| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shubo Jin, Xavier J Maddern, Erin J Campbell, Andrew J Lawrenc. Examining Ventral Subiculum and Basolateral Amygdala Projections to the Nucleus Accumbens Shell: Differential Expression Of Vglut1, Vglut2 and Vgat in the Rat. Neuroscience letters. 2022-08-29. PMID:36038028. |
to determine the neurotransmitter identity of projection neurons, we combined retrograde tracing with rnascope in-situ hybridization, using mrna probes against vesicular transporters associated with glutamatergic (vglut1 - slc17a7, vglut2 - slc17a6) or gabaergic (vgat - slc32a1) neurotransmission. |
2022-08-29 |
2023-08-14 |
rat |
| Ziqian Cheng, Jingyun Su, Kai Zhang, Huiyi Jiang, Bingjin L. Epigenetic Mechanism of Early Life Stress-Induced Depression: Focus on the Neurotransmitter Systems. Frontiers in cell and developmental biology. vol 10. 2022-07-22. PMID:35865627. |
many reports indicate that different types of els induce epigenetic modifications of genes involved in the neurotransmitter systems, such as the dopaminergic system, the serotonergic system, the gamma-aminobutyric acid (gaba)-ergic system, and the glutamatergic system, which further regulate gene expression and ultimately induce depression-like behaviors. |
2022-07-22 |
2023-08-14 |
Not clear |
| Carolina Montenegro-Venegas, Debarpan Guhathakurta, Eneko Pina-Fernandez, Maria Andres-Alonso, Florian Plattner, Eckart D Gundelfinger, Anna Fejtov. Bassoon controls synaptic vesicle release via regulation of presynaptic phosphorylation and cAMP. EMBO reports. 2022-06-29. PMID:35766170. |
these data reveal that bassoon organises sv pools in glutamatergic synapses via regulation of presynaptic phosphorylation and camp homeostasis and indicate a role of cdk5/pde4/camp axis in the control of neurotransmitter release. |
2022-06-29 |
2023-08-14 |
Not clear |
| Birgitta Dresp-Langley, Axel Hut. Digital Addiction and Sleep. International journal of environmental research and public health. vol 19. issue 11. 2022-06-10. PMID:35682491. |
the syndrome has been linked to the known chronic effects of all drugs, producing disturbances in cellular and molecular mechanisms of the gabaergic and glutamatergic neurotransmitter systems. |
2022-06-10 |
2023-08-14 |
Not clear |
| Vanessa Jorge Henriques, Angela Chiavegato, Giorgio Carmignoto, Marta Gómez-Gonzal. Astrocytes Modulate Somatostatin Interneuron Signaling in the Visual Cortex. Cells. vol 11. issue 9. 2022-05-14. PMID:35563706. |
at glutamatergic synapses, astrocytes respond to the neurotransmitter glutamate with intracellular ca |
2022-05-14 |
2023-08-13 |
Not clear |
| Jessica L Armstrong, Clinton E Cana. Targeting 5-HT FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35554052. |
mmp-9 degrades perineuronal nets (pnns) that stabilize glutamatergic and gabaergic neurotransmission, and imbalance in these neurotransmitter systems is a hallmark of fxs, suggesting correcting mmp-9 overactivity may restore neuronal homeostasis in fxs by normalizing pnns. |
2022-05-13 |
2023-08-13 |
mouse |
| Arianna De Rosa, Andrea Fontana, Tommaso Nuzzo, Martina Garofalo, Anna Di Maio, Daniela Punzo, Massimiliano Copetti, Alessandro Bertolino, Francesco Errico, Antonio Rampino, Andrea de Bartolomeis, Alessandro Usiell. Machine Learning algorithm unveils glutamatergic alterations in the post-mortem schizophrenia brain. NPJ schizophrenia. vol 8. issue 1. 2022-02-26. PMID:35217646. |
moreover, by quantitative rt-pcr and western blotting we analyzed, respectively, the mrna and protein levels of pre- and post-synaptic key molecules involved in the glutamatergic synapse functioning, including glutamate receptors (nmda, ampa, metabotropic), their interacting scaffolding proteins (psd-95, homer1b/c), plasma membrane and vesicular glutamate transporters (eaat1, eaat2, vglut1, vglut2), enzymes involved either in glutamate-dependent gaba neurotransmitter synthesis (gad65 and 67), or in post-synaptic nmda receptor-mediated signaling (camkiiα) and the pre-synaptic marker synapsin-1. |
2022-02-26 |
2023-08-13 |
Not clear |
| B Spurny-Dworak, P Handschuh, M Spies, U Kaufmann, R Seiger, M Klöbl, M E Konadu, M B Reed, V Ritter, P Baldinger-Melich, W Bogner, G S Kranz, R Lanzenberge. Effects of sex hormones on brain GABA and glutamate levels in a cis- and transgender cohort. Psychoneuroendocrinology. vol 138. 2022-02-17. PMID:35176535. |
sex hormones affect the gabaergic and glutamatergic neurotransmitter system as demonstrated in animal studies. |
2022-02-17 |
2023-08-13 |
human |
| Davide Cenci, Manuel Glauco Carbone, Camilla Callegari, Icro Maremman. Psychomotor Symptoms in Chronic Cocaine Users: An Interpretative Model. International journal of environmental research and public health. vol 19. issue 3. 2022-02-15. PMID:35162918. |
specifically, we supposed that the chronic administration of cocaine produces important neurobiological changes, causing a complex dysregulation of various neurotransmitter systems, mainly affecting subcortical structures and the dopaminergic and glutamatergic pathways. |
2022-02-15 |
2023-08-13 |
Not clear |
| Joyce Keife. Regulation of AMPAR trafficking in synaptic plasticity by BDNF and the impact of neurodegenerative disease. Journal of neuroscience research. 2022-02-07. PMID:35128708. |
research demonstrates that the neural mechanisms underlying synaptic plasticity and learning and memory involve mobilization of ampa-type neurotransmitter receptors at glutamatergic synaptic contacts, and that these mechanisms are targeted during neurodegenerative disease. |
2022-02-07 |
2023-08-13 |
Not clear |
| Sarah J Certel, Evelyne Ruchti, Brian D McCabe, R Steven Stower. A conditional glutamatergic synaptic vesicle marker for Drosophila. G3 (Bethesda, Md.). 2022-01-31. PMID:35100385. |
the utility of smflag-vglut is demonstrated by glutamatergic neurotransmitter phenotyping of 26 different central complex neuron types of which nine were established to be glutamatergic. |
2022-01-31 |
2023-08-13 |
drosophila_melanogaster |
| Sarah J Certel, Evelyne Ruchti, Brian D McCabe, R Steven Stower. A conditional glutamatergic synaptic vesicle marker for Drosophila. G3 (Bethesda, Md.). 2022-01-31. PMID:35100385. |
the use of smflag for glutamatergic neurotransmitter phenotyping and identification of glutamate release sites can be extended to any drosophila neuron(s) represented by a binary transcription system driver. |
2022-01-31 |
2023-08-13 |
drosophila_melanogaster |
| Nadine Huber, Dorit Hoffmann, Raisa Giniatullina, Hannah Rostalski, Stina Leskelä, Mari Takalo, Teemu Natunen, Eino Solje, Anne M Remes, Rashid Giniatullin, Mikko Hiltunen, Annakaisa Haapasal. C9orf72 hexanucleotide repeat expansion leads to altered neuronal and dendritic spine morphology and synaptic dysfunction. Neurobiology of disease. 2021-12-16. PMID:34915153. |
ftld is accompanied by changes in several neurotransmitter systems, including the glutamatergic, gabaergic, dopaminergic, and serotonergic systems and many clinical symptoms can be explained by disturbances in these systems. |
2021-12-16 |
2023-08-13 |
mouse |
| Tássia Limana da Silveira, Marina Lopes Machado, Fabiane Bicca Obetine Baptista, Débora Farina Gonçalves, Diane Duarte Hartmann, Larissa Marafiga Cordeiro, Aline Franzen da Silva, Cristiane Lenz Dalla Corte, Michael Aschner, Felix Alexandre Antunes Soare. Caenorhabditis elegans as a model for studies on quinolinic acid-induced NMDAR-dependent glutamatergic disorders. Brain research bulletin. vol 175. 2021-12-10. PMID:34271120. |
quinolinic acid (quin) is an agonist of the neurotransmitter glutamate (glu) capable of binding to n-methyl-d-aspartate receptors (nmdar) increasing glutamatergic signaling. |
2021-12-10 |
2023-08-13 |
caenorhabditis_elegans |
| Victor N Almeida, Marcia Radanovi. Semantic priming and neurobiology in schizophrenia: A theoretical review. Neuropsychologia. vol 163. 2021-12-06. PMID:34655651. |
we review and theoretically evaluate the neurotransmitter systems (dopaminergic, gabaergic and glutamatergic) and neurobiological underpinnings of behavioural and electrophysiological (n400) semantic priming in the pathology, and the main hypotheses on their geneses: a disinhibition of the semantic spread of activation, a disorganised semantic storage or noisy lexical-semantic associations, a psychomotor artefact, an artefact of relatedness proportions, or an inability to mobilise contextual information. |
2021-12-06 |
2023-08-13 |
Not clear |
| Ana Sofía Vallés, Francisco J Barrante. Nanoscale Sub-Compartmentalization of the Dendritic Spine Compartment. Biomolecules. vol 11. issue 11. 2021-11-30. PMID:34827695. |
this review discusses the functional relevance of compartmentalization and nanodomain organization in synaptic transmission and plasticity and exemplifies the importance of this parcelization in various neurotransmitter signaling systems operating at dendritic spines, using two fast ligand-gated ionotropic receptors, the nicotinic acetylcholine receptor and the glutamatergic receptor, and a second-messenger g-protein coupled receptor, the cannabinoid receptor, as paradigmatic examples. |
2021-11-30 |
2023-08-13 |
Not clear |
| Ruiqing N. Positron Emission Tomography in Animal Models of Alzheimer's Disease Amyloidosis: Translational Implications. Pharmaceuticals (Basel, Switzerland). vol 14. issue 11. 2021-11-30. PMID:34832961. |
in this review, we focus on recent positron emission tomography studies of cerebral amyloid-beta accumulation, hypoglucose metabolism, synaptic and neurotransmitter receptor deficits (cholinergic and glutamatergic system), blood-brain barrier impairment, and neuroinflammation (microgliosis and astrocytosis) in animal models of alzheimer's disease amyloidosis. |
2021-11-30 |
2023-08-13 |
Not clear |
| James T McKenna, Chun Yang, Thomas Bellio, Marissa B Anderson-Chernishof, Mackenzie C Gamble, Abigail Hulverson, John G McCoy, Stuart Winston, Erik Hodges, Fumi Katsuki, James M McNally, Radhika Basheer, Ritchie E Brow. Characterization of basal forebrain glutamate neurons suggests a role in control of arousal and avoidance behavior. Brain structure & function. vol 226. issue 6. 2021-11-29. PMID:33997911. |
glutamatergic neurons are the least well-understood of the three main bf neurotransmitter phenotypes. |
2021-11-29 |
2023-08-13 |
mouse |
| Luca Zangrandi, Christoph Schwarze. The Kappa Opioid Receptor System in Temporal Lobe Epilepsy. Handbook of experimental pharmacology. vol 271. 2021-11-26. PMID:33712941. |
indeed, kor agonists induce inhibition of presynaptic neurotransmitter release, as well as postsynaptic hyperpolarization in glutamatergic neurons, both producing anticonvulsant effects.the development of new approaches to modulate the complex kor signalling cascade (e.g. |
2021-11-26 |
2023-08-13 |
mouse |
| Sanders A McDougall, Jasmine A M Robinson, Devon C Gleason, Laura L Cotte. Reciprocal cross-sensitization between cocaine and RU 24969 in male and female preweanling rats. Pharmacology, biochemistry, and behavior. vol 209. 2021-11-25. PMID:34437872. |
neuronal adaptations involving dopaminergic, glutamatergic, and serotonergic neurotransmitter systems are responsible for behavioral sensitization. |
2021-11-25 |
2023-08-13 |
rat |