| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Natalie Schroyens, Laura Vercammen, Burcu Özcan, Victoria Aurora Ossorio Salazar, Jonas Zaman, Dimitri De Bundel, Tom Beckers, Laura Luyte. No evidence that post-training dopamine D2 receptor agonism affects fear generalization in male rats. Journal of psychopharmacology (Oxford, England). 2024-07-28. PMID:39068641. |
the neurotransmitter dopamine plays an important role in the processing of emotional memories, and prior research suggests that dopaminergic manipulations immediately after fear learning can affect the retention and generalization of acquired fear. |
2024-07-28 |
2024-08-02 |
rat |
| Ann-Kathrin Weishaupt, Lysann Ruecker, Torben Meiners, Tanja Schwerdtle, Daiana Silva Avila, Michael Aschner, Julia Bornhors. Copper-mediated neurotoxicity and genetic vulnerability in the background of neurodegenerative diseases in C. elegans. Toxicological sciences : an official journal of the Society of Toxicology. 2024-07-27. PMID:39067045. |
furthermore, our study provides insight into the mechanisms underlying cu-induced neurotoxicity in pd models, including disruptions in dopamine levels, altered dopamine-dependent behavior and degraded dopaminergic neurons. |
2024-07-27 |
2024-08-02 |
caenorhabditis_elegans |
| Roger A Barker, Anders Björklund, Malin Parma. The history and status of dopamine cell therapies for Parkinson's disease. BioEssays : news and reviews in molecular, cellular and developmental biology. 2024-07-26. PMID:39058892. |
this data has shown that developing dopamine cells when transplanted in the brain of a pwp can survive long term with clinical benefits lasting decades and with restoration of normal dopaminergic innervation in the grafted striatum. |
2024-07-26 |
2024-07-29 |
human |
| Samuel J Gershman, John A Assad, Sandeep Robert Datta, Scott W Linderman, Bernardo L Sabatini, Naoshige Uchida, Linda Wilbrech. Explaining dopamine through prediction errors and beyond. Nature neuroscience. 2024-07-25. PMID:39054370. |
therefore, looking forward, we discuss the prospects for a unifying theory that respects the diversity of dopamine signaling and function as well as the complex circuitry that both underlies and responds to dopaminergic transmission. |
2024-07-25 |
2024-07-28 |
Not clear |
| He Cui, Chang Shu, Yuxuan Peng, Ziyun Wei, Xiao Ni, Linlin Zheng, Jianing Shang, Fu Liu, Jieyu Li. Long-life triclosan exposure induces ADHD-like behavior in rats via prefrontal cortex dopaminergic deficiency. Ecotoxicology and environmental safety. vol 282. 2024-07-24. PMID:39047361. |
mechanistically, tcs reduced dopamine (da) synthesis, release, and transmission, and increased reuptake in pfc, thereby reducing synaptic gap da levels and causing dopaminergic deficits. |
2024-07-24 |
2024-07-28 |
rat |
| Ming Li, Xue-Ke Yang, Jian Yang, Tong-Xia Li, Chi Cui, Xiang Peng, Jie Lei, Kun Ren, Jie Ming, Pei Zhang, Bo Tia. Ketamine ameliorates post-traumatic social avoidance by erasing the traumatic memory encoded in VTA-innervated BLA engram cells. Neuron. 2024-07-20. PMID:39032491. |
furthermore, activation or inhibition of dopaminergic projections from the ventral tegmental area to the bla effectively mimics or blocks the therapeutic effect of re-exposure with ketamine and is dopamine d2 receptor dependent. |
2024-07-20 |
2024-07-24 |
mouse |
| Cintia Klaudia Finszter, Róbert Kemecsei, Gergely Zachar, Ágota Ádám, András Csilla. Gestational VPA exposure reduces the density of juxtapositions between TH+ axons and calretinin or calbindin expressing cells in the ventrobasal forebrain of neonatal mice. Frontiers in neuroanatomy. vol 18. 2024-07-19. PMID:39026519. |
previous quantitative morphometric studies from our laboratory showed a marked reduction and defasciculation of the mesotelencephalic dopaminergic pathway of vpa treated mice, along with a decrease in tissue dopamine in the nucleus accumbens (nac), but not in the caudatoputamen (cpu). |
2024-07-19 |
2024-07-21 |
mouse |
| Katarzyna Czarzasta, Dorota Sztechman, Tymoteusz Zera, Malgorzata Wojciechowska, Agnieszka Segiet-Swiecicka, Liana Puchalska, Karol Momot, Ilona Joniec-Maciejak, Ewa Machaj, Elizabeth M Sajdel-Sulkowsk. Age- and sex-dependent cardiovascular impact of maternal perinatal stress and altered dopaminergic metabolism in the medulla oblongata of the offspring. American journal of physiology. Heart and circulatory physiology. 2024-07-19. PMID:39028279. |
a significant decrease in homovanillic acid, a dopamine metabolite and indicator of dopaminergic activity, was observed in adult stress-exposed female offspring. |
2024-07-19 |
2024-07-21 |
rat |
| Katarina Tomović Pavlović, Budimir S Ilić, Luisa Leitzbach, Kameliya K Anichina, Denitsa Yancheva, Aleksandra Živković, Anelia Ts Mavrova, Holger Stark, Andrija Smelcerovi. Bis(benzimidazol-2-yl)amine-based DPP-4 Inhibitors Potentially Suitable for Combating Diabetes and Associated Nervous System Alterations. Chemistry & biodiversity. 2024-07-13. PMID:39001610. |
the potential beneficial effects on dopamine synthesis and the survival of dopaminergic neurons could be mediated by dpp-4 inhibition. |
2024-07-13 |
2024-07-15 |
human |
| Ian Cone, Claudia Clopath, Harel Z Shouva. Learning to express reward prediction error-like dopaminergic activity requires plastic representations of time. Nature communications. vol 15. issue 1. 2024-07-12. PMID:38997276. |
the td algorithm has been traditionally mapped onto the dopaminergic system, as firing properties of dopamine neurons can resemble rpes. |
2024-07-12 |
2024-07-15 |
Not clear |
| Vrinda Jain, Phillip J M Liang, Sushmitha Raja, Meena Mikhael, Morven A Camero. Light activation of the dopaminergic system occurs after eye-opening in the mouse retina. Frontiers in ophthalmology. vol 3. 2024-07-10. PMID:38983102. |
dopaminergic amacrine cells in the adult retina release dopamine in response to light stimulation, however, the light-induced activity of these cells in during postnatal development is not known. |
2024-07-10 |
2024-07-12 |
mouse |
| Vrinda Jain, Phillip J M Liang, Sushmitha Raja, Meena Mikhael, Morven A Camero. Light activation of the dopaminergic system occurs after eye-opening in the mouse retina. Frontiers in ophthalmology. vol 3. 2024-07-10. PMID:38983102. |
our data suggests that dopaminergic cell activation and light-induced dopamine release in the retina is primarily driven by classical photoreceptors after eye-opening. |
2024-07-10 |
2024-07-12 |
mouse |
| Miguel Ribeiro, Jonas Campos, Tiffany S Pinho, Belém Sampaio-Marques, Sandra Barata-Antunes, Jorge Ribeiro Cibrão, Ricardo Araújo, Sara Duarte-Silva, Elsa Moreira, Rui A Sousa, Pedro M Costa, António J Salgad. Human platelet lysate supports SH-SY5Y neuroblastoma cell proliferation and differentiation into a dopaminergic-like neuronal phenotype under xenogeneic-free culture conditions. Biotechnology journal. vol 19. issue 7. 2024-07-10. PMID:38987218. |
furthermore, following treatment with retinoic acid (ra) and further stimulation with brain-derived neurotrophic factor (bdnf) and nerve growth factor beta (ngf-β), the percentage of sh-sy5y cells stained positive for dopaminergic neuronal differentiation markers (tyrosine hydroxylase [th] and dopamine transporter [dat]) was higher in hpl or fd-hpl than in fbs, and gene expression of dopaminergic markers th, dat, and dr2 was also detected. |
2024-07-10 |
2024-07-13 |
human |
| Sophia J Weber, Alex B Kawa, Alana L Moutier, Madelyn M Beutler, Lara M Koyshman, Cloe D Moreno, Jonathan G Westlake, Amanda M Wunsch, Marina E Wol. Dopamine transmission at D1 and D2 receptors in the nucleus accumbens contributes to the expression of incubation of cocaine craving. bioRxiv : the preprint server for biology. 2024-07-09. PMID:38979157. |
however, despite the importance of dopaminergic signaling in the nacc for motivated behavior, little is known about the role that dopamine (da) plays in the incubation of cocaine craving. |
2024-07-09 |
2024-07-12 |
rat |
| Dev Desai, Jekee Patel, Falak Saiyed, Himarshi Upadhyay, Prashant Kariya, Jitendra Pate. A Literature Review on Holistic Well-Being and Dopamine Fasting: An Integrated Approach. Cureus. vol 16. issue 6. 2024-07-06. PMID:38966464. |
popularly known as dopaminergic detox or dopamine fasting, it is a concept that aims at reducing dependence on instant satisfaction gratification and overstimulation to attain mental clarity, lessen anxiety, and be able to enjoy everyday events again. |
2024-07-06 |
2024-07-08 |
Not clear |
| Muhammad Abdullah, Shih-Hsien Lin, Li-Chung Huang, Nan-Tsing Chiu, Yen Kuang Yan. Fat loss and muscle gain: The possible role of striatal dopaminergic tone in determining the efficacy of physical exercise. Journal of the Formosan Medical Association = Taiwan yi zhi. 2024-07-04. PMID:38965009. |
striatal dopaminergic tone was assessed by measuring dopamine transporter availability using technetium-99 m labelled tropane derivative, [99mtc]trodat-1 (trodat), single-photon emission computed tomography, and body composition (fat and muscles mass) was analysed using bioelectrical impedance. |
2024-07-04 |
2024-07-11 |
Not clear |
| Charltien Long, Kwang Lee, Long Yang, Theresia Dafalias, Alexander K Wu, Sotiris C Masmanidi. Constraints on the subsecond modulation of striatal dynamics by physiological dopamine signaling. Nature neuroscience. 2024-07-03. PMID:38961230. |
it is thought that dopaminergic neurons drive certain behaviors by rapidly modulating striatal spiking activity; however, a view has emerged that only artificially high (that is, supra-physiological) dopamine signals alter behavior on fast timescales. |
2024-07-03 |
2024-07-10 |
mouse |
| Joohyun An, Minkyu Shin, Geunyoung Beak, Jinho Yoon, Seewoo Kim, Hyeon-Yeol Cho, Jeong-Woo Cho. Drug Evaluation of Parkinson's Disease Patient-Derived Midbrain Organoids Using Mesoporous Au Nanodot-Patterned 3D Concave Electrode. ACS sensors. 2024-07-02. PMID:38954790. |
after the treatment of pd midbrain organoids with levodopa, the drug for pd, the increase in dopamine level was detected due to the activation of dopaminergic neurons by the drug. |
2024-07-02 |
2024-07-06 |
human |
| Reem M Gahtani, Shoaib Shoaib, Umme Hani, R Jayachithra, Mohammad N Alomary, Waseem Chauhan, Roshan Jahan, Saba Tufail, Mohammad Azam Ansar. Combating Parkinson's Disease with Plant-Derived Polyphenols: Targeting Oxidative Stress and Neuroinflammation. Neurochemistry international. 2024-07-01. PMID:38950626. |
dopamine metabolism, mitochondrial dysfunction, and neuroinflammation in dopaminergic neurons have been implicated in the pathogenesis of parkinson's disease. |
2024-07-01 |
2024-07-04 |
Not clear |
| Chloé Halfhide, Tommie L Cammarano, Kevin A Anderson, Stefani M Galik, Julien Rossignol, Gary L Dunbar, Michael I Sandstro. Using Microdialysis to Monitor Dopaminergic Support of Limb-Use Control Following Mesencephalic Neurosphere Transplantation in a Rodent Model of Parkinson's Disease. Behavioural brain research. 2024-06-30. PMID:38945302. |
our laboratory previously demonstrated that transplanted dopaminergic cells can elicit skilled movement recovery known to depend on phasic dopamine release. |
2024-06-30 |
2024-07-03 |
human |