| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Renee F Keller, Tina Kazemi, Andrei Dragomir, Yasemin M Akay, Metin Aka. Comparison between dopaminergic and non-dopaminergic neurons in the VTA following chronic nicotine exposure during pregnancy. Scientific reports. vol 9. issue 1. 2020-07-27. PMID:30679632. |
several studies have shown that nicotine produces long-lasting effects on gene expression within many brain regions, including the ventral tegmental area (vta), which is the origin of dopaminergic neurons and the dopamine reward pathway. |
2020-07-27 |
2023-08-13 |
rat |
| Jin Zhang, Yong Wang, Yi Na Sun, Li Bo Li, Li Zhang, Yuan Guo, Tao Wang, Lu Yao, Li Chen, Jian Li. Blockade of calcium-permeable AMPA receptors in the lateral habenula produces increased antidepressant-like effects in unilateral 6-hydroxydopamine-lesioned rats compared to sham-lesioned rats. Neuropharmacology. vol 157. 2020-07-21. PMID:31251995. |
our findings indicate that blockade of lhb cp-ampars produces antidepressant-like effects, which attribute to decreased firing activity of lhb neurons and increased levels of dopamine and serotonin in the mpfc, and provide further evidence that lhb cp-ampars regulate the firing activity of pvta dopaminergic neurons and mrn serotonergic neurons indirectly via the rmtg. |
2020-07-21 |
2023-08-13 |
rat |
| Benjamin N Greenwoo. The role of dopamine in overcoming aversion with exercise. Brain research. vol 1713. 2020-07-20. PMID:30171838. |
the current review summarizes exercise adaptations in dopaminergic circuits that lead to a hyperdopaminergic state; during which dopamine release in the striatum is sensitized during exposure to non-exercise stimuli, even aversive stressors that do not typically activate reward-related dopamine circuits. |
2020-07-20 |
2023-08-13 |
Not clear |
| I Csoti, H Herbst, P Urban, D Woitalla, U Wüllne. Polypharmacy in Parkinson's disease: risks and benefits with little evidence. Journal of neural transmission (Vienna, Austria : 1996). vol 126. issue 7. 2020-07-20. PMID:31222606. |
medical treatment targeting the dopaminergic system alone may include up to five different compounds: l-dopa (in combination with a dopa decarboxylase inhibitor), a catechol-o-methyltransferase (comt) and a monoamine oxidase (mao-b) inhibitor and a dopamine agonist. |
2020-07-20 |
2023-08-13 |
Not clear |
| Mary Hongying Cheng, Luca Ponzoni, Tatiana Sorkina, Ji Young Lee, She Zhang, Alexander Sorkin, Ivet Baha. Trimerization of dopamine transporter triggered by AIM-100 binding: Molecular mechanism and effect of mutations. Neuropharmacology. vol 161. 2020-07-14. PMID:31228486. |
the study suggests the possibility of controlling the effective transport of dopamine by altering the oligomerization state of dat upon small molecule binding, as a possible intervention strategy to modulate dopaminergic signaling. |
2020-07-14 |
2023-08-13 |
Not clear |
| Danielle E Bolland, Amy E Moritz, Daniel J Stanislowski, Roxanne A Vaughan, James D Foste. Palmitoylation by Multiple DHHC Enzymes Enhances Dopamine Transporter Function and Stability. ACS chemical neuroscience. vol 10. issue 6. 2020-07-07. PMID:30965003. |
the dopamine transporter (dat) is a plasma membrane protein that mediates the reuptake of extracellular dopamine (da) and controls the spatiotemporal dynamics of dopaminergic neurotransmission. |
2020-07-07 |
2023-08-13 |
human |
| Sacnité Albarrán-Bravo, José Arturo Ávalos-Fuentes, Hernán Cortés, Marina Rodriguez-Sánchez, Norberto Leyva-García, Claudia Rangel-Barajas, David Erlij, Benjamín Florá. Severity of Dyskinesia and D3R Signaling Changes Induced by L-DOPA Treatment of Hemiparkinsonian Rats Are Features Inherent to the Treated Subjects. Biomolecules. vol 9. issue 9. 2020-07-06. PMID:31480516. |
we examined whether the severity of lid correlated with changes in dopamine 3 receptor (d3r) signaling because of the following: (a) d3r expression and the induction of lid are strongly correlated; and (b) dopaminergic denervation induces a qualitative change in d3r signaling in the snr. |
2020-07-06 |
2023-08-13 |
human |
| Alexis E Whitton, Jenna M Reinen, Mark Slifstein, Yuen-Siang Ang, Patrick J McGrath, Dan V Iosifescu, Anissa Abi-Dargham, Diego A Pizzagalli, Franklin R Schneie. Baseline reward processing and ventrostriatal dopamine function are associated with pramipexole response in depression. Brain : a journal of neurology. vol 143. issue 2. 2020-07-06. PMID:32040562. |
although these findings await replication, they suggest that measures of reward-related mesolimbic dopamine function may hold promise for identifying depressed individuals likely to respond favourably to dopaminergic pharmacotherapy. |
2020-07-06 |
2023-08-13 |
Not clear |
| Omar Collazo-Navarrete, David Hernández-García, Gilda Guerrero-Flores, René Drucker-Colín, Magdalena Guerra-Crespo, Luis Covarrubia. The Substantia Nigra Is Permissive and Gains Inductive Signals When Lesioned for Dopaminergic Differentiation of Embryonic Stem Cells. Stem cells and development. vol 28. issue 16. 2020-07-02. PMID:31140356. |
transplantation of dopaminergic (da) cells into the striatum can rescue from dopamine deficiency in a parkinson's disease condition, but this is not a suitable procedure for regaining the full control of motor activity. |
2020-07-02 |
2023-08-13 |
Not clear |
| Annika H Runegaard, Kathrine Louise Jensen, Gitta Wörtwein, Ulrik Gethe. Initial rewarding effects of cocaine and amphetamine assessed in a day using the single-exposure place preference protocol. The European journal of neuroscience. vol 50. issue 3. 2020-06-30. PMID:30044020. |
in rodents, only a single dose of cocaine or amphetamine is required to cause a marked increase in extracellular dopamine, induce hyperlocomotion and cause persistent plasticity changes within dopaminergic neurons of the ventral tegmental area (vta). |
2020-06-30 |
2023-08-13 |
mouse |
| Jacqueline D Keighron, JoLynn B Giancola, Rachel J Shaffer, Emily M DeMarco, Mark A Coggiano, Rachel D Slack, Amy Hauck Newman, Gianluigi Tand. Distinct effects of (R)-modafinil and its (R)- and (S)-fluoro-analogs on mesolimbic extracellular dopamine assessed by voltammetry and microdialysis in rats. The European journal of neuroscience. vol 50. issue 3. 2020-06-30. PMID:30402972. |
here, we have tested the effects of the clinically available (r)-enantiomer of mod on extracellular dopamine levels in the nucleus accumbens shell, a mesolimbic dopaminergic projection field that plays significant roles in various aspects of psychostimulant use disorders, measured in vivo by fast-scan cyclic voltammetry and by microdialysis in sprague-dawley rats. |
2020-06-30 |
2023-08-13 |
rat |
| Huiying Liu, Hao Wu, Ning Zhu, Zijie Xu, Yue Wang, Yan Qu, Jun Wan. Lactoferrin protects against iron dysregulation, oxidative stress, and apoptosis in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinson's disease in mice. Journal of neurochemistry. vol 152. issue 3. 2020-06-30. PMID:31442326. |
its pathological features are dopaminergic neuronal death in the substantia nigra (sn), and significant reduction in dopamine (da) content in the striatum. |
2020-06-30 |
2023-08-13 |
mouse |
| Christian P Mülle. Everything you always wanted to know about sex and dopamine, but were afraid to ask: An Editorial for 'No basal or drug-induced sex differences in striatal dopaminergic levels: a cluster and metaanalysis of rat microdialysis studies' on page 482. Journal of neurochemistry. vol 152. issue 4. 2020-06-30. PMID:31792978. |
everything you always wanted to know about sex and dopamine, but were afraid to ask: an editorial for 'no basal or drug-induced sex differences in striatal dopaminergic levels: a cluster and metaanalysis of rat microdialysis studies' on page 482. |
2020-06-30 |
2023-08-13 |
rat |
| Fanni F Geibl, Martin T Henrich, Wolfgang H Oerte. Mesencephalic and extramesencephalic dopaminergic systems in Parkinson's disease. Journal of neural transmission (Vienna, Austria : 1996). vol 126. issue 4. 2020-06-26. PMID:30643975. |
neurodegeneration of the nigrostriatal dopaminergic system and concurrent dopamine (da) deficiency in the basal ganglia represent core features of parkinson's disease (pd). |
2020-06-26 |
2023-08-13 |
Not clear |
| R Horowski, P-A Löschman. Classical dopamine agonists. Journal of neural transmission (Vienna, Austria : 1996). vol 126. issue 4. 2020-06-26. PMID:30805732. |
he was awarded the nobel price for the discovery of the crucial role of dopamine (da) as a neurotransmitter in the cns, thereby forming the basis for the symptomatic therapy of parkinson's disease (pd) with l-dopa and subsequently dopaminergic drugs. |
2020-06-26 |
2023-08-13 |
Not clear |
| Edna Grünblatt, Anna Maria Werling, Alexander Roth, Marcel Romanos, Susanne Walitz. Association study and a systematic meta-analysis of the VNTR polymorphism in the 3'-UTR of dopamine transporter gene and attention-deficit hyperactivity disorder. Journal of neural transmission (Vienna, Austria : 1996). vol 126. issue 4. 2020-06-26. PMID:30923918. |
attention-deficit hyperactivity disorder (adhd) has been postulated to associate with dopaminergic dysfunction, including the dopamine transporter (dat1). |
2020-06-26 |
2023-08-13 |
Not clear |
| Takeda Atsushi, Haruna Taman. New insight into Parkinson's disease pathogenesis from reactive oxygen species-mediated extracellular Zn Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). vol 61. 2020-06-26. PMID:32438294. |
oxidative stress induced by the auto-oxidation of dopamine has been implicated as a key cause of the selective loss of dopaminergic neurons. |
2020-06-26 |
2023-08-13 |
Not clear |
| Shilin Luo, Seong Su Kang, Zhi-Hao Wang, Xia Liu, Julia X Day, Zhiping Wu, Junmin Peng, Daxiong Xiang, Wolfdieter Springer, Keqiang Y. Akt Phosphorylates NQO1 and Triggers its Degradation, Abolishing Its Antioxidative Activities in Parkinson's Disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 37. 2020-06-25. PMID:31358653. |
the oxidative metabolism of dopamine and consequent oxidative stress are implicated in dopaminergic neuronal loss, mediating the pathogenesis of parkinson's disease (pd). |
2020-06-25 |
2023-08-13 |
mouse |
| Luana Martins de Carvalho, Juliana Lauar Gonçalves, Agatha Sondertoft Braga Pedersen, Samara Damasceno, Renato Elias Moreira Júnior, Tatiani Uceli Maioli, Ana Maria Caetano de Faria, Ana Lúcia Brunialti Godar. High-fat diet withdrawal modifies alcohol preference and transcription of dopaminergic and GABAergic receptors. Journal of neurogenetics. vol 33. issue 1. 2020-06-22. PMID:30516420. |
the result obtained with this model point out that the relation among high-fat diet consumption and alcohol intake appears to depend on the presence or absence of the diet when alcohol intake is evaluated, and that an imbalance in the mesocorticolimbic dopaminergic pathway, observed by the transcriptional regulation of the dopamine receptors (drd1/drd2) and gaba |
2020-06-22 |
2023-08-13 |
human |
| José Antonio Monreal, Fabrice Duval, Marie-Claude Mokrani, Said Fattah, Diego Pala. Differences in multihormonal responses to the dopamine agonist apomorphine between unipolar and bipolar depressed patients. Journal of psychiatric research. vol 112. 2020-06-22. PMID:30836201. |
the dopamine d2/d1 agonist apomorphine (apo) can be useful in the evaluation of dopaminergic function. |
2020-06-22 |
2023-08-13 |
Not clear |