| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G H Tjon, T J De Vries, E Ronken, F Hogenboom, G Wardeh, A H Mulder, A N Schoffelmee. Repeated and chronic morphine administration causes differential long-lasting changes in dopaminergic neurotransmission in rat striatum without changing its delta- and kappa-opioid receptor regulation. European journal of pharmacology. vol 252. issue 2. 1994-05-13. PMID:7908881. |
interestingly, whereas [3h]dopamine release remained significantly reduced for at least 3 weeks following morphine withdrawal in chronically treated (tolerant/dependent) rats, neurotransmitter release from dopaminergic nerve terminals gradually increased above control values following cessation of repeated morphine administration. |
1994-05-13 |
2023-08-12 |
rat |
| A Rothenberge. Psychopharmacological treatment of self-injurious behavior in individuals with autism. Acta paedopsychiatrica. vol 56. issue 2. 1994-04-18. PMID:8135118. |
this paper is part of a special section on 'self-injurious behavior and autism' and reports new data that variously support the suggested involvement of dopaminergic, serotoninergic and opiatergic neurotransmitter systems in the expression of self-injurious behaviour. |
1994-04-18 |
2023-08-12 |
Not clear |
| C Gilber. Low risk to certain diseases in aging: role of the autonomic nervous system and calcium metabolism. Mechanisms of ageing and development. vol 70. issue 1-2. 1993-12-21. PMID:8231292. |
maintained dopaminergic activity, as proposed for africans, coupled with low risk to certain disorders, confirms the experimentally demonstrated paramount importance of this neurotransmitter in retarding aging processes in animals. |
1993-12-21 |
2023-08-12 |
Not clear |
| E Ronken, A H Mulder, A N Schoffelmee. Interacting presynaptic kappa-opioid and GABAA receptors modulate dopamine release from rat striatal synaptosomes. Journal of neurochemistry. vol 61. issue 5. 1993-11-29. PMID:8228982. |
in conclusion, striatal dopamine release is under regulatory control of multiple excitatory and inhibitory neurotransmitter by activation of colocalized presynaptic receptors for excitatory amino acids, acetylcholine, dopamine, dynorphins, and gaba within the dopaminergic nerve terminals. |
1993-11-29 |
2023-08-12 |
human |
| A Wallnöfe. [Psychopharmacological models of drug dependence. Key role of the dopaminergic mesolimbic system]. Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis. vol 82. issue 37. 1993-11-04. PMID:8210861. |
however, other non dopaminergic neurotransmitter systems, e.g. |
1993-11-04 |
2023-08-12 |
Not clear |
| T Vuvan, M Geffard, P Denis, A Simon, J Nguyen-Legro. Radioimmunoligand characterization and immunohistochemical localization of dopamine D2 receptors on rods in the rat retina. Brain research. vol 614. issue 1-2. 1993-09-14. PMID:8348331. |
the retinal neurotransmitter dopamine (da), elaborated from intrinsic dopaminergic neurons as amacrine and interplexiform cells, is known to modulate several complex functions mediated by d1 and d2 receptors in the vertebrate retina. |
1993-09-14 |
2023-08-12 |
rat |
| E V Jorgensen, I D Schwartz, E Hvizdala, J Barbosa, S Phuphanich, D I Shulman, A W Root, J Estrada, C S Hu, B B Berc. Neurotransmitter control of growth hormone secretion in children after cranial radiation therapy. The Journal of pediatric endocrinology. vol 6. issue 2. 1993-09-10. PMID:8102303. |
assessment of neurotransmitter pathways in the irradiated children revealed significantly lower mean peak gh concentrations in response to 5 of the 6 substances tested compared to control children: alpha-adrenergic stimulation (clonidine), beta-adrenergic blockade (propranolol), cholinergic stimulation, dopaminergic stimulation (l-dopa), and gaba-ergic stimulation (valproic acid). |
1993-09-10 |
2023-08-12 |
Not clear |
| A Pletscher, M DaPrad. Pharmacotherapy of Parkinson's disease: research from 1960 to 1991. Acta neurologica Scandinavica. Supplementum. vol 146. 1993-08-18. PMID:8101413. |
subsequently, the role of dopamine as neurotransmitter and the importance of dopaminergic pathways for the control of extrapyramidal motricity were firmly established. |
1993-08-18 |
2023-08-12 |
rat |
| H K Choi, L Won, A Helle. Dopaminergic neurons grown in three-dimensional reaggregate culture for periods of up to one year. Journal of neuroscience methods. vol 46. issue 3. 1993-06-02. PMID:8097798. |
dopaminergic neurons grown in dialyzed serum in reaggregate cultures show an increase in neurotransmitter level over the first 2 months in culture, and these levels of dopamine are maintained or increased over the next 4-12 months. |
1993-06-02 |
2023-08-12 |
Not clear |
| B Driessen, W Reimann, H Giert. Effects of the central analgesic tramadol on the uptake and release of noradrenaline and dopamine in vitro. British journal of pharmacology. vol 108. issue 3. 1993-05-13. PMID:8467366. |
neurotransmitter release and uptake experiments were used to characterize the effects of tramadol on the central noradrenergic and dopaminergic systems. |
1993-05-13 |
2023-08-12 |
rat |
| J Ułas, C W Cotma. Excitatory amino acid receptors in schizophrenia. Schizophrenia bulletin. vol 19. issue 1. 1993-04-12. PMID:8383875. |
together with other neurotransmitter systems, for example, dopaminergic, the net effect of eaa receptor imbalances may be greater than changes in the individual receptors and their neurotransmitters. |
1993-04-12 |
2023-08-12 |
Not clear |
| S S Wolf, T M Hyde, D R Weinberge. Neurobiology of schizophrenia. Current opinion in neurology and neurosurgery. vol 6. issue 1. 1993-03-10. PMID:8428072. |
genetic factors appear to facilitate liability to schizophrenia, and dopaminergic and possibly other neurotransmitter systems may mediate clinical expression of the illness through newly recognized receptor subtypes. |
1993-03-10 |
2023-08-12 |
Not clear |
| A Płaźnik, R Stefański, W Pałejko, W Kostowsk. The role of accumbens serotonin in stress-induced locomotor suppression in rats. Polish journal of pharmacology and pharmacy. vol 44. issue 3. 1993-01-22. PMID:1470562. |
it is concluded that accumbens serotonin system does not seem to contribute to the balance in the activity of local dopaminergic and gabaergic neurotransmitter mechanisms, previously shown to mediate some behavioral effects of stressors. |
1993-01-22 |
2023-08-11 |
rat |
| M Mintz, L Reyneke, A de Villiers, R Allin, V Russell, W Daniels, G van der Spuy, A Jaffer, L Kellaway, R Dougla. Effect of amygdaloid kindling on [3H]dopamine and [14C]acetylcholine release from rat prefrontal cortex and striatal slices. Brain research. vol 592. issue 1-2. 1993-01-06. PMID:1450903. |
kindling therefore produced area specific changes in neurotransmitter systems giving rise to increased pro-convulsive cholinergic activity in the ventral striatum and decreased anti-convulsive dopaminergic activity in the prefrontal cortex. |
1993-01-06 |
2023-08-11 |
rat |
| M Navarro, J J Fernández-Ruiz, F Rodriguez de Fonseca, M L Hernández, M Cebeira, J A Ramo. Modifications of striatal D2 dopaminergic postsynaptic sensitivity during development of morphine tolerance-dependence in mice. Pharmacology, biochemistry, and behavior. vol 43. issue 2. 1992-12-22. PMID:1332081. |
striatal dopaminergic activity was evaluated by measuring: a) the ratio between the amounts of l-3,4-dihydroxyphenylacetic acid (dopac), the main intraneuronal metabolite of dopamine (da), and the neurotransmitter itself, as an index of presynaptic activity; and b) the number and affinity of d1 and d2 dopaminergic receptors, as well as the amount of their coupled second messenger, cyclic adenosine monophosphate (camp), as postsynaptic parameters. |
1992-12-22 |
2023-08-11 |
mouse |
| J Hartikka, M Staufenbiel, H Lübber. Cyclic AMP, but not basic FGF, increases the in vitro survival of mesencephalic dopaminergic neurons and protects them from MPP(+)-induced degeneration. Journal of neuroscience research. vol 32. issue 2. 1992-11-03. PMID:1357186. |
despite this decline in cell number, neurotransmitter uptake per neuron increased with time, indicating that the surviving dopaminergic neurons continued their biochemical differentiation while others degenerated. |
1992-11-03 |
2023-08-11 |
rat |
| S Trumpp-Kallmeyer, J Hoflack, A Bruinvels, M Hiber. Modeling of G-protein-coupled receptors: application to dopamine, adrenaline, serotonin, acetylcholine, and mammalian opsin receptors. Journal of medicinal chemistry. vol 35. issue 19. 1992-10-26. PMID:1328638. |
five cationic neurotransmitter receptors (serotonergic 5-ht2, dopaminergic d2, muscarinic m2, adrenergic alpha 2 and beta 2 receptors) were taken as prototypes and studied in detail. |
1992-10-26 |
2023-08-11 |
Not clear |
| J Knol. (-)Deprenyl-medication: a strategy to modulate the age-related decline of the striatal dopaminergic system. Journal of the American Geriatrics Society. vol 40. issue 8. 1992-08-27. PMID:1634730. |
(4) maintenance on (-)deprenyl facilitates the activity of the nigrostriatal dopaminergic neurons with remarkable selectivity, and this effect, too, is unrelated to either its effects on mao or on neurotransmitter uptake. |
1992-08-27 |
2023-08-11 |
rat |
| R Moratalla, H A Robertson, A M Graybie. Dynamic regulation of NGFI-A (zif268, egr1) gene expression in the striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 12. issue 7. 1992-07-30. PMID:1613551. |
these findings raise the interesting possibility that some of the well-known effects of dopaminergic stimulation on neuropeptide and neurotransmitter expression in the striatum may reflect particular combinatorial patterns of immediate-early gene activation. |
1992-07-30 |
2023-08-11 |
rat |
| A N Wadworth, P Chris. Co-dergocrine mesylate. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in age-related cognitive decline. Drugs & aging. vol 2. issue 3. 1992-07-17. PMID:1606351. |
nonetheless, it has been proposed that co-dergocrine mesylate has a dual effect on central monoaminergic neurotransmitter systems, compensating for both hyperactivity and deficits of the adrenergic, serotoninergic and dopaminergic systems. |
1992-07-17 |
2023-08-11 |
human |