| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sofia Corrêa Valladão, Angela Patricia França, Pablo Pandolfo, Alexandre Dos Santos-Rodrigue. Adenosinergic System and Nucleoside Transporters in Attention Deficit Hyperactivity Disorder: Current Findings. Neuroscience and biobehavioral reviews. 2024-06-16. PMID:38880409. |
dopamine receptors and transporters are not solely implicated in this imbalance, as evidence indicates that the dopaminergic signaling is modulated by adenosine activity. |
2024-06-16 |
2024-06-19 |
Not clear |
| Bianca A Schuster, Sophie Sowden, Alicia J Rybicki, Dagmar S Fraser, Clare Press, Lydia Hickman, Peter Holland, Jennifer L Coo. Disruption of dopamine D2/D3 system function impairs the human ability to understand the mental states of other people. PLoS biology. vol 22. issue 6. 2024-06-13. PMID:38870319. |
our secondary analyses suggest that dopamine modulates inference from mental and non-mental state animations via independent mechanisms, pointing towards 2 putative pathways underlying the dopaminergic modulation of mental state attribution: action representation and a shared mechanism supporting mentalising and emotion recognition. |
2024-06-13 |
2024-06-16 |
human |
| Pingping Song, Dimitri Krain. Diverse Functions of Parkin in Midbrain Dopaminergic Neurons. Movement disorders : official journal of the Movement Disorder Society. 2024-06-11. PMID:38858837. |
in pd patient neurons, disruption of this pathway on loss of parkin leads to defective recycling of synaptic vesicles and accumulation of toxic oxidized dopamine that at least in part explains preferential vulnerability of midbrain dopaminergic neurons. |
2024-06-11 |
2024-06-14 |
human |
| Christopher G Goet. Historical Perspectives of Parkinson's Disease: Early Clinical Descriptions and Neurological Therapies. Cold Spring Harbor perspectives in medicine. 2024-06-10. PMID:38858084. |
the discovery of dopaminergic deficits in parkinson's disease and the synthetic pathway of dopamine led to the first human trials of levodopa. |
2024-06-10 |
2024-06-14 |
human |
| Demetra Ballardin, Leila Makrini-Maleville, Alexander Seper, Emmanuel Valjent, Heike Rebhol. 5-HT4R agonism reduces L-DOPA-induced dyskinesia via striatopallidal neurons in unilaterally 6-OHDA lesioned mice. Neurobiology of disease. 2024-06-09. PMID:38852753. |
parkinson's disease is caused by a selective vulnerability and cell loss of dopaminergic neurons of the substantia nigra pars compacta and, consequently, striatal dopamine depletion. |
2024-06-09 |
2024-06-14 |
mouse |
| Eun Young Jang, Bong Hyo Lee, Jaesuk Yun, Chae Ha Yang, Seong Shoon Yoo. Effects of the Synthetic Cathinone α-Pyrrolidinobutiothiophenone (α-PBT) on Discriminative Stimulus Effects and Intracranial Self-Stimulation Thresholds in Male Rats. ACS chemical neuroscience. 2024-06-05. PMID:38838000. |
in a separate set of studies, we examined the dopaminergic mechanisms underlying the function of α-pbt as an interoceptive stimulus (17.8 mg/kg) by intraperitoneally injecting either the dopamine (da) d1 antagonist sch23390 (0.06 and 0.12 mg/kg) or the d2 antagonist eticlopride (0.05 and 0.1 mg/kg) 15 min before dd testing. |
2024-06-05 |
2024-06-08 |
rat |
| Tousif Jamal, Xuan Yan, Angelica da Silva Lantyer, Judith G Ter Horst, Tansu Celike. Experience-dependent regulation of dopaminergic signaling in the somatosensory cortex. Progress in neurobiology. 2024-06-04. PMID:38834131. |
these findings provide new insights into the mechanisms by which sensory experience shapes dopaminergic signaling in the brain and might help unravel the sensory deficits observed after dopamine depletion. |
2024-06-04 |
2024-06-07 |
human |
| Carmen Costas-Ferreira, Rafael Durán, Lilian R F Far. Evaluation of the potential role of glutamatergic, cholinergic, and nitrergic systems in the dopamine release induced by the pesticide glyphosate in rat striatum. Journal of applied toxicology : JAT. 2024-06-03. PMID:38828527. |
glyphosate (gly) is a pesticide that severely alters nigrostriatal dopaminergic neurotransmission, inducing great increases in dopamine release from rat dorsal striatum. |
2024-06-03 |
2024-06-05 |
rat |
| Tania Arora, Gaurav Sharma, Vikash Prashar, Randeep Singh, Arti Sharma, Harish Changotra, Jyoti Parkas. Mechanistic Evaluation of miRNAs and Their Targeted Genes in the Pathogenesis and Therapeutics of Parkinson's Disease. Molecular neurobiology. 2024-06-01. PMID:38823001. |
pd is mainly caused by the demolition of the primary dopamine neurotransmitter secretory cells and dopaminergic or dopamine secretory neurons in the substantia nigra pars compacta of the midbrain, which are majorly responsible for motor functions. |
2024-06-01 |
2024-06-03 |
Not clear |
| Giulia Sbrini, Veronica Mutti, Federica Bono, Zaira Tomasoni, Dounia Fadel, Cristina Missale, Chiara Fiorentin. 17-β-estradiol potentiates the neurotrophic and neuroprotective effects mediated by the dopamine D3/acetylcholine nicotinic receptor heteromer in dopaminergic neurons. European journal of pharmacology. 2024-05-31. PMID:38821163. |
17-β-estradiol potentiates the neurotrophic and neuroprotective effects mediated by the dopamine d3/acetylcholine nicotinic receptor heteromer in dopaminergic neurons. |
2024-05-31 |
2024-06-02 |
mouse |
| Giulia Sbrini, Veronica Mutti, Federica Bono, Zaira Tomasoni, Dounia Fadel, Cristina Missale, Chiara Fiorentin. 17-β-estradiol potentiates the neurotrophic and neuroprotective effects mediated by the dopamine D3/acetylcholine nicotinic receptor heteromer in dopaminergic neurons. European journal of pharmacology. 2024-05-31. PMID:38821163. |
dopaminergic neurons express an heteromer composed of the dopamine d3 receptor and the α4-β2 nicotinic acetylcholine receptor, the d3r-nachr heteromer, activated by both nicotine and dopamine d2 and d3 receptors agonists, such as quinpirole, and crucial for dopaminergic neuron homeostasis. |
2024-05-31 |
2024-06-02 |
mouse |
| Hideo Kato, Chihiro Shiraishi, Mao Hagihara, Hiroshige Mikamo, Takuya Iwamot. Association between voriconazole-induced visual hallucination and dopamine in an analysis of the food and drug administration (FDA) adverse event reporting system database. Scientific reports. vol 14. issue 1. 2024-05-31. PMID:38822123. |
this study investigated the frequency of visual hallucinations in patients treated with voriconazole alone or in combination with dopaminergic medicines or dopamine antagonists, using data collected from the food and drug administration adverse event reporting system (faers). |
2024-05-31 |
2024-06-02 |
Not clear |
| Hideo Kato, Chihiro Shiraishi, Mao Hagihara, Hiroshige Mikamo, Takuya Iwamot. Association between voriconazole-induced visual hallucination and dopamine in an analysis of the food and drug administration (FDA) adverse event reporting system database. Scientific reports. vol 14. issue 1. 2024-05-31. PMID:38822123. |
the frequency of visual hallucinations with voriconazole alone and in combination with a dopaminergic medicine (levodopa) or dopamine antagonists (risperidone and chlorpromazine) was compared using data from the faers between 2004 and 2023, using the reporting odds ratio (ror) with relevant 95% confidence intervals (ci). |
2024-05-31 |
2024-06-02 |
Not clear |
| Hideo Kato, Chihiro Shiraishi, Mao Hagihara, Hiroshige Mikamo, Takuya Iwamot. Association between voriconazole-induced visual hallucination and dopamine in an analysis of the food and drug administration (FDA) adverse event reporting system database. Scientific reports. vol 14. issue 1. 2024-05-31. PMID:38822123. |
the reference group comprised patients who had been administered voriconazole without dopaminergic medication or dopamine antagonists. |
2024-05-31 |
2024-06-02 |
Not clear |
| C Duncan Spencer, Persephone A Miller, Jesukhogie G Williams-Ikhenoba, Ralitsa G Nikolova, Melissa J Che. Regulation of the mouse ventral tegmental area by melanin-concentrating hormone. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024-05-28. PMID:38806249. |
we recently showed that mch suppresses dopamine release in the nucleus accumbens, which principally receives dopaminergic projections from the ventral tegmental area (vta), but the mechanisms underlying mch-regulated dopamine release are not clearly defined. |
2024-05-28 |
2024-06-03 |
mouse |
| Manxing Zou, Yulu Wu, Yudan Lan, Huanfang Xie, Haopeng Sun, Wenyuan Liu, Feng Feng, Xueyang Jian. Identification and optimization of nitrophenolic analogues as dopamine metabolic enzyme inhibitors for the treatment of Parkinson's disease. Bioorganic chemistry. vol 148. 2024-05-26. PMID:38797066. |
progressive loss of dopaminergic neurons leads to the depletion of the striatal neurotransmitter dopamine, which is the main cause of parkinson's disease (pd) motor symptoms. |
2024-05-26 |
2024-05-31 |
Not clear |
| Robert A McCutcheon, Lilian A E Weber, Matthew M Nour, Stephanie J Cragg, Philip M McGuir. Psychosis as a disorder of muscarinic signalling: psychopathology and pharmacology. The lancet. Psychiatry. 2024-05-25. PMID:38795721. |
dopaminergic receptor antagonism is a crucial component of all licensed treatments for psychosis, and dopamine dysfunction has been central to pathophysiological models of psychotic symptoms. |
2024-05-25 |
2024-05-31 |
Not clear |
| Fu-Li Zhang, Xiao-Ke Yang, Yu-Ting Qi, Si-Yu Tian, Wei-Hua Huan. Nanoelectrochemistry reveals how presynaptic neurons regulate vesicle release to sustain synaptic plasticity under repetitive stimuli. Chemical science. vol 15. issue 20. 2024-05-24. PMID:38784745. |
herein, nanoelectrochemistry using carbon fiber nanoelectrodes with excellent spatio-temporal resolution was applied for real-time monitoring of presynaptic vesicle release of dopamine inside single synapses of dopaminergic neurons, and exocytotic variations in quantity and kinetics under repetitive electrical stimuli. |
2024-05-24 |
2024-05-27 |
Not clear |
| Bronwyn Bridges, Jake Taylor, John Thomas Webe. Evaluation of the Parkinson's Remote Interactive Monitoring System in a Clinical Setting: Usability Study. JMIR human factors. vol 11. 2024-05-24. PMID:38787603. |
pd is typically treated with levodopa, an oral pill taken to increase dopamine levels, and other dopaminergic agonists. |
2024-05-24 |
2024-05-27 |
Not clear |
| Anne Rombaut, Danica Jovancevic, Raymond Ching-Bong Wong, Alan Nicol, Rune Brautaset, David I Finkelstein, Christine T O Nguyen, James R Tribble, Pete A William. Intravitreal MPTP drives retinal ganglion cell loss with oral nicotinamide treatment providing robust neuroprotection. Acta neuropathologica communications. vol 12. issue 1. 2024-05-22. PMID:38773545. |
these changes classically include decreased levels of dopamine, accumulation of alpha-synuclein in the brain and retina, and death of dopaminergic nigral neurons and retinal amacrine cells leading to gross neuronal loss. |
2024-05-22 |
2024-05-27 |
mouse |