| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D Samuel, L Kerkerian-Le Goff, U Kumar, M Errami, E Scarfone, A Nieoullo. Changes in striatal cholinergic, gabaergic, dopaminergic and serotoninergic biochemical markers after kainic acid-induced thalamic lesions in the rat. Journal of neural transmission. Parkinson's disease and dementia section. vol 2. issue 3. 1991-01-31. PMID:1979492. |
taken together, all these changes in neurotransmitter markers suggest that, directly through the thalamostriatal pathway or indirectly, the thalamus can exert a complex influence on striatal cholinergic and gabaergic neuronal functions as well as on the activity of dopaminergic and serotoninergic striatal afferent fibers. |
1991-01-31 |
2023-08-11 |
rat |
| M Halman, D S Goldbloo. Fluoxetine and neuroleptic malignant syndrome. Biological psychiatry. vol 28. issue 6. 1990-12-07. PMID:2223920. |
on reviewing the literature on the pathogenesis of nms, the authors hypothesize a facilitative role of the neurotransmitter serotonin (5-ht) in conjunction with central dopaminergic blockade in the precipitation of nms. |
1990-12-07 |
2023-08-11 |
Not clear |
| L Ereshefsky, T K Tran-Johnson, M D Watanab. Pathophysiologic basis for schizophrenia and the efficacy of antipsychotics. Clinical pharmacy. vol 9. issue 9. 1990-12-04. PMID:1977544. |
atypical antipsychotics may act by stabilizing presynaptic activity at a new set point, activating prefrontal dopaminergic systems and inhibiting mesolimbic systems, or exerting pharmacologic or functional effects on other neurotransmitter and neuropeptidergic systems. |
1990-12-04 |
2023-08-11 |
Not clear |
| P S Goldman-Rakic, M S Lidow, D W Gallage. Overlap of dopaminergic, adrenergic, and serotoninergic receptors and complementarity of their subtypes in primate prefrontal cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 10. issue 7. 1990-08-31. PMID:2165520. |
quantitative in vitro autoradiography was used to determine and compare the areal and laminar distribution of the major dopaminergic, adrenergic, and serotonergic neurotransmitter receptors in 4 cytoarchitectonic regions of the prefrontal cortex (walker's areas 12, 46, 9, and 25) in adult rhesus monkeys. |
1990-08-31 |
2023-08-11 |
monkey |
| E A Gordon, T A Kohout, P H Fishma. Characterization of functional neuropeptide Y receptors in a human neuroblastoma cell line. Journal of neurochemistry. vol 55. issue 2. 1990-08-17. PMID:2164571. |
the receptors on sk-n-mc cells appeared to be specific for npy, as other neurotransmitter drugs, such as alpha-adrenergic, dopaminergic, muscarinic, and serotonergic antagonists, did not compete for either npy binding or npy inhibition of adenylate cyclase. |
1990-08-17 |
2023-08-11 |
human |
| M Manier, C Feuerstein, J G Passagia, P Mouchet, N Mons, M Geffard, J Thibaul. Evidence for the existence of L-dopa- and dopamine-immunoreactive nerve cell bodies in the caudal part of the dorsal motor nucleus of the vagus nerve. Journal of chemical neuroanatomy. vol 3. issue 3. 1990-08-13. PMID:1973044. |
these results led us to conclude that these tyrosine hydroxylase-positive cells were effectively of dopaminergic nature and therefore that dopamine is a neurotransmitter contained in some neurons of the dorsal motor vagal nucleus. |
1990-08-13 |
2023-08-11 |
rat |
| P M Whitaker-Azmitia, L J Molino, J Caruso, A V Sheme. Serotonergic agents restore appropriate decision-making in neonatal rats displaying dopamine D1 receptor-mediated vacillatory behavior. European journal of pharmacology. vol 180. issue 2-3. 1990-08-13. PMID:2365008. |
these data suggest that the serotonergic and dopaminergic neurotransmitter systems must be in a proper balance for appropriate decision-making behaviors to occur. |
1990-08-13 |
2023-08-11 |
rat |
| P L Smiley, M Johnson, L Bush, J W Gibb, G R Hanso. Effects of cocaine on extrapyramidal and limbic dynorphin systems. The Journal of pharmacology and experimental therapeutics. vol 253. issue 3. 1990-07-31. PMID:1972755. |
several peptidergic neurotransmitter systems, such as the dynorphin pathways, have been shown to be distal to and regulated by the postsynaptic activity of dopaminergic pathways; therefore, we evaluated the response of extrapyramidal and limbic dynorphin a1-17 (dyn) systems to cocaine by measuring dyn content in associated structures. |
1990-07-31 |
2023-08-11 |
Not clear |
| H Ishizawa, B Tabakoff, I N Mefford, P L Hoffma. Reduction of arginine vasopressin binding sites in mouse lateral septum by treatment with 6-hydroxydopamine. Brain research. vol 507. issue 2. 1990-06-20. PMID:2110843. |
the results suggest that a portion of septal vasopressin receptors are localized on the terminals of noradrenergic and, possibly, dopaminergic neurons, consistent with the hypothesis that certain neuroadaptive responses to vasopressin could be mediated by modulation of neurotransmitter release. |
1990-06-20 |
2023-08-11 |
mouse |
| J C Crabbe, D J Feller, E S Terdal, C D Merril. Genetic components of ethanol responses. Alcohol (Fayetteville, N.Y.). vol 7. issue 3. 1990-06-05. PMID:2184836. |
when tested for sensitivity to a number of drugs with specific effects on neurotransmitter systems, cold and hot mice did not differ in sensitivity to drugs affecting dopaminergic, alpha-adrenergic, or nicotinic acetylcholinergic systems. |
1990-06-05 |
2023-08-11 |
mouse |
| R M Booze, C F Mactutu. Developmental exposure to organic lead causes permanent hippocampal damage in Fischer-344 rats. Experientia. vol 46. issue 3. 1990-04-26. PMID:2311721. |
pharmacological probes of neurotransmitter system integrity suggested a functional and dose-dependent relationship between this behavioral hyperreactivity and hippocampal damage via cholinergic, but not dopaminergic, pathways. |
1990-04-26 |
2023-08-11 |
rat |
| S F Ali, G Ahmad, W Slikker, S C Bond. Effects of gestational exposure to phencyclidine: distribution and neurochemical alterations in maternal and fetal brain. Neurotoxicology. vol 10. issue 3. 1990-04-12. PMID:2576301. |
fetal dopaminergic and muscarinic cholinergic receptor binding and neurotransmitter concentrations were unaffected by prenatal pcp exposure. |
1990-04-12 |
2023-08-11 |
rat |
| T Beck, J Wenzel, K Kuschinsky, J Krieglstei. Morphine-induced alterations of local cerebral glucose utilization in the basal ganglia of rats. Brain research. vol 497. issue 2. 1990-01-11. PMID:2684341. |
part of these effects might be, in addition, due to an activation of dopaminergic neurons, since dopamine mainly acts as an inhibitory neurotransmitter. |
1990-01-11 |
2023-08-11 |
rat |
| F Auth, B Kiss, I Laszlovszky, E Lapi. Substituted ergolines: potential antipsychotics with unique profile. II. Neurochemical characterization. Polish journal of pharmacology and pharmacy. vol 40. issue 6. 1990-01-03. PMID:2479935. |
on the basis of the effects of the drugs on the mouse whole brain monoamine neurotransmitter and metabolite levels and neurotransmitter biosynthesis rates along with the receptor binding data we conclude that their actions are mainly related to the central dopaminergic system(s). |
1990-01-03 |
2023-08-11 |
mouse |
| R Testa, G Abbiati, R Ceserani, G Restelli, A Vanasia, D Barone, M Gobbi, T Mennin. Profile of in vitro binding affinities of neuroleptics at different rat brain receptors: cluster analysis comparison with pharmacological and clinical profiles. Pharmaceutical research. vol 6. issue 7. 1989-10-28. PMID:2571988. |
was examined for their in vitro interactions with 12 neurotransmitter binding sites in the rat brain (alpha- and beta-noradrenergic, dopaminergic, muscarinic, serotoninergic, histaminic, and opioid receptors, calcium channels, and serotonin uptake binding sites). |
1989-10-28 |
2023-08-11 |
rat |
| M B Youdi. Brain monoamine oxidase (MAO) B: a unique neurotoxin and neurotransmitter producing enzyme. Progress in neuro-psychopharmacology & biological psychiatry. vol 13. issue 3-4. 1989-08-21. PMID:2568664. |
it is now apparent that mao-b is capable of oxidizing inert non-polar amines such as mptp (n-methyl-4-phenyl-1,2,3,6, tetrahydropyridine) and milacemide (2-n-pentylaminoacetamide) into neuroactive substances giving rise to parkinson inducing dopaminergic neurotoxin, mpp+ and inhibitory amino acid neurotransmitter, glycine respectively. |
1989-08-21 |
2023-08-11 |
Not clear |
| W R Klem. Drug effects on active immobility responses: what they tell us about neurotransmitter systems and motor functions. Progress in neurobiology. vol 32. issue 5. 1989-07-18. PMID:2567528. |
the literature reviewed indicates that active immobility can be promoted by systemic injections of various neurotransmitter systems, as follows: (1) dopaminergic blockade of both d1 and d2 receptor subtypes. |
1989-07-18 |
2023-08-11 |
Not clear |
| W R Klem. Drug effects on active immobility responses: what they tell us about neurotransmitter systems and motor functions. Progress in neurobiology. vol 32. issue 5. 1989-07-18. PMID:2567528. |
among the major interactions of neurotransmitter systems that regulate immobility, are the following: (1) cholinergic-dopaminergic (cholinolytics disrupt catalepsy of dopaminergic blockade and dopaminergic agonists tend to disrupt cholinomimetic catalepsy). |
1989-07-18 |
2023-08-11 |
Not clear |
| N A Alie. [Effect of the neuromediator systems of the neostriatum on immunocompetent cells]. Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova. vol 74. issue 12. 1989-06-02. PMID:2907493. |
the stimulation of the rat neostriatum dopaminergic system (with apomorphine) or blocking of the gaba-ergic (with picrotoxin) and serotoninergic (with parachlorphenylalanin) systems increased the level of immunological indices, whereas the lesion of dopaminergic system (with 6-hydroxydopamine) or the activation of two latter neurotransmitter systems (with gaba and serotonin, resp.) |
1989-06-02 |
2023-08-11 |
rat |
| R M Guerrero, K A Shifra. Diagnosis and treatment of neuroleptic malignant syndrome. Clinical pharmacy. vol 7. issue 9. 1989-05-12. PMID:3240662. |
mechanisms believed to cause nms include alteration of central neuoregulatory mechanisms and neuroleptic-induced imbalance between central dopaminergic and gamma-aminobutyric acid neurotransmitter systems. |
1989-05-12 |
2023-08-11 |
Not clear |