| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K M Kantak, L R Hegstrand, B Eichelma. Regional changes in monoamines and metabolites following defensive aggression in the rat. Brain research bulletin. vol 12. issue 3. 1984-07-19. PMID:6202379. |
pharmacological studies have demonstrated that shock-induced defensive fighting is modulated by manipulations of the serotonergic, noradrenergic and dopaminergic neurotransmitter systems. |
1984-07-19 |
2023-08-12 |
rat |
| D Parkinson, R R Rand. Ontogenesis of dopaminergic neurons in the post-natal rabbit retina: pre- and post-synaptic elements. Brain research. vol 315. issue 2. 1984-07-18. PMID:6144369. |
this suggests that the continued presence of neurotransmitter is not necessary for the developmental process to continue that the commitment of particular neurons to become dopaminergic may be made earlier than 5-6 days post-natally. |
1984-07-18 |
2023-08-12 |
rabbit |
| P K Seth, S V Chandr. Neurotransmitters and neurotransmitter receptors in developing and adult rats during manganese poisoning. Neurotoxicology. vol 5. issue 1. 1984-06-20. PMID:6144084. |
the short-term exposure produces an increase in the binding of dopaminergic antagonist [3h]-spiroperidol to striatal membranes without affecting the other neurotransmitter receptors at low doses (10 mg/kg x 15). |
1984-06-20 |
2023-08-12 |
mouse |
| C G Clough, K J Bergmann, M D Yah. Cholinergic and dopaminergic mechanisms in Parkinson's disease after long-term L-DOPA administration. Advances in neurology. vol 40. 1984-03-07. PMID:6695589. |
these findings are interpreted as indicating that the dopaminergic receptors are available for stimulation during the off phase but are not receiving sufficient neurotransmitter, that is, dopamine, to stimulate their activity. |
1984-03-07 |
2023-08-12 |
Not clear |
| G D Ellison, M S Eiso. Continuous amphetamine intoxication: an animal model of the acute psychotic episode. Psychological medicine. vol 13. issue 4. 1984-02-28. PMID:6320247. |
at about the same time there are distinctive and partially irreversible alterations in dopaminergic innervations of the caudate nucleus, but not in mesolimbic dopamine innervation of the nucleus accumbens or in several other neurotransmitter systems. |
1984-02-28 |
2023-08-12 |
rat |
| D J Dooley, E Mogilnicka, A Delini-Stula, F Waechter, A Truog, J Woo. Functional supersensitivity to adrenergic agonists in the rat after DSP-4, a selective noradrenergic neurotoxin. Psychopharmacology. vol 81. issue 1. 1983-12-17. PMID:6415724. |
other behavioral experiments with agonists of the dopaminergic and serotoninergic systems indicated that these neurotransmitter systems were unchanged in dsp-4 animals. |
1983-12-17 |
2023-08-12 |
rat |
| F Ponzio, G Achilli, C Perego, G Rinaldi, S Alger. Does acute L-DOPA increase active release of dopamine from dopaminergic neurons? Brain research. vol 273. issue 1. 1983-11-23. PMID:6616231. |
l-dopa is believed to be decarboxylated by the residual striatal dopaminergic presynaptic terminals with formation of the putative neurotransmitter dopamine (da) and with increased availability of da at post-synaptic receptors. |
1983-11-23 |
2023-08-12 |
Not clear |
| A J Friedhoff, J C Mille. Prenatal psychotropic drug exposure and the development of central dopaminergic and cholinergic neurotransmitter systems. Monographs in neural sciences. vol 9. 1983-10-28. PMID:6310384. |
prenatal psychotropic drug exposure and the development of central dopaminergic and cholinergic neurotransmitter systems. |
1983-10-28 |
2023-08-12 |
Not clear |
| E S Garnett, G Firnau, C Nahmia. Dopamine visualized in the basal ganglia of living man. Nature. vol 305. issue 5930. 1983-10-21. PMID:6604227. |
in the first demonstration of the regional distribution of a neurotransmitter in the brain of conscious normal man, we show here that l-3,4-dihydroxyphenylalanine (l-dopa) labelled in the 6-position with the positron-emitting radionuclide fluorine-18, localizes specifically in the dopaminergic pathways of the human brain where its turnover could be measured atraumatically by positron emission tomography. |
1983-10-21 |
2023-08-12 |
human |
| O Barochovsky, A J Pate. Effect of central nervous system acting drugs on brain cell replication in vitro. Neurochemical research. vol 7. issue 9. 1983-02-25. PMID:6129583. |
compounds affecting noradrenergic, dopaminergic and serotoninergic neurotransmitter systems reduced the brain cell replication, measured in terms of the rate of [3h]thymidine incorporation into dna. |
1983-02-25 |
2023-08-12 |
Not clear |
| R P Sharma, C N Aldous, C H Far. Methylmercury induced alterations in brain amine syntheses in rats. Toxicology letters. vol 13. issue 3-4. 1983-01-27. PMID:7147263. |
the results suggested a sensitivity of dopaminergic pathways to methylmercury toxicity in the central nervous system and are consistent with interference with cholinergic mechanisms and neurotransmitter enzymes by methylmercury as previously reported. |
1983-01-27 |
2023-08-12 |
rat |
| S R George, G R Van Loo. beta-Endorphin alters dopamine uptake by the dopamine neurons of the hypothalamus and striatum. Brain research. vol 248. issue 2. 1983-01-07. PMID:6291701. |
in both hypothalamus and striatum there is dense innervation by the beta-endorphin and/or enkephalin neuronal systems, and physiologically relevant neuroregulatory interactions of these neurons occur with other important neurotransmitter neuronal systems, such as the dopaminergic tuberoinfundibular and nigroneostriatal systems. |
1983-01-07 |
2023-08-12 |
rat |
| S C Fung, Y C Kong, D M La. Prenatal development of gabaergic, glycinergic, and dopaminergic neurons in the rabbit retina. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 2. issue 11. 1983-01-07. PMID:6292378. |
the main findings from our studies on the emergence and maturation of neurotransmitter systems in the rabbit retina are that, during normal development: (1) the commitments for certain neurons to become gabaergic, glycinergic, or dopaminergic are made prenatally; the maturation of these neurons, however, occurs postnatally; (2) specific accumulations of exogenously supplied transmitters by presumed retinal neurons were first observed autoradiographically around embryonic day 22 (e22) for gamma-aminobutyric acid (gaba), e25 for glycine, and e27 for dopamine, suggesting that putative gabaergic, glycinergic, and dopaminergic neurons are determined phenotypically at least by these days; (3) based upon the three transmitter-specific properties--uptake, synthesis, and release--the uptake property is generally the first to emerge, while the appearance of the other properties follows a precise and distinct temporal pattern for each of the transmitters studied; (4) for gabaergic and glycinergic systems, the emergence of k+-stimulated, ca2+-dependent release mechanisms occurs many days after the first appearance of the uptake properties; in contrast, the mechanisms for dopamine uptake and release emerge at about the same time; and (5) by our criteria, putative gabaergic and glycinergic amacrine cells are mature between postnatal day 10 (p10) and p12, around the time when the eyes first open and direction-selective ganglion cells can first be recorded; however, the dopaminergic neurons probably are not mature until about p24. |
1983-01-07 |
2023-08-12 |
rabbit |
| P R Sanberg, R F Mar. Long-term effects on motor activity induced by apomorphine or scopolamine after intracerebral injections of cycloheximide or glutamate shortly after hatching in chickens. Behavioural brain research. vol 5. issue 3. 1982-12-02. PMID:6126200. |
these preliminary results are consistent with the idea that amongst other effects neonatal injections of cycloheximide or glutamate may alter dopaminergic and cholinergic neurotransmitter mechanisms involved in motor behavior in birds. |
1982-12-02 |
2023-08-12 |
Not clear |
| H Schoemaker, T P Davis, N W Pedigo, A Chen, E S Berens, P Ragan, N C Ling, H I Yamamur. Identification of beta-endorphin-6(16-17) as the principal metabolite of des-tyrosin-gamma-endorphin (DTgammaE) in vitro and assessment of its activity in neurotransmitter receptor binding assays. European journal of pharmacology. vol 81. issue 3. 1982-12-02. PMID:6126374. |
neurotransmitter receptor binding experiments showed that beta-endorphin-(6-17) was inactive at central dopaminergic, serotonergic, muscarinic, benzodiazepine and opiate receptors measured in vitro. |
1982-12-02 |
2023-08-12 |
rat |
| M L Barbaccia, A Bosio, L Lucchi, P F Spano, M Trabucch. Neuronal mechanisms regulating ethanol effects on the dopaminergic system. Life sciences. vol 30. issue 25. 1982-10-29. PMID:7202095. |
these data suggest that ethanol effects on the dopaminergic system are mediated by events involving other neurotransmitter systems. |
1982-10-29 |
2023-08-12 |
rat |
| I K Ho, K Fujimori, T P Huang, H Chang-Tus. Neurochemical evaluation of chlordecone toxicity in the mouse. Journal of toxicology and environmental health. vol 8. issue 5-6. 1982-06-24. PMID:6175763. |
on the basis of the data obtained so far, it is suggested that the dopaminergic pathway and its interaction with other neurotransmitter systems in the basal ganglia may be primarily involved in chlordecone-induced neurotoxicity. |
1982-06-24 |
2023-08-12 |
mouse |
| J L Bolaffi, I M Jackso. Regulation of thyrotropin-releasing hormone secretion from frog skin. Endocrinology. vol 110. issue 3. 1982-04-22. PMID:6120076. |
trh secretion is under dual neurotransmitter control with stimulatory noradrenergic and inhibitory dopaminergic components; other neurotransmitters were generally without effect. |
1982-04-22 |
2023-08-12 |
Not clear |
| E R Spindel, D J Pettibone, R J Wurtma. Thyrotropin-releasing hormone (TRH) content of rat striatum: modification by drugs and lesions. Brain research. vol 216. issue 2. 1981-09-25. PMID:6265032. |
thus trh levels in rat striatum are closely regulated by dopaminergic and other neurotransmitter systems. |
1981-09-25 |
2023-08-12 |
rat |
| W J Freed, D R Weinberger, L A Bing, R J Wyat. Neuropharmacological studies of phencyclidine (PCP)-induced behavioral stimulation in mice. Psychopharmacology. vol 71. issue 3. 1981-03-27. PMID:6109351. |
these findings suggest that chlorpromazine, clozapine, yohimbine, and methysergide may share a property that is unlike their primary known modes of action on dopaminergic, alpha-noradrenergic, and serotonergic neurotransmitter systems, and that this property accounts for their ability to block pcp. |
1981-03-27 |
2023-08-12 |
mouse |