oranje, Erik Johnsen, Wan U Lei, Kenneth Hugdahl, Rune A Kroken, Carina Rau, Jolien D Jacobs, Silvia Mattaroccia, Iris E Somme. Efficacy of different types of cognitive enhancers for patients with schizophrenia: a meta-analysis. NPJ schizophrenia. vol 4. issue 1. 2020-10-01. PMID:30361502. |
when analyzing each neurotransmitter system separately, agents acting predominantly on the glutamatergic system showed a small significant effect on overall cognition (k = 29, hedges' g = 0.19, p = 0.01), as well as on working memory (k = 20, hedges' g = 0.13, p = 0.04). |
2020-10-01 |
2023-08-13 |
Not clear |
| Marcos Ucha, David Roura-Martínez, Ana Contreras, Sheyla Pinto-Rivero, Javier Orihuel, Emilio Ambrosio, Alejandro Higuera-Mata. Impulsive Action and Impulsive Choice Are Differentially Associated With Gene Expression Variations of the GABA Frontiers in behavioral neuroscience. vol 13. 2020-10-01. PMID:30842730. |
the neurochemical basis of impulsivity is still being elucidated, however, in recent years a role for the endocannabinoids and the related glutamatergic and gabaergic neurotransmitter systems has been suggested. |
2020-10-01 |
2023-08-13 |
rat |
| Jing Zhou, Zhiyin Liao, Jia Jia, Jin-Liang Chen, Qian Xia. The effects of resveratrol feeding and exercise training on the skeletal muscle function and transcriptome of aged rats. PeerJ. vol 7. 2020-10-01. PMID:31304063. |
the most enriched go terms in the resveratrol group vs. the old group were primarily associated with neurotransmitter transport and synaptic vesicle, and the upregulated kegg pathways included synaptic vesicle cycle, nicotine addiction, retinol metabolism, insulin secretion, retrograde endocannabinoid signaling, and glutamatergic synapse. |
2020-10-01 |
2023-08-13 |
rat |
| Kazushige Mizoguchi, Yasushi Ikarash. Cellular Pharmacological Effects of the Traditional Japanese Kampo Medicine Yokukansan on Brain Cells. Frontiers in pharmacology. vol 8. 2020-09-30. PMID:28979206. |
regarding the pharmacological mechanisms underlying its efficacy, we recently reviewed the multiple effects of yks on the neurotransmitter systems (e.g., glutamatergic, serotonergic, dopaminergic, cholinergic, gabaergic, and adrenergic neurotransmission) in various brain regions that are related to the psychological, emotional, cognitive, or memory functions. |
2020-09-30 |
2023-08-13 |
Not clear |
| Cristy Phillips, Atoossa Fahim. Immune and Neuroprotective Effects of Physical Activity on the Brain in Depression. Frontiers in neuroscience. vol 12. 2020-09-30. PMID:30093853. |
physical activity optimizes the stress response, neurotransmitter level and function (e.g., serotonergic, noradrenergic, dopaminergic, and glutamatergic), myokine production (e.g., interleukin-6), transcription factor levels and correlates [e.g., peroxisome proliferator-activated receptor c coactivator-1α [pgc-1α], mitochondrial density, nitric oxide pathway activity, ca |
2020-09-30 |
2023-08-13 |
Not clear |
| Macarena Gómez de Salazar, Cristina Grau, Francisco Ciruela, Xavier Altafa. Phosphoproteomic Alterations of Ionotropic Glutamate Receptors in the Hippocampus of the Ts65Dn Mouse Model of Down Syndrome. Frontiers in molecular neuroscience. vol 11. 2020-09-30. PMID:30140203. |
hence, we hypothesized that dysregulation of phosphorylation/dephosphorylation balance might affect neuronal function, which in turn could contribute to the glutamatergic neurotransmitter alterations observed in ds. |
2020-09-30 |
2023-08-13 |
mouse |
| Andrea Pedroni, Konstantinos Ampatzi. Large-Scale Analysis of the Diversity and Complexity of the Adult Spinal Cord Neurotransmitter Typology. iScience. vol 19. 2020-09-30. PMID:31542702. |
as a first direct application, we investigated the neurotransmitter diversity in the putative glutamatergic spinal v2a-interneuron assembly. |
2020-09-30 |
2023-08-13 |
zebrafish |
| Istvan Mod. The GAD-given Right of Dentate Gyrus Granule Cells to Become GABAergic. Epilepsy currents. vol 2. issue 5. 2020-09-29. PMID:15309121. |
the vesicular zinc found in many glutamatergic terminals also may be considered to be a second neurotransmitter, based on its vesicular packaging with the aid of a specific vesicular transporter, and its postsynaptic actions through high-affinity binding sites and permeation through certain channels (2). |
2020-09-29 |
2023-08-12 |
Not clear |
| Hang Su, Tianzhen Chen, Na Zhong, Haifeng Jiang, Jiang Du, Ke Xiao, Ding Xu, Zheng Wang, Min Zha. γ-aminobutyric acid and glutamate/glutamine alterations of the left prefrontal cortex in individuals with methamphetamine use disorder: a combined transcranial magnetic stimulation-magnetic resonance spectroscopy study. Annals of translational medicine. vol 8. issue 6. 2020-09-28. PMID:32355791. |
gabaergic and glutamatergic neurotransmitter systems are critical in the pathophysiology of addiction and represent potential targets for repetitive transcranial magnetic stimulation (rtms). |
2020-09-28 |
2023-08-13 |
Not clear |
| O Yu Fedorenko, S A Ivanov. [A new look at the genetics of neurocognitive deficits in schizophrenia]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 120. issue 8. 2020-09-16. PMID:32929943. |
the article presents current literature data on genetic studies of neurocognitive deficit in schizophrenia, including the genes of neurotransmitter systems (dopaminergic, glutamatergic, and serotonergic); genes analyzed in genome-wide association studies (gwas), as well as other genetic factors related to the pathophysiological mechanisms underlying schizophrenia and neurocognitive disorders. |
2020-09-16 |
2023-08-13 |
Not clear |
| Gabriela Pandini Silote, Ariandra Sartim, Amanda Sales, Amanda Eskelund, F S Guimarães, Gregers Wegener, Samia Joc. Emerging evidence for the antidepressant effect of cannabidiol and the underlying molecular mechanisms. Journal of chemical neuroanatomy. vol 98. 2020-08-17. PMID:31039391. |
cbd has a complex pharmacology, with the ability to interact with multiple neurotransmitter systems involved in depression, including the serotonergic, glutamatergic, and endocannabinoid systems. |
2020-08-17 |
2023-08-13 |
Not clear |
| John Williamson, Tanveer Singh, Jaideep Kapu. Neurobiology of organophosphate-induced seizures. Epilepsy & behavior : E&B. vol 101. issue Pt B. 2020-08-03. PMID:31399343. |
organophosphate agents enhance glutamatergic transmission by enhancing neurotransmitter release. |
2020-08-03 |
2023-08-13 |
Not clear |
| Urjita H Shah, Javier González-Maes. Serotonin and Glutamate Interactions in Preclinical Schizophrenia Models. ACS chemical neuroscience. vol 10. issue 7. 2020-06-11. PMID:30807107. |
the serotonergic and glutamatergic neurotransmitter systems have both been implicated in the pathophysiology of schizophrenia, and there are multiple lines of evidence to demonstrate that they can interact in a functionally relevant manner. |
2020-06-11 |
2023-08-13 |
Not clear |
| Maria Nicol Colombo, Maura Francolin. Glutamate at the Vertebrate Neuromuscular Junction: From Modulation to Neurotransmission. Cells. vol 8. issue 9. 2020-05-26. PMID:31466388. |
finally, in adult rodents, by diverting descending spinal glutamatergic axons to a denervated muscle, a functional reinnervation can be achieved with the formation of new neuromuscular junctions that use glutamate as neurotransmitter and express ionotropic glutamate receptors and other markers of central glutamatergic synapses. |
2020-05-26 |
2023-08-13 |
Not clear |
| Xi Chen, Siddartha M Tamang, Fei Du, Dost Ongu. Glutamate diffusion in the rat brain in vivo under light and deep anesthesia conditions. Magnetic resonance in medicine. vol 82. issue 1. 2020-05-25. PMID:30860289. |
glutamate (glu) is the most abundant neurotransmitter in the human central nervous system and glutamatergic neurotransmission has been implicated in many common and severe neuropsychiatric disorders. |
2020-05-25 |
2023-08-13 |
human |
| Serena Boccella, Ida Marabese, Francesca Guida, Livio Luongo, Sabatino Maione, Enza Palazz. The Modulation of Pain by Metabotropic Glutamate Receptors 7 and 8 in the Dorsal Striatum. Current neuropharmacology. vol 18. issue 1. 2020-05-20. PMID:31210112. |
a way to counteract glutamatergic hyperactivation is through the activation of group iii metabotropic glutamate receptors (mglurs), which are located on presynaptic terminals inhibiting neurotransmitter release. |
2020-05-20 |
2023-08-13 |
Not clear |
| Lewis M Sherer, Elizabeth Catudio Garrett, Hannah R Morgan, Edmond D Brewer, Lucy A Sirrs, Harold K Shearin, Jessica L Williams, Brian D McCabe, R Steven Stowers, Sarah J Certe. Octopamine neuron dependent aggression requires dVGLUT from dual-transmitting neurons. PLoS genetics. vol 16. issue 2. 2020-05-11. PMID:32097408. |
here, we establish that the majority of drosophila octopamine (oa) neurons are also glutamatergic and identify the individual contributions of each neurotransmitter on sex-specific behaviors. |
2020-05-11 |
2023-08-13 |
drosophila_melanogaster |