| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F Ponzio, G Achilli, C Perego, G Rinaldi, S Alger. Does acute L-DOPA increase active release of dopamine from dopaminergic neurons? Brain research. vol 273. issue 1. 1983-11-23. PMID:6616231. |
l-dopa is believed to be decarboxylated by the residual striatal dopaminergic presynaptic terminals with formation of the putative neurotransmitter dopamine (da) and with increased availability of da at post-synaptic receptors. |
1983-11-23 |
2023-08-12 |
Not clear |
| A J Friedhoff, J C Mille. Prenatal psychotropic drug exposure and the development of central dopaminergic and cholinergic neurotransmitter systems. Monographs in neural sciences. vol 9. 1983-10-28. PMID:6310384. |
prenatal psychotropic drug exposure and the development of central dopaminergic and cholinergic neurotransmitter systems. |
1983-10-28 |
2023-08-12 |
Not clear |
| E S Garnett, G Firnau, C Nahmia. Dopamine visualized in the basal ganglia of living man. Nature. vol 305. issue 5930. 1983-10-21. PMID:6604227. |
in the first demonstration of the regional distribution of a neurotransmitter in the brain of conscious normal man, we show here that l-3,4-dihydroxyphenylalanine (l-dopa) labelled in the 6-position with the positron-emitting radionuclide fluorine-18, localizes specifically in the dopaminergic pathways of the human brain where its turnover could be measured atraumatically by positron emission tomography. |
1983-10-21 |
2023-08-12 |
human |
| O Barochovsky, A J Pate. Effect of central nervous system acting drugs on brain cell replication in vitro. Neurochemical research. vol 7. issue 9. 1983-02-25. PMID:6129583. |
compounds affecting noradrenergic, dopaminergic and serotoninergic neurotransmitter systems reduced the brain cell replication, measured in terms of the rate of [3h]thymidine incorporation into dna. |
1983-02-25 |
2023-08-12 |
Not clear |
| R P Sharma, C N Aldous, C H Far. Methylmercury induced alterations in brain amine syntheses in rats. Toxicology letters. vol 13. issue 3-4. 1983-01-27. PMID:7147263. |
the results suggested a sensitivity of dopaminergic pathways to methylmercury toxicity in the central nervous system and are consistent with interference with cholinergic mechanisms and neurotransmitter enzymes by methylmercury as previously reported. |
1983-01-27 |
2023-08-12 |
rat |
| S R George, G R Van Loo. beta-Endorphin alters dopamine uptake by the dopamine neurons of the hypothalamus and striatum. Brain research. vol 248. issue 2. 1983-01-07. PMID:6291701. |
in both hypothalamus and striatum there is dense innervation by the beta-endorphin and/or enkephalin neuronal systems, and physiologically relevant neuroregulatory interactions of these neurons occur with other important neurotransmitter neuronal systems, such as the dopaminergic tuberoinfundibular and nigroneostriatal systems. |
1983-01-07 |
2023-08-12 |
rat |
| S C Fung, Y C Kong, D M La. Prenatal development of gabaergic, glycinergic, and dopaminergic neurons in the rabbit retina. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 2. issue 11. 1983-01-07. PMID:6292378. |
the main findings from our studies on the emergence and maturation of neurotransmitter systems in the rabbit retina are that, during normal development: (1) the commitments for certain neurons to become gabaergic, glycinergic, or dopaminergic are made prenatally; the maturation of these neurons, however, occurs postnatally; (2) specific accumulations of exogenously supplied transmitters by presumed retinal neurons were first observed autoradiographically around embryonic day 22 (e22) for gamma-aminobutyric acid (gaba), e25 for glycine, and e27 for dopamine, suggesting that putative gabaergic, glycinergic, and dopaminergic neurons are determined phenotypically at least by these days; (3) based upon the three transmitter-specific properties--uptake, synthesis, and release--the uptake property is generally the first to emerge, while the appearance of the other properties follows a precise and distinct temporal pattern for each of the transmitters studied; (4) for gabaergic and glycinergic systems, the emergence of k+-stimulated, ca2+-dependent release mechanisms occurs many days after the first appearance of the uptake properties; in contrast, the mechanisms for dopamine uptake and release emerge at about the same time; and (5) by our criteria, putative gabaergic and glycinergic amacrine cells are mature between postnatal day 10 (p10) and p12, around the time when the eyes first open and direction-selective ganglion cells can first be recorded; however, the dopaminergic neurons probably are not mature until about p24. |
1983-01-07 |
2023-08-12 |
rabbit |
| P R Sanberg, R F Mar. Long-term effects on motor activity induced by apomorphine or scopolamine after intracerebral injections of cycloheximide or glutamate shortly after hatching in chickens. Behavioural brain research. vol 5. issue 3. 1982-12-02. PMID:6126200. |
these preliminary results are consistent with the idea that amongst other effects neonatal injections of cycloheximide or glutamate may alter dopaminergic and cholinergic neurotransmitter mechanisms involved in motor behavior in birds. |
1982-12-02 |
2023-08-12 |
Not clear |
| H Schoemaker, T P Davis, N W Pedigo, A Chen, E S Berens, P Ragan, N C Ling, H I Yamamur. Identification of beta-endorphin-6(16-17) as the principal metabolite of des-tyrosin-gamma-endorphin (DTgammaE) in vitro and assessment of its activity in neurotransmitter receptor binding assays. European journal of pharmacology. vol 81. issue 3. 1982-12-02. PMID:6126374. |
neurotransmitter receptor binding experiments showed that beta-endorphin-(6-17) was inactive at central dopaminergic, serotonergic, muscarinic, benzodiazepine and opiate receptors measured in vitro. |
1982-12-02 |
2023-08-12 |
rat |
| M L Barbaccia, A Bosio, L Lucchi, P F Spano, M Trabucch. Neuronal mechanisms regulating ethanol effects on the dopaminergic system. Life sciences. vol 30. issue 25. 1982-10-29. PMID:7202095. |
these data suggest that ethanol effects on the dopaminergic system are mediated by events involving other neurotransmitter systems. |
1982-10-29 |
2023-08-12 |
rat |
| I K Ho, K Fujimori, T P Huang, H Chang-Tus. Neurochemical evaluation of chlordecone toxicity in the mouse. Journal of toxicology and environmental health. vol 8. issue 5-6. 1982-06-24. PMID:6175763. |
on the basis of the data obtained so far, it is suggested that the dopaminergic pathway and its interaction with other neurotransmitter systems in the basal ganglia may be primarily involved in chlordecone-induced neurotoxicity. |
1982-06-24 |
2023-08-12 |
mouse |
| J L Bolaffi, I M Jackso. Regulation of thyrotropin-releasing hormone secretion from frog skin. Endocrinology. vol 110. issue 3. 1982-04-22. PMID:6120076. |
trh secretion is under dual neurotransmitter control with stimulatory noradrenergic and inhibitory dopaminergic components; other neurotransmitters were generally without effect. |
1982-04-22 |
2023-08-12 |
Not clear |
| E R Spindel, D J Pettibone, R J Wurtma. Thyrotropin-releasing hormone (TRH) content of rat striatum: modification by drugs and lesions. Brain research. vol 216. issue 2. 1981-09-25. PMID:6265032. |
thus trh levels in rat striatum are closely regulated by dopaminergic and other neurotransmitter systems. |
1981-09-25 |
2023-08-12 |
rat |
| W J Freed, D R Weinberger, L A Bing, R J Wyat. Neuropharmacological studies of phencyclidine (PCP)-induced behavioral stimulation in mice. Psychopharmacology. vol 71. issue 3. 1981-03-27. PMID:6109351. |
these findings suggest that chlorpromazine, clozapine, yohimbine, and methysergide may share a property that is unlike their primary known modes of action on dopaminergic, alpha-noradrenergic, and serotonergic neurotransmitter systems, and that this property accounts for their ability to block pcp. |
1981-03-27 |
2023-08-12 |
mouse |
| S La. Pathophysiology and pharmacotherapy of spasmodic torticollis: a review. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. vol 6. issue 4. 1980-07-12. PMID:94551. |
because of the heterogeneity of st, investigations aimed at establishing a neurotransmitter profile for each patient by observing the acute response to a test dose of drugs affecting cholinergic, dopaminergic, serotonergic, and gamma-aminobutyric acid systems may provide a more rational basis to the selection of treatment. |
1980-07-12 |
2023-08-11 |
Not clear |
| P A Nausieda, W J Weiner, H L Klawan. Dystonic foot response of Parkinsonism. Archives of neurology. vol 37. issue 3. 1980-04-17. PMID:7356417. |
although the precise pathophysiology of this movement disorder is unknown, its response to baclofen therapy suggests that neurotransmitter systems other than cholinergic or dopaminergic ones may be implicated. |
1980-04-17 |
2023-08-12 |
Not clear |
| S H Cha. Central neurotransmitter systems in the morphine suppression of jaw-opening reflex in rabbits: the dopaminergic system. Experimental neurology. vol 65. issue 3. 1979-10-26. PMID:38132. |
central neurotransmitter systems in the morphine suppression of jaw-opening reflex in rabbits: the dopaminergic system. |
1979-10-26 |
2023-08-11 |
Not clear |
| M B Lazarova, K S Roussino. On certain effects of dopaminergic agents in pentylenetetrazol convulsions. Acta physiologica et pharmacologica Bulgarica. vol 4. issue 3. 1979-07-25. PMID:751452. |
it is possible that the effects of some of the dopaminergic agents studied are realized through influencing the relationships between the dopaminergic system and other neurotransmitter systems (especially cholinergic, gaba-ergic and serotonin-ergic). |
1979-07-25 |
2023-08-11 |
mouse |
| J A Fix, C O Rutledg. Alterations in the buoyant density of noradrenergic and dopaminergic synaptosomes following neurotransmitter accumulation. Brain research. vol 159. issue 2. 1979-03-24. PMID:728811. |
alterations in the buoyant density of noradrenergic and dopaminergic synaptosomes following neurotransmitter accumulation. |
1979-03-24 |
2023-08-11 |
Not clear |
| A S Horn, C J Grol, D Dijkstra, A H Mulde. Facile syntheses of potent dopaminergic argonists and their effect on neurotransmitter release. Journal of medicinal chemistry. vol 21. issue 8. 1978-12-02. PMID:29125. |
facile syntheses of potent dopaminergic argonists and their effect on neurotransmitter release. |
1978-12-02 |
2023-08-11 |
rat |