| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Damian Mielecki, Elżbieta Salińsk. Group III metabotropic glutamate receptors: guardians against excitotoxicity in ischemic brain injury, with implications for neonatal contexts. Pharmacological reports : PR. 2024-09-19. PMID:39298028. |
their downstream signaling cascade results in the regulation of intracellular calcium levels, neuronal hyperpolarization, and reduced neurotransmitter release, effectively decreasing excitotoxic signaling without completely suppressing essential glutamatergic functions. |
2024-09-19 |
2024-09-22 |
Not clear |
| Leon D Lotter, Amin Saberi, Justine Y Hansen, Bratislav Misic, Casey Paquola, Gareth J Barker, Arun L W Bokde, Sylvane Desrivières, Herta Flor, Antoine Grigis, Hugh Garavan, Penny Gowland, Andreas Heinz, Rüdiger Brühl, Jean-Luc Martinot, Marie-Laure Paillère, Eric Artiges, Dimitri Papadopoulos Orfanos, Tomáš Paus, Luise Poustka, Sarah Hohmann, Juliane H Fröhner, Michael N Smolka, Nilakshi Vaidya, Henrik Walter, Robert Whelan, Gunter Schumann, Frauke Nees, Tobias Banaschewski, Simon B Eickhoff, Juergen Dukar. Regional patterns of human cortex development correlate with underlying neurobiology. Nature communications. vol 15. issue 1. 2024-09-16. PMID:39284858. |
in contrast, modeled cortical thickness change patterns during adulthood are best explained by cholinergic and glutamatergic neurotransmitter receptor and transporter distributions. |
2024-09-16 |
2024-09-19 |
human |
| Ehsan Raeis-Abdollahi, Payman Raise-Abdullahi, Ali Rashidy-Pour, Morvarid Meamar, Hassan Askar. Coffee's protective mechanisms against neurodegeneration. Progress in brain research. vol 288. 2024-08-21. PMID:39168556. |
coffee modulates neurotransmitter systems, including dopaminergic, cholinergic, and glutamatergic pathways implicated in neurodegeneration. |
2024-08-21 |
2024-08-24 |
Not clear |
| Darragh P Devin. The neuropathology of Self-Injurious Behavior: Studies using animal models. Brain research. 2024-08-20. PMID:39163896. |
animal models have implicated dysregulation of monoaminergic, glutamatergic, and other neurotransmitter systems in expression of self-injury, and these models have suggested neural targets for pharmacotherapy that have potential relevance for diverse clinical populations. |
2024-08-20 |
2024-08-23 |
Not clear |
| Vasiliki Epameinondas Georgakopoulou, Pagona Sklapani, Nikolaos Trakas, Russel J Reiter, Demetrios A Spandido. Exploring the association between melatonin and nicotine dependence (Review). International journal of molecular medicine. vol 54. issue 4. 2024-08-02. PMID:39092582. |
melatonin may influence neurotransmitter systems involved in addiction, such as the dopaminergic, glutamatergic, serotonergic and endogenous opioid systems. |
2024-08-02 |
2024-08-05 |
Not clear |
| Megan E Barra, Ken Solt, Xin Yu, Brian L Edlo. Restoring consciousness with pharmacologic therapy: Mechanisms, targets, and future directions. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2024-07-17. PMID:39019729. |
however, the relative contributions of monoaminergic, glutamatergic, cholinergic, gabaergic, and orexinergic neurotransmitter systems to recovery of consciousness after severe brain injury are unknown, and personalized approaches to targeted therapy have yet to be developed. |
2024-07-17 |
2024-07-20 |
Not clear |
| Hiroyuki Ichijo, Nguyen Thi Van Trang, Tomoya Nakamur. Topographic Organization of Glutamatergic and GABAergic Parvalbumin Positive Neurons in the Lateral Habenula. eNeuro. 2024-07-03. PMID:38960707. |
to achieve this, we investigated the proportions of the transmitter machinery in lhb pv neurons, including gabaergic, glutamatergic, serotonergic, cholinergic, and dopaminergic neurotransmitter markers, using transcriptome analysis, mrna in situ hybridization chain reaction, and immunohistochemistry. |
2024-07-03 |
2024-07-10 |
mouse |
| Audrey T Medeiros, Scott J Gratz, Ambar Delgado, Jason T Ritt, Kate M O'Connor-Gile. Ca2+ channel and active zone protein abundance intersects with input-specific synapse organization to shape functional synaptic diversity. bioRxiv : the preprint server for biology. 2024-05-30. PMID:37034654. |
we investigated the contributions of voltage-gated calcium channel (vgcc) abundance, spatial organization, and subunit composition to synapse diversity among and between synapses formed by two closely related drosophila glutamatergic motor neurons with distinct neurotransmitter release probabilities (pr). |
2024-05-30 |
2024-05-31 |
drosophila_melanogaster |
| Leon D Lotter, Amin Saberi, Justine Y Hansen, Bratislav Misic, Casey Paquola, Gareth J Barker, Arun L W Bokde, Sylvane Desrivieres, Herta Flor, Antoine Grigis, Hugh Garavan, Penny Gowland, Andreas Heinz, Ruediger Bruehl, Jean-Luc Martinot, Marie-Laure Paillere, Eric Artiges, Dimitri Papadopoulos Orfanos, Tomas Paus, Luise Poustka, Sarah Hohmann, Juliane H Froehner, Michael N Smolka, Nilakshi Vaidya, Henrik Walter, Robert Whelan, Gunter Schumann, Frauke Nees, Tobias Banaschewski, Simon B Eickhoff, Juergen Dukar. Regional patterns of human cortex development colocalize with underlying neurobiology. bioRxiv : the preprint server for biology. 2024-05-10. PMID:37205539. |
in contrast, modeled cortical change patterns during adulthood are best explained by cholinergic and glutamatergic neurotransmitter receptor and transporter distributions. |
2024-05-10 |
2024-05-27 |
human |
| Peyton Christine Bendis, Sydney Zimmerman, Anna Onisiforou, Panos Zanos, Polymnia Georgio. The impact of estradiol on serotonin, glutamate, and dopamine systems. Frontiers in neuroscience. vol 18. 2024-04-08. PMID:38586193. |
these neurotransmitter systems encompass the serotonergic, dopaminergic, and glutamatergic signaling pathways. |
2024-04-08 |
2024-04-10 |
human |
| Elizabeth McManus, Nils Muhlert, Niall W Dunca. InSpectro-Gadget: A Tool for Estimating Neurotransmitter and Neuromodulator Receptor Distributions for MRS Voxels. Neuroinformatics. 2024-02-22. PMID:38386228. |
in particular, some knowledge of likely local neurotransmitter receptor patterns can potentially give insights into the mechanistic environment gaba- and glutamatergic neurons are functioning in. |
2024-02-22 |
2024-02-24 |
human |
| Shivanshu Bajaj, Radhakrishnan Mahes. Converged avenues: depression and Alzheimer's disease- shared pathophysiology and novel therapeutics. Molecular biology reports. vol 51. issue 1. 2024-01-28. PMID:38281208. |
this includes neurotransmitter modulators, glutamatergic system modulators, mitochondrial modulators, antioxidant agents, hpa axis targeted therapy, inflammatory system targeted therapy, neurogenesis targeted therapy, repurposed anti-diabetic agents, and others. |
2024-01-28 |
2024-01-31 |
Not clear |
| Shubhrat Maheshwari, Aditya Sing. Navigating the Dementia Landscape: Biomarkers and Emerging Therapies. Ageing research reviews. 2024-01-12. PMID:38215913. |
tms has uncovered unique neurophysiological signatures, highlighting impaired plasticity, hyperexcitability, and altered connectivity in ad, while ftd displays differences in neurotransmitter systems, particularly gabaergic and glutamatergic circuits. |
2024-01-12 |
2024-01-15 |
Not clear |
| Sofía Illescas, Yaiza Diaz-Osorio, Anna Serradell, Lucía Toro-Soria, Uliana Musokhranvoa, Natalia Juliá-Palacios, Juliana Ribeiro-Constante, Xavier Altafaj, Mireia Olivella, Mar O'Callaghan, Alejandra Darling, Judith Armstrong, Rafael Artuch, Àngels García-Cazorla, Alfonso Oyarzába. Metabolic characterization of neurogenetic disorders involving glutamatergic neurotransmission. Journal of inherited metabolic disease. 2023-11-07. PMID:37932875. |
the study of the glutamatergic synapse using the same approach than classic neurotransmitter disorders is challenging due to the lack of biomarkers in the csf. |
2023-11-07 |
2023-11-08 |
mouse |
| Na Zhu, Charles A LeDuc, Ilene Fennoy, Blandine Laferrère, Claudia A Doege, Yufeng Shen, Wendy K Chung, Rudolph L Leibe. Rare predicted loss of function alleles in Bassoon (BSN) are associated with obesity. NPJ genomic medicine. vol 8. issue 1. 2023-10-21. PMID:37865656. |
bassoon (bsn) is a component of a hetero-dimeric presynaptic cytomatrix protein that orchestrates neurotransmitter release with piccolo (pclo) from glutamatergic neurons throughout the brain. |
2023-10-21 |
2023-11-08 |
Not clear |
| Daphne E Boucherie, Liesbeth Reneman, Henricus G Ruhé, Anouk Schrante. Neurometabolite changes in response to antidepressant medication: A systematic review of NeuroImage. Clinical. vol 40. 2023-10-09. PMID:37812859. |
these different types of medication may involve common neural pathways related to glutamatergic and gabaergic neurotransmitter systems, both of which have been implicated in mdd pathology. |
2023-10-09 |
2023-10-15 |
Not clear |
| Filippo Basagni, Jose A Ortega, Sine M Bertozzi, Andrea Armirotti, Maria Summa, Rosalia Bertorelli, Manuela Bartolini, Ian R Mellor, Martina Bedeschi, Giovanni Bottegoni, Vittorio Lembo, Anna Minarini, Andrea Cavalli, Michela Rosin. Galantamine-memantine hybrids for Alzheimer's disease: The influence of linker rigidity in biological activity and pharmacokinetic properties. European journal of medicinal chemistry. vol 261. 2023-09-21. PMID:37734258. |
neurodegenerative processes characterizing alzheimer's disease (ad) are strictly related to the impairment of cholinergic and glutamatergic neurotransmitter systems which provoke synaptic loss. |
2023-09-21 |
2023-10-07 |
Not clear |
| Joseph V Martin, Pradip K Sarka. Nongenomic roles of thyroid hormones and their derivatives in adult brain: are these compounds putative neurotransmitters? Frontiers in endocrinology. vol 14. 2023-09-13. PMID:37701902. |
furthermore, thyronines bind specifically to other defined neurotransmitter receptors, including gabaergic, catecholaminergic, glutamatergic, serotonergic and cholinergic systems. |
2023-09-13 |
2023-10-07 |
Not clear |
| Arantzazu Belloso-Iguerategui, Marta Zamarbide, Leyre Merino-Galan, Tatiana Rodríguez-Chinchilla, Belén Gago, Enrique Santamaria, Joaquín Fernández-Irigoyen, Carl W Cotman, G Aleph Prieto, Ana Quiroga-Varela, María Cruz Rodríguez-Oro. Hippocampal synaptic failure is an early event in experimental parkinsonism with subtle cognitive deficit. Brain : a journal of neurology. 2023-07-04. PMID:37403195. |
our results not only point to dopaminergic but also to glutamatergic and gabaergic dysfunction, highlighting the relevance of the three neurotransmitter systems in the ventral tegmental area-hippocampus interaction from the earliest stages of parkinsonism. |
2023-07-04 |
2023-08-14 |
human |
| Hong Lu, Long Zuo, Kyle M Roddick, Peng Zhang, Shinichiro Oku, Jessica Garden, Yuan Ge, Michael Bellefontaine, Mathias Delhaye, Richard E Brown, Ann Marie Crai. Alternative splicing and heparan sulfation converge on neurexin-1 to control glutamatergic transmission and autism-related behaviors. Cell reports. vol 42. issue 7. 2023-06-29. PMID:37384525. |
this is associated with reduced neurexin-1 protein level and reduced glutamatergic neurotransmitter release. |
2023-06-29 |
2023-08-14 |
mouse |